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World-first trial offers new hope for type 1 diabetes

A world-first human trial shows that a commonly prescribed rheumatoid arthritis drug can safely and effectively preserve the body's own insulin production and suppress the progression of type 1 diabetes. The drug, baricitinib, was found to be effective in maintaining insulin production in people who initiated treatment within 100 days ...

SourceSt Vincent's Institute of Medical Research·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateDec 6, 2023

More than $13M awarded to study childhood obesity interventions in rural and minority communities in Louisiana and Tennessee

Researchers aim to determine optimal duration and intensity of behavioral interventions for childhood obesity among rural and minority children. The five-year study, funded by the Patient-Centered Outcomes Research Institute, will enroll 900 parent-child pairs and compare different 'dosing' combinations of face-to-face intervention time.

Coronary heart disease before age 45 may increase risk of dementia later in life

Research found a significant linear relationship between age of coronary heart disease onset and dementia, highlighting the detrimental influence of premature cardiovascular events on brain health. Adults diagnosed with coronary heart disease at a young age may be at increased risk of developing dementia, Alzheimer's disease, and vascu...

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateNov 29, 2023

SMART researchers pave the way for faster and safer T-cell therapy through novel contamination-detection method

A novel contamination-detection method enables faster and safer T-cell therapy production, reducing the risk for patients and speeding up treatment. The method uses cutting-edge technology to identify harmful microorganisms within 24 hours.

SourceSingapore-MIT Alliance for Research and Technology (SMART)·JournalMicrobiology Spectrum·TypeRandomized controlled/clinical trial·DateNov 27, 2023

First comprehensive guideline on using biomarkers for monitoring Crohn’s disease

The American Gastroenterological Association released a new guideline recommending the use of biomarkers to help manage Crohn’s disease. Biomarkers such as C-reactive protein and fecal calprotectin can measure levels of inflammation, helping doctors assess disease activity and guide treatment decisions.

SourceAmerican Gastroenterological Association·JournalGastroenterology·TypeSystematic review·DateNov 17, 2023

We achieved gender parity in astronomy in just five years

A national Australian astronomy centre achieved gender parity in just five years by implementing evidence-based strategies and creating a supportive culture. The Centre's program reached a tipping point when there were 40% women in leadership positions, resulting in accelerated student enrolments by women.

SourceARC Centre of Excellence for All Sky Astrophysics in 3D (ASTRO 3D)·JournalNature Astronomy·TypeExperimental study·DateNov 16, 2023

The Future of Future Earth: How global science programs can navigate the complex, shifting challenges in sustainability science

The Future Earth program has faced challenges in inspiring groundbreaking research to address major sustainability issues, including a lack of engagement with the global science community. The program's 'top-down approach' neglects local communities' needs and prevents swift responses.

SourceEcosystem Health and Sustainability·JournalEcosystem Health and Sustainability·TypeCommentary/editorial·DateNov 15, 2023

Ground-breaking discovery could pave the way for new therapies to prevent cardiovascular disease and stroke

Scientists at the University of Leicester have made a groundbreaking discovery about how cholesterol in our diet is absorbed into our cells. The research, published in Science, highlights the role of two proteins called Aster B and Aster C in transporting cholesterol from the intestine to the bloodstream.

SourceUniversity of Leicester·JournalScience·TypeExperimental study·DateNov 13, 2023

UTHealth Houston partners with Mexican organizations for $5 million NIH grant to improve implementation of cancer control interventions in Mexico and Latin America

The UTHealth Houston Institute for Implementation Science has received a five-year, $5 million grant from the National Cancer Institute to support research and training in implementation science. Researchers will focus on improving cancer control efforts in Mexico and Latin America.

Poor night’s sleep can trigger atrial fibrillation the next day

A new study by UC San Francisco found that poor sleep is significantly associated with a 15% greater risk of experiencing atrial fibrillation the next day. The researchers suggest strategies like going to bed at a reasonable time, avoiding alcohol and caffeine before bedtime, and exercising regularly to improve general sleep quality.

SourceUniversity of California - San Francisco·JournalJACC Clinical Electrophysiology·DateNov 3, 2023

Rafael De Cabo, Ph.D.(NIH), D.ing Xu, Ph.D. (UConn), and Claire K. Ankuda, MD, MPH, MSC (Mount Sinai Health System) to present lectures at AFAR Scientific Awards Ceremony

AFAR will host its annual Scientific Awards of Distinction lectures and ceremony on November 10 in Tampa, Florida, honoring Rafael de Cabo, Ming Xu, and Claire K. Ankuda for their contributions to aging research. The awardees will present lectures highlighting their research.

Parkinson disease and normal aging

Researchers investigate centro-cingulate network changes and cholinergic innervation deficits in Parkinson disease and normal aging. Studies reveal significant correlations between centro-cingulate changes and cognitive impairments, motor symptoms, and age.

SourceImpact Journals LLC·JournalAging-US·TypeCommentary/editorial·DateNov 1, 2023