The COBRE for Reproductive Health aims to develop research infrastructure for a center supporting interdisciplinary research in women's reproductive health. Four investigators will focus on understanding mechanisms of preeclampsia, gestational diabetes, and prematurity using pre-clinical models and computational approaches.
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The US Preventive Services Task Force found inadequate evidence on screening pelvic examinations for gynecologic conditions, including ovarian cancer and other benign conditions. The examination's accuracy, benefits, and potential harms were not well-established.
Researchers found that glucose supplementation shortens total labor duration by 76 minutes without increasing complication rates. This low-cost and safe intervention is recommended for women experiencing induced labor.
A new review highlights effective interventions for managing health complications from female genital mutilation, sparking further research on addressing the needs of millions affected worldwide. The World Health Organization's guidelines provide a crucial starting point, but more work remains to determine the most effective treatments.
A study published in American Journal of Obstetrics & Gynecology evaluated treatment options for pelvic organ prolapse, comparing surgery and pessary. The research found that women undergoing surgery experienced greater improvements in physical, social, emotional, and sexual functioning compared to those using a pessary.
Despite full standard investigation, the cause remains unknown in most stillbirth cases. The study highlights the need for further research to improve post mortem techniques to better detect a cause of death. New techniques may help support families and reduce the impact of identifying small babies as a risk factor.
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A new smartphone application was found to be an effective tool for teaching comprehensive sexual health to adolescent girls. The study, published in the Journal of Pediatric and Adolescent Gynecology, shows a significant increase in participants' knowledge and practical use of contraception after using the app.
A study published in the American Journal of Obstetrics and Gynecology found that nicotine patches and Zyban are effective in helping pregnant women quit smoking, with success rates of 80% and 60%, respectively. The use of these products also reduces the risk of premature birth and low birth weight.
A new study shows that removing fallopian tubes during hysterectomies can help prevent ovarian cancer without compromising surgical outcomes. The procedure has been widely adopted in Kaiser Permanente's Northern California system, with no increase in complications or length of stay.
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Researchers at MD Anderson Cancer Center have made significant breakthroughs in the treatment of endometrial and ovarian cancers. A Phase II trial combining everolimus, letrozole, and metformin shows a 67 percent clinical benefit rate for patients with recurrent endometrioid endometrial cancer. Additionally, hormonal maintenance therap...
A study from Northwestern University found that some FDA-approved high-risk medical devices used in obstetrics and gynecology were not effective in clinical trials. The authors recommend increasing the burden of proof required for device approval and relying on higher quality studies.
A study reveals that text messaging is an effective way to monitor postpartum women for life-threatening complications of preeclampsia. The remote blood pressure monitoring system allowed physicians to identify advanced cases and intervene before hospital readmission was necessary.
A study found that traumatic childhood experiences have a profound impact on the mental health of healthcare professionals, causing them to think more deeply about life's meaning. The findings highlight the need for adequate support for clinicians in the aftermath of traumatic childbirth.
The International Journal of Gynecology and Obstetrics identifies key factors associated with intimate partner violence, including infertility/subfertility as a risk factor in low- and middle-income countries. The research contributes to efforts to establish ways to identify individuals at risk and develop successful interventions.
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A study from Sahlgrenska Academy found that free gynecological pap test screenings did not increase participation among women in socioeconomically disadvantaged areas. Despite a low fee of SEK 11, the results showed only a slight difference in participation rates between those offered free screening and those who paid the usual fee.
A study published in the Journal of Obstetrics and Gynaecology Canada found that less invasive hysterectomies resulted in quicker recoveries, fewer complications, and cost savings for The Ottawa Hospital. The research showed a significant increase in minimally invasive surgeries from 40% to 74% between 2005 and 2012.
A recent study found that antenatal corticosteroids can significantly reduce the rate of neonatal respiratory complications in babies born between 34 and 36 weeks gestation. The research, published in the New England Journal of Medicine, involved approximately 2,800 women who received either two injections of betamethasone or placebo. ...
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A study published in Obstetrics & Gynecology found significant disparities in scholarly productivity between male and female gynecologic oncologists. Female doctors were less productive in lower academic ranks, but more productive later in their careers.
A recent study has uncovered 9 additional genetic mutations associated with an increased risk of ovarian cancer, bringing the total to 11. Researchers found that 18% of women with ovarian cancer carried these mutations.
A new study from Washington University School of Medicine found that chlorhexidine-alcohol is significantly more effective in preventing surgical-site infections after cesarean sections. The research, which included 1,147 patients, showed a nearly half reduction in infection rates compared to iodine-alcohol.
A study developed a simple risk scoring system to predict the likelihood of cesarean delivery in nulliparous women. The five-factor risk score accurately predicts an individual woman's risk of cesarean delivery, including advancing maternal age, short height, and increased fetal abdominal circumference.
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Researchers validated a two-protein test for predicting spontaneous preterm birth in asymptomatic women, identifying an optimal gestational age window and highly performing proteins. The study showed excellent performance of the novel classifier, with high accuracy rates for predicting preterm delivery before 35 weeks.
A new study found that out-of-hospital births in Oregon were associated with a higher risk of perinatal death, while in-hospital births were linked to increased cesarean deliveries and other obstetric interventions. However, the overall risk for perinatal death was low in all settings.
New research suggests that low-dose aspirin should be given prophylactically to all women at high risk of preeclampsia, which affects 3-7% of births in the US. The approach could reduce morbidity, save lives and lower healthcare costs.
Gynecologists argue the FDA's warning on power-morcellation is based on flawed data and may limit access to safe, effective treatment options for women. The study group suggests that better preoperative identification and new techniques could improve patient outcomes.
A national insurance database analysis revealed that 1 in 352 women had unsuspected cancer after undergoing minimally invasive gynecologic surgeries. The study highlights the need for safer alternatives to power morcellation to avoid worsening a woman's prognosis.
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The World Congress of the International Federation of Gynecology and Obstetrics has adopted recommendations from the Perinatology Research Branch at Wayne State University to prevent preterm birth. These guidelines include daily vaginal progesterone treatment for women with short cervices, which can reduce the risk by nearly half.
A new study found that laparoscopic hysterectomy without morcellation was the most effective procedure, while laparoscopic hysterectomy with power morcellation was associated with more intraoperative complications but fewer perioperative risks. The risk of cancer dissemination and mortality varied by age, with higher risks for older wo...
The International Federation of Gynecology and Obstetrics calls for increased efforts to prevent exposure to toxic chemicals, linked to reproductive issues such as miscarriage, stillbirth, and cancer. The group advocates for policies to protect patients and communities from involuntary chemical exposure.
Northwestern Medicine researchers aim to develop new treatments for uterine fibroids using novel targets and pathways. The NIH grant supports projects focused on progesterone effects, nuclear receptors, and AKT pathway modification.
Georgia Regents University is among 15 institutions receiving federal funding to train the next generation of physician-scientists in obstetrics and gynecology. The program will support junior faculty, residents, and fellows in research, enabling them to focus on research for at least 30 hours weekly.
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A study of nearly 60,000 women who received synthetic vaginal mesh slings for stress urinary incontinence found a low risk of needing second surgery for mesh removal or revision. High-volume surgeons performed fewer complications, and multiple mesh-based procedures increased the risk of complications.
A large international randomized clinical trial found that cervical pessary insertion did not reduce spontaneous preterm births or neonatal complications in women with twins. The study, published in the American Journal of Obstetrics and Gynecology, included 1,180 twin pregnancies and showed no significant differences between groups.
Research reveals that women outnumber men in 7 medical specialties, with the highest representation in pediatrics and obstetrics/gynecology. However, significant disparities remain in black and Hispanic trainee numbers compared to the U.S. population.
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A recent study reveals that nearly 1 in 3 counties in the US have limited access to specialty care for ovarian and cervical cancers, affecting 14.8 million women. The study also found that 15% of women may face barriers to care due to their referral network.
Research reveals that nearly a third of low-risk pregnancies experience unexpected complications requiring non-routine obstetric or neonatal care. The study analyzed data from over 10 million birth certificates and found that women without prenatal risk factors may still face unexpected complications during delivery or postpartum.
Women treated for gynecologic cancers experience decreased sexual activity, with younger and premenopausal women at higher risk. Counseling during treatment may help alleviate long-term effects on sexual health.
Dr. Gary Frishman's editorial in Journal of Minimally Invasive Gynecology suggests that second-look laparoscopy may not be the best approach due to its risks and high cost. The procedure, which involves a repeat surgery to check for adhesions after a previous treatment, is questioned by Dr. Frishman as a model for responsible healthcare.
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Elective tubal sterilization is readily available to women with private payment, but Medicaid beneficiaries face a 30-day wait. Experts argue that this violates healthcare justice and access to permanent contraception for low-income women. The policy restricts nearly half of annual deliveries paid by Medicaid.
A study of over 1,300 women service members and veterans found that fewer than a third sought post-assault health care, despite growing awareness and efforts to deter sexual crimes. Researchers identified embarrassment, confidentiality concerns, and adverse career impacts as key factors preventing servicewomen from seeking care.
The University of Michigan's 1000+ OBGYN Project has developed four new collections of high-quality educational materials to support obstetrician-gynecologist training in low-resource countries. These materials, made publicly available for free, cover topics such as abnormal uterine bleeding and postpartum care, and are intended to imp...
Experts recommend using ultrasound as the first line of imaging for patients with pelvic symptoms due to its cost-effectiveness and safety. Ultrasound has evolved to be an effective tool for evaluating gynecologic patients, providing accurate results without radiation exposure.
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Dr. Ayman Al-Hendy has received two top honors from the Society for Reproductive Investigation for his outstanding record of scientific investigation and promising research career. He is being recognized for his work on fibroids, uterine growths affecting up to 75% of women, which can complicate pregnancy and cause excessive bleeding.
A new study published in the American Journal of Obstetrics & Gynecology found that laparoscopic hysterectomy with morcellation is associated with fewer postoperative complications and improved quality of life compared to abdominal surgery. The study used decision-tree analysis to compare outcomes according to the probability of compli...
Portugal's cesarean section rates dropped by 10% between 2009 and 2014, with a 14% reduction in state-hospitals. This decrease is linked to improved information sharing and training among healthcare staff, as well as the inclusion of C-section rates in hospital funding criteria.
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A large-scale study found a 0.22% incidence of uterine sarcoma in women after hysterectomy, with most cases being unexpected endometrial cancer. Researchers emphasized the need to balance minimally-invasive procedures with cautious preoperative planning.
Researchers found hormonal IUDs and contraceptive implants to be highly effective one year beyond their approved duration of use, with no pregnancies reported in the implant group. The study aims to enroll a total of 800 women to determine if these methods are effective for up to three years beyond FDA-approved duration.
A study published in Menopause found a link between early menopause and chronic fatigue syndrome in women, with 66% of those with CFS having undergone at least one gynecologic surgery. Women with CFS reported excessive bleeding and used hormones for purposes other than contraception more frequently.
A recent study published in the Journal of Clinical Investigation identified hyaluronon as a critical substance made by the body that protects against premature births from infection. The findings suggest that HA plays a crucial role in epithelial barrier function and offers cervical protection against bacterial infections.
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A study of over 3,000 women in Michigan found that nearly 40% did not receive alternative treatment before their hysterectomy. Nearly two in five women under 40 had unsupportive pathology, suggesting that treatment guidelines are often not followed.
A study published in Obstetrics & Gynecology found that robotic-assisted surgery for benign ovarian surgery has more complications and is significantly more expensive than conventional laparoscopic surgery. The median total cost of robot-assisted oophorectomy was $7,426, compared to $4,922 for conventional laparoscopic oophorectomy.
The article presents a framework for future development of fetal interventions while minimizing maternal risk. Experts highlight the need to limit the number of fetal surgery centers due to high costs and rare conditions.
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Research finds young multiparous women and those living in remote areas are at greatest risk of unplanned deliveries, which may increase infant mortality. The study suggests that limited access to proper medical care contributes to the increased risk.
A new Dutch study finds that elective C-sections significantly reduce infant mortality in breech presentations, with a 10-fold increase in fetal mortality for vaginal deliveries. Researchers analyzed 58,320 term breech births and found that elective C-section rates increased from 24% to 60%, resulting in a decrease of infant mortality.
Dr. Surendra Sharma, a research scientist and professor at Women & Infants Hospital of Rhode Island, has received the Distinguished Service Award for advancing reproductive immunology research. His laboratory focuses on understanding premature birth and pregnancy complications.
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A Yale University study found a 50% drop in obstetric malpractice liability claims and payments after implementing patient safety measures, including standardized care and teamwork training. The hospital's efforts reduced liability claims by 95%, saving over $47 million.
A study published in Acta Obstetricia et Gynecologica Scandinavica found that iron supplements improved energy, physical function, and social function in women with heavy menstrual bleeding. After one year of treatment, anemic women showed significant increases in these areas compared to non-anemic women.
A clinical review published in JAMA explores the diagnosis and management of mixed urinary incontinence in women, a condition affecting 20-36% of women. High-quality evidence supports treating stress and urge urinary incontinences with surgery and medications respectively.
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A new study by UTMB researchers discovered that exposure to oxidative stress, triggered by cigarette smoke, leads to premature aging of the placenta. This can result in preterm birth, a condition affecting millions worldwide. The findings suggest alternative strategies may be needed to prevent preterm births beyond current interventions.
Women who received collaborative care for depression at an obstetrics and gynecology clinic showed significant reduction in symptoms, with more than half experiencing post-traumatic stress disorder as well. The approach, called Depression Attention for Women Now, improved patient engagement, treatment recommendations, and follow-up care.