The Louisiana Clinical & Translational Science Center has received a $1.3 million NIH grant to support the creation of a network of data warehouses for healthcare providers and researchers in Baton Rouge. The project aims to enhance research capacity, address health care disparities, and improve patient engagement.
Researchers discovered NSMF protein's role in alleviating DNA replication stress by displacing weakly bound RPA proteins and promoting phosphorylation. This mechanism accelerates relief of replication stress, offering a new direction for treating various diseases, including cancer and age-related conditions.
A three-year grant from the National Multiple Sclerosis Society will fund Dr. Carly Wender's study on maximizing learning and memory function in individuals with MS. The COMBINE intervention combines cognitive rehabilitation technique KF-mSMT with innovative exercise training to improve new learning and memory.
A panel of experts has defined clinical remission in asthma treatment, requiring six criteria met over 12 months. The definition aims to set an aspirational goal for prolonged control and optimize medication adherence.
Jessica Faulkner, a physiologist at the Medical College of Georgia, has been awarded the Harry Goldblatt Award from the American Heart Association's Hypertension Council. Her research focuses on the role of leptin in preeclampsia and obesity-associated cardiovascular disease in women.
A recent study found a three-fold increase in obesity-related heart disease deaths in the US between 1999 and 2020. The study highlights racial disparities, particularly among Black women, who faced the highest rates of obesity-related cardiovascular mortality.
Wogrin aims to improve data aggregation and create more meaningful models with the same computing power, resulting in suboptimal investment decisions and costly restructuring of energy systems. Her research approach takes into account different supply situations, enabling compressed and differentiated model data.
Researchers aim to identify genetic risk factors and mechanisms underlying virus-induced asthma, using artificial intelligence-based techniques and patient-derived models. The study may lead to personalized prevention campaigns and mechanism-targeted drugs.
A team of researchers has developed an innovative approach to visualize individual molecule dynamics within nanofluidic structures using super-resolution microscopy and single-photon emitters. The study reveals new insights into the behavior of liquids on a nanometer scale, opening up exciting applications in optical imaging and sensing.
A new study published in the Journal of the American Heart Association found that stressful life events and poor sleep are major contributing factors to irregular heart rhythms after menopause. The study analyzed data from over 83,000 women aged 50-79 and found a significant association between stress, insomnia, and atrial fibrillation.
A team of international scientists found that coral reefs, marshes, and mangroves could be destroyed within the next 30 years from rising sea levels. Coastal habitats are essential for protecting coastlines, trapping carbon, and supporting millions of coastal residents.
A new study found that people who received free produce prescriptions experienced increased fruit and vegetable consumption, leading to improved body mass index, blood sugar, and blood pressure levels. This research suggests that produce prescription programs may be an effective way to address food insecurity and promote health.
A recent MU study found that health and healthcare organizations are increasingly offering basic social services, such as transportation, housing, food, and mental health support, to address disparities in health outcomes. The research team explored innovative solutions implemented by care coordinators and social services to help overc...
Researchers have developed a new way to sort cells by type using light-based stimulated Raman spectroscopy, offering a label-free and nondestructive approach for various biomedical applications. The technique enables the separation of cells based on their intracellular chemical composition in high-throughput manner.
A study by Texas A&M University found that pregaming is linked to unsafe alcohol use and other risky behaviors among college students. Pregaming was associated with a two-day increase in alcohol use frequency and was found to be around 2.5 times more likely to lead to cannabis or other drug use.
A new dictionary provides a comprehensive overview of Shakespeare's language, revealing words with reduced mental ability and plant hybrids. The Arden Encyclopedia of Shakespeare's Language offers insights into the linguistic thumbprints of plays and characters, as well as the networks of character interaction.
Researchers found that certain anti-cancer compounds cause distinct nucleolar shapes and stress, which can be measured using a new classification system. This discovery could lead to improved understanding of why some drugs fail in clinical trials, providing a potential tool for identifying promising drug candidates.
The study found that individuals with hearing difficulties, vision impairments, and cognitive disabilities had the highest employment rates, with 52%, 40.3%, and 31.9% respectively. Remote work became essential during the pandemic, contributing to the surge in employment-to-population ratios for people with disabilities.
A new study finds SARS-CoV-2 infection significantly associated with development of high blood pressure in hospitalized adults. Persistent high blood pressure was more common in people with COVID-19 than influenza, highlighting potential long-term cardiovascular risk.
A new study found that a simple blood test can predict the risk of progressive heart and kidney disease in people with Type 2 diabetes. The test measures levels of four biomarkers, which fell after treatment with canagliflozin, a type 2 diabetes medicine.
The new Southern Center for Maternal Health Equity will develop innovative approaches to reduce pregnancy-related complications and deaths in the Gulf South. The center aims to promote maternal health equity and address disparities in maternal mortality rates, particularly among Black pregnant and postpartum people.
A recent study published in Neuron reveals that Noelin proteins play a crucial role in learning and memory formation in the mammalian brain. The study found that these proteins act as 'universal anchors' controlling the distribution and dynamics of AMPA receptors, which are essential for synaptic plasticity.
A new study published in the Journal of the American Heart Association found that people who experience pain after a heart attack are more likely to die within the next 8.5 years. The study analyzed data from over 18,300 adults who had a heart attack and found that moderate or extreme pain was linked to a higher mortality risk.
Researchers at Children's Hospital of Philadelphia developed TEQUILA-seq, a cost-effective technology for targeted long-read RNA sequencing. This innovation enables accurate accounting of all RNA molecules emanating from a single gene, crucial for understanding diseases like cancer.
A new scientific statement from the American Heart Association highlights the importance of shared decision-making in cardiovascular care. Key findings include improved patient understanding, acceptance, and satisfaction when healthcare teams involve patients in decision-making processes.
The University of Hong Kong's research team has proposed a universal unit to standardize data sharing in antimicrobial resistance surveillance. This approach aims to enhance comparability across studies and facilitate globally coordinated efforts against antimicrobial resistance. The team's work has the potential to significantly chang...
A multicenter study found that long COVID symptoms can emerge months after infection and persist for at least a year in about 16% of cases. The study highlights significant impacts the epidemic has had on the US healthcare system and emphasizes the need for further research into post-COVID conditions.
Researchers at West Virginia University are tracing the cause of diabetic heart disease using diabetic animal models to examine mitochondrial function. They hope to understand how faulty protein import affects the mitochondria and explore potential treatments to improve energy production and reduce cardiovascular risk.
A new study found consistent increases in premature cardiovascular disease (CVD) death and disability due to particulate matter air pollution globally. The analysis, published in the Journal of the American Heart Association, revealed a 8.1% rise in age-standardized CVD deaths attributed to outdoor PM pollution between 1990 and 2019.
The American Heart Association is funding three new scientific research projects to examine the use of race in formulas that calculate risk and determine treatment for cardiovascular disease. The teams will assess potential bias in risk models, develop statistical methods to correct algorithm bias, and support equitable care.
The Carnegie Mellon Portugal Program has selected six new exploratory projects in information and communication technologies, with over €350,000 in funding. The projects focus on various areas, including digital health, anxiety detection, and neural probes.
A £1.75m project led by Professor Chenyu Du aims to develop new processes for recovering polyester and cellulose from mixed cotton and polyester fibres. The goal is to create a roadmap towards net-zero for the textiles industry, reducing plastic waste and increasing recycling rates.
The study found that receiving videos or reminders increased consumption of media content about the issue, increased knowledge about available resources, and reported use of some resources in response to violence. However, long-term attitudes towards gender and marital equity remained unchanged.
A new American Heart Association science advisory emphasizes the need for more resources and best practices in pediatric preventive cardiovascular care. The survey found that many programs are overwhelmed with referrals and have long wait times, highlighting the importance of updated guidelines and strategic action plans.
Researchers developed an innovative optical tool, the Schistoscope, to capture microscopy images of urine samples for efficient detection of Schistosoma haematobium eggs. A two-stage diagnostic framework using deep learning accurately identified and counted eggs in field settings with high sensitivity, specificity, and precision.
A recent study discovered the complex circadian clock mechanisms in soil bacteria Bacillus subtilis, regulating multiple genes and behaviors. The findings have significant implications for industrial applications, human health, and plant science.
The July 2023 nTIDE report shows that people with disabilities maintained their job numbers and achieved an all-time high employment level of 37.3%. The labor force participation rate for people with disabilities increased by 8.3% from last year, reaching 40.4%, while the employment-to-population ratio rose to 37.3%.
The GEMINI blood test uses machine learning to identify cancer-causing mutations in single molecules of cell-free DNA. The test detected over 90% of lung cancers, including stage I and II cases, in a proof-of-concept study published in Nature Genetics.
UK researchers have developed an evidence-based action plan to address the substantial under-representation of PhD students from ethnic minority backgrounds in postgraduate science studies. The study highlights three areas for improvement: student-facing improvements, admissions procedures, and evaluation processes.
A Cornell University study found that encouraging fact-checking on Reddit led to a drop in story rank by an average of minus-25 spots, causing stories to be missed by readers. The research suggests that collective efforts to improve information environments can influence algorithmic recommendations.
Researchers aim to investigate the link between gut microbes and Type 1 diabetes. Emrah Altindis's lab seeks to understand how a protein found in certain bacteria may trigger the onset of T1D.
The Global Atlas of Literacies for Health (GALH) is an interactive map displaying levels of health literacy and digital health literacy from evidence-based studies. The atlas provides a critical tool for literacy reform, enabling targeted interventions for marginalized groups.
CHOP and Penn Medicine researchers have developed a proof-of-concept model for delivering gene editing tools directly into diseased blood cells within the body. This approach aims to reduce costs and increase access to gene therapies for blood disorders, which currently require chemotherapy and stem cell transplants.
Researchers investigated the fatigue behavior of 2D hybrid organic-inorganic perovskites (HOIPs), discovering they can survive over one billion cycles, outperforming most polymers under similar loading conditions. The study provides insights into designing and engineering these materials for long-term mechanical durability.
A Canadian study found that patients were very satisfied with care from their family physicians (90%) and allied health teams (89%), comparable to traditional in-person models. Another pilot program successfully engaged hard-to-reach adolescents in preventive care, demonstrating a 40% increase in show rates for well visits.
The study used electronic health record data from over 200,000 children to describe patterns of pediatric allergies across the US, validating the 'allergic march' pattern. It also found that eosinophilic esophagitis (EoE) is more common among non-White patients than previously reported.
Researchers developed a step-by-step approach for creating joint displays of integrated data collection, facilitating comprehensive connections between qualitative and quantitative data. This method tackles the challenge of integrating qualitative and quantitative information in clinical studies, enabling robust mixed methods analysis.
Researchers identified key strategies contributing to significant reductions in Medicare acute hospitalization rates at high-performing Comprehensive Primary Care Plus (CPC+) sites. These clinics implemented effective strategies such as improving timely access to primary care, identifying high-risk patients with enhanced care managemen...
A mother-daughter duo has created a storybook to comfort bereaved families who have lost a child to necrotizing enterocolitis (NEC). The book, Forever Our Little One, features illustrations inspired by the family's experiences. The NEC Society will benefit from all sales, supporting research into the devastating intestinal disease.
Researchers found that post-menopause females have lower incidence of tooth marks in their social unit, implying they may be protecting their sons from conflict. This suggests a new pathway for the adaptability of menopause in killer whales.
Researchers at Children's Hospital of Philadelphia found that NSAIDs exacerbate C. difficile infections by disrupting epithelial cell mitochondria, sensiting them to toxins. The study shows that NSAIDs and C. difficile toxins work synergistically to increase virulence, leading to increased disease severity and mortality.
A recent study found that women with Lyme disease experience longer diagnostic delays, more severe symptoms, and increased misdiagnoses compared to men. The study also revealed no significant differences in antibiotic treatment response or side effects.
The Biodiversity Knowledge Hub (BKH) is a one-stop portal providing access to FAIR biodiversity data and services. It enables researchers to navigate linked data, tools, and services across the entire biodiversity research cycle.
A new study published in Circulation journal found that Black adults living in areas historically affected by discriminatory housing practices had a higher heart failure risk. The analysis included over 2.3 million adults from 2014-2019 and mapped historical redlining maps onto modern day maps of US zip codes.
A national estimate suggests that 795,000 Americans die or are permanently disabled by diagnostic error each year. The top causes of serious harm include stroke, sepsis, and pneumonia.
Research reveals e-cigarettes carry potential health risks, including increased blood pressure and heart rate. Long-term studies are needed to fully understand the effects of e-cigarette use on the heart and lungs.
A study reveals high levels of insecticide resistance among Aedes aegypti populations in Dhaka, compromising mosquito control and increasing dengue burden. Researchers recommend non-insecticidal approaches, such as Wolbachia-infected mosquitoes, to effectively manage dengue vectors.
Fetuses use a copy of a gene inherited from their dad to force their mum to release as much nutrients possible during pregnancy. This 'remote-control' system is operated by genes that can be switched on or off depending on whether they are a 'dad's' or 'mum's' gene.
Prof. Dr. Marta Litter takes over as Editor-In-Chief of Journal of Photocatalysis, bringing her extensive expertise and experience to lead the journal into a new era of excellence. Her research on heterogeneous photocatalysis and iron-based nanomaterials has led to over 250 scientific publications.
Researchers at the University of Virginia Health System have identified a novel mechanism by which hair cells can repair themselves after damage. This breakthrough understanding has the potential to develop new treatments for age-related hearing loss and other conditions.