Research on how genomes change over time. Covers hidden DNA structure, chromosome bursts in cancer, plant pangenomes, and microbial adaptation.
Plant scientists combined second- and third-generation genomic technologies to create a more accurate and efficient method for resolving plant pathogen genomes. This breakthrough reduces the time required to sequence genome data from one-and-a-half years to just nine days, while lowering costs from $2 million to $1,000.
Researchers found that jumping genes, also known as transposable elements, play a crucial role in stabilizing the 3D folding patterns of DNA molecules. This discovery contradicts the long-held assumption that the precise order of letters in the DNA sequence dictates the broader structure of the DNA molecule.
A large-scale comparative analysis across 76 diverse species reveals dynamic genomic changes that have allowed arthropods to thrive in various ecosystems. These changes include adaptations in digestion, chemical defense, and exoskeleton structure.
An international team sequenced the genomes of 78 individuals from five indigenous groups in Mexico to understand the demographic history and genetic variation of pre-Hispanic populations. They identified 120,735 single nucleotide variants and found that certain genes were associated with adaptation to physical endurance and other traits.
Scientists discovered two bursts of new genes that drove the evolution of land plants, contradicting previous gradualistic views. These genetic innovations enabled plant multicellularity and adaptation to terrestrial environments.
Researchers successfully sequenced and annotated the giant squid's genome, providing a unique opportunity to explore its evolutionary history. The genomic draft reveals insights into the giant squid's size, growth rate, and age.
A UC San Francisco-led research team has discovered the first conclusive evidence that natural selection may also occur at the level of the epigenome for tens of millions of years. The study found a particular epigenetic mark on the DNA sequence of Cryptococcus neoformans, which should have disappeared during the age of the dinosaurs.
The giant squid's full genome sequence has been published, providing insight into its anatomy and evolution. The genome, similar to other animals, suggests that the squid did not get its massive size through whole-genome duplication.
Scientists discovered more evidence of archaic introgression in immunity-related genes and found a possible resistance to malaria among Papua New Guineans. They also identified genes related to porphyrins, energy metabolism, and olfactory receptors showing signals of Neandertal introgression.
A new study has confirmed the history of tomatoes from South America, from blueberry-sized wild tomatoes to large-fruited common tomatoes. Scientists have reconstructed a putative domestication history of tomato groups, focusing on the intermediate stage represented by SLC, which originated in Ecuador around 78 KYA.
The water lily genome expands the picture of the early evolution of flowering plants, shedding light on key traits like flower development and attractive floral scent. Researchers used high-throughput sequencing technology to analyze the genome and transcriptome of Nymphaea colorata, identifying over 31 thousand protein-coding genes.
A new analytical method has been developed to address the limitations of estimating evolutionary history of various sex-determination systems. The method, based on male mutation bias, reveals that some species share an XY system for several million years before it is lost, as recently as 20-60 million years ago in some lineages.
A study by Tohoku University researchers reveals that ancestral VMAT1 proteins exhibited increased neurotransmitter uptake, potentially linked to higher levels of anxiety or depression. The findings suggest that our ancestors may have been able to withstand higher levels of anxiety.
A team of scientists discovered evolutionarily novel genes expressed in all tumors, which could serve as excellent tumor markers. The new research confirms a theory that the number of oncogenes should correspond to the number of differential cell types, providing a new perspective on cancer prevention and therapy strategies.
The study reveals the Carolina parakeet's rapid extinction was mainly a human-mediated process, with no signs of inbreeding or population decline found on its genome. The genomic analysis suggests that the bird's unique diet may have contributed to its demise, and experts wonder if de-extinguishing the species could be possible.
Researchers have developed a new tool that can analyze 1.4 million genetic sequences simultaneously, allowing them to study species relationships on a larger scale than before. This technology has the potential to reconstruct how life has evolved over hundreds of millions of years and unlock secrets about the code of life.
The Devil Worm's genome reveals an unusually large number of heat-shock proteins and extra copies of cellular survival genes, suggesting its evolutionary adaptation to lethal environmental conditions. The discovery may provide lessons for humans on how to adapt to a warming climate, with potential applications in understanding life bey...
A study published in Nucleic Acids Research reveals that transposable elements have been co-opted by hosts to provide useful functions, such as encoding part of a host protein. The research found tens of thousands of potentially co-opted TE sequences, which are more conserved across species and suggest a key role in mammalian evolution.
Researchers reconstructed the beetle family tree, estimating timing and rates of diversification. Beetle genes facilitating herbivory were acquired through horizontal transfer from fungi and bacteria, enabling adaptability to flowering plants.
A new study reveals that genes from soil bacteria were transferred to algae through horizontal gene transfer, allowing early life to move from water to land. This process, known as terrestrialization, marked a crucial event in the evolution of life on Earth.
Researchers found that Kentish plover (Charadrius alexandrinus) and white-faced plover (Charadrius dealbatus) diverged around half a million years ago due to sea level changes. The study revealed high genetic divergence on sex chromosomes, suggesting sexual selection played a role in species evolution.
Researchers identified genomic elements regulating optix gene expression in Heliconius butterflies, found to be necessary for normal pattern development. These elements evolved in parallel in distantly related species with similar patterns, highlighting the complexity of butterfly wing patterning.
Researchers analyzed genome assemblies of 20 butterfly species and found a high amount of gene flow among them, even between distantly related species. This challenges the idea that species are fixed entities and suggests hybridization as a key process in biological diversity.
A new study finds that hybridization significantly influences the evolutionary history of Heliconius butterflies, contributing to their unique wing patterns. The research suggests that hybridization can provide genetic material for rapid adaptive divergence and radiation, leading to beneficial consequences in species evolution.
New studies reveal a broader range of genetic code deviations than previously thought, particularly among green algae. The research suggests that these changes may have driven the evolution of unique mitochondrial genome organizations.
The One Thousand Plant Transcriptomes Initiative reveals the complex history of land plants and green algae, including previously unknown duplications and expansions of genes. The data shed light on plant evolution, relationships between lineages, and potential avenues for evolutionary development.
A recent study published in Nature reveals a new framework for understanding the evolution of green plants over 1 billion years. The research, led by an international consortium of scientists, generated gene sequences for over 1100 plant species and provides insight into how plants evolved to produce useful chemicals.
The One Thousand Plant Transcriptomes Initiative reveals the timing of whole genome duplications and the origins of key gene families contributing to fundamental genetic innovations in green plants. The study provides a framework for understanding plant diversity and evolutionary innovations.
By blocking the expression of c-Answer, a newly identified gene, researchers found that tadpoles can no longer regrow lost tails or limbs. The loss of this gene may have led to the evolution of appendage regeneration in cold-blooded animals.
A study published in New Phytologist reveals the evolutionary history of oaks, showing that different lineages are driven by distinct sets of genes. The research highlights the key role oaks play in supporting ecosystems and provides insights into conservation efforts.
Molly Schumer and Bérénice Benayoun are the 2019 recipients of the Rosalind Franklin Young Investigator Award. Schumer investigates hybridization in non-mammalian organisms, while Benayoun explores genomic regulation and aging in humans. The award recognizes outstanding genetics research.
Researchers at UMass Medical School and the University of Queensland identified a novel genetic defense system in koalas that controls retrovirus production through germline cells. This innate genome immune response recognizes viral RNAs via anti-sense piRNAs, suppressing assembly of viral particles.
Researchers discovered a 'senescence' pattern in influenza virus surface protein mutations, making it harder to predict future changes. This understanding can improve vaccine strain selection, ultimately enhancing protection against seasonal flu outbreaks.
Researchers found that genetic diversity makes a striking comeback in the host population after resistance evolution, thanks to an interplay between selection and population growth. The study's findings suggest that eco-evolutionary feedback plays a key role in shaping molecular evolution during species interactions.
A recent study reveals that parasitic flukes have a long evolutionary history, with genome comparisons showing significant adaptations to different hosts. The research team found that fasciolid flukes may have originated in ancient African elephants and later expanded into Eurasian herbivores.
The genome comparison of almond and peach trees sheds light on their evolutionary history and the role of mobile genetic elements in diversification. The study found that transposons may have driven the differences between the two species, including variations in flavor and fruit quality.
Researchers at Karolinska Institutet analyzed the whole genome of 1,000 Swedish individuals and identified 61,000 new DNA sequences, including 80 genes linked to diseases. These new sequences are found in all major human populations, indicating they are ancient and widespread
Researchers identified microRNAs that regulate plant reproduction in ancient liverwort species, also found in modern crops. The discovery may lead to new applications for predicting harvest times and improving crop yields.
The Penguin Genome Consortium has sequenced high-coverage penguin genome sequences, providing an unparalleled amount of information on the genomic landscape of all living penguin species. This study reveals key insights into the evolution of life on the ice and will help predict population trends under future climate change scenarios.
Scientists identified over 11,000 families of grouped genes in genomes of different species, with a third being part of conserved clusters. The study found that natural selection favors gene organization, making it easier to regulate genes, and that horizontal transfer may be less common than previously thought.
A team of scientists has solved the mystery of 'Fraser's Clawed Frog', an unusual species found in West Africa. The study, published in PLOS ONE, reveals that the frog inhabits hot and arid regions of northern Cameroon and Ghana, contradicting previous assumptions about its geographic origin.
Scientists at Michigan State University have received a four-year, $2.6 million grant to investigate tuber evolution in plants like potatoes and tomatoes. The researchers aim to uncover the genetic mechanisms behind this adaptation, which allows plants to store energy underground and survive harsh conditions.
A research team has sequenced the genome of Dysdera silvatica, an endemic species in the Canary Islands, providing valuable information on its genetic basis and trophic specialization. The study reveals a high complexity genome with repetitive elements and identifies 36,000 protein-coding genes.
Researchers discovered a gene variant, UPA2, in wild teosinte that can be used to increase maize yields under high-density planting. The introduction of this allele into modern maize resulted in significantly increased yield and upright plant growth.
Researchers at the University of California San Diego have developed a groundbreaking system for determining gene expression based on machine learning. The new method leverages chromatin biology and molecular features to identify expressible genes with high accuracy, providing a genetic 'Rosetta Stone' for biologists.
A recent study in Nature Ecology and Evolution found that gene arrangements in the genome have played a key role in animal evolution. The researchers discovered that genes present together in several species are also active in the same cells, highlighting a new perspective on investigating cell type identities.
A recent study has found that intense fish harvesting can cause rapid evolutionary changes, including changes in growth rates and maturity. The research, published in Science, used genomic data to analyze the effects of fishing on Atlantic silverside populations.
Decades-old frozen fish reveal roots of rapid evolutionary adaptation to human-induced environmental change. Genomic analysis shows that multiple genetic pathways can lead to similar traits, supporting the idea of diverse evolutionary paths.
The study provides insight into how the Komodo dragon's DNA encodes its astounding characteristics, including its ability to detect prey from far away. The team discovered changes in genes that increase the lizard's aerobic capacity, allowing it to achieve near-mammalian metabolism.
Researchers have identified the genetic basis of pufferfish spines, which share developmental pathways with other vertebrates. The study reveals that the spines evolved as a unique adaptation for protection during inflation.
Researchers discovered genome-wide variations in gene expression between females and males in mammalian species. The study revealed hundreds of conserved sex-biased gene expressions contributing to differences in traits.
The study presents the draft genomes of three jellyfish species, revealing venom-related genes and evolutionary mechanisms. The research identified 117 putative venom proteins, including a toxin gene found only in cnidarians, providing insight into the evolution of cnidarian venom.
Researchers have unraveled key enigmas in evolutionary biology, revealing how ruminants obtained a more efficient use of plant food and developed specialized teeth to exploit bacteria's digestive capabilities. The study also provides insights into the explosive growth of deer antlers and potential cancer-like cell growth mechanisms.
A genome study has revealed the evolution of ruminants, including deer, antelope, and giraffes. The research provides a foundational genomic roadmap for understanding how evolution has shaped these animals, as well as their unique digestive system and adaptations to environmental changes.
The Ruminant Genome Project has provided unprecedented insights into the genomics, evolution and adaptation of ruminants, a group with significant importance in agriculture, conservation and biomedical fields. The study revealed large declines in ruminant populations nearly 100,000 years ago, coinciding with human migration out of Africa.
A team of life scientists at UCLA discovered that sea otters have low genetic diversity, which could endanger their health. The researchers found evidence of potentially harmful genetic variation and mating between closely related ancestors in the sea otter genome, similar to other endangered species with small population sizes.
A recent study by UMass Amherst researchers found that polar bears possess fewer copies of genes related to olfactory receptors and salivary amylase, adaptations that enable them to thrive on a fully carnivorous diet. This discovery sheds light on the genomic foundation of ecological adaptation in polar bear evolution.
A study analyzing gene copy numbers in polar bears and brown bears reveals nearly 200 genes with significant variations, including those involved in olfactory receptors, salivary amylase, and fatty acid metabolism. These differences reflect dietary adaptations between the two species.
A team of researchers, led by Jennifer Brisson and Benjamin Parker, discovered genes from a densovirus that determine whether pea aphids produce winged or wingless offspring. The study sheds light on the genetic mechanisms underlying phenotypic plasticity in insects.
Researchers analyzed human remains from 21 archaeological sites to study the impact and evolution of Yersinia pestis during the first plague pandemic. They reconstructed 8 new genomes from Britain, Germany, France, and Spain, revealing a previously unknown level of diversity in Y. pestis strains.