Research from the field of mental-health medicine. Covers diagnostic agreement, youth psychiatric emergencies, schizophrenia genetics, and clinical leadership.
A study by Johns Hopkins Medicine researchers found that more than 85% of tested CBD products contained inaccurate labeling, including misstated CBD amounts and presence of THC. The study also revealed that some products made unapproved therapeutic claims, highlighting the need for better regulatory oversight.
A new study finds that racial discrimination affects brain microstructure, increasing the risk for health disorders in Black women. Traumatic experiences lead to changes in brain white matter tracts, which may enhance risk for negative health outcomes.
A recent study published in Frontiers found that older patients respond equally well to rTMS but with slower onset of effects compared to younger patients. The researchers suggest revising treatment protocols to consider longer courses for older adults, making this treatment more accessible.
A comprehensive review of research on serotonin and depression found no link between the two, contradicting long-held theories. The study suggests that antidepressants' effectiveness may be due to managing stressful life events rather than correcting chemical imbalances.
A new study found that individual details of a memory are parsed and stored elsewhere, in the prefrontal cortex. This separation ensures that exposure to any cue is sufficient to activate the prefrontal cortex for recall of the whole memory.
A study by University of Florida researchers found that gardening lowered stress, anxiety, and depression in healthy women attending twice-weekly gardening classes. The participants experienced similar improvements in mental health as those in art-making sessions, with gardeners reporting slightly less anxiety.
A UC San Diego study reveals six overarching themes contributing to physician job stress and suicide, including physical health deterioration and financial stress. The research calls for short-term solutions like improved access to primary care and long-term changes to address workplace culture and self-care.
A new IU screening tool, Convergent Functional Information for Suicidality (CFI-S), has been validated to predict 80-90% of future suicidality. The tool identifies top risk factors such as feeling useless or unneeded, history of suicidality, and social isolation.
Patients experiencing dissociative symptoms after trauma may be at high risk of developing severe post-traumatic stress, depression, anxiety, and social impairment. Early interventions are crucial for these individuals.
A new study reveals that police involvement in student mental health transfers at Ontario universities differs significantly, with some universities using handcuffs routinely and others reserving them for rare circumstances. The study recommends engaging police only in high-risk situations to minimize restraints during transfers.
A new study suggests that losing a grandmother may have a significant impact on adolescent boys, leading to a 50% increase in depressive symptoms. The researchers also found that the loss of a grandparent can be a risk factor for teen depression and other negative outcomes.
A new study by an international group of researchers has found substantial reductions in grey matter in people with anorexia nervosa, a condition characterized by severe food restriction and low body weight. Early intervention and treatment can help the brain repair itself, according to the research team led by Dr. Paul M. Thompson.
Researchers analyzed data from 599 patients with premenstrual dysphoric disorder and found that 34% have attempted suicide, with high rates of suicidal ideation, planning, and self-injury among women. The study highlights the need for accurate diagnosis and screening of suicidal ideation in patients with PMDD.
Women with self-injury behaviour show a more effective pain-modulation system, displaying more connections between pain perception and modulation brain areas. This finding suggests that effective pain modulation is a risk factor for self-injury behaviour, providing valuable insights for improving treatment and support.
A major study of nearly 2,000 brain scans found significant reductions in cortical thickness, subcortical volumes, and cortical surface area in individuals with anorexia. Early treatment and weight gain were shown to positively impact brain structure, suggesting the potential for long-term recovery.
Researchers at Rutgers University found that cannabis users tend to overestimate their ability to manage conflict in romantic relationships and may overlook unhealthy dynamics. The study suggests that couples who use cannabis can benefit from better navigating conflict discussions and resolution.
A new study shows that hospice patients with dementia receive excellent care and have their anxiety and sadness managed more often than those without dementia. However, the Medicare hospice model's limitations can lead to gaps in care, leaving patients with dementia at risk of disenrollment.
A new study finds that women using hormonal contraceptives have lower rates of attempted suicides compared to those who do not use them. The research, published by the European Psychiatric Association, analyzed data from over 587,000 Finnish women and found a significant reduction in suicide attempts among hormonal contraceptive users.
A new study has found that people who believe in COVID-19 conspiracy theories are more likely to experience severe anxiety and depression. The research, published in Frontiers in Psychiatry, used a scale to measure belief in conspiracy theories and found a significant correlation with increased symptoms of anxiety and depression.
Babies born to mothers infected with COVID-19 show differences in motor function and relaxation, especially when held. Preliminary analysis suggests increased risk of neurodevelopmental changes compared to uninfected babies.
Physicians recognize benzodiazepine dependence as a significant contributor to the opioid crisis, coined a new term CPBD. Long-term treatment can lead to severe withdrawal symptoms and recurrence of underlying anxiety and insomnia.
The June issues of The American Journal of Psychiatry and Psychiatric Services address mental health disparities and structural racism. These journals provide a platform for collaborative responses to behavioral health emergencies, shedding light on important topics in the field.
A decade-long effort to reduce medication risks for nursing home residents with dementia has shown some positive results, but also unintended consequences. Fewer people are receiving antipsychotic and anti-anxiety drugs, which can raise the risk of falling or dying, but more are receiving alternative behavior-changing medications with ...
The June special issue highlights the impact of structural racism on mental health and proposes community-wide interventions to address disparities. Research prioritization is also discussed to advance mental health inequity research.
Early treatment with psychotropic medications in children and adolescents significantly reduces the risk of developing a substance use disorder (SUD) by 30-35% for ADHD and major depressive disorder. Longer treatment durations also show positive results, especially when initiated before age nine.
A new study from Aarhus University and Aarhus University Hospital – Psychiatry has found that Danish patients with mental disorders experienced a worsening of symptoms in connection with the invasion of Ukraine. The study analyzed over 500,000 clinical notes from psychiatric hospitals in Denmark and identified a sharp increase in clini...
A new study found that statin users were less likely to recognize fearful faces and more likely to report them as positive, indicating reduced negative emotional bias. Statins may provide protection against depression through their effect on emotion processing, possibly due to anti-inflammatory mechanisms.
A new study reveals massive variations in hospice medication prescriptions, with treatment agency being the primary factor. Patients in agencies with high prescription rates were up to 50 times more likely to receive benzodiazepines or antipsychotics.
A large study has found six predictors that can help determine the optimal lithium dose for patients with bipolar disorder. The predictors include age, sex, kidney function, and medication use. The researchers hope to develop a digital app to aid psychiatrists in finding the right dose.
A study published in Journal of Psychiatric Research found a significant biological difference between psychopaths and non-psychopaths, with psychopaths having a larger striatum region in the brain. This finding is linked to increased need for stimulation, impulsive behaviors, and higher likelihood of violent behavior.
Rates of postpartum depression symptoms increased nationwide during the pandemic, reaching a high of 7.7% in December 2020 to March 2021. States with fewer COVID-19 deaths and lower unemployment rates showed greater increases in symptoms, likely due to reduced access to support systems.
Researchers developed a new model to understand how delusions emerge and are shaped by different contexts, revealing common themes across patient accounts. Clinicians must go beyond 'correcting' dysfunction to devise treatment that is relevant to the individual's emotions, life experiences, and socio-cultural contexts.
Researchers at the University of South Florida conducted a comprehensive review of data on 25,000 Canadians and found that long-term well-being is a realistic goal for some patients with mental illnesses. The study revealed that symptoms only correlate modestly with well-being, and that earlier treatment may improve outcomes.
A machine-learning model developed by researchers at Massachusetts General Hospital predicts which US Army soldiers are at greatest risk of homelessness upon transitioning to civilian life. The study identifies lifetime depression, trauma, and PTSD as key predictors, allowing for targeted interventions to mitigate homelessness.
The May issues of American Psychiatric Association journals explore the cognitive impacts of long-term cannabis use, the intersection of climate change and mental health, and tools to address children's mental health. The American Journal of Psychiatry and Psychiatric Services feature research reports on these topics.
A study led by Kobe University researchers found that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells, leading to immune dysregulation and brain-gut axis disorders. The study used BTBR mice as a model and identified histone deacetylase HDAC1 as a common mechanism underlying these pathologies.
A new study by Weill Cornell Medicine investigators found that adult vaccination rates and social determinants of health impacted children's mental health during the pandemic. Stress surrounding the pandemic decreased in children after vaccinations were rolled out for adults in December 2020.
A randomized clinical trial found that micronutrient supplementation improved attention and mood in children with ADHD, with a 54% response rate compared to 18% in the placebo group. The study also showed significant growth benefits in children taking the supplement.
A new Cochrane Review paper reveals that talk therapy can alleviate depression and improve quality of life for people with dementia. The study found that psychological interventions, such as Cognitive Behavioural Therapy (CBT), are effective in reducing symptoms of depression and improving wellbeing.
A cross-racial study of 1.87 million US veterans found significant differences in dementia incidence across five racial groups, with Hispanic and Black veterans at highest risk. Rates were significantly higher for Hispanics (99%) and Blacks (55%), while Asian veterans showed a 24% increase compared to whites.
Researchers found a clear link between elevated amyloid beta levels and the development of anxiety and apathy in Alzheimer's patients. These symptoms occur mainly due to underlying brain changes, not psychological reactions. The study suggests that psychiatric symptoms could be used as alternative outcome measures in treatment trials.
A University of Cincinnati study found that socioeconomic factors have a significant impact on depression treatment outcomes. Patients with lower incomes, less education, and minority backgrounds tend to have worse treatment outcomes even when receiving equal access to treatment.
A new study found that people with psychiatric conditions, especially those over 65, have a higher risk of breakthrough COVID. The researchers tracked data from over 250,000 VA patients and found increased risks for breakthrough infections among those with substance abuse, psychotic disorders, bipolar disorder, adjustment disorder, and...
A recent study found that structural racism and COVID-19 pandemic stressors are significantly associated with postpartum depression and anxiety among Black individuals. The study, published in JAMA Psychiatry, analyzed data from a large birthing cohort and found that participants who experienced worse pandemic-related worries, interper...
A new UC San Francisco study found that nearly half of young adults had mental health symptoms during the pandemic, with many unable to access therapy. The study highlights the importance of addressing barriers to care, including cost, stigma, and confidentiality concerns.
A new study by UC San Francisco and Imperial College London found that psilocybin therapy reduces connections within brain areas tightly connected in depression, while increasing connections to other regions. This leads to improved depressive symptoms and better cognitive functioning in participants.
The BrainChart platform benchmarks brain development based on MRI data from over 100,000 individuals, creating a standardized chart like those for height and weight. The tool identifies previously unreported neurodevelopmental milestones and provides a common language to understand brain images from different sources.
A new study by UCLA researchers found that a specialized primary care medical home improved the care and treatment of patients with serious mental illness, resulting in better mental health-related quality of life. The patient-centered medical home model provided comprehensive, coordinated care among patients and their clinicians, lead...
Researchers found that maternal post-traumatic stress disorder (PTSD) severity in early childhood predicts child somatisation at school age. The study highlights the importance of considering family trauma history in pediatric consultations to improve patient care.
A recent study published in Translational Psychiatry found that pharmacogenetic testing significantly improved symptoms in patients with treatment-resistant depression. The study involved 276 patients and showed a nearly two-fold increase in remission rates compared to treatment as usual.
A study published in International Journal of Geriatric Psychiatry found that antidepressants were associated with a lower risk of suicide among residents aged 75+, who had a significantly increased risk if taking sleep medication or having a history of self-harm. The research highlights the need for early recognition and quality care ...
A study led by UCLA Health scientists finds that highly creative people's brains exhibit an atypical approach to connectivity, enabling them to bypass traditional hubs and form distant connections. This 'road less traveled' pattern is more efficient for creative thinking but may not be optimal in all situations.
A new study finds that maternal feedback, not biological predisposition, influences reward-related brain activity in children of mothers with clinical depression. The research suggests that interventions coaching parents to encourage positive emotions may have a powerful impact on child development.
A systematic review of psilocybin interactions with psychiatric medications reveals a lack of scientific research, leaving clinicians and patients uncertain about treatment combinations. The review highlights the need for further studies on clinical outcomes of combining pharmaceutical medications with psilocybin.
A new study found that excessive daytime napping among seniors is associated with an increased risk of developing dementia and Alzheimer's disease. After a diagnosis of mild cognitive impairment or Alzheimer's, daytime napping duration triples, suggesting that the brain's wake-promoting neurons may be affected by dementia pathology.
Researchers found that people with severe alcohol use disorder reported missing 32 days of work each year, while those without the condition missed around 13 days. The study suggests that addressing alcohol use disorder in the workplace could lead to economic incentives and improved employee health.
A study of 181 long COVID patients found that seven in ten experience concentration and memory problems, with many performing worse than their peers on cognitive tests. Cognitive symptoms were more pronounced in people whose overall ongoing symptoms were more severe.
Brainwide association studies need thousands of individuals to yield higher reproducibility, as smaller samples often uncover strong but spurious associations. Larger sample sizes lead to more likely reproductions of correlations, with effect sizes decreasing as the number of participants increases.
Mayo Clinic researchers used AI to predict antidepressant outcomes in children and adolescents with major depressive disorder. They identified six depressive symptoms and assessed them using the Children's Depression Rating Scale-Revised to predict treatment outcomes.
Researchers from UCLA Health and Harvard Medical School propose a new approach to studying and applying psychedelic compounds to foster intentional changes in habits and behaviors, potentially leading to improved health and resilience.