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Researchers uncover NSMF protein’s role in relieving DNA replication stress

Researchers discovered NSMF protein's role in alleviating DNA replication stress by displacing weakly bound RPA proteins and promoting phosphorylation. This mechanism accelerates relief of replication stress, offering a new direction for treating various diseases, including cancer and age-related conditions.

Peering into nanofluidic mysteries one photon at a time

A team of researchers has developed an innovative approach to visualize individual molecule dynamics within nanofluidic structures using super-resolution microscopy and single-photon emitters. The study reveals new insights into the behavior of liquids on a nanometer scale, opening up exciting applications in optical imaging and sensing.

SourceUniversity of Manchester·JournalNature Materials·DateAug 31, 2023

MU researchers study barriers and facilitators to accessing health care in rural Missouri

A recent MU study found that health and healthcare organizations are increasingly offering basic social services, such as transportation, housing, food, and mental health support, to address disparities in health outcomes. The research team explored innovative solutions implemented by care coordinators and social services to help overc...

SourceUniversity of Missouri-Columbia·JournalProfessional Case Management·TypeSurvey·DateAug 28, 2023

Scientists invent new way to sort cells by type using light

Researchers have developed a new way to sort cells by type using light-based stimulated Raman spectroscopy, offering a label-free and nondestructive approach for various biomedical applications. The technique enables the separation of cells based on their intracellular chemical composition in high-throughput manner.

SourceOptica·DateAug 25, 2023

HKU Engineering team leads global collaboration for universal unit in environmental surveillance of antimicrobial resistance

The University of Hong Kong's research team has proposed a universal unit to standardize data sharing in antimicrobial resistance surveillance. This approach aims to enhance comparability across studies and facilitate globally coordinated efforts against antimicrobial resistance. The team's work has the potential to significantly chang...

SourceThe University of Hong Kong·JournalEnvironmental Science & Technology·TypeExperimental study·DateAug 13, 2023

Automated medical imaging framework revolutionizes schistosomiasis diagnosis

Researchers developed an innovative optical tool, the Schistoscope, to capture microscopy images of urine samples for efficient detection of Schistosoma haematobium eggs. A two-stage diagnostic framework using deep learning accurately identified and counted eggs in field settings with high sensitivity, specificity, and precision.

SourceSPIE--International Society for Optics and Photonics·JournalJournal of Medical Imaging·DateAug 7, 2023

Fact-checking can influence recommender algorithms

A Cornell University study found that encouraging fact-checking on Reddit led to a drop in story rank by an average of minus-25 spots, causing stories to be missed by readers. The research suggests that collective efforts to improve information environments can influence algorithmic recommendations.

SourceCornell University·JournalScientific Reports·DateAug 2, 2023

CHOP and Penn Medicine researchers develop “in vivo” RNA-based gene editing model for blood disorders

CHOP and Penn Medicine researchers have developed a proof-of-concept model for delivering gene editing tools directly into diseased blood cells within the body. This approach aims to reduce costs and increase access to gene therapies for blood disorders, which currently require chemotherapy and stem cell transplants.

New research explores durability of 2D hybrid materials

Researchers investigated the fatigue behavior of 2D hybrid organic-inorganic perovskites (HOIPs), discovering they can survive over one billion cycles, outperforming most polymers under similar loading conditions. The study provides insights into designing and engineering these materials for long-term mechanical durability.

SourceTexas A&M University·JournalAdvanced Science·DateJul 25, 2023

Researchers detail methodological approach to creating joint displays of data collection in mixed methods research

Researchers developed a step-by-step approach for creating joint displays of integrated data collection, facilitating comprehensive connections between qualitative and quantitative data. This method tackles the challenge of integrating qualitative and quantitative information in clinical studies, enabling robust mixed methods analysis.

SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateJul 25, 2023

Primary care clinics that improved patient access, identified at-risk patients and expanded services experienced reductions in acute hospitalizations

Researchers identified key strategies contributing to significant reductions in Medicare acute hospitalization rates at high-performing Comprehensive Primary Care Plus (CPC+) sites. These clinics implemented effective strategies such as improving timely access to primary care, identifying high-risk patients with enhanced care managemen...

SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateJul 25, 2023

Family loses child to necrotizing enterocolitis and publishes “Forever Our Little One,” a storybook for bereaved families

A mother-daughter duo has created a storybook to comfort bereaved families who have lost a child to necrotizing enterocolitis (NEC). The book, Forever Our Little One, features illustrations inspired by the family's experiences. The NEC Society will benefit from all sales, supporting research into the devastating intestinal disease.