Articles tagged with Infectious Diseases
Elsevier has launched a new journal called Epidemics, which will focus on infectious disease dynamics. The journal aims to bring together researchers from various disciplines and provide a platform for high-quality papers in this emerging field.
Researchers have developed a new technique to determine tumor methylation status in archived tissue samples, providing a potential biomarker for early cancer diagnosis and risk assessment. The technique uses high-resolution melting analysis and has been validated on archival and fresh tissues.
Researchers found that patients who lost at least 9% of body weight showed reversal of their liver damage, while those who lost 5% or more experienced improvement in insulin resistance and fat accumulation. Weight loss was the key factor in improving fatty liver disease.
A new clinical trial suggests that long-term use of candesartan may significantly reduce symptoms of genetic heart disease, including left ventricular hypertrophy. The study found no adverse effects of candesartan use and highlights the need for customized treatment protocols based on individual patient gene mutations.
Levels of drug-resistant TB in China are nearly twice the global average, with 10% resistant to first-line drugs. The prevalence varied greatly between provinces, with an average weighted mean of 9.3% among all cases.
A University of Michigan researcher found that men who overspend on consumer goods have higher mating intentions and past success in attracting mates. The study suggests an evolutionary link between financial consumption and mating behavior, with men competing for status and resources to attract partners.
Researchers developed a transgenic mouse model expressing mutant prion protein, resulting in a fatal neurological disorder. The discovery may help unravel the mystery of this progressive disease affecting humans and animals.
A study found that the World Health Organization's (WHO) budget allocations do not align with global disease burdens. The WHO allocated 87% of its budget to infectious diseases, while non-communicable diseases received only 12%. This disparity in funding is concerning, particularly for injuries and violence, which are largely underfunded.
A study found that undocumented immigrants with tuberculosis exhibit longer symptom durations and more severe symptoms before seeking care. This raises concerns about the value of improving access to healthcare for these individuals.
Researchers at Saint Louis University have identified an investigational vaccine that induces a better immune response and is more effective at protecting against tuberculosis. The vaccine uses a weakened TB germ from one of the strains of the current tuberculosis vaccine.
China faces a significant health and economic challenge due to rising chronic diseases, including high blood pressure and smoking. The country has an ageing population and increasing rates of obesity, diabetes, and cardiovascular disease, with tobacco use being a major factor in these trends.
A low-cost egg-beater-based centrifuge can separate plasma from blood in minutes, used to detect deadly infectious diseases common in developing countries. The device requires no training or electricity and can be sterilized with boiling water.
A new study published in BMC Infectious Diseases reveals a significant increase in human rabies cases in China since the new millennium. The researchers found that the number of cases jumped dramatically from 159 to 3,279 between 1990 and 2006, with most patients contracting the disease after being bitten by dogs.
New research from Saint Louis University found that combining nuclear medicine clinicians and treating physicians to interpret PET-CT scans reduces false positive results by 51%, resulting in fewer unnecessary biopsies. This collaboration improves scan accuracy, sparring patients from painful and potentially catastrophic complications.
A new system called HealthMap has been developed to gather, organize, and disseminate online intelligence on disease outbreaks. This can facilitate early outbreak detection, increase public awareness of disease outbreaks prior to formal recognition.
A new study found that Mexico's southern region has the highest rates of infectious and nutritional diseases, as well as non-communicable diseases such as heart disease and diabetes. The study also identified being overweight, high blood glucose, and alcohol use as major risk factors for these diseases.
A Saint Louis University study found that patients with advanced heart failure may not benefit from implantable cardiac devices due to their underlying illness. The researchers identified two red flags: prolonged hospitalization and use of inotropic therapy, which are associated with higher risk of in-hospital mortality.
Researchers develop model predicting disease outbreaks based on weather patterns and climate variability. The study shows an association between high temperature and daily incidence of cryptosporidiosis in Massachusetts, highlighting the need for better understanding of how climate affects disease spread.
Exposure to secondhand tobacco smoke increases the risk of severe infectious illnesses and hospital admissions in young children. Children born prematurely or with low birth weight are particularly vulnerable to these risks.
Women with a family member who has had a hernia or prolapse are more likely to develop the condition themselves. Lifestyle changes, such as avoiding heavy lifting and maintaining a healthy weight, can help reduce the risk of pelvic organ prolapse.
Researchers found that affluent college students attempt to trade sexual currency for provisions, such as tickets or study assistance. The study suggests that these behaviors are hard-wired and persist regardless of wealth or security.
Researchers developed a special filter that quickly removes prion proteins, causing mad cow disease and Creutzfeldt-Jakob disease, from blood. The device has been approved for use in Europe and is expected to be commercialized in Ireland and the UK in mid 2008.
A phase III study of 15,183 healthy infants found that two doses of an oral live attenuated human rotavirus vaccine reduced cases of severe gastroenteritis by 32% compared to placebo. The vaccine efficacy was 80.5-82.1% against the wild-type G1 rotavirus strain.
Researchers have developed an assay to identify antibodies specific to Mycobacterium avium complex (MAC), distinguishing MAC-related pulmonary disease from tuberculosis in under eight hours. The test showed high sensitivity and specificity, reducing the risk of misdiagnosis and inappropriate treatment.
A study by SLU cardiologist Melda Dolan found that ultrasound contrast agents are safe and beneficial for diagnosing life-threatening heart disease. The researchers examined nearly 24,000 patients who received contrast agents during echocardiograms and compared their results to those of approximately 6,000 patients without the agents.
A new study by researchers at the University of Southern California and University of Pennsylvania reveals that male infants in developed nations are more likely to die than female infants. The disparity has narrowed in recent decades due to medical advancements such as C-sections and intensive care units.
Research shows that men are more likely to eat meat and poultry products, including duck and veal, whereas women favor vegetables like carrots and tomatoes. Women also have a preference for dry foods and certain fruits, such as strawberries and blueberries.
The proportion of foodborne outbreaks linked to leafy green consumption has substantially increased over the past 35 years, despite a rise in leafy green consumption. Per capita availability of leafy greens was found to be a significant factor in this correlation.
Experts call for enhanced learning about health systems, focusing on financing, payment systems, and organizational structures. They propose global partnerships to allocate funding for operational research and knowledge discovery in health systems.
A new Saint Louis University study suggests that nursing home residents can form strong connections with both real dogs and robotic companions like Aibo. The research found that these interactions alleviate loneliness and attachment issues in residents.
A Saint Louis University study found that less than a quarter of physicians can accurately predict patients' six-month mortality from heart failure. The study highlights existing knowledge gaps and uncertainty among doctors about end-stage care options, including palliative measures and hospice referrals.
A study found genetically similar lice on 1,000-year-old Peruvian mummies, challenging the idea that all diseases were transmitted from the Old World to the New World at the time of Columbus. The discovery sheds new light on human migration patterns and may help understand the origins of epidemic typhus.
A University of Michigan study found that couples who express their anger and resolve conflicts tend to live longer than those who suppress their emotions. Researchers analyzed 192 couples over 17 years and found that those who both suppressed their anger had a higher mortality rate, with twice as many deaths compared to other groups.
Scientists have identified nine DNA variants that increase lupus risk in women, providing a potential diagnostic tool for early detection. The study, published in Nature Genetics, highlights the importance of genetic factors in lupus susceptibility and may lead to new treatments and a cure.
Research reveals hereditary hemochromatosis is more prevalent among men with the genetic marker C282Y, posing a significant risk for liver fibrosis and joint disease. The study emphasizes the need for careful clinical assessment to detect the condition in high-risk individuals.
A new study from the University of Michigan found that educational programs can significantly lower cardiac symptoms, help with weight loss and physical activity in female heart patients over 60. The research suggests that group programs are more effective for weight loss and self-directed programs are better for symptom management.
A RAND Corporation study found that nearly one-third of local health departments connected callers to a public health professional within 30 minutes, while nearly 40% had cases where no one reached a trained professional. The study highlights the importance of having live operators at all times to meet federal guidelines.
Researchers at SLU School of Medicine have found a way to prevent or reverse muscle weakness in myasthenia gravis by blocking the immune response that causes it. This breakthrough could lead to new treatments for related autoimmune disorders like arthritis and lupus.
Researchers at Weill Cornell Medical College have made a breakthrough by observing synaptic vesicle recycling in real time, laying to rest the 'resealable spout' theory of vesicular recycling. The study uses cutting-edge methods to show that neurotransmitter packets must be rebuilt after each cycle.
Researchers found that abnormally folded prion protein in brain tissue does not reliably predict disease infectivity; some highly infectious samples had nearly undetectable levels of abnormal PrP. This suggests alternative mechanisms or specific conformation of abnormal PrP may be responsible for prion diseases.
A major five-year study will analyze 32 common allergen sources, identifying T cell responses and potential epitope-based therapies. The project may lead to revolutionary new approaches for treating allergies, potentially reducing the need for lengthy desensitization treatments.
Researchers discovered that peroxynitrite plays a critical role in developing morphine tolerance. Therapeutic manipulation of peroxynitrite can prevent its formation or decomposition to maintain the pain-relieving effect of morphine, reducing side effects and improving patient outcomes.
Researchers in Norway analyzed TB cases between 1993 and 2005, finding little evidence of spread among native-born citizens. Instead, immigrants brought more strains, while native infections decreased, suggesting immigration does not significantly contribute to TB transmission.
Researchers at Saint Louis University School of Medicine discovered a key brain chemical that causes Parkinson’s disease. They found that dopamine itself is converted into DOPAL, which triggers the death of dopamine-producing cells and leads to Parkinson’s.
A new study suggests that firing clay in unvented kilns could be a significant source of exposure to dioxins, particularly for individuals who use the kilns regularly. The study found elevated levels of dioxins in two women who frequently used kilns in their homes.
Researchers identified different areas of risk-taking based on ancestral challenges, finding that fertility risks are the least taken and social status-related risks are the most. Men were consistently more risk-takers than women across various domains.
As China's population reaches 336 million over 60 by 2030, the country faces a growing burden of care for senior citizens. The one-child policy may leave some older Chinese without a family member to care for them, forcing them to rely on limited caregivers or facilities.
A study by University of Alberta researchers suggests that all children adopted from outside North America should be screened for tuberculosis. The study found that 40% of foreign-born children under five years old with TB in Canada were international adoptees, highlighting the importance of systematic screening.
A Saint Louis University study finds that pediatricians' efforts to encourage lifestyle changes in obese patients and their families are often futile due to a lack of motivation. Doctors recognize the challenges of changing patterns of behavior in low-income households with limited access to healthy food and time for physical activity.
A new study by Saint Louis University researchers found that patients' emotional well-being is a crucial factor in determining the success of hip surgery. The clinical test used to evaluate hip function was shown to be less effective than previously thought, highlighting the need for a more comprehensive approach to patient care.
Patients hospitalized with bacterial pneumonia face a higher risk of new or worsening heart problems, with nearly 20% experiencing a heart attack or major heart condition. The presence of heart disease significantly increased mortality from pneumonia.
Infection with hepatitis B causes between 500,000 and 1.2 million deaths worldwide each year, with around 22,000 cases in Europe. A universal childhood vaccination policy is recommended to protect children before they are at risk of infection.
Researchers are testing an oral insulin capsule taken by mouth once a day to delay or prevent type 1 diabetes in people at risk. The study's goal is to identify ways to rein in the autoimmune attack on beta cells, potentially preventing the disease.
Saint Louis University research found that a diet of 40% fat and high-fructose corn syrup leads to fatty liver disease and type II diabetes, even in sedentary mice
Researchers have discovered critical regions within prions that determine much of their behavior, providing a new framework for exploring prion biology. These regions, known as recognition elements, can be activated by environmental conditions and amino acid sequence alterations.
A new Saint Louis University study shows that young transplant patients who lose their federally provided insurance coverage are more likely to stop taking necessary anti-rejection drugs. This can increase the risk of losing the transplanted organ and even death.
Researchers at St. Jude Children's Research Hospital discovered the role of PanK2 enzyme in detecting fatty acid buildup in mitochondria, a crucial step in cellular energy production. This finding has significant implications for understanding and treating neurodegenerative diseases caused by mutations in the PANK2 gene.
A stable social structure in badgers can help control the spread of bovine tuberculosis (TB), ecologists have found. The study found that movement of individuals between groups is instrumental in driving disease dynamics at the population level.
A study validates the Infectious Disease Society of America's guidelines for classifying diabetic foot infections, confirming a simple system can predict hospitalization and amputation. The free online classification system will guide therapy and patient communication.
The International Association of National Public Health Institutes (IANPHI) will strengthen public health infrastructure globally, focusing on low-resource countries. The grant enables IANPHI to establish a peer-assistance model for developing national public health institutes.