Articles tagged with Vitamin B12
A study of 5,442 female health professionals found that combined folic acid, vitamin B6, and vitamin B12 supplements did not reduce the risk of colorectal adenomas. No association was seen between supplement intake and cancer risk despite previous observational studies suggesting potential protective effects.
A new transport protein, ABCD4, has been identified as responsible for the transfer of vitamin B12 from lysosomes into cells. This discovery provides evidence for another cause of hereditary vitamin B12 deficiency and enables diagnosis and treatment.
A team of scientists identified a gene that is vital to the transport of vitamin into cells, leading to early diagnosis and potential treatment for a rare genetic disorder. The discovery sheds light on how vitamin B12 functions in the body.
A pilot study found that adding vitamin B12 to standard hepatitis C virus treatment significantly boosts the body's ability to keep the virus at bay, especially in patients with genotype 1 HCV or high viral loads. The treatment strengthened the rate of sustained viral response by 34%.
Researchers from University of Michigan and MIT create 3-D images of vitamin B12 and its partner molecules twisting and contorting during a crucial reaction called methyltransfer. This process is vital for human health and has potential implications for alternative renewable energy sources.
Researchers at Rush University Medical Center found a link between low vitamin B12 levels and reduced brain volumes in older adults. Cognitive tests revealed lower scores among participants with high vitamin B12 deficiency markers.
A study found that low vitamin B12 levels may lead to brain cell loss and cognitive decline in older people. Vitamin B12 deficiency was associated with lower scores on cognitive tests and smaller total brain volume.
Researchers have developed a new, non-invasive breath test to detect vitamin B12 deficiency, a growing public health problem. The test measures the amount of carbon dioxide exhaled after administering propionate, which is broken down by vitamin B12 in the body.
A review of vegetarianism's biochemistry suggests that vegans may be at higher risk for blood clots and atherosclerosis due to low levels of essential nutrients. Increasing dietary omega-3 fatty acids and vitamin B12 can help mitigate these risks, particularly through sources like salmon, walnuts, and fortified milk.
A review of vegetarianism's biochemistry finds vegans at elevated risk for blood clots and atherosclerosis. Key nutrients like omega-3 fatty acids and vitamin B12 can mitigate this risk with dietary supplements or fortified foods.
A seven-year study found that higher levels of vitamin B12 reduced the risk of Alzheimer's disease by two percent, while low homocysteine levels were associated with a 16% increased risk. The study suggests that vitamin B12 may be used as a supplement to help protect memory.
A study of 12,064 survivors of heart attack found that folic acid and vitamin B12 supplementation did not lower the risk of heart attack, coronary death, or stroke. The researchers also found that folic acid supplementation did not increase the risk of cancer.
A Norwegian study found that folic acid and vitamin B12 treatment was associated with a 21% increased risk of cancer diagnosis and a 38% increased risk of cancer-related death in patients with ischemic heart disease. The treatment also showed an increased risk of lung cancer incidence.
Researchers found a significant link between osteoporosis and bronchiectasis, as well as a new formula to calculate 'lung age' in smokers that may help with quitting. Low muscle mass and high body fat are also associated with poor lung function in the elderly. Additionally, vitamin B12 deficiency may be linked to chronic cough.
Research found that vitamin B6, folate, and vitamin B12 supplements effectively lower plasma homocysteine levels in patients with celiac disease. The study also discovered a protective role of B vitamins against the negative effects of villous atrophy on homocysteine levels.
Women with low vitamin B12 levels have a 5 times increased risk of having a child with a neural tube defect compared to those with high levels. Vegans and vegetarians are at higher risk due to limited food sources, while intestinal disorders can also lead to deficiencies.
A new study suggests low levels of vitamin B12 may increase neural tube defects risk. Doctors agree pregnant women can thrive on well-planned vegan diets, offering nutritional benefits like lower saturated fat and higher fiber.
Researchers at Ben-Gurion University of the Negev found that a nightly dose of vitamin B12 significantly reduces Recurrent Aphthous Stomatitis (RAS) symptoms, including pain, ulcers, and outbreaks. The treatment resulted in a 74% remission rate among patients taking vitamin B12 compared to 32% for those receiving a placebo.
Researchers at McGill University and the MUHC have identified a gene crucial for vitamin B12 metabolism, shedding light on a rare genetic disorder. The discovery may lead to earlier diagnosis and treatment options for patients with cblF combined homocystinuria and methylmalonic aciduria.
A study found that daily folic acid and B vitamin supplements had no impact on cancer risk in high-risk women. The results suggest a lack of benefit for total invasive cancer and breast cancer, with age modifying the effect.
Researchers at Harvard School of Public Health have discovered a common genetic influence on vitamin B12 levels in the blood, suggesting a new way to approach the biological connections between an important biochemical variable and deficiency-related diseases. The study found that a gene variant associated with higher B12 levels may pr...
A study found that people with higher vitamin B12 levels were six times less likely to experience brain shrinkage compared to those with lower levels. Researchers suggest adjusting diets to consume more vitamin B12 may help prevent brain shrinkage and save memory.
A large clinical trial found that B vitamin supplementation did not reduce death or cardiovascular events in patients with coronary artery disease. The study, which involved over 3,000 participants, also showed a numerically lower incidence of stroke but higher incidence of cancer in the groups receiving folic acid.
A new oral formulation of vitamin B12 has shown promise in improving absorption rates without the need for invasive injections. The eligen technology has been tested in animal studies and is currently being conducted in human trials.
Scientists identified the MMADHC gene responsible for a rare genetic disorder, isolated and combined homocystinuria and methylmalonic aciduria. The research provides clues to how vitamin B12 works in the body and offers earlier diagnosis and treatment options for the serious disease.
Researchers found that high blood folate levels can increase homocysteine and methylmalonic acid in individuals with vitamin B12 deficiency, worsening symptoms. This study suggests that excessive folate may compromise the body's ability to use vitamin B12 effectively.
Researchers have developed a new drug called nitrosyl-cobinamide, a direct NO-releasing agent that could potentially treat hypertension and heart disease. The compound binds tightly to nitric oxide, forming a reversible NO donor, which may offer a safer alternative to existing treatments.
A new study from Tufts University found that high folate status and adequate vitamin B12 levels are associated with better cognitive function in seniors. Low vitamin B12 status was linked to increased cognitive impairment, while high serum folate was more detrimental when combined with low vitamin B12.
Researchers at UC Davis and Lawrence Livermore National Laboratory have developed a new test that can diagnose vitamin B12 absorption problems with a single drop of blood. This simple test could help identify patients at risk for dementia and anemia, allowing for early treatment and prevention of permanent damage. The breakthrough uses...
Researchers found that algae need vitamin B12 from bacteria due to an alternative metabolic process. This discovery highlights the importance of symbiotic relationships in maintaining ecosystem balance, with implications for global health and biodiversity.
A team of scientists has identified the responsible gene, MMACHC, for a rare and devastating genetic disease. The discovery enables the development of early diagnosis and carrier assessment tests, improving the lives of those afflicted with the disease.
Researchers found that vitamin B12 deficiency was common among patients referred to vascular disease prevention clinics. Creatinine levels were also found to be a strong predictor of homocysteine levels, similar to vitamin B12 levels.
Researchers found that patients given folic acid and vitamin B12 had a 38% decrease in plasma homocysteine levels, while the placebo group experienced a 31% increase. This combination therapy prevented hip fractures in stroke patients despite frequent falls, attributed to osteoporosis.
Researchers at the Friedman School of Nutrition Science and Policy at Tufts University have identified two variants in the perilipin gene associated with increased obesity risk in white women. Vitamin B12 deficiency has also been linked to lower bone mineral density, increasing the risk of osteoporosis.
Research findings suggest that a balanced diet prior to pregnancy can reduce the chance of spina bifida. Myo-inositol, zinc, and vitamin B12 supplements may also be beneficial in preventing the condition, although further research is needed to confirm this.
Researchers discovered that Nembutal suppresses colon cancer metastasis and improves post-radiation brain function. Additionally, erythropoietin was found to protect cognitive function after whole brain irradiation, while a new vitamin B12 molecule targets tumor cells.
Researchers found that elderly women with low vitamin B-12 levels experience rapid hip bone loss, a risk factor for fractures. Simple dietary supplements or multivitamins may help slow bone loss rates.
Researchers found a positive association between high vitamin B12 levels and effective treatment of major depressive disorder. Patients with higher vitamin B12 concentrations responded better to treatment, even when other factors were controlled for.
A Texas chemist has won a national award for his work on vitamin B12, a natural product he has worked with for about 30 years. He is now working on recreating the pathway for taxol, an anti-cancer drug derived from yew trees.
Researchers have identified two genes responsible for defects in vitamin B12 metabolism, which can lead to accumulation of methylmalonic acid. This breakthrough could enable DNA testing for carriers and early prenatal diagnosis, providing hope for families affected by the disease.
Researchers have identified organosulfur compounds, such as ADT, as effective in preventing lung cancer progression. Vitamin B12 analogues also showed promise in targeting chemotherapy drugs to tumor cells, while aminopeptidase inhibitors may help restore apoptosis in leukemia cells
A study published in the American Journal of Clinical Nutrition found that high levels of homocysteine correlate with lower cognitive test scores and decreased cognitive function in the elderly. Higher plasma concentrations of folate and B-12 were associated with improved cognitive performance.
Researchers found that supplementing with both folic acid and vitamin B12 can significantly lower homocysteine concentrations. This suggests that a dual-fortification policy could be more effective in reducing the risk of cardiovascular disease. The study's findings have implications for food fortification policies worldwide.
Researchers from UCSF found that folic acid and vitamin B12 supplements can lower homocysteine levels by 25% and 7% respectively, resulting in a 8-13% decrease in heart disease rates and deaths. The study estimates that adding these supplements to daily grains could save $24 billion over 10 years.
A 1996 study found that nearly half of Asian Indian participants had low vitamin B-12 levels, with 52% showing metabolic indications of deficiency. The study suggests genetic adaptations and gastrointestinal infections may contribute to the high prevalence of vitamin B-12 deficiency in this population.
A recent study found that women with impaired hearing had lower blood levels of vitamin B-12 and folate compared to those with normal hearing. The researchers suggest that dietary recommendations aimed at influencing the course of age-related hearing loss may be possible, but more advanced studies are needed.