Researchers found that blocking dopamine transporters during mid-adolescence increases adult aggression, impulsivity, and the behavioral response to amphetamine in mice. Artificially stimulating dopaminergic neurons also exacerbated impulsive behavior in tasks. The study suggests potential harm from stimulant exposure in healthy teens ...
SourceColumbia University Irving Medical Center·JournalMolecular Psychiatry·TypeObservational study·DateAug 2, 2023
Researchers propose disease-oriented dosing of rapamycin to delay age-related diseases and increase lifespan. By decelerating early development of these diseases, rapamycin may help individuals live longer.
SourceImpact Journals LLC·JournalAging-US·TypeCommentary/editorial·DateAug 2, 2023
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A large cohort study found that a low intake of dietary fiber during pregnancy is associated with neurodevelopmental delays in children. The study analyzed data from over 76,000 mother-infant pairs and found that children of mothers who consumed less fiber were more likely to show delays in brain function development.
SourceFrontiers·JournalFrontiers in Nutrition·DateJul 27, 2023
A new study published in Aging (Albany NY) suggests that prior training can rescue cognitive decline in aging by improving task performance and strengthening memory processes. The research, conducted on rats, found that prior training enhanced short-term and intermediate memory, while also enabling encoding-boosted long-term memory.
SourceImpact Journals LLC·JournalAging-US·TypeExperimental study·DateJul 19, 2023
Researchers identified significant differences between individuals with CHAMP1 coding mutations and deletions, affecting adaptive functioning skills and severity of symptoms. The study highlights the importance of understanding genetic mechanisms to develop precision medicine approaches for treating CHAMP1 disorder.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalHuman Genetics·TypeObservational study·DateJul 17, 2023
The study found an association between COVID-19 pandemic exposure and delayed childhood development in children aged 5. Variations in development widened during the pandemic, regardless of age, emphasizing the importance of identifying and supporting affected children.
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Residents of southern Israel suffered significantly greater physiological and mental harm than others, with spikes in heart rate and stress, reduced sleep duration, and decreased physical activity. Women, young people, and those living near Gaza paid the heaviest price, with notable differences in screen time, mood, and quality of sleep.
SourceTel-Aviv University·JournalCommunications Medicine·DateJul 4, 2023
Researchers develop an ionic device utilizing redox reactions to achieve a high number of reservoir states, enabling efficient complex nonlinear operations. The device demonstrated remarkable performance in solving second-order nonlinear dynamic equations and predicting future values with low mean square prediction error.
SourceTokyo University of Science·JournalAdvanced Intelligent Systems·TypeExperimental study·DateJul 3, 2023
Researchers at Tel Aviv University have developed an innovative gene therapy that shows promise in treating Dravet syndrome, a severe developmental epilepsy affecting children. The treatment was found to be effective in improving epilepsy, protecting against early death, and enhancing cognitive abilities.
SourceTel-Aviv University·JournalJournal of Clinical Investigation·DateJun 22, 2023
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers found that the amyloid precursor protein (APP) regulates human neurogenesis, which could be linked to Alzheimer's disease. APP promotes a balance between stem cell proliferation and differentiation, suggesting its disruption may cause premature neurogenesis and cellular stress.
SourceInstitut du Cerveau (Paris Brain Institute)·JournalScience Advances·TypeExperimental study·DateJun 16, 2023
The study reveals that spontaneous waves of neurotransmitter glutamate facilitate dendrite pruning, while a unique protection/punishment machinery strengthens certain connections and eliminates others. Proper pruning is critical for neural development, with insufficient or excessive connections linked to neurophysiological disorders.
SourceKyushu University·JournalDevelopmental Cell·TypeExperimental study·DateJun 7, 2023
Researchers have developed a simple blood test that can diagnose De Vivo disease, a rare and disabling neurological disorder. The test, called METAglut1, has a high sensitivity and specificity, allowing for accurate diagnosis in a short amount of time.
SourceInstitut du Cerveau (Paris Brain Institute)·JournalNeurology·TypeRandomized controlled/clinical trial·DateJun 5, 2023
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A team of researchers from UNIGE and Beihang University has identified the FOXI3 gene as responsible for one form of Goldenhar syndrome, a rare congenital disorder. Pathogenic variants in both copies of the FOXI3 gene are necessary for the disease to develop, following an autosomal recessive inheritance pattern.
SourceUniversité de Genève·JournalNature Communications·TypeNews article·DateMay 4, 2023
A UToledo-led study found early exposure to pyrethroids may increase the risk of autism and developmental disorders in mice. The researchers discovered behavioral changes, including hyperactivity and repetitive behaviors, which are similar to symptoms seen in human patients with neurodevelopmental disorders.
SourceUniversity of Toledo·JournalPNAS Nexus·DateApr 25, 2023
A new study from the University of East Anglia found that children with larger vocabularies look quickly towards objects when learning new words, while those with smaller vocabularies take more time and look back and forth. The research team hopes to identify children at risk for language delay earlier and provide targeted support.
SourceUniversity of East Anglia·JournalDevelopmental Science·TypeObservational study·DateApr 18, 2023
A nationwide UK research study has diagnosed around 5,500 children with severe developmental disorders, identifying the genetic cause of their condition. The Deciphering Developmental Disorders study used genomic sequencing technology to provide diagnoses for families from across the UK and Ireland.
SourceUniversity of Exeter·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateApr 12, 2023
Researchers have linked higher lithium levels in drinking water to a moderately higher risk of autism spectrum disorder in offspring. The study found that mothers living in urban areas had a slightly stronger association between lithium exposure and autism risk.
SourceUniversity of California - Los Angeles Health Sciences·JournalJAMA Pediatrics·DateApr 3, 2023
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers at Texas A&M University have developed the first molecular therapeutic for Angelman syndrome, a devastating neurogenetic disorder. The therapy targets an evolutionarily conserved region in the UBE3A-AS transcript and has shown promising results in clinical trials.
SourceTexas A&M University·JournalScience Translational Medicine·DateMar 22, 2023
Researchers say parents' well-intentioned efforts to protect children from harm have inadvertently deprived them of independence and opportunities for self-directed play. This decline in 'child's play' is linked to rising anxiety, depression, and suicide rates among school-aged children.
SourceFlorida Atlantic University·JournalThe Journal of Pediatrics·TypeObservational study·DateMar 9, 2023
A Keck School of Medicine study found exposure to PFAS, known as 'forever chemicals,' disrupts key biological processes in children and young adults, increasing risk of diseases such as developmental disorders, cardiovascular disease, and cancer. The study highlights the importance of regulating PFAS as a class of chemicals.
SourceKeck School of Medicine of USC·JournalEnvironmental Health Perspectives·TypeExperimental study·DateFeb 22, 2023
Researchers developed a new imaging technique revealing abnormal circulation patterns of brain fluid in developing brains. Disruptions to cerebrospinal fluid flow may underlie cognitive deficits and developmental delays in conditions like hydrocephalus.
SourceWashU Medicine·JournalNature Communications·TypeExperimental study·DateFeb 9, 2023
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
A germline mutation of topoisomerase II B affects the movement of proteins in the nuclei of cells with this mutation. The study reveals that the mutation impacts nuclear dynamics and provides a platform to understand the biological relevance of such mutations.
SourceKumamoto University·JournalScientific Reports·TypeExperimental study·DateJan 18, 2023
Internet-delivered parent-child interaction therapy shows promise in expanding care for underserved children with developmental delay. The study found significant improvements in child behavior that were maintained across follow-up visits.
SourceJAMA Network·JournalJAMA Pediatrics·DateJan 9, 2023
Researchers identified the molecular mechanism underlying Weiss-Kruszka syndrome, a rare neurodevelopmental disorder characterized by craniofacial anomalies and autistic features. The study reveals that the ZFP462 gene mutation leads to a failure to safeguard neural lineage specification during early embryonic development.
SourceIMBA- Institute of Molecular Biotechnology of the Austrian Academy of Sciences·JournalNature Cell Biology·TypeExperimental study·DateJan 5, 2023
Research published in Developmental Medicine & Child Neurology reveals a link between maternal diabetes and neurodevelopmental disorders such as autism, ADHD, and intellectual disability in children. Type 1 and type 2 diabetes were associated with increased risks of these conditions, while gestational diabetes was linked to autism spec...
SourceWiley·JournalDevelopmental Medicine & Child Neurology·DateDec 21, 2022
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers have discovered physical forces and hydrodynamic flows that ensure proper functioning of life's blueprint. The study provides insights into the genome's organization and function, shedding light on its biophysical origins. This knowledge is crucial for understanding genetic disorders and human diseases.
SourceNew York University·JournalPhysical Review X·TypeComputational simulation/modeling·DateDec 19, 2022
Researchers use novel interferometric technique to measure time delay between H2 and D2 isotopes, finding phase shift of nearly 3 attoseconds caused by nuclear motion. The study uses high harmonic generation and advanced theoretical modeling to validate the method.
SourceUltrafast Science·JournalUltrafast Science·TypeExperimental study·DateDec 15, 2022
A study of 2 million births found maternal unintentional injury during pregnancy increases risk of cerebral palsy. Children exposed to maternal injuries that resulted in hospitalization or preterm delivery are at higher risk.
A Rutgers-led study found that a gene mutation associated with autism causes an overstimulation of brain cells, disrupting the normal information flow. The researchers used human stem cells and transplanting them into mouse brains to understand how the mutation affects brain development.
SourceRutgers University·JournalMolecular Psychiatry·TypeExperimental study·DateNov 21, 2022
A new study by University of Wisconsin-Madison professor Andre Sousa investigates the differences and similarities of cells in the prefrontal cortex between humans and non-human primates. The researchers found five cell types unique to humans and differences in cell abundance across species.
SourceUniversity of Wisconsin-Madison·JournalScience·TypeObservational study·DateNov 8, 2022
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A study published in JAMA Pediatrics found that developmental-behavioral pediatricians can diagnose most autism cases in young children without ADOS testing. In 90% of cases, the ADOS results did not change the original clinical diagnosis, suggesting that DBPs can accurately assess ASD symptoms.
SourceBoston Children's Hospital·JournalJAMA Pediatrics·DateOct 27, 2022
A recent study at the Max Planck Institute for Human Cognitive and Brain Sciences found that mothers' postnatal depressive moods can impact their babies' ability to distinguish speech sounds. Mothers in a negative mood tend to use less infant-directed speech, leading to delayed language development in infants.
SourceMax Planck Institute for Human Cognitive and Brain Sciences·JournalJAMA Network Open·TypeExperimental study·DateOct 7, 2022
Researchers analyzed data from 145,000 pregnancies and found that antidepressant exposure was not associated with autism spectrum disorder or other neurodevelopmental disorders. The study suggests that antidepressant use during pregnancy may not increase the risk of these conditions in children.
SourceJAMA Network·JournalJAMA Internal Medicine·DateOct 3, 2022
A study by Brigham Young University found that parent-led interventions significantly improve social and communication skills in children with autism spectrum disorder. The meta-analysis of over 50 studies included 2,895 child participants who received about 90 minutes of intervention training each week.
SourceBrigham Young University·JournalJournal of Autism and Developmental Disorders·TypeMeta-analysis·DateSep 6, 2022
A study found that genetic testing before pregnancy can detect the risk of severe developmental disorders in 44% of cases if parents are related. However, non-hereditary mutations play a larger role in children of non-consanguineous couples, and many genes remain undetected.
SourceUniversity of Zurich·JournalGenomic Medicine·TypeExperimental study·DateAug 30, 2022
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers identified a molecule produced by astrocytes that interferes with normal neuron development in Rett, fragile X and Down syndromes. Blocking this molecule reduces disease signs in mice brains, suggesting potential therapeutics to treat these disorders.
SourceSalk Institute·JournalNature Neuroscience·DateAug 30, 2022
A new study of over 150,000 participants has identified more than 70 genes strongly associated with autism and over 250 with strong links to the condition. The analysis provides insights into the molecular roots of brain development and neurodiversity.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNature Genetics·TypeData/statistical analysis·DateAug 18, 2022
Children with complex congenital heart defects are 5 times more likely to receive an anxiety diagnosis, highlighting the need for mental health assessment and treatment. For adults, 50% experience mood or anxiety disorders, underscoring the importance of integrated mental health care in CHD specialty teams.
SourceAmerican Heart Association·JournalCirculation·DateJul 14, 2022
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A new genetic disease has been identified that causes abnormal brain development in children, resulting in severe learning difficulties. Researchers have discovered the underlying cause of the condition by analyzing changes in a protein coding gene called GRIA1, which helps move electrical signals around the brain.
SourceUniversity of Portsmouth·JournalAmerican Journal of Human Genetics·TypeExperimental study·DateJun 24, 2022
A survey study examined sociodemographic factors influencing the association between neurodevelopmental disorders and bullying. The study found that certain factors, such as socioeconomic status and parental education, may modify this association.
SourceJAMA Network·JournalJAMA Pediatrics·DateJun 6, 2022
Researchers have developed a new tool to visualize leukocytes in the brain vasculature during in vivo two-photon laser scanning microscopy. The tool uses a fluorescent antibody targeting CD45, a ubiquitously expressed protein on white blood cells, allowing for tracking of circulating leukocytes over time and space.
SourceSPIE--International Society for Optics and Photonics·JournalNeurophotonics·DateMay 25, 2022
A new study from Keck Medicine of USC found that cochlear implants improve deaf children's cognitive, adaptive behavior, language, and auditory skills, regardless of developmental impairments. The study suggests that deaf children with learning delays should receive cochlear implants to reach their full potential.
SourceUniversity of Southern California - Health Sciences·JournalPEDIATRICS·TypeObservational study·DateMay 24, 2022
A study found a connection between learning and memory deficits in children with Joubert Syndrome and defects in the hippocampus. The researchers used animal models to create a genetic mutation that mimicked the human disease, revealing key findings about the role of primary cilia in brain development.
SourceUniversity of Bath·JournalHuman Molecular Genetics·TypeExperimental study·DateMay 10, 2022
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A proof-of-concept study suggests that postnatal gene therapy may prevent or reverse deleterious effects of Pitt-Hopkins syndrome, a rare genetic disorder. The treatment restored normal activity of the deficient gene, preventing anxiety-like behavior and memory problems in an animal model.
SourceUniversity of North Carolina Health Care·JournaleLife·TypeExperimental study·DateMay 10, 2022
A study led by Kobe University researchers found that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells, leading to immune dysregulation and brain-gut axis disorders. The study used BTBR mice as a model and identified histone deacetylase HDAC1 as a common mechanism underlying these pathologies.
SourceKobe University·JournalMolecular Psychiatry·TypeExperimental study·DateMay 1, 2022
Researchers have discovered 15 genomic loci that either accelerate or decelerate brain aging, offering potential new drug targets to combat Alzheimer's disease and other degenerative brain disorders. The study, led by USC researchers, found overlap with genes involved in depression, schizophrenia, and cognitive functioning.
SourceUniversity of Southern California·JournalNature Neuroscience·TypeData/statistical analysis·DateApr 5, 2022
H. Alex Choi receives NIH grant to develop protein biomarkers for delayed cerebral ischemia, a complication after subarachnoid hemorrhage that affects approximately 50,000 Americans annually. The goal is to predict which patients will worsen and identify biological processes causing worsening patients.
SourceUniversity of Texas Health Science Center at Houston·DateMar 30, 2022
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
A recent study found that approximately 1 in 3 heart attack survivors experience significant mental decline in the days and months following their heart attack. Cognitive deficits can impact quality of life and treatment adherence, emphasizing the need for cardiologists to monitor patients regularly.
The collaboration aims to prepare professionals to support school-aged students with autism spectrum disorder and related disabilities. Full scholarships will be awarded to 24 graduate students starting in Fall 2022.
SourceUniversity of Massachusetts Lowell·DateMar 2, 2022
A new study found that siblings of children with disabilities score higher in self-reported cognitive empathy than typically developing peers. This may be due to the specific 'advantage' of cognitive empathy in understanding and supporting their sibling relationship.
SourceThe Hebrew University of Jerusalem·JournalChild Development·TypeObservational study·DateFeb 23, 2022
Researchers have identified a key brain protein to target for new customized drug therapies treating adverse symptoms of developmental disorder subtypes. The study found that mutations in ARHGEF9 lead to intellectual disability through impaired α2 subunit function, which is a central hub for many neurological symptoms.
SourceUniversity of Nevada, Las Vegas·JournalNature·DateFeb 22, 2022
A study published in Human Reproduction found that smoking by mothers during the periconceptional period is associated with delayed embryonic development, smaller foetuses at the 20-week ultrasound scan, and lower birth weights. The delay in embryonic development was found to have a greater impact in the second trimester of pregnancy.
SourceEuropean Society of Human Reproduction and Embryology·JournalHuman Reproduction·TypeObservational study·DateFeb 22, 2022
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers found that blocking an overactive signaling pathway during the first five weeks of life prevents autism symptoms from developing in mice. The study suggests that targeting this critical period could lead to a potential cure for autism.
SourceSociety for Neuroscience·JournalJNeurosci·TypeExperimental study·DateFeb 21, 2022
Researchers found high levels of per- and polyfluorinated alkyl substances (PFAS) in anti-fogging sprays and cloths sold on Amazon. The products contained fluorotelomer alcohols and fluorotelomer ethoxylates, which are associated with impaired immune function, cancer, and other health disorders. The study highlights the need for more r...
SourceDuke University·JournalEnvironmental Science & Technology Letters·TypeExperimental study·DateJan 5, 2022
Research by University of Texas Health Science Center at San Antonio scientists found that mice missing one copy of the Tbx1 gene exhibit slower cognitive processing. The gene's deletion led to diminished myelin insulation around nerves, impacting signal conduction between brain regions.
SourceUniversity of Texas Health Science Center at San Antonio·JournalMolecular Psychiatry·TypeExperimental study·DateDec 21, 2021
Researchers found that a genetic mutation associated with severe congenital epilepsy also leads to neural degeneration, inflammation and behavioral symptoms in mice. The study suggests the mutation as a potential target for treatment.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateDec 17, 2021
Children with congenital zika syndrome exhibit different neurological development profiles, with varying abilities to respond to stimuli. Larger head circumference is associated with higher cognitive and motor scores, according to the study published in PLOS ONE.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalPLOS ONE·DateDec 13, 2021
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers from UNIGE found that a single missing genetic switch can lead to clubfoot and other malformations by disrupting cellular activation. The study highlights the crucial role of genetic switches in developmental disorders, suggesting that flaws in these mechanisms may be responsible for numerous malformations.
SourceUniversité de Genève·JournalNature Communications·TypeExperimental study·DateDec 13, 2021
A new study by researchers at Mount Sinai found that a specific gene, HHIP, helps regulate the development of the coronal suture, a fibrous joint that connects the front and middle bone plates. The study showed that embryos with a missing HHIP gene had misshapen skulls and fewer mesenchymal cells separating the bones.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNature Communications·TypeExperimental study·DateDec 9, 2021
Children with autism benefit from group-based weight management and family-centered nutrition education, which improves eating habits and exercise motivation. The program's success rate is higher among families who complete the entire program, indicating its potential as an adjunct or alternative to traditional interventions.
SourceElsevier·JournalJournal of Nutrition Education and Behavior·TypeObservational study·DateDec 8, 2021