Researchers at MD Anderson Cancer Center have identified a small molecule compound that restores physiological levels of telomerase reverse transcriptase (TERT), reducing cellular senescence and tissue inflammation. TERT restoration also spurred new neuron formation with improved memory and enhanced neuromuscular function.
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A new model developed by researchers at the University of São Paulo combines physical parameters and machine learning to predict storm tides. The model uses physics-informed machine learning, which harmonizes physical models with measured data to produce more precise forecasts.
Researchers at Delft University of Technology use drone racing to test neural-network-based AI control systems planned for next-generation space missions. The goal is to achieve optimal onboard operations by continuously replanning trajectories, reducing resource consumption and boosting mission autonomy.
This study reveals that thalamocortical connectivity plays a vital role in the formation of functional brain networks. The researchers used advanced neuroimaging techniques and computational models to map changes in thalamocortical connectivity across different age groups, from infancy to adulthood.
A team of researchers has made a breakthrough discovery about the mysterious condition known as 'happy hypoxia,' which affects some COVID-19 patients despite critically low blood-oxygen saturation. Elevated hemoglobin levels in certain patients' blood may play a key role in enabling the respiratory system to sustain low oxygen levels w...
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Researchers have found that cognitive maps stored in the hippocampus and entorhinal cortex are activated when navigating through space physically or mentally. The study used animal models to demonstrate that these mental maps can be created and used during purely mental run-throughs, even without physical movement.
Dr. Jeetain Mittal's NIH grant will support multiscale computational models investigating phase separation in biology, particularly heterochromatin formation and its role in neurodegenerative diseases. The research aims to elucidate the molecular origins of phase separation using innovative models and methods.
Researchers created a virtual rodent with an artificial brain that can move like a real rodent, simulating complex behaviors using biomechanical data from real rats. The model uses deep reinforcement learning and AI to predict neural activity across behaviors.
Researchers discovered that brain's structural features are consistent with a phase transition in humans, mice and fruit flies, suggesting a universal governing principle. The findings could enable new designs for computational models of the brain's complexity.
Researchers discovered that command-like DNs in fruit flies recruit additional networks of neurons to orchestrate complex behaviors. The study shows that these networks work together to produce coordinated actions, transforming the way we understand brain signals and behavior.
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Researchers found that chronic immune suppression after mating makes female fruit flies susceptible to delayed brain deterioration following early-life head injuries. The study establishes a causal relationship between early head trauma and late-life neurodegeneration, emphasizing sex differences in injury response.
A team of neuroscientists developed a new AI algorithm that replicates the brain's visual processing, forming spatial maps and predicting sensory responses. The topographic deep artificial neural network (TDANN) could lead to more efficient artificial systems inspired by the brain's elegance.
A new deep learning AI model, Dev-ResNet, identifies embryonic developmental events in pond snails using video analysis. This breakthrough enables the detection of key features, such as heart function and hatching, with unprecedented sensitivity.
A new study uses computational modeling to understand how ketamine affects individual neurons, leading to changes in brain network function. The model predicts that ketamine can disinhibit network activity by shutting down certain inhibitory interneurons.
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A study published in PLOS Biology found that stressed participants were more likely to help the victim than punish the perpetrator in a simulated third-party intervention task. The researchers observed higher brain activation in regions linked to decision-making and mentalizing when stressed participants chose to help.
A new Bayesian inference framework reduces data size by over 80% while achieving accurate modeling and control of optical power evolution. The approach enables simultaneous exploitation and exploration of a data space to identify suitable candidates for autonomous driving optical networks.
The study suggests that memory plays a pivotal role in shaping consciousness, contrasting the idea that computer-based Information Theory provides a sufficient framework for understanding neural memory. The researchers propose a novel perspective that memory underpins consciousness, introducing the concept of a "brain cloud" to illustr...
Researchers at UCLA Health discovered a novel, energy-efficient mechanism of working memory that reduces metabolic cost even during sleep. The discovery is published in Nature Communications and may provide an early diagnostic for Alzheimer's disease and related dementia.
Researchers from NIMS and Tokyo University of Science developed a compact AI device that utilizes molecular vibrations to predict blood glucose levels in patients with diabetes. The device outperformed existing AI devices with a 50% error reduction, paving the way for low-power AI terminal devices with various sensors.
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Researchers have developed a network model that replicates the experimental findings of how short-term history effects lead to central tendency bias in working memory. The model shows that neural circuits can give rise to both recency and central tendency biases at the same time through a single mechanism.
Researchers developed a new method to accelerate high-resolution ultrasound localization microscopy using deep learning, enabling faster and more accurate imaging of microvascular structures. The technique, called LOCA-ULM, improves spatial resolution and processing speed while maintaining sensitivity for functional imaging.
Researchers discovered that rats without prior knowledge of numbers can develop a sense of numbers when trained with sounds representing two or three numbers. The study found that the brain has a specific area for dealing with numbers, which is separate from the processing of magnitude.
A novel machine learning model has been developed to characterize material surfaces, accurately predicting key electronic properties. The model, which employs artificial neural networks and transfer learning, shows great promise for exploring new materials with superior properties.
Researchers used fMRI and predictive modeling to decode emotional dimensions of spontaneous thoughts, revealing the involvement of default mode, ventral attention, and frontoparietal networks. The study's findings hold promise for daydream decoding and potential applications in mental health.
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A team of researchers from the University of Buenos Aires has developed a method to translate the vocal muscle activity of birds during sleep into synthetic songs. This breakthrough uses electromyography data and dynamical systems models to recreate the sounds of dreaming birds, providing a new window into the subconscious mind of avians.
Researchers found that geraniol reduces oxidative stress and neuroinflammation-mediated cognitive impairment in a mouse aging model. Geraniol treatment improved spatial learning and memory by enhancing anti-oxidant and anti-inflammatory effects.
Researchers at University of Cologne's CECAD Cluster of Excellence discovered that mitochondrial fusion boosts new neuron plasticity. The study found that as new neurons mature, their mitochondria fuse to acquire elongated shapes, sustaining synaptic plasticity and refining brain circuits.
MD Anderson researchers presented studies on combination therapies for AML and lung cancer, tumor microbiomes in immunity, and improved HPV screening. Genetic markers predict extended survival with KRAS inhibitors and may identify patients who benefit from novel combinations.
Weill Cornell Medicine scientists developed a human neuron model that simulates tau protein aggregate spread, a process driving cognitive decline in Alzheimer's disease. The model identified novel therapeutic targets, including the UFMylation cascade, which can potentially block tau spread.
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Researchers at UMass Amherst have identified the most effective AI method for monitoring insect populations using bioacoustics, with deep learning models achieving high accuracy. The study found that machine and deep learning are becoming the gold standards for automated bioacoustics modeling.
A study published in Brain, Behavior, and Immunity found that normal levels of interferon-β are required for normal memory function, and its absence changes nerve cell components in a sex-dependent fashion. The research also showed that higher or lower than normal levels of interferon-β affect the brain in a sex-dependent manner.
A new Deep Learning model based on the Transformer architecture has been developed to predict water and energy demands in agriculture. The model forecasts daily demand for irrigation water seven days in advance with an error margin of less than 2%, enabling effective resource management without autonomy loss.
The latest issues of APA journals focus on treatment options for youth with irritability, exploring collaborative psychopharmacology approaches. Additionally, the studies examine disparities in the use of restraint among psychiatric patients.
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Researchers discovered that mature oligodendrocytes, critical for brain function, can survive for up to 45 days after a fatal trauma, defying the classical programmed cell-death pathway. This finding opens new avenues for understanding and potentially preventing damage caused by aging and neurodegenerative diseases.
Researchers at Hebrew University of Jerusalem introduced a non-invasive technique for evaluating chickpea water status, offering farmers a powerful tool to fine-tune irrigation schedules. The method amplifies both crop yields and water efficiency, resonating with global food security efforts.
A recent study investigated ChatGPT-3.5's ability to produce high-quality summaries of medical research abstracts, finding that it was accurate but not always fact-based and prone to minor inaccuracies. The model showed promise as a screening tool to help clinicians quickly evaluate article relevance but should not be relied upon for c...
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Researchers developed a new model that highlights the crucial role of interactions among neighboring contact sites of nerve cells for brain plasticity. Synaptic plasticity, the brain's method for learning, is shaped by the strength and stability of neuronal connections, which are influenced by both excitatory and inhibitory synapses.
Researchers discovered that brains prioritize integrating muscle spindle input to understand body movement and position. Task-driven neural network models were found to be most effective in predicting limb position and velocity.
A team of researchers has developed the world's first 3D-printed brain phantom, which can be imaged using dMRI. The brain model is made up of microchannels that mimic nerve cells in the brain, allowing for more accurate analysis and research into neurodegenerative diseases.
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Researchers developed machine learning models that can recognize emotions in voice recordings as short as 1.5 seconds with high accuracy comparable to humans. The study used three ML models and achieved an accuracy of over 90%, with potential applications in therapy, interpersonal communication technology and more.
Researchers developed a new open-source system to interface with living neurons, offering enhanced control and precision in measuring neural processes. The system boasts over 500 electrodes, allowing for more data collection and customization, while being 10 times cheaper than commercial systems.
Researchers from UNIGE have developed an AI that can learn a task solely based on verbal instructions, then describe it to another AI, which reproduces the task. This breakthrough is promising for robotics and understanding human language.
Researchers developed chronological age prediction models by analyzing gene expression changes in the prefrontal cortex, identifying genes associated with aging and potential mechanisms. The models showed high correlation with age and demonstrated female and male-specific differences.
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Researchers developed a machine learning system to improve sewer-river model accuracy and efficiency. The innovative approach reduces parameter calibration time and enhances predictions of urban water pollution.
Researchers used a Convolutional Long Short-Term Memory (ConvLSTM) neural network to predict Antarctic sea ice conditions. The prediction results showed a remarkably close alignment with recent satellite observations, confirming the reliability of the forecasting system and its potential for reliable Antarctic sea ice forecasting.
Researchers developed a custom-built, low-cost mesoscope that can adapt to different neuroimaging experiments in live mice and rats. The system offers excellent spatial and temporal resolutions, achieved through its reversible tandem lens configuration, which enables flexible experimentation.
Politecnico researchers developed a new type of neural network called Latent Dynamics Network (LDNet) that can accurately predict the evolution of complex systems in low-dimensional spaces. This approach offers significant innovations over traditional methods, enabling up to 5 times more accurate results with a reduction of over 90% in...
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Researchers at Tohoku University have developed a high-performance spin wave reservoir computing model that utilizes spintronics technology. The breakthrough could lead to energy-efficient, nanoscale computing with unparalleled computational power.
A new computational model uses neural network architecture to generate accurate predictions of airflow while reducing computational cost. It can capture most of the original physics in a flow prediction with relatively little processing complexity.
A study using machine learning classifies galaxy mergers and finds that mergers are not strongly associated with black-hole growth. Cold gas at the center of the host galaxy is necessary for rapid growth, suggesting a more complex relationship between galaxy evolution and supermassive black holes.
The new AI model uses a visual map to explain each diagnosis, helping doctors follow its line of reasoning and check for accuracy. The tool aims to catch diseases in their earliest stages, making it easier on doctors and patients alike.
Researchers used machine learning to identify key predictors of mortality in dementia patients across various types. The study found neuropsychological test results were a better predictor of mortality risk than age-related factors, highlighting the potential for personalized care and more effective interventions.
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Researchers at Salk Institute have created a novel organoid model of the human brain that includes mature, functional astrocytes. This allows for the study of inflammation and stress in aging and diseases like Alzheimer's with greater clarity, revealing a relationship between astrocyte dysfunction and inflammation.
PandaOmics uses advanced AI algorithms to process vast quantities of diverse data, performing gene and pathway analysis and target predictions. The platform has been extensively validated in multiple therapeutic areas, including oncology, inflammation, and immunology.
Researchers have developed a method to decode mouse neural activity, enabling accurate determination of location and direction within an open environment. This breakthrough could inform the design of intelligent machines that navigate autonomously without GPS or satellite guidance.
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Scientists developed an innovative neural cell culture model that replicates the aberrant behavior of TDP-43 in neurons. The model identified NPTX2 as a toxic protein that accumulates in cells containing abnormal TDP-43, leading to neurodegeneration in ALS and FTD.
Scientists at Tokyo University of Science used deep learning to predict single-molecule magnets from a pool of 20,000 metal complexes, identifying 70% accuracy in distinguishing between SMMs and non-SMMs.
A recent study published in PLOS Biology found that the human brain can segregate direct speech from its echo, allowing for reliable recognition of echoic speech. This neural separation is essential for understanding conversations in noisy environments and is supported by magnetoencephalography recordings.
A new AI tool, DeepGO-SE, successfully predicts the molecular functions of unknown proteins with high accuracy. This breakthrough enables researchers to analyze uncharacterized proteins, facilitating tasks such as drug discovery, metabolic pathway analysis, and disease associations.
Researchers have identified a network of neurons controlling right-left movements in the brain, which may help treat Parkinson's disease. The discovery provides insight into how essential movements are produced by the brain.
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