Articles tagged with Phosphatidic Acids
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers from the Polish Academy of Sciences propose nitrogen-doped polycyclic aromatic hydrocarbons as potential OLED emitters, offering improved energy efficiency and color purity. The new compounds achieve high external quantum efficiencies, outperforming existing donor-acceptor emitters.
A collaborative initiative aims to establish common protocols for assessing and comparing diffuse optics systems used in medical diagnosis. The study presents the results of a multi-laboratory comparison of 12 institutions and 28 systems, proposing simple numeric values for easy comparison across instruments.
Researchers investigated the use of intranasal human milk as a stem cell therapy for preterm infants with intraventricular hemorrhage. The study found that preterm infants could tolerate nasal milk therapy without major safety events, paving the way for further research on long-term outcomes.
The study compares current recommendations for ventilation and chest compression versus ventilation during neonatal resuscitation using an ovine model. The findings suggest that optimizing ventilation could reduce the need for chest compressions and improve gas exchange in neonates, potentially improving overall outcomes.
A randomized clinical trial found that outreach messages were minimally effective at promoting scheduling of adolescent well care visits, but had limited impact on completing visits. Efforts to address widening disparities are needed.
A study found that fetuses with single-ventricle congenital heart disease are more susceptible to social-emotional problems compared to those with two-ventricle congenital heart disease. Infants with impaired prenatal brain growth also experience worsened language, cognitive, and motor outcomes by 18 months.
A randomized controlled trial found that furosemide increases the risk of electrolyte adverse events but no difference in hearing loss or nephrocalcinosis was observed. The study suggests caution when using furosemide in preterm infants at high risk for bronchopulmonary dysplasia.
A new study examines the effect of rapid infusion of sodium bicarbonate on gas exchange and coronary and cerebral perfusion in the immediate post-resuscitation phase. The study found that rapid administration led to a significant rise in myocardial and cerebral perfusion, as well as higher levels of exhaled carbon dioxide.
Placental bulge sign on prenatal ultrasound or MRI significantly aids diagnosis of severe placenta accreta spectrum disorder, warranting hysterectomy over conservative management. The sign's accuracy and sensitivity are notable, making it a valuable tool for maternal counseling.
A hot topic symposium session will discuss a multipronged approach to addressing childhood adversity and promoting resilience. The effect of adverse childhood experiences on health outcomes is well recognized among pediatric practitioners.
The Pediatric Academic Societies Meeting predicts major child health legislative and policy changes over the next four years. The session will focus on five key areas, including health insurance coverage, pediatric drug development, and healthcare disparities/poverty, with experts estimating their impact on vulnerable populations.
The Pediatric Academic Societies 2021 Virtual Meeting will showcase the latest clinical and scientific advances in pediatrics. The conference features a full scientific program with over 60 specialties presenting, as well as opportunities for networking and collaboration.
Scientists from IPC PAS develop holographic OCT tomography, capturing cornea in a fraction of a second with high resolution, without contact or anesthesia. This breakthrough technology enables sharper images even with micro-movement of the eye, revolutionizing diagnosis of eye diseases.
Researchers found that less than 10% of protected areas are home to invasive species, but almost all are at risk due to nearby human activity and lack of monitoring. The study highlights the need for increased efforts to monitor and record invasive alien species in protected areas.
The new device developed by the Institute of Physical Chemistry uses non-contact printing to test antibiotic combinations and concentrations. It offers flexibility and precision, allowing users to produce sterile plates on demand with different antibiotics in various combinations.
Scientists have discovered that more energy can be stored by charging less frequently, but right up to 100%. The study found that dividing the storage system into compartments increases energy storage. This discovery may revolutionize electric car battery technology and lead to significant increases in capacity.
Researchers at the IPC PAS and WUT have developed a new, solvent-free drug encapsulation method that uses a pre-assembled metal complex incorporating the drug molecule. This approach could dramatically improve the efficiency of drug encapsulation in MOF materials and open the way to formulating vast arrays of 'drug@MOF' composites.
The American College of Cardiology has released the first competency statement for nurse practitioners and physician assistants in adult cardiovascular medicine. The document outlines core competencies for systems-based practice, medical knowledge, and procedural skills to improve access to care and enhance patient satisfaction.
Scientists have elucidated the mechanism of controlling autophagy through liquid-liquid phase separation, revealing a novel structure responsible for progression. The discovery has significant implications for understanding various intracellular phenomena and developing autophagy-specific control agents.
A new study suggests that dofetilide, an FDA-approved antiarrhythmic drug, may counteract pathological changes in potassium channels associated with pulmonary arterial hypertension. In experimental models, dofetilide inhibited PAH-related vascular remodeling and improved lung function.
Researchers analyzed 12,315 protected areas across 152 countries to assess their impact on reducing anthropogenic pressures. Protected areas in temperate and forested regions have slowed human pressure, with countries with higher socioeconomic development experiencing lower rate increases.
A recent study found that while protected areas are reducing deforestation, their effectiveness varies, and conventional management indicators do not show the whole picture. Approximately half of the studied areas showed no deforestation, and 29 out of 36 had a positive impact in mitigating deforestation.
Researchers developed a method to track the activity of phosphatidic acid spatially and temporally using a fluorescence resonance energy transfer-based biosensor. The study found that phosphatidic acid plays a key role in plant stress tolerance, particularly under salt stress conditions.
A study by Herrera et al. reveals that federal protections in Brazil's Amazon reduce deforestation more effectively than state-level measures. The results suggest that the effectiveness of protected areas depends on the level of government involvement.
A VA study examined over 600,000 veterans with diabetes and found that health outcomes were similar regardless of whether primary providers were physicians, nurse practitioners, or physician assistants. The results suggest using these providers in primary care may improve healthcare efficiency.
The world's protected areas are failing to conserve biodiversity due to inadequate resources, with only 4-9% of species represented within adequately resourced PAs. The study recommends using simple indicators to measure PA effectiveness and prioritizing conservation actions to address the growing biodiversity crisis.
A new study reveals nearly 2 million square kilometers of global protected areas have been downgraded since 1892, with 90% of recent US events linked to industrial-scale development. The report warns that these changes could embolden other countries and threaten conservation efforts worldwide.
Researchers found that certain surgeries, such as colorectal and cardiovascular surgeries, increase the likelihood of patients continuing to refill opioid prescriptions. Generalist nurse practitioners and physician assistants may also be overprescribing opioids, suggesting a need for education and better oversight.
The 2020 US Census resulted in a significant undercount of young children, impacting healthcare resources and funding. Pediatricians urge communities to take action to ensure all children are counted, as the Census has far-reaching implications for education, nutrition, and special education.
A new study in Massachusetts aims to improve health and social outcomes for maternal-infant dyads impacted by Opioid Use Disorder (OUD) through sharing best practices, educational materials, and data collection. The initiative resulted in significant increases in skin-to-skin contact and decreases in pharmacologic therapy.
A new study examining opioid fill patterns among Medicaid-enrolled children in the US revealed that prescriptions for these age groups were relatively rare, with an adjusted rate of 0.8% by 2016. The study also found that opioids were most frequently prescribed in combination with other pain relievers.
A new study found that text message reminders significantly improved timely HPV vaccine series completion among eligible adolescents. The study showed that even when compared to historical controls, those receiving text message reminders had higher rates of completing the full vaccine series.
A new study reveals that HPV vaccine coverage is far behind other infant vaccines, with only 13 and three US states reaching above 60% coverage by 2016. The study tracked over 7.5 million children from 2003 to 2016 and found increased uptake among girls and boys, but still fell short of the Healthy People 2020 goal of 80%.
Despite available safety and effectiveness, HPV vaccine coverage rates remain suboptimal. Pediatricians and nurse practitioners report using various strategies, including prompts, communication tools, and performance feedback, to improve HPV vaccination rates.
A national survey of pediatricians and family physicians reveals substantial progress in recommending HPV vaccination to adolescents over the past five years. However, significant areas for improvement exist, including physician communication style and practice-based delivery methods.
A study found that individuals residing near protected areas in France exhibit higher levels of pro-environmental behavior, including increased support for environmental associations and participation in citizen science programs. The research attributes this trend to the inspirational impact of wilder landscapes on nature awareness.
A study found that at least six states with high opioid abuse rates have restrictive scopes of practice for nurse practitioners, limiting their ability to prescribe medications like buprenorphine. In less restrictive states, NPs were more likely to receive waivers and access these life-saving medications.
A new study in the Serengeti-Mara ecosystem highlights how human activity near protected areas affects wildlife and ecosystem function. The results show that human pressure has caused wildlife to migrate to the core of the park, resulting in changes to fire regimes, grazing patterns, and increased vulnerability to droughts.
African protected areas with lions require approximately $1,000-$2,000/km2 in funding for effective conservation. The total annual funding deficit is estimated to be $0.9-2.1 billion, with 88-94% of individual PAs being underfunded.
Researchers find that a previously unreported intermediate radical zinc oxo-alkoxide cluster with gapless electronic states is formed before the growth of semiconducting ZnO phase. The transformation from insulator to conductor-like material occurs rapidly, and further heating leads to semiconductor properties.
Researchers from the Institute of Physical Chemistry of Poland have developed new substrates for Surface Enhanced Raman Spectroscopy (SERS) that guarantee signal enhancement and repeatability. These substrates enable the routine detection of small amounts of chemical compounds, including organic molecules and specific bacteria.
Scientists create nanoparticles that can change their surface topography under light control, enabling precise control over chemical reactions. This breakthrough allows for more efficient and selective catalysis, with potential applications in multistage reactions and simplified post-reaction processing.
Researchers analyzed over 40,000 protected areas worldwide to determine areas needing further protection. The analysis found that nearly half of mountain ranges lacked stringent PAs and failed to meet biodiversity conservation goals.
A new study examining factors associated with sexual coercion among 10th graders in a rural high school found that sexual coercion was reported by 18 percent of students. The research identified predictors including age, race, ethnicity, prior substance use, and controlling relationship behaviors.
A new study examines the effectiveness of the ScreenQ tool in measuring screen-based media use in children. The research found that the ScreenQ demonstrated strong internal consistency and good reliability.
A survey of pediatricians found that delays in receiving influenza vaccine from private and VFC stock pose problems, with 56% delaying vaccinations for patients whose vaccines are out of stock. This highlights the need for systematic changes to address these delays and increase uptake of influenza vaccine among children.
Researchers found that children exposed to SSRIs before birth had better executive functions, even after controlling for mother's mood. The study suggests a potential developmental advantage but also raises concerns about increased anxiety.
A new study found that hospitals caring for seriously ill children rely heavily on public payers like Medicaid and CHIP. The research suggests that reducing federal funding for these programs could destabilize specialty care referral networks, particularly affecting privately-insured children with chronic conditions.
A new study found that abused rural children are younger, more likely to have public insurance, and live in zip codes with lower median household incomes. The study used the 2012 Kids' Inpatient Database and U.S. Census data to analyze rates of child physical abuse hospitalizations across urban-rural categories.
A new study found that increased childhood stress negatively impacts school performance, while strong protective factors lead to better outcomes. The research analyzed over 65,000 children aged six to 17 and discovered a significant correlation between adverse childhood experiences and poor academic performance.
A new study published in JAMA Dermatology reveals that dermatologists are more accurate than Physician Assistants (PAs) in diagnosing early stage skin cancers. For every suspected case of melanoma, PAs needed to biopsy over 39 pigmented lesions compared to just 25 for dermatologists.
Using a super resolution microscopic technique, researchers have developed a method to follow chemical reactions in very small volumes, including inside living cells and individual organelles. This breakthrough enables the study of the chemistry of life with unprecedented precision.
Only one-third of countries meet global targets for protected area connectivity, with EU Member States averaging 18.9% connected land coverage. The study recommends designating new PAs in strategic locations to enhance connectivity and support biodiversity conservation.
Researchers have developed a method to produce high-quality perovskite photovoltaics using mechanochemistry, resulting in improved efficiency and reduced structural defects. The production process involves grinding powders to create homogeneous perovskites with fewer defects, which improves the cell's performance.
Researchers discovered that small droplets evaporate more slowly than predicted by current models, affecting climate modeling and internal combustion engine design. The equation developed can be used to create more accurate climate models and design more efficient cooling units.
Rutgers scientists found that eliminating an enzyme can increase risk of cancer and inflammation, while fine-tuning its activity could prevent obesity and related diseases. A balanced diet is crucial for maintaining the enzyme's balance.
A German Federal Institute for Risk Assessment study found that people perceive synthetic substances and heavy metals as greater health risks than natural contaminants like mercury and dioxin. Awareness about lesser-known contaminants like pyrrolizidine alkaloids and arsenic is low, particularly among younger populations.
The European Society of Anaesthesiology and Intensive Care debates physician-assisted suicide, with advocates arguing for respect for autonomy and compassion. The opposition emphasizes the importance of preserving dignity and the value of human life, regardless of suffering or burden to others.
Researchers from Poland's Institute of Physical Chemistry found that quantum rotations can follow classical rules under specific conditions. The discovery confirms a new model describing jump rotations in molecules.
Researchers at the Institute of Physical Chemistry of Poland have demonstrated that increasing light intensity can accelerate chemical reactions by several dozen percent. This discovery has implications for various applications, including microscopic imaging techniques and ultra-fast spectroscopy.