Articles tagged with Gastroenterology
The American Gastroenterological Association has released a clinical care pathway to help women with inflammatory bowel disease (IBD) navigate family planning. The pathway emphasizes the importance of preconception planning, monitoring, and collaboration among healthcare providers to optimize outcomes.
The American Gastroenterological Association publishes a new clinical guideline for managing patients with mild-to-moderate ulcerative colitis. The guidelines recommend the use of oral and topical 5-aminosalicylates, rectal corticosteroids, and oral budesonide to promote high-quality care. However, the use of biologic therapies and imm...
Researchers at Ohio State University found that using a toilet stool can help people with constipation, bloating, and incomplete bowel movements. The study showed that 71% of participants experienced faster bowel movements and 90% reported less straining.
This special issue of Clinical Gastroenterology and Hepatology delves into the relationship between the gut microbiome and specific digestive diseases. Key findings include the role of the microbiome in inflammatory bowel disease, functional gastrointestinal diseases, colorectal cancer prevention, and pancreatic disease.
Research reveals a 6% annual increase in European colorectal cancer incidence rates among adults aged 20-39 years between 2008 and 2016. This trend is driven by increased risk factors such as sedentary lifestyles, obesity, and poor diets.
A global study found microplastics in every single stool sample from eight countries, with up to nine different types identified. The presence of microplastics may affect human health through bioaccumulation and transmission of toxic chemicals.
Opioid-induced constipation affects 40-60% of patients taking chronic opioid therapy. A new AGA guideline recommends starting with traditional laxatives as first-line agents, followed by PAMORA drugs if symptoms persist. These treatments aim to improve bowel symptoms without compromising pain relief.
The American Gastroenterological Association has launched a new initiative to foster opportunities for underrepresented minorities in gastroenterology research and career development. The program aims to provide training, mentoring, and leadership skills to promote diversity in the field.
A Mayo Clinic study found that specific gut bacteria, such as Phascolarctobacterium and Dialister, are associated with weight loss success and failure, respectively. The research suggests that individualized strategies may be needed to address the unique metabolic needs of each person.
A new study finds that video consultations between primary care physicians and specialists improve liver disease care and increase patient survival rates. Patients who participated in these consultations had a 54% higher survival rate compared to those without access to virtual consultations.
A study using oral-delayed release methylene blue during colonoscopy found a 56.3% detection rate for adenomas and carcinomas, nearly 9% higher than the standard of care. The tablet form reduces inconvenience and safety risks while improving adenoma detection rates.
A landmark study found that IBS patients who learned to control severe GI symptoms at home saw significant improvement, comparable to those treated with multiple clinic visits. The home-based behavioral treatment approach provided sustained relief for up to six months, overcoming a common barrier in rural healthcare.
The American Gastroenterological Association's new clinical guideline focuses on critical decisions made during initial management of acute pancreatitis. It recommends goal-directed fluid resuscitation, early oral feeding, and enteral versus parenteral nutrition to alter the course of disease and duration of hospitalization.
Boston University researcher Michelle T. Long has received a five-year, $1 million NIH grant to continue her research on non-alcoholic fatty liver disease (NAFLD). Her study will focus on the clinical and genetic traits associated with hepatic fibrosis in 3,500 participants.
Two cases of young children with severe esophageal injuries caused by swallowed lithium batteries from fidget spinners have been reported. The incidents highlight the potential danger of button batteries in children's toys, particularly those not specifically designed for kids.
Research presented at the Crohn's & Colitis Congress provides guidance for physicians to enhance IBD patient care. Studies show that better management of anemia improves overall outcomes, while IBD patients need better understanding of CRC screening intervals.
Researchers have made breakthroughs in IBD treatment with the approval of a new antibiotic and the use of Janus kinase inhibitors. These advancements aim to improve outcomes for patients who currently lack effective treatment options.
Studies show that home infusions can decrease infusion burden for selected patients and are cost-effective. Telemedicine may also improve outcomes but increases healthcare utilization. Urgent care access and patient education also lead to improved clinical outcomes and satisfaction.
The AGA FMT National Registry is the largest planned FMT study, tracking 4,000 patients for 10 years. The registry aims to provide a wealth of data on FMT's effectiveness and long-term effects, helping advance research and improve treatment outcomes.
A population-based study found a 22% reduction in stomach cancer risk among those aged 60 and over who received antibiotic-based treatment for H. pylori infection compared to the general population. The study suggests that treating this type of bacterial infection in older adults can help reduce their risk of developing gastric cancer.
A new AI-assisted endoscopic system has been shown to automatically identify colorectal adenomas during colonoscopy, demonstrating a sensitivity of 94% and specificity of 79%. The system enables real-time optical biopsy, allowing for the complete resection of adenomatous polyps and preventing unnecessary polypectomy.
A study of 13,864 participants found no convincing evidence linking PPI use to increased dementia risk. The research suggests that PPIs are safe for patients who require them for long-term treatment, and benefits may outweigh risks.
The task force ranked tests into three tiers according to the strength of the recommendation for average-risk people. Colonoscopy is highly sensitive for cancer and precancerous lesions, while fecal immunochemical testing (FIT) is non-invasive and lower-cost but must be repeated annually. The new guidelines also recommend starting scre...
A new study published in Cellular and Molecular Gastroenterology and Hepatology found that consuming unsaturated fat can lead to fatty liver disease, contrary to its previously touted health benefits. The research used mice fed diets supplemented with either saturated or unsaturated fat, revealing the latter can cause liver damage.
Researchers found that prebiotic fiber supplementation reduced annual projected body weight increase in overweight and obese children by nearly triple, compared to a placebo. The study also showed specific gut bacterial shifts with prebiotic intervention.
A recent study reveals that many children with inflammatory bowel disease (IBD) are not meeting the recommended daily intake of calcium and vitamin D. Experts warn that this can lead to poor bone health, development issues, and increased risk of permanent height deficits.
Researchers identified a new test to predict the severity of IBD in children based on faecal microbiota profiles. The study found that children with more extensive IBD had distinct gut microbiota profiles, including higher levels of Clostridiales and Proteobacteria.
A study presented at the ESPGHAN conference warns that young children on a vegan diet without proper medical and dietary advice may experience vitamin B12, calcium, zinc, and high-quality protein deficiencies. These deficiencies can lead to devastating health effects, including irreversible cognitive damage and death.
A study finds that gluten-free items have a significantly higher energy content and different nutritional composition compared to their gluten-containing counterparts. This could impact children's growth and increase the risk of childhood obesity.
A University at Buffalo study found that patient satisfaction among IBS patients is influenced by demographic, GI, and psychological factors beyond the quality of care. The researchers discovered that reassurance from gastroenterologists, rather than diagnostic tests, drives patient satisfaction in this population.
A new ambulatory monitoring device tracks gastric slow waves in patients with gastroparesis, enabling better understanding of the condition and its treatment. The device offers a window into stomach bioelectrical activity, revolutionizing digestive disease diagnosis and treatment.
Dr. Anil K. Rustgi has received the 2017 Julius Friedenwald Medal from the American Gastroenterological Association for his significant contributions to all aspects of gastroenterology, including research and clinical medicine. He is a leading expert in GI cancers and pre-cancerous changes.
The compilation presents state-of-the-art reviews on the pathogenesis, pathophysiology, and therapy of obesity, with a focus on the gastrointestinal tract. Key findings highlight the importance of diet composition, lifestyle interventions, and pharmacotherapy in weight management and metabolic health.
The American Gastroenterological Association recommends a tailored approach to PPI use for different conditions, weighing benefits against risks. Long-term PPI users should have their doses reevaluated regularly to minimize side effects.
The AGA has created an Obesity Practice Guide to guide and personalize innovative obesity care for safe and effective weight management. The program includes a framework focused on business operational issues related to the management of obese patients, published in Clinical Gastroenterology and Hepatology.
A research team developed ingestible prototypes that draw energy from gastric acid and provide power for nearly a week. They used zinc and copper as electrodes to harness energy from both the stomach and small intestine.
A new study by University of Florida researchers found that people seeking emergency treatment for food obstruction are 10 times more likely to do so during or after national holidays and sporting events. The study also identified turkey as the most common impacted food, followed by chicken and beef.
The new position paper provides recommendations on the timing and content of introducing complementary foods, as well as methods of feeding and specific dietary practices. It emphasizes the importance of ensuring adequate iron intake from complementary foods for all infants, especially those on vegetarian diets.
Professor J. Calvin Coffey reclassified the mesentery as a single, continuous structure connecting the intestine to the abdomen, leading to potential advances in surgeries and disease diagnosis. Further study of mesenteric science could result in less invasive procedures, faster recovery times, and lower costs.
A study published by the American Gastroenterological Association found that adults with inflammatory bowel disease (IBD) diagnosed in childhood have better educational levels and higher annual incomes compared to their healthy counterparts. This news may alleviate anxiety for parents of newly diagnosed patients, providing reassurance ...
The Rome IV classification introduces new diagnoses, emphasizes gut-brain interaction, and updates diagnostic criteria for functional gastrointestinal disorders. The Rome IV toolkit provides an interactive clinical decision-making tool for clinicians to optimize patient care.
A new study has found that faecal bacterial profiles can be used to predict which IBS patients are most likely to benefit from a low-FODMAP diet. The research identified differences in gut bacteria composition between those who responded and did not respond to the diet.
Researchers have developed a new imaging technique using hyperspectral imaging to detect and characterize early cancerous changes in the gastrointestinal tract. The technique, which involves increasing color channels during endoscopy, has the potential to improve specificity of lesion identification.
A recent study links a disease-associated microbial state to increased risk of developing IBD in genetically- and environmentally-susceptible individuals. Another study found that exposure to high altitude conditions triggers local acid sensing pathways leading to disease progression in IBD patients. Meanwhile, research highlights the ...
The American Gastroenterological Association (AGA) has launched a new PatientINFO Center to provide high-quality, readable information on colorectal cancer. The center addresses gaps in existing resources, offering detailed information on screening options, risk factors, and prevention strategies.
Researchers found that colorectal tumors have different regions with varying levels of epigenetic changes, which relate to the tumor's growth rate and aggressiveness. This heterogeneity can be used to predict prognosis and treatment resistance.
The AGA Fecal Microbiota Transplantation National Registry aims to protect patient safety while providing valuable data on the potential health risks of FMT. The registry will collect information from patients undergoing FMT at sites across the US, following them for up to 10 years to monitor adverse events and effectiveness.
The AGA Research Foundation and Pfizer Inc. are offering three research grants to support innovative research projects related to inflammatory bowel disease (IBD). The grants will provide $30,000 in funding for one-year pilot projects exploring new research directions.
The AGA Research Foundation has awarded $90,000 per year to three young investigators working on inflammatory bowel disease projects. The funding aims to improve patient care and advance the understanding of this serious digestive disease.
A team of UNC School of Medicine researchers played a critical role in amending diagnostic criteria questionnaires for functional GI disorders. The Rome IV publication updates the diagnostic tools available to clinicians, incorporating research on symptoms and patient experiences. These changes improve treatment options for millions of...
The low FODMAP diet has been found to be an effective treatment option for irritable bowel syndrome (IBS), with a significant body of evidence supporting its efficacy. The long-term effects of this dietary approach, however, require further investigation.
Researchers discovered that stem cells isolated from young mice can accelerate repair of stomach ulcers when transplanted into older mice. Additionally, studies redefined the role of the gut microbiome in inflammatory bowel disease and found potential therapeutic applications for acute alcoholic liver disease using a scavenger compound.
Researchers found that fecal microbiota transplantation effectively treated ulcerative colitis, with 27% of patients achieving symptom-free status. The study, which used a multi-donor approach, showed promise as an alternative treatment option for UC patients resistant to conventional therapies.
A study found that patients who ate solid foods before a colonoscopy had better bowel preparation and higher patient satisfaction rates. The low-residue diet included foods like eggs, cheese, and chicken breast, which made the process easier and less uncomfortable for patients.
UT Southwestern researchers challenge long-held beliefs on acid reflux damage, finding that inflammatory response and cytokine secretion are the main causes of esophageal damage. The study could lead to novel GERD treatments targeting these proteins.
At DDW 2016, AGA presents notable clinical practice data and basic science research on the gut microbiome. The conference features seven highlighted abstracts focusing on obesity management, hollow organ failure, and upper GI cancers.
A new study published in Clinical Gastroenterology and Hepatology found that celiac disease is most common among Americans from the Punjab region of India. The study analyzed over 400,000 intestinal biopsies and identified significant differences in celiac disease rates across various ethnic groups.
Recent CMGH articles suggest that targeting gut microbial populations may help prevent or treat Crohn's disease. A new study also identifies a potential therapy for chronic pancreatitis by reducing fibrosis and damage to the pancreas.
A new prognostic model for hepatocellular carcinoma, ITA.LI.CA, shows superior survival prediction in Italian and Taiwanese cohorts, integrating tumor staging, liver function, functional status, and alpha-fetoprotein level. The resulting score has concordance indices of 0.71 and 0.78 in internal and external validation cohorts.
A large cohort study in the UK found that antibiotic exposure before age 2 significantly increases early childhood obesity risk. The study suggests that antibiotics may alter the gut microbiome, predisposing children to obesity.