Research on the medical care of infants and children. Covers pediatric emergencies, blood-pressure thresholds, infectious disease, kidney injury, and developmental health.
A study found that non-driving-related license suspensions are given to over 90% of drivers in New Jersey, affecting low-income neighborhoods and communities of color. These suspensions disproportionately limit access to employment and healthcare, with failure to pay fines being the most common reason.
A Dartmouth-led study reveals that pediatric mental health boarding is a prevalent and understudied issue, affecting 40,000 to 66,000 youth admitted to hospitals each year. The research team found key risk factors for children, including age, suicidal thoughts, and seasonal hospital visits.
Researchers at Children's Hospital of Philadelphia developed a new study using a handheld device to measure pupil response to light, revealing clear differences between concussed and healthy adolescent athletes. The study found significant variations in pupil diameter, constriction, and dilation velocity among concussed athletes.
The National Comprehensive Cancer Network has published a new patient and caregiver resource focused on childhood cancer type, pediatric acute lymphoblastic leukemia. The guidelines provide easy-to-understand information on treatment options, including charts and images, to help patients and caregivers make informed decisions.
Researchers at Children's Hospital of Philadelphia found that cardiac involvement in multisystem inflammatory syndrome in children (MIS-C) is associated with myocardial injury, differing from Kawasaki disease. Long-term effects on cardiac function and sports participation require further study.
A randomised controlled study found that computerised training can support preterm children's academic success, particularly in math and attention skills. The study tested two learning apps, Xtramath and Cogmed, on 65 first graders born preterm.
A study found that children's immune responses are better equipped to fight COVID-19 than adults. Children possess higher levels of certain cytokines associated with the innate immune response, which helps protect them from developing severe disease.
The Texas Heart Institute will develop the first fully implantable circulatory support device for pediatric patients, aiming to stop advanced heart failure progression. Led by Dr. O.H. Frazier, the team will conduct preclinical studies and collaborate with international consultants.
A new study suggests that children and adolescents diagnosed with white-coat hypertension may progress to sustained hypertension if not monitored regularly. White-coat hypertension is a condition where blood pressure increases only in a doctor's office, but its impact on kids is unclear.
Researchers found that standard CDS systems are ineffective in reducing antibiotic prescriptions in EDs. The study suggests tailoring CDS systems to the ED environment and provider needs can help reduce unnecessary antibiotic use.
A study of 141 pediatric patients transferred to an adult rheumatology clinic found that continued insurance coverage and referral from a pediatric rheumatologist reduced delays in attending adult visits. Pediatric patients with connective tissue diseases or Black race were particularly vulnerable to unscheduled hospitalizations.
A 14-year-old boy's mysterious symptoms led to a rare diagnosis of multisystem inflammatory syndrome in children (MIS-C) caused by COVID-19. A new clinical pathway has been developed to quickly identify and treat cases, saving lives with timely information-sharing.
The special journal issue features Nemours pediatric cardiologists' expertise on echocardiography and other imaging techniques used in children with cardiovascular disease. The articles highlight best practices for screening, diagnosing, and managing congenital heart disease to improve patient outcomes.
Researchers at Children's Hospital of Philadelphia found convalescent plasma to be a safe treatment option for children with life-threatening COVID-19 cases. The study suggests that convalescent plasma may provide the greatest benefit for early-stage patients who have not yet generated endogenous antibodies.
Researchers aim to enroll patients aged 6-17 with moderate to severe PANS and evaluate the effectiveness of PANZYGA versus placebo in reducing symptoms. The study will also assess sustainability and functional impairment associated with PANS treatment.
A recent study published in Journal of Pediatrics found that COVID-19 patients, especially children under 16 years old, can have both the virus and antibodies in their system simultaneously. The study suggests that these children still pose a risk of transmitting the virus even if they have developed antibodies.
A unique strain of Shiga-toxin E. coli (STEC) has been identified through genomic analysis, revealing its genetic makeup and potential for severe disease. The study's findings may contribute to the development of vaccines against emerging STEC pathogens.
A recent study by McMaster University found that only 28% of new Canadian drugs have clear pediatric data, and many critical diseases lack approved treatments. This absence perpetuates 'off-label' drug use, which can lead to inadequate treatment or increased side effects.
A new study found that young adults who used legal performance-enhancing substances were more likely to report problematic alcohol use and drinking-related risk behaviors seven years later. The study highlights the need for government oversight and regulation of these substances, which can lead to health problems and worsen mental health.
A new study models the estimated time to clear surgeries postponed in Ontario due to COVID-19, predicting an 84-week backlog. The target is 717 surgeries per week, with a focus on prioritizing critical procedures.
Research suggests children with no COVID-19 symptoms may still shed virus for weeks, making them potential key vectors. The study's findings also highlight the importance of understanding viral shedding in asymptomatic patients and its impact on herd immunity.
A new study found that teen drivers and older adults are more likely to drive vehicles with fewer critical safety characteristics, putting them at higher risk of injury. Drivers from lower-income neighborhoods were also less likely to drive newer, safer cars.
A retrospective study from the University of Missouri-Columbia found that vertebral body tethering (VBT) is a promising alternative to posterior spinal fusion (PSF) for treating scoliosis in pediatric patients with growth remaining. VBT yields a high success rate, preserving mobility and correcting curves in 74% of patients.
A study published in Pediatrics found that artificial intelligence models can accurately identify well-appearing infants with fever who are at low risk for a serious bacterial infection. This could lead to a significant reduction in unnecessary invasive procedures, antibiotics, and hospitalizations.
A small pilot study found that treating gout with probenecid improves heart function and exercise performance in children with a specific type of heart defect. The study suggests that repurposing this medicine to treat heart problems in these patients may be effective without adverse effects.
A new study published in Pediatrics reports positive safety and early outcome data from 21 children with spinal muscular atrophy treated with gene therapy. The treatment, onasemnogene abeparvovec-xioi, is shown to be effective through age 2 years with proper screening and monitoring, but requires closer attention for potential liver is...
A new UCSF study found that the prevalence of SARS-CoV-2 among asymptomatic children mirrors the number of confirmed cases in the general population. Researchers developed an equation to estimate the number of infected students in a classroom based on local data, revealing risks ranging from 11% to 79%.
Pediatric outpatient visits for notifiable infectious diseases declined during the COVID-19 outbreak in Beijing. The study found a significant reduction in these visits due to strict public health measures, suggesting that other types of hospital visits were also affected.
A comprehensive pediatric study shows children can carry high levels of the virus and spread infection, contradicting previous assumptions. The study's findings have implications for reopening schools and daycare centers, highlighting the need for increased precautions to keep kids, teachers, and staff safe.
A recent survey of pediatricians found significant variability in recommendations for solid food introduction, leading experts to question the relevance of current guidelines. The long waiting period may delay peanut introduction and limit food diversity, which can decrease the development of allergic diseases in infants.
A study found that 11.4% of second-opinion radiology reports were ignored by clinicians, with sonography and pediatrics having the highest rates. The cost of these ignored reports could be substantial, estimated at €53,700 or approximately $63,427.
The American Academy of Pediatrics provides guidelines for safe K-12 school reentry, focusing on infection control measures, social distancing, and mental health support. Effective operational planning is crucial to minimize risks and ensure a smooth transition back to in-person learning.
A team of researchers linked genetic information with electronic medical records to identify the impact of genetic epilepsies on affected children's lives. They found associations between specific genes and clinical features, such as seizures and intellectual disability.
A new pediatric study finds significantly higher COVID-19 infection rates among minority and socioeconomically disadvantaged children in the US. The study mirrors disparities found in adult populations across the country.
Pediatric infectious disease experts provide recommendations on return to school for SOT children, considering factors like clinical risk, community transmission, and infection prevention measures. The majority of SOT recipients are expected to outweigh the risks and benefit from attending school.
Cerebral palsy affects children's gross motor skills and muscles, leading to stiffening and weakness. Rehabilitation interventions improve quality of life for individuals with CP, including botulinum toxin injections and robot-assisted gait training.
Dr. Emmanuel Katsanis is studying a new chemotherapy treatment for patients with blood-related cancers who undergo a specific type of bone marrow transplant procedure. The treatment, known as haploidentical BMT, has shown promising results in improving survival rates and reducing post-transplant complications.
Drs. Sallie Permar and Stephen Patrick have been awarded the fifth annual Gale and Ira Drukier Prize in Children's Health Research for their groundbreaking research on neonatal viral infections and opioid epidemic's impact on pregnant women and infants. Their work has informed national policy and offers hope to untold expectant mothers.
A recent study from Ann & Robert H. Lurie Children's Hospital of Chicago found that young children with mild to moderate COVID-19 have higher viral loads than older age groups, suggesting they can transmit the virus just as easily. This finding has significant public health implications for discussions on reopening schools and daycare.
Surgeons from Children's Hospital of Philadelphia propose categorizing surgeries into four classes based on urgency and risk. Class-1 emergency surgeries must happen right away, while Class-4 elective surgeries should occur once the pandemic has reached its low point.
Researchers developed a computational algorithm to analyze noncoding mutations across five major pediatric cancers. The study identified 1,137 structural variants affecting over 2,000 genes, highlighting their potential as cancer-causing mutations.
A new study shows that IUDs significantly reduce menstrual symptoms in adolescents with disabilities, including heavy bleeding and cramping. The research found that 65% of young women reported less bleeding and 95% kept their IUD after one year.
Researchers at Loyola University Medical Center identified common symptoms in pediatric acoustic neuroma patients, including hearing loss and vertigo. They also found that residual tumors in pediatric patients had a higher rate of regrowth than those in adults.
The National Pediatric Rehabilitation Resource Center aims to promote clinical trials research in pediatric rehabilitation. The center will fund up to $150,000 per year for pilot studies and offer educational resources to support the growth of the field.
Researchers found that being African American strongly associated with higher risk of postoperative complications and mortality among apparently healthy children. African American children had 27% greater odds of developing postoperative complications and 3.43 times higher odds of dying within 30 days after surgery compared to white peers
A study published in JAMA Network Open found that only 30% of US pediatricians fully implement recommended practices for preventing peanut allergy, with common barriers including lack of clinic time and parental fear. The 2017 guidelines aim to introduce peanut-containing foods at 4-6 months to reduce prevalence.
A new study published in Pediatrics finds that a community development initiative in Columbus, Ohio's Southern Orchards neighborhood reduced emergency department visits by 20.8% and inpatient admissions by 12.7%. The improvement is attributed to housing improvements and other interventions.
A study of 212 newborns found that higher proportions of Bacteroidetes bacteria in meconium were associated with later obesity. The infant's microbiome before birth may play a role in their weight status.
A collaborative study has identified NPHS1 as a disease-susceptibility gene for steroid-sensitive nephrotic syndrome in children. Variants in this region of chromosome 19 were found to be associated with the disease, and their impact on nephrin mRNA expression was confirmed.
A new study found that low-income families receiving SNAP benefits later in the month experience fewer emergency room visits for childhood injuries, likely due to better meal planning and food security. The researchers suggest that supporting federal food assistance programs like SNAP can help reduce childhood injuries and morbidity.
A study published in the Journal of the American Heart Association found that even minor heart defects can lead to chronic diseases, such as arrhythmia and heart failure, in adulthood. Adults who underwent congenital heart surgery during childhood are more likely to experience lower levels of education and employment rates.
A large systematic review of children with COVID-19 from 26 countries found that most cases had mild symptoms, with 19% having no symptoms. Laboratory findings showed abnormal inflammatory markers, but severe cases were rare, with only seven deaths reported.
A new case series published in Radiology examines the spectrum of imaging findings in children with Multisystem Inflammatory Syndrome in Children (MIS-C) associated with prior exposure or infection to SARS-CoV-2. The study identified a pattern of imaging findings including airway inflammation and pulmonary edema.
Scientists have discovered a common TP53-R337H variant among people of Brazilian descent that increases cancer risk when combined with an inherited XAF1 mutation. The study found individuals with both mutations are at a greater risk of cancer, highlighting the importance of genetic screening and public health approaches.
A new study by Boston Children's Hospital found that reducing resident physicians' work hours can worsen patient safety if caseloads are too high. The study discovered that residents who cared for more patients experienced a higher rate of medical errors, highlighting the need for better staffing standards.
NYU Dentistry's Bridging the Gap program aims to expand dental workforce with skills and commitment to patients with disabilities. The five-year grant will integrate training into NYU's Advanced Education Program in Pediatric Dentistry, creating new curricula for general dentists and dental hygienists.
Dr. Gosain's lab aims to establish a causative relationship between dysbiosis and Hirschsprung-associated enterocolitis, identifying key drivers of the disease and potential therapeutic targets.
Researchers at the University of Houston have identified three different stem cell types in Crohn's biopsies, with two variants contributing to inflammation and fibrosis. The team is developing new drug therapies to selectively destroy these rogue cells and create new treatments for pediatric and adult Crohn's disease.
According to a new Stanford-led study, California's most vulnerable premature babies are now healthier when they go home from the hospital. The proportion of infants who survived without major complications increased from 62% to 67%, while those with major complications had fewer of them.
A Phase 2 study led by UB pediatric endocrinologist Teresa Quattrin shows that golimumab, an anti-TNF therapy, preserved beta-cell function and reduced injected insulin required in children and young adults with newly diagnosed Type 1 diabetes. The study demonstrated a higher C-peptide level in patients treated with golimumab compared ...