Articles tagged with Immunization
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Researchers successfully created a synthetic horsepox vaccine that offers protection against the vaccinia virus, which is associated with serious side effects. Mice immunized with the chimeric HPXV developed similar levels of protective antibodies as those inoculated with VACV, but had less severe reactions.
A large-scale study involving over 3 million Danish and Swedish adult women found no association between HPV vaccination and serious chronic diseases. However, the vaccine may increase the risk of developing celiac disease, particularly in Denmark where the condition is underdiagnosed.
A mass immunization campaign against Japanese encephalitis in Nepal resulted in a 78% reduction in JE cases and prevented an estimated 3,011 cases. The vaccine also cut the rate of acute encephalitis syndrome by 59%.
A study found that vaccine-hesitant parents in California are finding physicians willing to grant medical exemptions, leading to a significant increase in MEs. The exemption percentage decreased overall, but counties with high past PBE use saw the largest increases in MEs.
The European Centre for Disease Prevention and Control (ECDC) has released a survey report on immunisation information systems, showing strong potential for e-health to increase vaccination coverage. Digital systems are being piloted across EU/EEA countries, including automated reminders that can identify under-vaccinated populations.
A new analysis suggests that the US Centers for Disease Control and Prevention's (CDC) recommendation against the inhaled flu vaccine may not be detrimental if it becomes effective. The study found that close surveillance will be needed to ensure the vaccine continues to do more good than harm.
Persistent stockouts and exposure to freezing temperatures are among problems in outdated vaccine supply chains, according to researchers. The challenges hinder the impact of vaccines on safeguarding people's health, with one in three countries experiencing at least one stockout of a vaccine for at least one month.
A clinical trial shows that Sanaria's PfSPZ Vaccine induces strain-transcending T cells and provides durable protection against both same and different malaria parasites. The 3-dose regimen offers long-lasting immunity, with 64% of subjects protected 19 weeks after the final dose.
The Ottawa Hospital's new comic book, 'Invasion of the Alien Zombies,' aims to educate elementary school students about the immune system and the importance of immunization in defending against illness. The comic uses a kid-centered approach, taking inspiration from Dr. Wilson's presentation to his son's science class.
A recent UBC study found significant variations in kindergarten vaccination rates across Metro Vancouver, with some areas having rates as low as 60%. The study used Vancouver Coastal Health data and analyzed the impact of location, school type, and other factors on vaccine coverage.
Researchers have developed a new approach to prevent gastrointestinal disease caused by Salmonella and other bacteria. The immunization targets a molecule that allows these microbes to scavenge iron, reducing growth and bacterial levels.
A University of Pittsburgh-developed program successfully increases vaccination rates in adult patients seen at primary care offices. Practices participating in the 4 Pillars Practice Transformation Program had nearly three times the increase in Tdap vaccine uptake compared to non-participating offices.
A Rochester Institute of Technology researcher is developing a comprehensive model for affordable vaccines in low-income countries through a three-year grant. The model aims to simulate a coordinated vaccine market that balances affordability with sustainability and profit.
Analysis of three types of Zika vaccines reveals they are effective at protecting rhesus monkeys from the virus. The vaccines induce strong antibody responses and provide complete protection against Zika when exposed to the virus.
The American Cancer Society has endorsed HPV vaccination recommendations from the CDC, recommending routine vaccination of all children at age 11 or 12. Vaccination is also recommended for females ages 13 to 26 and males aged 13 to 21 who have not been vaccinated previously or completed the 3-dose series.
Using drones to deliver vaccines in low- and middle-income countries could improve vaccination rates by up to 96% while producing significant cost savings. The technology has the potential to save $8.93 per dose and annual infrastructure costs of up to $60,000.
A University of Michigan-led study analyzing Google Trends data found a significant reduction in chickenpox searches following vaccination implementation in countries like Germany. The study demonstrates the effectiveness of immunization in reducing seasonal outbreaks and offers a novel way to track global childhood disease burdens.
A groundbreaking study released in The Lancet shows that a single injectable dose of inactivated polio vaccine (IPV) along with bivalent oral polio vaccine can protect up to 90% of children from polio. The research demonstrates faster and stronger protection compared to using the oral vaccine alone.
Researchers found that immunization with soil bacterium Mycobacterium vaccae promoted stress resilience and improved coping behaviors in mice. The treatment also prevented stress-induced colitis, a symptom of inflammatory bowel disease, by approximately 50 percent.
The study found significant improvements in up-to-date vaccination rates, with a 7% increase from 75% to 82%. Over-immunization for adolescents also decreased significantly. The data exchange allowed clinicians to easily access patient immunization information, reducing the likelihood of unnecessary vaccinations.
Research led by the University of Pittsburgh School of Medicine found that state laws mandating influenza immunization for health care workers increased their vaccination rates from 22.5% to 50.9% between 2000 and 2011. The study suggests that stronger laws, including mandates and education, lead to higher vaccination rates.
Researchers at Arizona State University have developed a simpler method to produce antibodies against a range of infectious agents using DNA-based genetic immunization. The technique successfully expressed membrane proteins in mice and induced the animals to produce critical antibodies to bacterial and viral targets.
Global experts celebrate a major public health achievement with the introduction of MenAfriVac®, a vaccine designed for Africa that has nearly eliminated serogroup A meningococcal disease. Over 235 million children and young adults have been immunized, reducing cases from 250,000 in 1996 to just 80 in 2015.
A new study from Johns Hopkins Bloomberg School of Public Health found that vaccinations in 94 low- and middle-income countries could save up to $44 for every dollar spent. The study estimated a total cost of immunization programs at $34 billion, with averted costs of illness totaling $586 billion.
Researchers have developed a new vaccine candidate that significantly reduces the virus load in infected camels, offering a promising method to prevent human infections. The vaccine also provides dual activity, protecting camels from another disease similar to smallpox.
A vaccine developed for African meningitis A has led to the control and near elimination of deadly disease in 26 countries. However, scientists warn that unless countries maintain high levels of protection through routine immunization schedules, the disease could rebound in 15 years.
A recent study by the CDC and University of Georgia found that 75% of first-time expectant mothers planned to follow the recommended childhood immunization schedule. Most undecided mothers had low levels of confidence in vaccines, suggesting targeted outreach may be needed.
A patient with an immune deficiency has shed large amounts of live polio virus in their stool for over 20 years, posing a risk to global polio eradication. The highly mutated strain has acquired mutations that reverse the attenuating features of the vaccine strain, making it more difficult to neutralize.
A new study from the University of Michigan Health System found that electronic prompts and reminders resulted in significant increases in Tdap vaccine uptake among patients aged 11-64. The system improved vaccine rates by 76% for adults and 85% for adolescents, compared to 59% in similar-aged groups without automated prompts.
The Alliance for Aging Research released a white paper highlighting the factors driving low vaccination rates among seniors and offering recommendations for improvement. Vaccination rates are lower than target levels set by Healthy People 2020, resulting in significant health issues and deaths among older adults.
Faith-based organisations have played critical roles in delivering education, health, and social services, particularly in hard-to-reach areas. Religious leaders provide a much-needed complement to public health messages, inspiring congregations to adopt healthy behaviours.
A new global survey finds varying levels of vaccine hesitancy worldwide, with the UK and Nigeria showing high rates. Strategies to overcome challenges are crucial, as public confidence can severely undermine immunization programs.
A new study found that a centralized notification system improved immunization rates by reaching 87% of eligible children and increasing documentation rates. The system was more cost-effective than practice-based approaches, with substantial cost savings expected from a societal perspective.
A study found that an oral supplement containing arginine, zinc, and antioxidants improves healing of mild to severe pressure ulcers in malnourished patients. Meanwhile, a survey suggests that pain and other alarming symptoms in the last year of life have increased from 1998 to 2010. The Centers for Disease Control and Prevention's ACI...
Researchers used spatial analysis software to identify clusters of underimmunization and vaccine refusal among Kaiser Permanente members in Northern California. Underimmunization ranged from 18% to 23% within clusters, compared to 11% outside clusters, highlighting areas with high vaccine refusal rates.
Vaccines targeting HIV can backfire and lead to increased infection rates if they activate too many viral target cells. A recent primate model study found that higher levels of activated CD4+ T cells in mucosal tissues were associated with an increased risk of infection.
Researchers found that wearing a hijab buffers against negative body image among British Muslim women, reducing reliance on media beauty standards and emphasis on appearance. The study suggests the hijab helps some women reject prescriptive beauty ideals.
Researchers have successfully mutated the powerful anti-HIV bNAb called VRC01 to make it last longer in blood and collect in rectal mucosal tissue, potentially blocking HIV transmission. A low-dose infusion of mutated VRC01 also protected monkeys against SHIV infection more effectively than unmutated VRC01.
Pediarix is the most cost-effective combination vaccine, but Pentacel's sales are higher due to overlooked factors. Health care providers often overlook extra immunizations required for certain vaccines.
A study found a significant reduction in HPV types 16 and 18 infections among young women in England after the introduction of the HPV vaccination program. The prevalence dropped from 1 in 5 to 1 in 15 among those aged 16-18, with the lowest rates among vaccinated individuals.
A study found that changing hospital orders increased pertussis immunization rates by 69% among new mothers, providing protection for themselves and their newborns. Implementing a standing order led to the largest increase in vaccinations, raising the rate from zero to 69%.
Between 2009-2012, 18 states introduced 36 bills modifying school immunization mandates, with the majority expanding exemptions. Most bills with administrative requirements restricted exemptions, but none were passed. The study highlights ongoing challenges in maintaining high immunization coverage.
The American College of Physicians and the Centers for Disease Control and Prevention have released an updated adult immunization schedule for 2014. Key changes include the removal of health care worker vaccination as an indication and updated recommendations for certain adults at increased risk for Haemophilus influenza type b (Hib) i...
Scientists have identified a potential treatment mechanism for the EV71 virus, which causes severe brain swelling and paralysis in children. The discovery was made by creating antibodies that can neutralize the virus by inducing genome release, rendering it non-infectious.
A Kaiser Permanente study found that administering the first measles-containing vaccine between 12-15 months old is associated with a lower risk of fever and seizures compared to receiving it at 16-23 months. The study analyzed data from over 840,000 children who received a measles-containing vaccine between 2001 and 2011.
The articles highlight the need for a shift away from leader-centric approaches and towards building trust with communities, prioritizing routine health services, and supporting frontline female health workers. This includes increasing investment and time to achieve stronger health systems and universal immunization in these countries.
A parental survey to measure vaccine hesitancy was linked to children's underimmunization rates. Parents with higher survey scores were more likely to have underimmunized children, highlighting the potential for such surveys as a predictive tool.
The nationwide HBV immunization program, launched in 1984, successfully lowered chronic HBV carrier prevalence, HCC incidence, and mortality of infant fulminant hepatitis in vaccinated birth cohorts. Long-term high-coverage immunization was associated with increased herd immunity and lower IFH mortality rates.
A study by Columbia Nursing researchers found that automated reporting of immunization data through EHRs increased knowledge about individuals and communities, allowing medical and public health officials to make informed decisions. This led to reduced lag times, improved documentation, and enhanced efficiency in vaccine tracking.
The Sabin Vaccine Institute has launched the International Association of Immunization Managers (IAIM) to help drive national, regional, and international immunization goals. IAIM aims to equip immunization managers with tools and a professional network to advance their programs.
A collaborative study using Vaccine Safety Datalink data analyzed four years of data and found that background mortality rates are lower in vaccinated populations than the general US population. These rates can be used to identify unusual increases in deaths following vaccination.
A new global surveillance tool detects and monitors public concerns about vaccines, allowing for swift responses to prevent low vaccine uptake and disease outbreaks. The tool analyzes reports from 144 countries, identifying key themes and prioritizing action to promote immunisation.
A new study published in Pediatrics found that flu vaccines are safe for children with inflammatory bowel disease (IBD), without increasing adverse events. The research suggests that receiving the influenza vaccine may even protect against IBD flare-ups and doctor visits.
African experts argue that immunization systems are failing due to issues with vaccine supply, financing, and sustainability. The authors call for strengthened programs to address regional and country-specific problems and develop precise strategies to overcome challenges.
A recent study by Mayo Clinic found that over 2 in 5 parents are hesitant to vaccinate their teenage daughters against human papillomavirus (HPV) due to potential side effects. The vaccine is recommended for teens to prevent cervical cancer and genital cancers, with the majority of experts agreeing on its necessity.
A Kaiser Permanente study found that nearly half of children under 2 years old did not receive all recommended vaccinations. Children who missed scheduled vaccines were more likely to be admitted to hospitals and have fewer doctor visits than those vaccinated on time.
Researchers suggest that vaccinating around 46% of Haitians could arrest the spread of cholera. Using mathematical models to target immunization campaigns can help control recurrent outbreaks and slow transmission rates.
A Kaiser Permanente study found that Tdap vaccination is as safe as Td vaccination for adults 65 and older, with no increased risk of injection site reactions. The study provides empirical evidence supporting the use of Tdap in reducing pertussis infections among older adults.
Researchers report progress in Pakistan's efforts to eradicate polio, with the potential elimination of one type of wild poliovirus. However, vaccine refusals remain a major challenge, driven by false rumors and misinformation. In Nigeria, a surge in cases threatens to re-infect countries that have already been cleared of polio.
Two studies estimate the cost of delivering HPV vaccines to girls in Tanzania, finding costs substantially higher than existing infant immunization schedules. However, integration with existing health systems may improve affordability and effectiveness of HPV vaccination programs, especially in low- and middle-income countries.