A Scripps Research team found that inhibiting stress neurons may decrease alcohol consumption in comorbid cases of post-traumatic stress disorder (PTSD) and alcohol use disorder. However, this approach did not mitigate anxiety. The study suggests that CRF plays a role in alcohol use among those with comorbid PTSD and AUD.
A recent study investigated anomalous health incidents among US government personnel and their family members. The researchers found that individuals experiencing these incidents did not show significant differences in clinical measures compared to matched control participants, except for fatigue, posttraumatic stress, and depression.
Researchers at the University of Texas at Arlington have developed a method to determine the clinical potency of psilocybin and psilocin in Psilocybe cubensis mushrooms. This technique uses liquid chromatography with tandem mass spectrometry, allowing for accurate extraction and measurement of the strength of the mushrooms.
Researchers at UC San Diego discover that acute stress triggers a switch in neurotransmitters, leading to generalized fear responses. They also find that suppressing GABA production and using antidepressants can prevent this effect.
A new study published in the journal Stroke found that African American veterans with PTSD had a significantly higher risk of re-hospitalization after a stroke compared to those without PTSD. This was not observed among white veterans. The study highlights the importance of targeted care for high-risk populations and reducing modifiabl...
A new study combines virtual reality exposure with transcranial direct current stimulation to treat post-traumatic stress disorder in military veterans. The innovative approach shows significant reductions in PTSD symptom severity and accelerates psychological adjustment, offering hope for an effective treatment.
The American College of Physicians (ACP) emphasizes the need for policy efforts to address homelessness, recommending stable housing and adequate funding. The report also highlights the importance of providing targeted medical services and decriminalizing life-sustaining activities in public.
A randomized clinical trial found acupuncture to be clinically efficacious and favorably affect PTSD symptoms in combat veterans. The study suggests that further research is needed to explore the efficacy and mechanisms of acupuncture for PTSD treatment.
A study by Ohio State University Wexner Medical Center found that crisis response planning can rapidly reduce suicidal thoughts among U.S. military members and veterans receiving massed cognitive processing therapy for PTSD. The intervention was tested in a randomized controlled trial involving 157 participants, with promising results.
Researchers at Mount Sinai Hospital have discovered that circulating immune cells can be drawn to the brain during stress and alter emotional behavior. The study found that these immune cells release an enzyme called MMP8, which breaks down proteins in the brain and impairs social behavior.
A clinical trial is underway to help patients with opioid use disorder (OUD) and post-traumatic stress disorder (PTSD) stick with medication treatment. The trial uses a patient-administered wearable device that delivers mild electrical stimulation to alleviate symptoms of both conditions.
Black adults in the US suffer from short and very short sleep after exposure to news about police killings of unarmed Black individuals. The study's findings suggest that poor sleep health is another tragic byproduct of exposure to these events.
People with stroke mimics are at a higher risk of developing post-traumatic stress disorder (PTSD) than those with confirmed strokes. Researchers found that patients with stroke mimics experience significant psychological distress and increased cardiovascular health risks.
A study of 215 veterans found that nearly half experienced significant depression score drops, while about one quarter saw a halving of their scores. About 15% achieved full remission after six weeks of ketamine infusions, suggesting the treatment can provide substantial relief for those with complex mental health needs.
A pilot study demonstrates the effectiveness of a new treatment program for veterans and first responders struggling with post-traumatic stress disorder (PTSD). The program, called Warriors' Ascent, achieved a substantially lower dropout rate than traditional treatments, reducing depression, PTSD, and high-risk drinking in participants.
Researchers developed a new technology to track when brain cells shut off, providing insights into normal brain function and diseases like depression and Alzheimer's. The technique identifies a protein called pyruvate dehydrogenase that is rapidly changed immediately after brain cells are inhibited.
A meta-analysis of 10,600 patients reveals that psychological interventions are highly effective in treating PTSD following multiple traumatic events. Trauma-focused cognitive behavioural therapy is the first line of treatment recommended in national guidelines, offering improved patient and therapist outcomes.
A study published in the Journal of Traumatic Stress found that certain symptoms of post-traumatic stress disorder (PTSD) are associated with a higher risk of substance use among children after a natural disaster. The study identified irritable behavior and angry outburst symptoms as being linked to the greatest risk for coping through...
A study from Duke University found that people with PTSD have a significantly smaller cerebellum, especially in areas related to emotion and memory. Researchers hope this discovery will lead to targeted treatments and more research on the brain region's role in PTSD.
Stanford researchers found that ibogaine safely improves depression, anxiety and functioning among veterans with TBI. The study included 30 veterans who experienced significant improvements in PTSD symptoms, depression and anxiety after treatment.
A nationwide prospective study found a sharp increase in post-traumatic stress disorder (PTSD), depression, and anxiety in Israelis following the October 2023 Hamas attack. The study nearly doubled the prevalence of these conditions, which were already higher than those reported in previous studies on terrorist events.
Researchers have discovered a brain circuit that mediates panic disorder, consisting of specialized neurons that send and receive the neuropeptide PACAP. Inhibiting PACAP signaling reduces panic symptoms, offering promising findings for future treatments.
Online racial discrimination is associated with posttraumatic stress disorder symptoms, which increase the risk of suicidal ideation among Black adolescents. The study highlights the importance of considering these factors in understanding suicidal ideation in this population.
A new study found that trauma survivors who received comprehensive mental health support after discharge had significantly lower hospital readmission rates. Researchers analyzed data from 171 patients and found that those receiving standard care had nearly twice as many readmissions as those with the intervention.
A new study published in Neurology found that nearly 30% of caregivers for severe stroke patients experience high levels of anxiety, depression, or post-traumatic stress during the first year after hospital discharge. Post-traumatic stress was particularly common among Mexican American caregivers.
A study published in the Journal of Nursing Administration found that Transcendental Meditation significantly reduced PTSD, anxiety, and burnout in frontline nurses during the COVID-19 pandemic. The technique improved flourishing by 15% and decreased symptoms by more than half over a 3-month period.
A novel mental health risk screen for hospitalized patients accurately predicts mental health outcomes, with 10 items correctly identifying 75% of those who later developed mental health issues. A tailored recovery program can also be effective in reducing mental health problems after trauma, increasing health equity among historically...
Researchers found that traumatic experiences trigger highly individualized and fragmented brain activity, unlike normal memory formation. This difference may explain why PTSD patients struggle to recall traumatic events coherently.
A new study found that traumatic memories in people with PTSD are represented in the brain in a distinct way, deviating from regular memory processing. The hippocampus and posterior cingulate cortex regions showed different neural responses to traumatic and sad autobiographical memories.
A novel pilot study combines mindfulness and exposure therapy to reduce PTSD symptoms in cardiac arrest survivors, with 80% showing significant improvement. The treatment protocol also improved cardiovascular health behaviors, including sleep quality and physical activity.
A novel brain stimulation technique has shown significant improvement in patients with hard-to-treat depression, with 66% responding to treatment and nearly half achieving acute remission. The study's findings are promising, particularly for patients who have tried other treatments without success.
A study published in Nature Communications found that music-evoked emotions create boundaries between episodes, making them easier to remember. Fluctuating emotions help form separate and durable memories, even from neutral experiences. The research has great therapeutic promise for helping people with PTSD and depression.
A small molecule called YM022 has been discovered to block aversive memory formation in mice, offering a new direction for developing anti-depressants. The study found that YM022 suppressed neuroplasticity-caused aversive memory formation and reduced depressive behaviors in mice.
Researchers at CWRU's Trauma Center have developed a model called CoHealing to mitigate on-the-job stress for educators. The study found that with support and psychoeducation, teachers can ease symptoms of burnout, stress, and secondary traumatic stress disorder.
A new study finds that individuals with PTSD symptoms exhibit a blunted responsiveness to cortisol, leading to impaired fear extinction and other biological alterations. Researchers used a genetically selected rat model to demonstrate the causal link between low glucocorticoid levels and PTSD vulnerability.
Greater PTSD symptoms were associated with higher carotid atherosclerosis and brain small vessel disease among midlife women. Women carrying the APOEɛ4 gene showed poorer cognitive performance in response to PTSD.
A groundbreaking clinical trial launched by the U.S. Army aims to find new treatments for post-traumatic stress disorder (PTSD) in military personnel and veterans. The trial will test multiple drug candidates and examine biological indicators to determine potential treatments.
Researchers found associations between PTSD and dietary patterns, specifically a Mediterranean diet rich in plant-based foods and fish. The study identified Eubacterium eligens as a protective species that may help alleviate PTSD symptoms.
A study at Ohio State University found that a combination of ibogaine hydrochloride and 5-MeO-DMT significantly improved PTSD symptoms, depression, anxiety, and cognitive functioning in special operations forces veterans. The treatment also alleviated cognitive impairment linked to traumatic brain injury.
Researchers found that MDMA increased feelings of connection and oxytocin levels in volunteers, while methamphetamine also showed similar effects. These findings suggest potential therapeutic benefits for traditional talk therapy.
The latest American Psychiatric Association journals offer insights into depression and PTSD factors, as well as guidance on handling drugs laced with fentanyl. The October issues also feature a joint commentary on nuclear war's impact on health professionals.
A large-scale study confirms that playing Tetris for fifteen minutes can prevent psychological trauma in mothers after a difficult birth. The therapeutic activity was found to interfere with memory consolidation of traumatic images, thereby preventing the development of post-traumatic stress symptoms linked to childbirth.
A new study reveals that post-traumatic stress disorder (PTSD) symptoms are associated with poorer sexual functioning among midlife women. The research suggests that addressing PTSD symptoms is crucial for improving sexual health and functioning as women age.
A study published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging found that greater activation in the right inferior frontal gyrus predicts better recovery from early PTSD symptoms. This breakthrough suggests a potential role for cortical/cognitive regions in regulating fear and PTSD development.
SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeImaging analysis·DateSep 21, 2023
A new approach to PTSD treatment may involve targeting cerebellar inhibitory interneurons, which play a critical role in fear memory formation. The research found that these interneurons drive fear memory consolidation via learning-induced HCN plasticity.
A Northwestern University study found that endogenous cannabinoid molecules released by the brain during stress can calm it down. These molecules activate the same receptors as THC and may provide a natural coping response to stress.
Researchers found that wrongly accused Post Office Scandal victims experience high levels of clinically significant post-traumatic stress and depressive symptoms, regardless of conviction outcome. The study highlights the need for mental health support and reliable investigation practices within the criminal justice system.
Research finds ADHD is a risk factor for major depression, post-traumatic stress disorder, anorexia nervosa, and suicide attempts. The study used Mendelian randomization to establish potential links between ADHD and these disorders.
A study by Hebrew University researchers found that directly involved war veterans exhibited almost double the level of PTSD symptoms compared to indirectly active veterans. Parents of active veterans experienced heightened secondary traumatic stress, with mothers bearing a greater burden than fathers.
A recent brain single-cell study found that certain genes are expressed at varying levels in the dorsolateral prefrontal cortex of individuals with PTSD and MDD, suggesting dysregulated pathways. The research could lead to novel diagnostic markers and targeted treatments for these conditions.
Researchers at Vanderbilt University Medical Center will compare the effectiveness of ketamine and etomidate in critically ill adults undergoing tracheal intubation. The study aims to determine which medication helps patients survive or prevents symptoms of PTSD.
Researchers are exploring psychedelic-based treatments as a potential game-changer for patients with post-traumatic stress disorder (PTSD) and substance use disorders. Studies have shown improvements in symptoms of both conditions, offering new hope for those who have struggled with treatment-resistant disorders.
In a new study, Salk Institute scientists discovered that dopamine regulates anxious worm behavior in the presence of nipping predators. The findings illuminate how this dopamine-regulated brain pathway may be related to anxiety and could provide insight into human conditions like PTSD.
The use of psychedelics in mental health treatment is gaining traction, but concerns about patient safety and regulation need to be addressed. Psychedelic-assisted therapy shows promise in treating conditions like depression and PTSD, but more research is needed on dosages, settings, and guidelines.
A University of Chicago Education Lab study found that a school-based group counseling program can significantly reduce PTSD, anxiety, and depression among Black and Latina girls. The program, Working on Womanhood (WOW), was found to reduce PTSD symptoms by 22% among adolescent girls in Chicago neighborhood schools.
A new study from Iowa State University finds that adverse childhood experiences can increase vulnerability to PTSD, even after controlling for combat exposure. The researchers suggest that early trauma can affect coping mechanisms and social support networks, making individuals more susceptible to stressors.
A new American Heart Association scientific statement highlights the disproportionate burden of cardiovascular disease on AI/AN women. The study reveals that more than 60% of these women have suboptimal heart health when pregnant, increasing their risk of heart disease later in life.
Survivors of firearm injury experience chronic PTSD symptoms and poor health-related quality of life, emphasizing the need for comprehensive care. Screening for chronic kidney disease could be cost-effective for US adults starting at age 35.
A study by WVU researchers highlights the need for improved mental health programs for first responders, citing increased stress and stigma. The study recommends linking responders with culturally competent clinicians, establishing centralized organizations, and expanding research efforts to address these issues.
Researchers discovered a specific form of ubiquitin protein selectively involved in forming fear memories in female brains, providing a potential target for therapeutic treatments. The finding could lead to more effective treatment options for post-traumatic stress disorder (PTSD) in females.