Articles tagged with Science Administration
A study by the Alliance Foundation Trials shows that combining immunotherapy and chemotherapy before surgery can help more patients with locally advanced non-small cell lung cancer undergo complete cancer resection, improving their long-term health. The treatment also led to high rates of lymph node clearance and successful surgical re...
A new blueprint for creating research agreements enables respectful research with Tribes and on Tribal lands. The guidance defines rights of Tribes and researchers, aiming to avoid extractive practices and protect data sovereignty.
The US administration's attacks on biomedical research and vaccination policies have severe consequences for healthcare protection and global public health. Certain scientific topics in infectious diseases and immunology have been deprioritized, and the US has withdrawn from major global public health programs.
Dr. Noritaka Ichinohe challenges the long-held assumption that averaging away individual differences is necessary in psychiatric research. Instead, biological heterogeneity is seen as a phenomenon demanding explanation. The author's work on primate brain mapping and molecular subtyping has identified convergence points between species ...
Groundbreaking research by Dr. Bruce M. Cohen has uncovered critical abnormalities in energy metabolism and cellular connectivity that contribute to psychiatric disorders. The study's findings suggest therapeutic avenues that may be better targeted and more effective than current treatments.
A report by Digital Science assesses Australia's National Persistent Identifier (PID) Strategy, highlighting strengths and weaknesses. The study recommends improving data citation and ORCID adoption for non-traditional research outputs.
A renowned geneticist, Dr. Martin Alda, has made a groundbreaking discovery that bipolar disorder is composed of multiple genetically distinct disorders, transforming treatment approaches worldwide. His research also highlights the importance of combining basic research with clinical observations to advance psychiatric care.
Professor Siegfried Kasper reveals biological bases of psychiatric disorders alongside psychosocial determinants, influencing treatment protocols globally. His pioneering research transformed approaches to treatment-resistant depression, improving millions of lives.
Dr. David Rubinsztein shares his personal journey from childhood curiosity to discovering autophagy, a natural process that clears toxic proteins causing devastating neurodegenerative diseases. His research has established autophagy upregulation as a viable therapeutic strategy for conditions affecting millions worldwide.
Leading trauma researcher Professor Philip Hyland's work on Complex PTSD fundamentally changed World Health Organization diagnostic criteria, impacting how clinicians worldwide assess and treat trauma survivors. His innovative measurement tools, such as the International Trauma Questionnaire, challenge decades of clinical tradition and...
Dr. Yehezkel Ben-Ari's Neuroarcheology framework links developmental mechanisms to disorders, offering new hope for previously untreatable conditions. His groundbreaking work has transformed our understanding of brain development and malfunctions.
Researchers have found that psychedelic compounds can reverse a cascade involving brain-resident cells and immune cells, increasing fear behavior when chronic stress disrupts signaling. This finding represents a paradigm shift in understanding psychedelics' therapeutic potential.
Researchers using multi-omics tools analyze blood-derived immune cells to chart disease heterogeneity in unprecedented detail. This approach enables exploration of pre-existing immune states shaped by past infections, environmental exposures, and genetic predisposition.
Three NSF-funded investigations are launching on NASA's SpaceX CRS-32 mission to ISS National Laboratory. Investigations aim to advance pharmaceutical manufacturing, develop new materials, and study active matter in microgravity environment.
The USA Center for Rural Public Health Preparedness is leading a four-year project to identify and overcome obstacles in adopting the latest trauma triage guidelines. The goal is to produce guidelines that are equally useful and relevant for anyone, whether they are in urban or rural areas.
Ryan Amberger, a Ph.D. candidate in physics at Texas A&M University, has been selected for a 2025 Los Alamos-Texas A&M Fellowship to conduct dissertation research on nuclear astrophysics. He aims to improve understanding of the s-process by studying neutron cross sections.
Four UTA faculty members - Cameron, Dias, Shiakolas, and Yuan - recognized by the National Academy of Inventors for their outstanding research discoveries. Their innovations have made a tangible impact on society through patents, licensing, and commercialization.
Dr. Catherine Champagne, a renowned nutrition expert, has been selected as an Excellence in Nutrition Fellow by the American Society for Nutrition. She is being recognized for her outstanding contributions to the field of nutrition, including her leadership in dietary assessment and nutrition counseling.
Dr. Romina Mizrahi's PET-based neuroimaging sheds light on brain workings, integrating genetics, environment and imaging to understand psychiatric illness as a complex biological puzzle. She advocates for precision psychiatry paradigm with customized treatments based on molecular profiles, and calls for diversity in academic leadership.
Neuro-immunologist Stephen Hauser has won the 2025 Breakthrough Prize in Life Sciences for his role in identifying the immune system's primary driver of damage to nerve cells in multiple sclerosis. His B-cell theory has led to the development of therapies that have transformed treatment, reducing relapses and improving prognosis.
The NASA Hubble Fellowship Program has selected 24 outstanding astrophysicists for the 2025 class, providing up to three years of support at a U.S. institution. The fellowships aim to foster excellence and leadership in astrophysics by supporting innovative early-career researchers.
The SUMMIT trial shows tirzepatide reduces the risk of cardiovascular death or worsening heart failure in patients with obesity, chronic kidney disease, and heart failure, while improving kidney function. Researchers found significant improvements in both patient groups with and without chronic kidney disease.
Researchers propose GLDH as a more liver-specific biomarker for detecting liver injury, offering greater specificity than current ALT and AST tests. The test performed similarly to ALT for detecting liver injury but was not impacted by associated muscle injury.
The Endocrine Society expresses concern over the administration's plan to reorganize HHS, slashing federal funding and staff, which will hinder medical discoveries and approve new treatments. The society warns that politicization of scientific grants will harm millions of people needing medical care for endocrine conditions.
The Weill Cancer Hub East will unite world-class experts in cancer biology, immunology, nutrition and metabolism to drive pioneering research. The hub aims to improve the effectiveness of immunotherapy, a promising approach for many types of cancers.
Many teenagers enter adulthood with significant risk factors for cardiovascular disease, and emerging adulthood is a key time to address these risks. Interventions such as health practices, lifestyle changes, and improved access to healthcare can help reduce the risk of developing future cardiovascular disease.
Full Waveform Inversion (FWI) technology provides unprecedented precision in seismic imaging, breaking resolution limitations of traditional methods. It characterizes complex structures within the Earth's interior and offers higher-resolution subsurface models.
Researchers have identified a potential new gene target, FLT1, that could be edited to treat sickle cell disease by increasing fetal hemoglobin levels. The study found 14 new genetic markers associated with fetal hemoglobin production, which could help preserve the type of hemoglobin present at birth.
The Crew-10 mission will support cutting-edge biomedical investigations and NSF-funded physical science projects through the ISS National Lab. Astronauts will conduct experiments on the International Space Station, with findings benefiting humanity and driving commerce in low Earth orbit.
A new diagnostic method called flicker optoretinography (f-ORG) analyzes the retina's reaction to light, helping to detect danger before symptoms appear. The technique detects even minor changes in photoreceptors, providing valuable insights into retinal health.
Researchers have developed a new method to deliver antibiotics directly into the bladder tissue, eliminating over 90% of bacteria from the bladder. The nanogel-based drug delivery system shows promise in treating UTIs and could potentially lead to an eventual cure.
The Scientific Advisory Committee (SAC) of Stand Up To Cancer has been strengthened by the addition of three new members: Drs. Armstrong, Dahlberg, and Philipson. The new experts bring critical knowledge in pediatric oncology, biostatistics, and healthcare economics to complement existing expertise.
Dr. Melissa Perreault's research combines cutting-edge science with Indigenous knowledge, pioneering sex-specific biomarkers, neuroethics, and psychedelics research in neuropsychiatry. Her work aims to promote inclusive methodologies that consider diverse worldviews and cultural understandings of health.
Tom Maniatis, a prominent molecular biologist, is warning of the impact of the NIH's planned 15% cap on indirect costs. He believes small independent institutions will be harmed, stifling technological innovation and scientific progress. The scientific community must act swiftly to prevent this from happening.
A recent study from the University of Missouri and Yale University found that restricting flavored e-cigarettes leads to a decrease in vaping among young adults. However, this restriction also increases traditional cigarette smoking among young adults compared to states without such restrictions.
ABT-263 eliminates harmful aging cells in the gut, reducing inflammation and lowering cancer risk in a mouse model of GI cancer. The study suggests that removing senescent cells could help prevent radiation-related GI cancer, highlighting the potential of senolytic drugs as a preventive treatment.
Researchers at Virginia Tech have developed a method to convert gut bacteria into mini protein factories that produce and release sustained flows of targeted proteins within the lower intestine. This approach eliminates a major roadblock in delivering drugs to this part of the body, offering potential treatment for chronic diseases.
Researchers created optimized DNA hydrogels with fewer nucleic acids, achieving efficient and sustained drug release. The new hydrogel units showed prolonged persistence of at least 168 hours post-administration in mice, contributing to anti-tumor effects.
Researchers at Virginia Tech have developed a way to convert gut bacteria into miniature protein factories that produce and release targeted proteins inside the lower intestine. This breakthrough could potentially treat chronic diseases.
A new method allows for accurate measurement of blood-brain barrier permeability, revealing that many CNS drugs penetrate the barrier rapidly. The study found that plasma proteins play a crucial role in maintaining brain delivery of lipophilic agents.
A study found that excessive Tibetan Plateau spring warming was the primary factor driving catastrophic June 2024 heavy rainfall in southern China. The research used the ESM to simulate extreme warm temperatures over the TP and heavy rainfall in S. China, reproducing approximately 55% of the observed anomaly.
A new 3D bioprinted gastric cancer model successfully replicates the unique characteristics of individual patients' tissues, predicting drug responses and prognosis with high accuracy. This innovative platform enables rapid evaluation within two weeks, contributing to personalized cancer treatment development.
Researchers at Tokyo University of Science have found that opioid delta-receptor agonists can alleviate stress-induced IBS symptoms in a validated mouse model by targeting the central nervous system. The study suggests that these drugs could provide a more definitive solution for IBS with minimal adverse effects.
Dr. Kerry Ressler's research bridges the gap between molecular neuroscience and clinical psychiatry to understand PTSD's genetic architecture. Recent breakthroughs have identified over 100 significant genetic loci, representing a major step toward translating scientific discoveries into effective treatments.
Lauren Berger, a Texas A&M University doctoral student, has been awarded a prestigious FINESST grant from NASA to study Martian dunes. She aims to analyze the shapes and patterns of compound dunes on Mars using high-resolution images, comparing them to similar dunes on Earth.
The project creates a comprehensive U.S.-Japan flood risk data inventory and develops a two-way coupled, multi-scale, agent-based model that considers marginalized groups. Researchers will use the developed model to evaluate the impact of insurance policies on these groups.
Researchers developed a novel inhalable therapeutic delivery system for lung cancer using mucoadhesive protein nanoparticles inspired by marine mussels. The approach leverages the adhesive properties of mussel proteins to enable selective payload release and minimize adverse effects.
Leona M. Flores, a renowned researcher with expertise in biomedical sciences, has been appointed as the new vice president of research operations at Sanford Burnham Prebys. She will oversee the successful execution of research projects and provide administrative support to advance scientific discoveries.
Dr. Carrie Bearden's groundbreaking work combines genetic and brain development insights to identify early warning signs of psychosis in adolescents. Her research has exciting implications for personalized medicine and targeted preventive treatments.
The Xinjiang Institute of Ecology and Geography has launched several initiatives to combat desertification, including a Green Technology Park in Mauritania and the African Great Green Wall initiative. These efforts aim to address livelihood crises and improve economic development in Africa.
Robert McKeown, a distinguished service award recipient, has made significant contributions to nuclear physics over the past 50 years. He supervised 14 Ph.D. students and educated thousands of people worldwide through teaching and lecturing at prestigious institutions.
Renowned neuroscientist Dr. Michael Meaney discusses his pioneering work on the intricate relationship between genes and environment in shaping brain health, with implications for public health policy and early intervention programs.
Emory University MD candidate Fayzan Rab's research investigates the economic and public health implications of psychedelic therapy implementation. His work emphasizes making these innovative treatments accessible to traditionally underserved communities.
Neuroscientist Professor Raz Yirmiya reveals a vital link between inflammation and depression through groundbreaking research. His work suggests that both activation and suppression of the immune system can trigger depressive symptoms, highlighting the need for personalized treatment approaches.
Dr. Cathy Barr's groundbreaking research sheds light on the genetic foundations of conditions including depression, ADHD, reading disabilities, and Tourette syndrome. Her work has the potential to lead to more targeted treatments and reduce stigma around psychiatric disorders.
Neuroscientist Inga Neumann discusses groundbreaking research on oxytocin, a neuropeptide that shapes social behavior and emotional responses. Her work has significant implications for treating social anxiety disorders and understanding stress resilience.
The Biden-Harris administration has awarded the Enrico Fermi Presidential Award to three US Department of Energy scientists for their groundbreaking contributions to nanoscience, electroanalytical chemistry, and fusion. Their work is expected to have a lasting impact on energy transformation and creation.
Dr. Munir Gunes Kutlu's groundbreaking research reveals specific neural mechanisms that transform sensory inputs into behavioral outputs. The discovery sheds light on the brain's dopamine system, particularly in processing information about environmental cues and rewards.
Renowned neuroscientist Dr. Peter Kalivas discusses his groundbreaking work on the tetrapartite synapse, a complex cellular structure influencing addictive behaviors. His research has revolutionized addiction treatment by identifying novel therapeutic targets beyond traditional neurotransmitter systems.
Dr. Edo Ronald de Kloet shares insights on cortisol's dual role in protecting and damaging the brain through mineralocorticoid receptors (MR) and glucocorticoid receptors (GR). His discovery has transformed our understanding of stress-related mental disorders and led to novel therapeutic pathways.