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Expert comment: How studying fossilized parasites can contribute to knowledge of infectious diseases

Researchers have developed a database of parasite-host interactions among ancient ocean animals, shedding light on the evolution of biodiversity and the impact of parasitism on ecosystems. The study suggests that parasites can positively stabilize coastal ecosystems, making them more stable despite individual harm to hosts.

SourceUniversity of Missouri-Columbia·JournalPhilosophical Transactions of the Royal Society B Biological Sciences·TypeData/statistical analysis·DateNov 8, 2021

Coronavirus: Minimal transmission risk when playing football

A study by the Universities of Basel and Saarland found almost no risk of coronavirus infection in football players, contradicting previous assumptions about team contact risks. The research team collected data from over 1,300 cases and concluded that outdoor sports with minimal physical contact pose a very low risk of infection.

SourceUniversity of Basel·JournalBritish Journal of Sports Medicine·DateNov 2, 2021

What causes disease outbreaks?

A study by the University of Georgia's Center for the Ecology of Infectious Diseases identified contaminated water as the most common driver of large-scale zoonotic disease outbreaks. The researchers analyzed over 4,400 outbreaks and found that unusual weather patterns and changes in vector abundance were also significant contributors.

SourceUniversity of Georgia·JournalPhilosophical Transactions of the Royal Society of London (B )·DateOct 26, 2021

Environmental injustice, population density and the spread of COVID-19 in minority communities

Researchers found that population density and long-term exposure to air pollution were the two factors most significantly correlated with COVID-19 transmission rates. Disproportionately affecting communities with more minority residents, these factors were identified through computer modeling and analysis of data from 12 metropolitan a...

SourceWashington University in St. Louis·JournalEnvironmental Research Letters·TypeComputational simulation/modeling·DateOct 19, 2021

OSU study on African buffalo offers insights on persistence of highly contagious pathogens

A new OSU study on African buffalo offers insights into the persistence of highly contagious foot-and-mouth disease pathogens. Researchers found that carrier transmission among certain strains can allow them to persist in populations, highlighting the need for public health interventions to limit transmission and endemicity.

SourceOregon State University·JournalScience·TypeExperimental study·DateSep 30, 2021

Seven symptoms jointly predict COVID-19 diagnosis

Researchers developed a model using data from over 1.1 million volunteers to identify the 7 most informative symptoms for COVID-19 test allocation. The model predicted PCR positivity with high accuracy, resulting in potential 30% to 40% increase in eligible individuals and 70% to 75% detection of positive cases.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateSep 28, 2021

Computer model may offer way to limit the spread of MRSA in hospitals

A new computer model developed by Columbia University researchers accurately predicts the likelihood of individuals being colonized with MRSA in hospital settings. The model identifies asymptomatic carriers, who are responsible for most of the spread, and suggests targeted interventions to control infections.

SourceColumbia University's Mailman School of Public Health·JournalProceedings of the National Academy of Sciences·TypeComputational simulation/modeling·DateSep 7, 2021

Researchers aim to optimize disease prevention in prison populations with rapid testing

Researchers explored optimizing disease control in prisons using rapid tests, identifying the optimal strategy to minimize costs and reduce infection. The study found that switching between full and no testing depends on various parameters, including contagion rates and test sensitivity.

SourceSociety for Industrial and Applied Mathematics·JournalSIAM Journal on Control and Optimization·TypeComputational simulation/modeling·DateAug 24, 2021

A mobility-based approach to optimize pandemic lockdown strategies

A new approach to modeling COVID-19 spread incorporates real-time data on people's movements, showing promise for optimal lockdown policies. The study suggests a balance between controlling the pandemic and minimizing economic costs can be achieved through mathematical models and Google mobility data.

SourcePLOS·JournalPLOS Computational Biology·TypeComputational simulation/modeling·DateAug 12, 2021

Organ transplant recipients significantly protected by COVID-19 vaccination

A recent study published in Transplant Infectious Disease found that COVID-19 vaccination provides strong protection against the virus for solid organ transplant recipients, with an almost 80% reduction in symptomatic cases. The study examined data from over 2,150 transplant patients and showed that nearly 70% of vaccinated patients re...

SourceUniversity of California - San Diego·JournalTransplant Infectious Disease·DateAug 5, 2021

Counting pandemic behavior to inform public health decisions

Researchers developed a new method to analyze video segments from live streams and estimate the prevalence of mask wearing. The protocol was successfully learned in under an hour and found reliable estimates of mask-compliance, with the potential to provide useful results for decision-makers within 48 hours.

SourceSociety for Disaster Medicine and Public Health, Inc.·JournalDisaster Medicine and Public Health Preparedness·TypeContent analysis·DateAug 5, 2021

Rethinking remdesivir

Researchers at University of California San Diego School of Medicine modified remdesivir to create an oral version that can be taken earlier in COVID-19 diagnoses. The revised drug proved effective and safe in cell and animal studies.

SourceUniversity of California - San Diego·JournalAntimicrobial Agents and Chemotherapy·DateAug 2, 2021

Combined effects of masking and distance on aerosol exposure potential

Researchers at Mayo Clinic found that wearing masks and maintaining physical distance significantly reduce the spread of COVID-19. The study showed that both disposable paper medical masks and two-layer cloth masks were effective in blocking aerosol particles, with increased distance reducing particle counts to near baseline levels.

SourceMayo Clinic·JournalMayo Clinic Proceedings·DateJul 29, 2021

Sick athletes passed virus to opponents, N.C. medical detective work revealed

A study by the University of North Carolina at Chapel Hill found that Duke University football players transmitted a Norwalk-like virus to their Florida State University opponents after eating contaminated food. The transmission was attributed to people touching each other's hands, uniforms, and possibly the football itself.

SourceUniversity of North Carolina at Chapel Hill·JournalNew England Journal of Medicine·DateOct 24, 2000

Reaching out: Innovative program screens for sexually transmitted diseases

Researchers at Washington University School of Medicine implemented an STD study program that set up booths in community gathering places to offer urine screening for chlamydia and gonorrhea. The program identified 24 people with the diseases, most of whom were unaware they were infected, and successfully treated 90% of them.

SourceWashington University in St. Louis·JournalSexually Transmitted Diseases·DateJun 11, 2000

University of Pittsburgh researchers develop new model to study HIV transmission in women

The University of Pittsburgh has developed a new organ culture model to study HIV transmission in women, which could lead to breakthroughs in barrier medications and prevention strategies. The model, described in the journal Nature Medicine, closely mimics the stratified cell layers present at sites of sexual transmission in women.

SourceUniversity of Pittsburgh Medical Center·JournalNature Medicine·DateMar 27, 2000

NIAID researchers identify new drugs to treat 'mad-cow' like disease in mice

Researchers at NIAID's Rocky Mountain Laboratories have identified a new class of compounds that slow the development of prion diseases in mice. The compounds, which include drugs used in cancer therapy, block the conversion of normal prion protein to an altered form, delaying disease progression. If successful in humans, this treatmen...

Mortician becomes infected with TB from cadaver

Researchers at Johns Hopkins Medicine reported a groundbreaking case of tuberculosis transmission from a cadaver to an embalmer, revealing the first documented instance of such a transmission. The study emphasizes the need for updated guidelines and precautions to prevent similar incidents in funeral homes.

SourceJohns Hopkins Medicine·JournalNew England Journal of Medicine·DateJan 25, 2000

Impact of race on hepatitis treatment, transmission of hepatitis from mother to infant, and missed diagnoses of liver disease described at meeting

Researchers found that African-American patients with chronic hepatitis C infection have a lower sustained response to antiviral therapy compared to Caucasians. Additionally, anti-HCV testing in infants may not be reliable until they are two years old, and the deletion of ALT testing has removed an important screening tool for liver di...

High HIV RNA levels major risk factor for mother-to-child HIV transmission

Researchers found that women with high HIV RNA levels in their blood transmitted the virus to their infants more often than those with low levels, highlighting the importance of treatment strategies aimed at reducing viral load. The studies also suggest that undetectable viral RNA levels can significantly reduce transmission risk.

SourceNIH/National Institute of Allergy and Infectious Diseases·JournalNew England Journal of Medicine·DateAug 4, 1999