Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
A recent study found that lower vaccination rates among diabetic minorities, particularly African-Americans and Hispanics, cannot be explained by socioeconomic factors. The researchers suggest that understanding shared social and cultural values may hold the key to addressing these racial disparities.
A UC Irvine study found that adding antioxidants to insulin therapy can improve its ability to reduce blood sugar and prevent organ damage. Treating rats with insulin alone only partially succeeded, but vitamins C and E spared sugars, proteins, and nitric oxide from attack.
A study found that conjugated linoleic acid (CLA) supplements reduced body mass and improved management of adult-onset diabetes. Higher CLA levels were linked to lower leptin levels, a hormone regulating fat levels.
Researchers found that using interactive techniques, such as checking patient recall and comprehension, can improve diabetes control without requiring longer visits. This technique is underused by physicians but holds great potential for improving patient outcomes.
Researchers have identified several genes necessary for fat accumulation in nematode worms, which are also present in humans. These findings provide a crucial platform to rapidly identify key proteins regulating fat formation, potentially leading to new therapies for obesity and diabetes.
Despite being enrolled in a clinical trial comparing anti-clotting agents, African American stroke patients show poor rates of awareness, treatment, and control of diabetes, hypertension, and high cholesterol. These findings are concerning, as heart disease and stroke can be prevented with vigilant risk factor management.
A new UC Davis study reveals that C-reactive protein (CRP) plays a key role in the formation of blood clots and plaque buildup in arteries, increasing the risk of heart attacks and strokes. High CRP levels can be reduced by losing weight, exercising regularly, or taking statin drugs.
Researchers found that hormone therapy (HRT) significantly reduced the risk of developing type 2 diabetes among postmenopausal women with coronary heart disease and impaired fasting glucose. The study, published in Annals of Internal Medicine, suggests HRT may have metabolic benefits that outweigh the risks for certain high-risk groups.
Scientists have developed a new mouse model of lipoatrophic diabetes, which reveals the genetic pathway underlying the disease. The study also suggests that leptin therapy may be effective in treating humans with lipoatrophic diabetes.
A new genetic test can identify patients with diabetes at high risk for heart disease, potentially saving lives through early intervention. Researchers analyzed the haptoglobin gene in a population-based study and found that individuals with one form of the gene were five times more likely to develop heart disease.
A study found that mailed health promotions reduced outpatient visits by an average of 4.84 visits among arthritis patients, while increasing visits for high blood pressure patients. The interventions generated significant savings, supporting the potential cost-effectiveness of health mailings for managing chronic conditions.
A study of 1.2 million Medicare beneficiaries found that those with multiple chronic conditions are 99 times more likely to be hospitalized than those with none. This highlights the importance of better-coordinated primary care in reducing hospitalizations and costs.
Researchers at the University of Melbourne discovered a key player in the brain's response to low glucose levels, shedding light on how diabetes and hypoglycemia are regulated. By studying Neuropeptide Y, scientists hope to develop new treatments for these conditions.
A recent study found that only a quarter of patients receive nutrition counseling during doctor visits, falling short of national nutritional objectives. Physicians can be trained to offer tailored nutrition messages, but more in-depth counseling is needed for optimal patient outcomes.
TZDs trigger a 'futile' cycle where glycerol kinase stores fatty acids faster than fat cells release them, leading to increased insulin sensitivity. Researchers also found that TZDs alter chemical signals produced by fat cells, potentially benefiting future anti-diabetes drug development.
Scientists have created mice that can eat rich, high-fat diets without accumulating fat or risking diabetes. The mice lack the SCD-1 gene, which produces an enzyme required for fat tissue production. Instead of storing excess fat, the mice metabolize it, increasing energy expenditure and oxygen consumption.
A UB researcher observed a significant correlation between air pollution and diabetes prevalence in the US, suggesting potential environmental toxins may contribute to the disease. The study found states with high TRI emissions had higher diabetes rates, while low-emission states had lower rates.
A recent study by UCSF researchers reveals that lower literacy is associated with worse health outcomes for diabetes patients, even after accounting for other factors. Patients with inadequate health literacy are more likely to experience complications such as diabetic retinopathy and have poorer blood sugar control.
Research by James P. Smith and Dana P. Goldman found that education level is a significant factor in adherence to treatment regimens, particularly for complex diseases like HIV and diabetes. The study suggests that education can help improve health outcomes by promoting better adherence to treatment plans.
A new study found that GLP-1 receptor agonists can increase heart rate and blood pressure in animals, suggesting potential risks for diabetes treatment. The findings may impact the use of these agents in humans with Type II diabetes.
A new study reveals that statins can cut the risks of heart attacks and strokes in people with diabetes, narrowed arteries, or a history of stroke. The findings recommend changing guidelines to consider statin use for anyone at increased risk of heart disease, regardless of cholesterol levels.
A study found that patients taking olanzapine were at risk of developing diabetes, including diabetic ketoacidosis, with severe symptoms and even death. The researchers identified 289 cases of diabetes linked to the drug, highlighting a potential link between atypical antipsychotics and metabolic disorders.
A study of 181 patients with acute myocardial infarction found that nearly 40% had impaired glucose tolerance at discharge and 31% had undiagnosed diabetes. The risk factors were independent predictors of abnormal glucose tolerance, suggesting a need for screening tests after heart attacks.
A study of 181 patients who had a heart attack found that 35% had impaired glucose tolerance at discharge, while 40% developed it three months later. High fasting blood glucose concentrations and abnormal glucose levels in red blood cells were also associated with impaired glucose metabolism.
In a large clinical trial, patients with impaired glucose tolerance who took acarbose were 25% less likely to develop type-2 diabetes than those taking placebo. Acarbose also helped reversion of impaired glucose tolerance to normal glucose tolerance. The main side effects were flatulence and diarrhea.
A recent study found that ulcer rates were similarly low in patients with diabetes and prior foot ulcers, regardless of the type of shoes they wore. The researchers suggest that careful attention by healthcare professionals may be more effective in preventing ulcers than therapeutic footwear.
Researchers at Stanford University have created diabetic fruit flies by destroying insulin-producing cells, allowing them to study the development of pancreatic cells. The fly model could help understand the origin of insulin-producing cells in people with Type I diabetes.
A 2-year study found that high-dose interferon beta-1b significantly reduced relapse rates and new brain lesions in patients with relapsing-remitting multiple sclerosis compared to interferon beta-1a. The treatment also showed a strong association between MS and type-1 diabetes in the Sardinian population.
Researchers found that diets rich in soy protein and flaxseed can decrease total cholesterol, triglycerides, and glucose levels in obese rats. Flaxseed also showed a greater effect on various parameters than soybean, suggesting potential benefits for humans.
Researchers found that diabetes causes a phase shift in the heart's circadian clock, leading to changes in gene expression and potentially disrupting the synchronization between stimulus and response. This alteration may contribute to contractile dysfunction and increased risk of heart failure in patients with diabetes.
A 10-year study of over 6,500 patients with diabetes undergoing major vascular operations revealed a mortality rate of only 1 percent. The study's findings contradict previous research and suggest that patients with diabetes should be offered the same surgical options as those without diabetes.
Researchers are studying abnormal beta cell function to better understand canine and feline diabetes. They found that certain proteins play a crucial role in insulin secretion, which may contribute to the development of diabetes.
Researchers report significant improvements in patients with rare fat disorders who received leptin replacement therapy, including reduced triglyceride levels and liver fat accumulation. The therapy also controlled severe insulin resistance and improved blood glucose levels in most participants.
A new nutrition education program designed for older adults with diabetes improved blood sugar control and reduced the risk of cardiovascular disease. The program, which included 10 weekly sessions, taught participants how to evaluate food labels and make informed dietary choices.
Regular intense exercise over nine months improved glucose metabolism in overweight individuals, with benefits persisting after cessation. The study found significant reductions in insulin levels and improvements in cardiovascular health.
A new interactive computer program will be developed to bridge the language barrier for Spanish-speaking diabetics, providing healthcare professionals with translation tools. The program will translate basic health questions and answers from English to Spanish and vice versa.
A recent study found that individuals with high self-efficacy tend to have better blood sugar control and adherence to their self-care regimens. The researchers' findings suggest that teaching self-care behaviors can have a greater positive impact when combined with interventions aimed at improving self-efficacy.
A VA study found that opportunistic screening for diabetes is likely more cost-effective and can be easily integrated into typical office visits. The approach takes advantage of the doctor-patient relationship, promoting better follow-up care for patients at risk of diabetes.
A simple blood test can identify millions of patients with previously undetected diabetes, according to a new study. The test, HgA1c, accurately indicates blood sugar levels over the previous two to three months and detects at least 75 percent of cases of diabetes.
A study of 1,507 people with diabetes found that 71% are aware of their high blood pressure and 57% take medication, yet control rates remain inadequate. Effective treatment strategies are needed to address the disparities in blood pressure control among people with diabetes.
A study published in Diabetes Care found that diabetic women aged 50-75 years had lower rates of mammograms compared to control subjects, with 78.1% vs. 84.9% participation rates. The researchers suggest that the added burdens of caring for patients with diabetes may be a contributing factor.
Research suggests that a single enzyme, 11beta hydroxysteroid dehydrogenase type 1 (11 beta HSD-1), is involved in the accumulation of visceral fat and metabolic symptoms. Increasing this enzyme's activity in fat cells leads to obesity, diabetes, and other diseases.
A new study suggests that smaller hospitals can perform heart bypass surgeries with similar outcomes to high-volume hospitals for low-risk patients. Moderate- and high-risk patients, however, should still seek major medical centers with high-bypass volumes to minimize mortality risk.
Researchers at Hadassah-Hebrew University Medical School and Peptor Ltd. successfully arrested the progression of Type I diabetes in newly diagnosed patients using DiaPep277, an experimental drug that alters immune cell behavior.
A study of internists found that physicians often do not follow best practices due to concerns about patient individuality. The study suggests that noncompliance with guidelines can be a valid reflection of questions about their usefulness and applicability.
A large study has found that retinal blood-vessel damage is associated with an increased risk of stroke. Damage to the small blood vessels in the retina was linked to a doubling of stroke risk, regardless of age, sex, or other health factors.
A study found that African Americans with diabetes often lack adequate blood sugar and cholesterol control, leading to increased risk of complications. Poor prevention and management habits are prevalent, with many participants failing to receive recommended exams or monitoring their glucose levels regularly.
A recent study by UT Southwestern Medical Center has identified a significant number of undiagnosed hypertension and diabetes cases in the Dallas County population. The project aims to reduce death and disability from coronary heart disease through analysis of collected data.
Research reveals antioxidant supplements can mitigate the negative effects of ozone gas on lung function. Additionally, tiny airborne particles are associated with increased risk of hospital admissions for heart disease among diabetics.
Research reveals a strong association between rheumatoid arthritis and smoking, with those consuming more cigarettes daily facing increased risk. Lifestyle factors such as insulin-dependent diabetes, late menstruation, and prolonged hair dye use also contribute to the development of rheumatoid arthritis.
Researchers at Dana-Farber Cancer Institute have identified a crucial protein called PGC-1 that regulates glucose production in the liver. This breakthrough could lead to new treatments for diabetes by targeting this protein with future drugs.
A double-blind, placebo-controlled study found that patients with diabetic neuropathy experienced significant pain reduction with Lamictal treatment. Almost half of the patients achieved a 50% reduction in pain, and most were able to reduce their need for additional pain medication.
A recent study found that diabetes markedly raises the long-term death rate of people with heart attacks, especially women. The study followed 1,935 men and women hospitalized for a heart attack for an average of 3.7 years after their initial hospitalization.
A new analysis of 27 studies reveals that depression is associated with increased numbers, severity and ratings of diabetes complications. The study suggests a complex relationship between depression and diabetes, where underlying mechanisms may be influenced by biological, social and psychological variables.
IDX1's role in regulating glucose levels and insulin sensitivity has been identified, shedding light on potential therapeutic targets. Further research is needed to fully understand the mechanisms by which IDX1 influences diabetes progression.
A study found significant differences in spinal cord area between patients with diabetic neuropathy and healthy controls. The research suggests potential new therapies for detecting neuropathic process at an earlier stage.
A UCSF study reveals that uninsured patients with chronic illnesses face significant challenges in managing their conditions, including poor symptom recognition and limited access to medication. This can lead to greater illness severity and premature death. Free community clinics are crucial for addressing these disparities.
Researchers at UNC-CH have successfully developed vaccines using plasmid DNA that can prevent and even halt the progression of insulin-dependent diabetes in laboratory mice. The study's findings offer new hope for treating this growing health threat in humans, with potential annual injections required.
A study found that 2.2% of adults with diabetes were undiagnosed, leading to more physician visits, hospital admissions, and unfavorable health outcomes compared to normoglycemic individuals.
A study published by the American Academy of Neurology found that diabetes and high blood pressure can lead to cognitive decline in middle-aged people. The research, which examined 10,963 participants aged 47-70, showed a modest but statistically significant association between these conditions and cognitive abilities.