A new stem cell study provides insight into how neurons from individuals with post-traumatic stress disorder (PTSD) respond to stress hormones. The research found that these cells are hypersensitive to the stress hormone hydrocortisone, which could help explain why some people develop PTSD after trauma exposure.
A UK study has found that officers with strong support networks and a sense of meaningful work have lower rates of Complex Post-Traumatic Stress Disorder (C-PTSD), highlighting the need for improvements in police working lives.
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Researchers found that personal experiences with COVID-19, such as contracting the virus or losing loved ones, were strong predictors of mental health symptoms. Exposure to pandemic-related media also played a significant role in psychological distress. The study suggests targeted interventions to prevent loss of life and curbing the s...
A new study found that dogs can differentiate between breath and sweat samples from people before and after a stress-inducing task with an accuracy of 93.75%. The researchers believe that dogs are able to detect changes in volatile organic compounds produced by humans in response to stress.
A new study found that medical cannabis users reported significant improvements in pain management, social functioning, and overall health. The majority of participants were able to stop or reduce their opioid use, with some experiencing a five-fold decrease in hydrocodone prescriptions.
A new study finds that post-traumatic stress disorder (PTSD) and externalizing psychiatric disorders, such as substance use disorders, are associated with a higher risk of premature death. The researchers discovered that a cellular marker called GrimAge, measured through DNA methylation patterns, is linked to adverse clinical outcomes ...
Researchers warn that pharmaceutical companies' pursuit of psychedelic treatments threatens Indigenous and counterculture traditions. Magic mushrooms have spiritual significance for many people, but corporations seeking patents and monopolies on these medicines are being criticized for their approach.
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A study of 1,970 Flint residents found over one-fifth met criteria for depression and nearly one-quarter for posttraumatic stress disorder five years after the water crisis. Only 34.8% received mental health services, but most who did utilize them.
Researchers at Linköping University discovered a biological mechanism that increases the strength of fear memories stored in the brain. This finding provides new knowledge on the mechanisms behind anxiety-related disorders and identifies shared mechanisms with alcohol dependence.
Researchers found that stressed mice exhibited decreased neuron excitability in the dorsal hippocampus, which may drive social avoidance, while resilient mice showed increased excitability. This difference was linked to changes in stress hormone receptors and HCN1 protein expression.
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Researchers used data from over 400,000 individuals to model genetic and environmental factors influencing common neuropsychiatric disorders. Gene-environment interactions accounted for a significant proportion of variability in some disorders, while others showed more substantial contributions.
A meta-analysis of 64 longitudinal studies found that mental health problems remained elevated globally during the pandemic, with North Americans suffering from increased anxiety and depression. In contrast, Latin America and Europe experienced higher rates of insomnia.
A study found that 47% of parents meeting criteria for post-traumatic stress disorder (PTSD) symptoms, compared to 12% of children with implantable cardioverter-defibrillators. The trauma triggered by a child's heart problems can affect the entire family.
Researchers found that certain hepatitis C medications, such as glecaprevir and pibrentasvir, improved PTSD symptoms in a national cohort of VA patients. The study suggests these medications could fill the gap in FDA-approved treatments for PTSD, offering new hope for US adults affected by this condition.
Researchers at Salk Institute discover a molecule called CGRP that enables neurons to bundle threatening sensory cues into a unified signal, conveying it to the amygdala. The study may lead to new therapies for fear-related disorders such as PTSD and autism.
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A new study from the University of Missouri-Columbia found that American military veterans are less willing to seek treatment for sleep and alcohol use problems compared to physical health issues. Discrimination experiences also play a significant role in reducing treatment-seeking among veterans of color.
A study by Tel Aviv University researchers found a unique oral microbiotic signature in the saliva of veteran soldiers with PTSD, which may help diagnose post-traumatic stress disorder objectively. The study also showed that people with PTSD exhibit the same picture of bacteria in their saliva as those who have experienced combat stres...
New research reveals that only 1 in 5 Syrian children living in refugee camps exhibit resilience to mental health problems. The study found that factors such as the child's environment, caregiver interactions, and access to resources significantly impact their ability to recover from war trauma.
A new analysis of service dog-veteran pairs found that lower dog excitability and closer relationships between veterans and their dogs are associated with reduced PTSD symptoms. Better mental health outcomes were also linked to perceptions of easy care for the dog and more frequent interactions initiated by the veteran.
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A study found that individuals with less hippocampus engagement are more likely to develop severe posttraumatic stress disorder (PTSD) symptoms. Those who exhibit greater defensive reactions to potentially threatening events also showed increased PTSD risk.
Research suggests that individuals with PTSD exhibit decreased activity in the hippocampus, leading to impaired threat reactivity and memory formation. This study reveals a significant interaction between hippocampal activity and physiological arousal in predicting PTSD symptoms.
Salk researchers identify neurotensin as a key molecule in the brain's valence assignment process, which associates good or bad feelings with memories. The discovery could lead to a better understanding of why some people retain more negative emotions than positive ones, and may pave the way for new therapeutic targets.
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A new study found that volunteer healthcare workers who served in field hospitals during the COVID-19 pandemic experienced high levels of secondary traumatic stress, but those with higher compassion satisfaction showed milder symptoms. The researchers also found that avoidant emotional coping tactics significantly increased burnout and...
A study by University of Toronto researchers found that childhood physical abuse is associated with chronic pain, diabetes, cancer, migraines, arthritis, and heart disease in later life. The trauma can influence both physical and mental health many decades after the event.
A study of 231 Vietnam Era veterans reveals that 71% describe at least one traumatic event, including combat exposure, adverse childhood experiences, and navigating a life-threatening illness. The findings underscore the importance of clinician-patient relationships and trauma-informed care in older adult healthcare.
A recent study published in Brain Stimulation reveals that non-invasive vagus nerve stimulation increases reaction times to negative images and decreases reactions to positive images. The findings have implications for the development of treatments for PTSD and other mental health conditions.
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The World Health Organization's International Classification of Diseases has introduced a new diagnosis for complex post-traumatic stress disorder (CPTSD), expanding the criteria for PTSD. CPTSD is characterized by excessive emotional responses, feelings of worthlessness, and difficulties in relationships.
A study led by Imperial College London researchers discovered that certain types of stress induce sleep in mice, which subsequently relieves anxiety. The findings suggest that a specific set of neurons detected and responded to stress hormone levels, inducing both NREM and REM sleep.
Middle-age women with PTSD may be at risk for accelerated cognitive decline, suggesting earlier screening is warranted. The study of 12,000 women found a significant association between PTSD and accelerated cognitive decline.
A new therapy called Cognitive Behavioral Therapy for Headache (CBTH) significantly reduced related disability in veterans following a traumatic brain injury. It also showed comparable reductions in co-occurring symptoms of post-traumatic stress disorder (PTSD), with low drop-out rates and ease of use for therapists.
Patients experiencing dissociative symptoms after trauma may be at high risk of developing severe post-traumatic stress, depression, anxiety, and social impairment. Early interventions are crucial for these individuals.
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Researchers found that unpredictable parental behaviors disrupt optimal brain circuit formation in children, leading to increased vulnerability to mental illness and substance abuse. Studies using mice and human infants suggest that predictable signals and environments are crucial for healthy brain development.
A survey of 89 countries found that 62% of emergency medicine professionals experienced burnout syndrome, with 31.2% showing two symptoms. The pandemic has worsened understaffing and limited resources, leading to lower-quality care and medical errors.
A new study from Aarhus University and Aarhus University Hospital – Psychiatry has found that Danish patients with mental disorders experienced a worsening of symptoms in connection with the invasion of Ukraine. The study analyzed over 500,000 clinical notes from psychiatric hospitals in Denmark and identified a sharp increase in clini...
Two studies found that approximately one in eight doctors experienced high levels of moral distress, which increased the risk of anxiety, depression, and burnout. Healthcare organizations can reduce moral distress by providing opportunities for discussing ethical concerns and supporting staff well-being.
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Researchers have discovered three unique brain subtypes indicating high, medium, and low susceptibility to chronic pain and trauma symptoms in veterans. The study provides an objective measurement of pain and trauma susceptibility and could lead to targeted and personalized treatments.
A machine-learning model developed by researchers at Massachusetts General Hospital predicts which US Army soldiers are at greatest risk of homelessness upon transitioning to civilian life. The study identifies lifetime depression, trauma, and PTSD as key predictors, allowing for targeted interventions to mitigate homelessness.
A new study published in Frontiers in Behavioral Neuroscience reveals that nine out of ten autistic women in France have suffered sexual violence, with most victims being assaulted multiple times at a young age. The findings highlight the need for improved prevention and care programs to address this vulnerable population.
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A study of 330 family members found significant posttraumatic stress disorder (PTSD) symptoms three months after their loved ones' hospitalizations. Family members with higher PTSD symptom levels reported more distrust of healthcare providers.
Researchers at Tokyo University of Science identify brain regions and signaling pathways involved in fear extinction via delta receptor activation. The study suggests a potential therapeutic agent for post-traumatic stress disorders by suppressing fearful memories.
A study published in Brain reveals a dedicated neural circuit responsible for post-sepsis anxiety and depression. The researchers identified a potential pharmacological treatment by silencing the amygdala circuit during sepsis, reducing the risk of developing anxiety disorders.
Researchers found that NYX-783, a newly discovered drug, modulates NMDA receptor activity in neurons to suppress traumatic memories and spontaneous recovery of PTSD. The drug was effective in reducing fear responses and improving treatment outcomes, particularly in female mice.
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A machine learning model has been trained to accurately identify individuals with post-traumatic stress disorder (PTSD) by analyzing text data. The model achieved an 80% accuracy rate in distinguishing between those with and without PTSD. This breakthrough could lead to the development of a cost-effective screening tool for health prof...
A new study from the University of Houston finds that firefighters with post-traumatic stress disorder (PTSD) are more likely to have relationship problems. The research, led by Donald A. Godfrey, discovered a link between PTSD symptom severity and difficulty regulating emotions in intimate relationships.
A new study by Harvard Medical School researchers found that people who survive firearm injuries face greater risks of mental health disorders, substance use disorders, and pain in the year following injury. The analysis showed significant increases in healthcare spending, with gunshot survivors averaging $2,495 more per month compared...
Researchers found that maternal post-traumatic stress disorder (PTSD) severity in early childhood predicts child somatisation at school age. The study highlights the importance of considering family trauma history in pediatric consultations to improve patient care.
A pilot study by UC San Diego School of Medicine found that eight weeks of mindfulness training significantly reduced symptoms of trauma and depression in individuals grieving from gun violence. Participants showed notable improvements in life satisfaction, with benefits lasting after the program concluded.
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Researchers report promising results from a phase 3 clinical trial of MDMA-assisted therapy for post-traumatic stress disorder (PTSD), with two-thirds of participants no longer meeting the diagnostic criteria. The therapy showed better effect sizes than selective serotonin reuptake inhibitors (SSRIs) and was equally effective in treatm...
Researchers from UBC Okanagan and the University of Exeter found ketamine to have significant anti-depressant and anti-suicidal effects in a comprehensive systematic review. The study suggests ketamine may be helpful in treating various disorders, including eating disorders, substance use, and anxiety.
A study published by Boston University researchers reveals that social interactions can activate vivid memories and elicit emotional responses. The study found that animals' fear memories were enhanced by observing a stressed cage mate, but not by direct physical interaction.
Syrian refugee women in Houston experience significantly higher mental stress, including depression and anxiety, due to displacement and social strain. They face challenges such as language barriers, unemployment, and financial insecurity, which contribute to their high-stress environment.
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Researchers from Tel Aviv University found that hyperbaric oxygen therapy (HBOT) relieves PTSD symptoms in treatment-resistant veterans, improving brain function and microstructure. The breakthrough study provides new hope for PTSD sufferers, offering an objective diagnostic tool and potential long-term improvements.
A study tracking 425 patients post-COVID-19 found high prevalence of cognitive deficits, psychiatric impairments, and significant memory decline. Researchers observed no correlation between the severity of the disease or socio-economic factors with psychiatric alterations, suggesting a possible link to delayed inflammatory processes.
Trauma centers in the US are increasingly screening and intervening for patients with alcohol and substance abuse issues, as well as post-traumatic stress disorder (PTSD) and suicidal ideation. A survey found that over 95% of trauma centers screen and intervene for high-risk patients, leading to significant reductions in re-entry rates.
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Adults with spinal cord injuries have a near-80% increased risk of developing psychological conditions compared to those without the injury. Chronic pain is equally negatively impacting mental health, associated with post-traumatic stress disorder and other mental health conditions in most cases.
A randomized study of over 1,000 people with PTSD and/or bipolar disorder shows that telehealth and integrated care models can improve treatment engagement and outcomes. Patients who received guidance from local clinic team members and in-person follow-up with nurses or social workers had better results.
A recent study by Oregon State University found that night shift nurses are more likely to suffer from poor sleep, PTSD, depression, anxiety, and inflammation. The researchers also discovered a significant disparity in sleep quality among Black nurses, highlighting the impact of systemic racism on their health.
A new study by Georgia State University reveals that COVID-19 traumatic stress may predict post-traumatic stress disorder (PTSD) symptoms, especially in individuals with a history of past trauma. The findings showed a positive association between COVID-19 traumatic stress and PTSD symptoms across racial groups, except for Asian Americans.
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A study found that preventing mental health problems among schoolchildren, particularly externalizing disorders, could have prevented grade repetition and dropout. The study involved 2,511 families with children aged 6-14 and showed that girls with externalizing disorders were more likely to be held back a grade.
A landmark VA study found that prolonged exposure was statistically more effective than cognitive processing therapy in easing PTSD symptoms, with most Veterans showing meaningful improvement from both treatments. The researchers recommended shared decision-making between clinicians and patients to select their preferred treatment.