Articles tagged with Gastroenterology
A new study published in the UEG Journal found that young patients with inflammatory bowel disease (IBD) are at a higher risk of developing severe viral infections. Clinically active IBD and immunomodulators used to treat the condition are identified as main drivers of infection, with thiopurines increasing the risk by six times.
A new study found that 18 drug categories extensively impact the taxonomic structure and metabolic potential of the gut microbiome. Researchers identified eight categories increasing antimicrobial resistance mechanisms. The changes could increase risk of intestinal infections, obesity, and other conditions linked to the gut microbiome.
A major study across 195 countries found that global death rates for pancreatic cancer and incidence rates for colorectal cancer increased by 10% between 1990 and 2017. The study also reported significant increases in cases of inflammatory bowel disease (IBD) and a rise in obesity-related risk factors for pancreatic cancer.
A new study confirms FMT is effective in treating IBS with high response rates and symptom improvements, but selecting the right donor is crucial for success. The study used a 'super-donor' to produce high rates of clinical response and marked symptom improvements in patients with IBS.
A study found that plant-based diets and Mediterranean diets are associated with high levels of friendly gut bacteria, aiding nutrient production and SCFA energy for cells lining the colon. Plant protein helps biosynthesis of vitamins and amino acids.
A new national poll suggests that older adults are hesitant to try virtual health visits due to concerns about technology and quality of care. Despite this, many (64%) would be interested in telehealth options if they became unexpectedly ill while traveling or needed follow-up on previous care.
A large registry-based study found that current scoring systems have moderate reliability in predicting severe liver disease risk. The study identified individuals with normal scores as being at a very low risk of developing severe liver disease, highlighting the need for new methods to detect those at higher risk.
Researchers at MIT have developed a new gel-like material that can create a stable cushion for more than an hour, reducing the risk of tearing the colon lining during polyp removal. This innovation could greatly improve the safety and effectiveness of colonoscopies.
A large, multi-year randomized trial found no evidence to support claims that PPIs cause serious health issues such as pneumonia, chronic kidney disease, diabetes, and dementia. The study suggests that limiting prescriptions of PPI therapy is not appropriate due to the benefits outweighing the risks.
A study published at the 52nd Annual Meeting of ESPGHAN found that high fiber intake during pregnancy is linked to a decreased risk of childhood coeliac disease. The study, which assessed over 88,000 children, showed that mothers with higher fiber intake had lower rates of coeliac disease in their offspring.
A recent study published in Journal of Gastroenterology and Hepatology found that removing the gallbladder can reduce the risk of stroke by 40% in patients with gallstones. The study analyzed data from 310,712 patients and observed a lower risk regardless of age or medical conditions.
Research found that button batteries can cause gastric wall perforation and erosive injuries in 60% of cases, regardless of symptom presence or passage time. Clinicians should consider removing batteries promptly to avoid repeated ER visits and imaging.
A study published in Gastroenterology suggests that patients with IBS who have multiple intestinal and brain abnormalities experience more severe symptoms, making combination therapy a potential solution to improve treatment outcomes
A recent commentary suggests that treatment guidelines recommended by medical specialist organizations are more likely to lead to overdiagnosis, overtreatment, and increased healthcare costs. The authors argue that specialty bias and fee-for-service compensation models contribute to this issue.
Researchers have identified new pathways controlling inflammation in the gut and explored diet-based interventions to prevent C. difficile infections. Prebiotics may also help mitigate gastrointestinal toxicity from radiation treatment.
The American Gastroenterological Association has launched the AGA FORWARD Program to promote diversity in gastroenterology. The program's inaugural class of 10 Scholars includes underrepresented minority leaders who will receive mentorship and training to strengthen their research and management skills.
Studies presented at the Crohn's & Colitis Congress highlight advancements in treatments for patients with inflammatory bowel disease (IBD), including JAK inhibitors and biologics targeting immune cell trafficking. These therapies show promise for effective and safe oral therapeutic options for moderate to severe ulcerative colitis.
Studies highlight the importance of treating IBD as a whole person, including reproductive and mental health aspects. Patient-provider communication is key to improving health outcomes and addressing emotional exhaustion associated with IBD.
The American Gastroenterological Association has announced the 2019 recipients of the annual recognition awards, honoring outstanding contributions to the field of gastroenterology. The award winners include John I. Allen, MD, MBA, AGAF; Harry B. Greenberg, MD; and Timothy C. Wang, MD, AGAF.
A national study is comparing three FDA-approved treatments for fecal incontinence: biofeedback therapy, inert injectable compounds, and pacemaker stimulation. The five-year study aims to determine which treatment is most effective and safe for patients with moderate to severe fecal incontinence.
The American Gastroenterological Association has released a clinical care pathway to help women with inflammatory bowel disease (IBD) navigate family planning. The pathway emphasizes the importance of preconception planning, monitoring, and collaboration among healthcare providers to optimize outcomes.
The American Gastroenterological Association publishes a new clinical guideline for managing patients with mild-to-moderate ulcerative colitis. The guidelines recommend the use of oral and topical 5-aminosalicylates, rectal corticosteroids, and oral budesonide to promote high-quality care. However, the use of biologic therapies and imm...
Researchers at Ohio State University found that using a toilet stool can help people with constipation, bloating, and incomplete bowel movements. The study showed that 71% of participants experienced faster bowel movements and 90% reported less straining.
This special issue of Clinical Gastroenterology and Hepatology delves into the relationship between the gut microbiome and specific digestive diseases. Key findings include the role of the microbiome in inflammatory bowel disease, functional gastrointestinal diseases, colorectal cancer prevention, and pancreatic disease.
Research reveals a 6% annual increase in European colorectal cancer incidence rates among adults aged 20-39 years between 2008 and 2016. This trend is driven by increased risk factors such as sedentary lifestyles, obesity, and poor diets.
A global study found microplastics in every single stool sample from eight countries, with up to nine different types identified. The presence of microplastics may affect human health through bioaccumulation and transmission of toxic chemicals.
Opioid-induced constipation affects 40-60% of patients taking chronic opioid therapy. A new AGA guideline recommends starting with traditional laxatives as first-line agents, followed by PAMORA drugs if symptoms persist. These treatments aim to improve bowel symptoms without compromising pain relief.
The American Gastroenterological Association has launched a new initiative to foster opportunities for underrepresented minorities in gastroenterology research and career development. The program aims to provide training, mentoring, and leadership skills to promote diversity in the field.
A Mayo Clinic study found that specific gut bacteria, such as Phascolarctobacterium and Dialister, are associated with weight loss success and failure, respectively. The research suggests that individualized strategies may be needed to address the unique metabolic needs of each person.
A new study finds that video consultations between primary care physicians and specialists improve liver disease care and increase patient survival rates. Patients who participated in these consultations had a 54% higher survival rate compared to those without access to virtual consultations.
A study using oral-delayed release methylene blue during colonoscopy found a 56.3% detection rate for adenomas and carcinomas, nearly 9% higher than the standard of care. The tablet form reduces inconvenience and safety risks while improving adenoma detection rates.
A landmark study found that IBS patients who learned to control severe GI symptoms at home saw significant improvement, comparable to those treated with multiple clinic visits. The home-based behavioral treatment approach provided sustained relief for up to six months, overcoming a common barrier in rural healthcare.
The American Gastroenterological Association's new clinical guideline focuses on critical decisions made during initial management of acute pancreatitis. It recommends goal-directed fluid resuscitation, early oral feeding, and enteral versus parenteral nutrition to alter the course of disease and duration of hospitalization.
Boston University researcher Michelle T. Long has received a five-year, $1 million NIH grant to continue her research on non-alcoholic fatty liver disease (NAFLD). Her study will focus on the clinical and genetic traits associated with hepatic fibrosis in 3,500 participants.
Two cases of young children with severe esophageal injuries caused by swallowed lithium batteries from fidget spinners have been reported. The incidents highlight the potential danger of button batteries in children's toys, particularly those not specifically designed for kids.
Researchers have made breakthroughs in IBD treatment with the approval of a new antibiotic and the use of Janus kinase inhibitors. These advancements aim to improve outcomes for patients who currently lack effective treatment options.
Studies show that home infusions can decrease infusion burden for selected patients and are cost-effective. Telemedicine may also improve outcomes but increases healthcare utilization. Urgent care access and patient education also lead to improved clinical outcomes and satisfaction.
Research presented at the Crohn's & Colitis Congress provides guidance for physicians to enhance IBD patient care. Studies show that better management of anemia improves overall outcomes, while IBD patients need better understanding of CRC screening intervals.
The AGA FMT National Registry is the largest planned FMT study, tracking 4,000 patients for 10 years. The registry aims to provide a wealth of data on FMT's effectiveness and long-term effects, helping advance research and improve treatment outcomes.
A population-based study found a 22% reduction in stomach cancer risk among those aged 60 and over who received antibiotic-based treatment for H. pylori infection compared to the general population. The study suggests that treating this type of bacterial infection in older adults can help reduce their risk of developing gastric cancer.
A new AI-assisted endoscopic system has been shown to automatically identify colorectal adenomas during colonoscopy, demonstrating a sensitivity of 94% and specificity of 79%. The system enables real-time optical biopsy, allowing for the complete resection of adenomatous polyps and preventing unnecessary polypectomy.
A study of 13,864 participants found no convincing evidence linking PPI use to increased dementia risk. The research suggests that PPIs are safe for patients who require them for long-term treatment, and benefits may outweigh risks.
The task force ranked tests into three tiers according to the strength of the recommendation for average-risk people. Colonoscopy is highly sensitive for cancer and precancerous lesions, while fecal immunochemical testing (FIT) is non-invasive and lower-cost but must be repeated annually. The new guidelines also recommend starting scre...
A new study published in Cellular and Molecular Gastroenterology and Hepatology found that consuming unsaturated fat can lead to fatty liver disease, contrary to its previously touted health benefits. The research used mice fed diets supplemented with either saturated or unsaturated fat, revealing the latter can cause liver damage.
Researchers found that prebiotic fiber supplementation reduced annual projected body weight increase in overweight and obese children by nearly triple, compared to a placebo. The study also showed specific gut bacterial shifts with prebiotic intervention.
A recent study reveals that many children with inflammatory bowel disease (IBD) are not meeting the recommended daily intake of calcium and vitamin D. Experts warn that this can lead to poor bone health, development issues, and increased risk of permanent height deficits.
Researchers identified a new test to predict the severity of IBD in children based on faecal microbiota profiles. The study found that children with more extensive IBD had distinct gut microbiota profiles, including higher levels of Clostridiales and Proteobacteria.
A study presented at the ESPGHAN conference warns that young children on a vegan diet without proper medical and dietary advice may experience vitamin B12, calcium, zinc, and high-quality protein deficiencies. These deficiencies can lead to devastating health effects, including irreversible cognitive damage and death.
A study finds that gluten-free items have a significantly higher energy content and different nutritional composition compared to their gluten-containing counterparts. This could impact children's growth and increase the risk of childhood obesity.
A University at Buffalo study found that patient satisfaction among IBS patients is influenced by demographic, GI, and psychological factors beyond the quality of care. The researchers discovered that reassurance from gastroenterologists, rather than diagnostic tests, drives patient satisfaction in this population.
A new ambulatory monitoring device tracks gastric slow waves in patients with gastroparesis, enabling better understanding of the condition and its treatment. The device offers a window into stomach bioelectrical activity, revolutionizing digestive disease diagnosis and treatment.
Dr. Anil K. Rustgi has received the 2017 Julius Friedenwald Medal from the American Gastroenterological Association for his significant contributions to all aspects of gastroenterology, including research and clinical medicine. He is a leading expert in GI cancers and pre-cancerous changes.
The compilation presents state-of-the-art reviews on the pathogenesis, pathophysiology, and therapy of obesity, with a focus on the gastrointestinal tract. Key findings highlight the importance of diet composition, lifestyle interventions, and pharmacotherapy in weight management and metabolic health.
The American Gastroenterological Association recommends a tailored approach to PPI use for different conditions, weighing benefits against risks. Long-term PPI users should have their doses reevaluated regularly to minimize side effects.
The AGA has created an Obesity Practice Guide to guide and personalize innovative obesity care for safe and effective weight management. The program includes a framework focused on business operational issues related to the management of obese patients, published in Clinical Gastroenterology and Hepatology.
A research team developed ingestible prototypes that draw energy from gastric acid and provide power for nearly a week. They used zinc and copper as electrodes to harness energy from both the stomach and small intestine.
A new study by University of Florida researchers found that people seeking emergency treatment for food obstruction are 10 times more likely to do so during or after national holidays and sporting events. The study also identified turkey as the most common impacted food, followed by chicken and beef.
The new position paper provides recommendations on the timing and content of introducing complementary foods, as well as methods of feeding and specific dietary practices. It emphasizes the importance of ensuring adequate iron intake from complementary foods for all infants, especially those on vegetarian diets.
Professor J. Calvin Coffey reclassified the mesentery as a single, continuous structure connecting the intestine to the abdomen, leading to potential advances in surgeries and disease diagnosis. Further study of mesenteric science could result in less invasive procedures, faster recovery times, and lower costs.
A study published by the American Gastroenterological Association found that adults with inflammatory bowel disease (IBD) diagnosed in childhood have better educational levels and higher annual incomes compared to their healthy counterparts. This news may alleviate anxiety for parents of newly diagnosed patients, providing reassurance ...