Articles tagged with Psychiatry
A recent study published in Translational Psychiatry found that pharmacogenetic testing significantly improved symptoms in patients with treatment-resistant depression. The study involved 276 patients and showed a nearly two-fold increase in remission rates compared to treatment as usual.
Researchers found that maternal post-traumatic stress disorder (PTSD) severity in early childhood predicts child somatisation at school age. The study highlights the importance of considering family trauma history in pediatric consultations to improve patient care.
A study led by UCLA Health scientists finds that highly creative people's brains exhibit an atypical approach to connectivity, enabling them to bypass traditional hubs and form distant connections. This 'road less traveled' pattern is more efficient for creative thinking but may not be optimal in all situations.
A study published in International Journal of Geriatric Psychiatry found that antidepressants were associated with a lower risk of suicide among residents aged 75+, who had a significantly increased risk if taking sleep medication or having a history of self-harm. The research highlights the need for early recognition and quality care ...
A new study finds that maternal feedback, not biological predisposition, influences reward-related brain activity in children of mothers with clinical depression. The research suggests that interventions coaching parents to encourage positive emotions may have a powerful impact on child development.
A systematic review of psilocybin interactions with psychiatric medications reveals a lack of scientific research, leaving clinicians and patients uncertain about treatment combinations. The review highlights the need for further studies on clinical outcomes of combining pharmaceutical medications with psilocybin.
Researchers found that people with severe alcohol use disorder reported missing 32 days of work each year, while those without the condition missed around 13 days. The study suggests that addressing alcohol use disorder in the workplace could lead to economic incentives and improved employee health.
A study of 181 long COVID patients found that seven in ten experience concentration and memory problems, with many performing worse than their peers on cognitive tests. Cognitive symptoms were more pronounced in people whose overall ongoing symptoms were more severe.
A new study found that excessive daytime napping among seniors is associated with an increased risk of developing dementia and Alzheimer's disease. After a diagnosis of mild cognitive impairment or Alzheimer's, daytime napping duration triples, suggesting that the brain's wake-promoting neurons may be affected by dementia pathology.
Mayo Clinic researchers used AI to predict antidepressant outcomes in children and adolescents with major depressive disorder. They identified six depressive symptoms and assessed them using the Children's Depression Rating Scale-Revised to predict treatment outcomes.
Researchers from UCLA Health and Harvard Medical School propose a new approach to studying and applying psychedelic compounds to foster intentional changes in habits and behaviors, potentially leading to improved health and resilience.
Brainwide association studies need thousands of individuals to yield higher reproducibility, as smaller samples often uncover strong but spurious associations. Larger sample sizes lead to more likely reproductions of correlations, with effect sizes decreasing as the number of participants increases.
A USC-led study reveals that children with binge eating disorder show abnormalities in gray matter density compared to unaffected peers, indicating a possible link between the disorder and brain development. The findings suggest that treatment may need to address underlying brain abnormalities.
A recent study found that individuals with a history of neurological or psychiatric conditions are at increased risk of developing a second condition. Women and men differ in their risk, with women being more likely to develop dementia after experiencing an earlier stroke.
A new study led by UC San Francisco reveals that 87% of seniors with dementia would stop at least one medication if their doctor said it was possible. Polypharmacy contributes to challenges with adherence and adverse interactions, but most patients are willing to reduce their medications.
A study of nearly 158,000 US residents found that immigrants had increased financial worries in areas like retirement and medical costs, despite lower overall rates of psychological distress. However, serious psychological distress was associated with higher levels of financial worry in non-US-born individuals.
A recent study published in JAMA Psychiatry has found that individuals without jobs or stable housing experience worse depression symptoms when treated with therapy or antidepressants. The researchers analyzed data from nine studies involving over 4,800 participants and discovered that unemployed patients had 28% poorer outcomes compar...
A recent systematic review found that COVID-19 led to a 28% reduction in mental health service use among children and young people. The largest decrease was recorded in emergency department visits for mental health issues, with a 40% reduction on average.
The March issues of American Psychiatric Association journals focus on the genomics of psychopathology, exploring its relationship with various mental illnesses. Research highlights unique genetic patterns among individuals who die by suicide using violent means.
Researchers found significant increases in drug overdose mortality rates among racial and ethnic minority groups before the pandemic, which worsened during COVID-19. These disparities highlight the urgent need for targeted interventions to address opioid abuse and promote equitable access to healthcare services.
A new study found that women with bulimia nervosa exhibited reduced activation of the medial and lateral prefrontal cortices during attempts to control eating behavior. This deficiency in inhibitory control-related activation may contribute to more severe binge eating episodes.
Researchers from Tel Aviv University found that hyperbaric oxygen therapy (HBOT) relieves PTSD symptoms in treatment-resistant veterans, improving brain function and microstructure. The breakthrough study provides new hope for PTSD sufferers, offering an objective diagnostic tool and potential long-term improvements.
LaTrice Montgomery, a University of Cincinnati researcher, emphasizes the need for more specific data on cannabis use among different racial and ethnic groups. Her research focuses on cannabis addiction, also known as cannabis use disorder (CUD), which is listed in industry standard handbooks alongside other stimulants.
A new study of over 1.1 million new mothers worldwide found that first-time mothers, women under 25, and mothers of twins are at higher risk for postpartum depression. Women aged 40 and older having twins are particularly vulnerable to the condition.
A new study identifies common genetic factors in depression and Alzheimer's disease, suggesting a potential causal role of depression on dementia. The research found that depression played a significant role in AD development, with those experiencing worse depression experiencing faster memory decline.
Researchers found a significant association between mental disorders and dementia in a 30-year New Zealand study involving 1.7 million citizens. The study suggests that individuals with mental health conditions may be at higher risk of developing dementia, highlighting the importance of mental health care in preventing cognitive decline.
A study tracking 425 patients post-COVID-19 found high prevalence of cognitive deficits, psychiatric impairments, and significant memory decline. Researchers observed no correlation between the severity of the disease or socio-economic factors with psychiatric alterations, suggesting a possible link to delayed inflammatory processes.
A new study by University of Chicago researchers found no evidence that LSD microdosing improves mood and cognitive function. However, the study did confirm that taking small doses of LSD is safe, with participants building a tolerance to the drug over time.
A study by the Brazilian High-Risk Cohort Study for Childhood Psychiatric Disorders found an association between child poverty and externalizing disorders in adolescence and early adulthood. Child poverty was particularly harmful to women, increasing their risk of developing mental health problems and affecting educational attainment.
A recent study found that behavioral treatments can reduce ADHD symptoms and improve behavior in children, but not all children respond equally well. Priority should be given to those with more severe ADHD, conduct disorder symptoms, or from single-parent families, as they are at risk of deterioration without treatment.
Researchers found lower functional connectivity between brain areas involved in social and emotional processing in individuals at risk of developing alcohol use disorder. This impairment may affect their ability to interpret facial expressions and respond to their environment, increasing the likelihood of disordered drinking.
Markita del Carpio Landry, a young immigrant scientist, receives the Vilcek Prize for Creative Promise for her groundbreaking research on neurochemical communication and gene-editing technologies. Her work aims to address medicine's most compelling problems, including aberrations in neurotransmitter signaling.
A new study finds that adolescents with frequent suicidal thoughts are at risk for a range of psychological and social issues, including depression, anxiety, attention disorders, and more. Pediatricians can use screening tools to identify teens who need help, regardless of whether they will attempt suicide.
The February issues of The American Journal of Psychiatry and Psychiatric Services highlight new research on the opioid crisis, with a focus on improving treatment outcomes. Additionally, the latest issue of Focus features articles on novel neurotherapeutics and practice guidelines for peer specialists and supervisors.
A recent study published in Frontiers in Psychology found that women score higher on compassion-related items and self-reflection, whereas men score higher on cognitive-related items and emotional regulation. Both genders demonstrated an association with increased mental well-being and resilience.
Women with GAD exhibit abnormal interoception, perceiving intense heartbeats and lower neural activity in the ventromedial prefrontal cortex. The study suggests a causal link between cardiovascular sensitivity and frontal cortex insensitivity, contributing to anxiety symptoms.
The opioid crisis in the US has reached epidemic levels, with over 100,000 drug overdose deaths reported for the first time. The US Centers for Disease Control and Prevention attributes the rise to abuse of synthetic opioid fentanyl and the COVID-19 pandemic.
A recent study found an increase in intentional drug overdose deaths among young people aged 15-24, older adults aged 75-84, and non-Hispanic Black women. Despite a downward trend in overall deaths, these subgroups saw a rise in intentional overdose death rates, with women ages 45 to 64 having the highest rates.
Researchers at Children's Hospital of Philadelphia used deep learning to analyze whole genome sequencing data from African American patients with mental disorders. The model demonstrated over 70% accuracy in distinguishing between disorders and identifying multiple disorders.
A new study found that daily physical activity increases executive function performance in people aged 50-74, while decreased activity leads to lower cognitive performance. The correlation held even after adjusting for various co-morbidities.
A new study found that patients with chronic non-communicable diseases are more than twice as likely to die from any cause if they also have a psychiatric comorbidity. Comorbid psychiatric disorders were associated with higher all-cause mortality rates, ranging from 5.5-21.1%.
A virtual reality 'Shopping Task' has been developed to measure cognition and assess age-related decline. The study found that the immersive environment engaged key brain structures, including the hippocampus and entorhinal cortex.
A two-year randomized trial found that cannabis use significantly impaired driving ability, particularly in the first few hours after smoking. Despite varying levels of THC content and user history, participants displayed diminished skills on simulated driving tests.
A randomized controlled trial of combinatorial pharmacogenetics testing found no significant improvement in depressive symptoms among adolescents with depression. However, the study suggests that testing results may influence physician decision-making and could be useful in specific cases where individual gene-drug pairs impact clinica...
A study found that preventing mental health problems among schoolchildren, particularly externalizing disorders, could have prevented grade repetition and dropout. The study involved 2,511 families with children aged 6-14 and showed that girls with externalizing disorders were more likely to be held back a grade.
A University of Ottawa study found that trying to suppress emotions with a poker face or smile has little impact on mood and memory, contradicting past research. Instead, participants used alternative strategies like changing their perspective to cope with distressing moments.
Researchers at Massachusetts General Hospital have developed a portable brain imaging procedure using functional near-infrared spectroscopy (fNIRS) to detect acute impairment from THC intoxication. The technique shows promise in distinguishing between impairment and mild intoxication, with accuracy confirmed by machine learning models.
A new study led by Mount Sinai researchers found that microglia may play a critical role in some cases of brain disease, and provides a comprehensive guide for future studies. The study identified two new genes linked to brain disorders, including Alzheimer's and Parkinson's diseases.
Researchers have discovered a new biomarker, microstate D, associated with increased sleep disturbance and inattention symptoms in adults with ADHD. The study, published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, provides evidence for a more precise diagnosis of the disorder.
Researchers found that psilocybin doses of 10mg or 25mg administered simultaneously to up to six participants had no adverse effects. The study also showed promise for treating treatment-resistant depression and PTSD.
A new study reveals distinct DNA methylation profiles of human microglia cells across different age groups, disease states, and brain regions. The researchers found that interindividual differences in methylation variability had a larger impact than regional or diagnostic differences.
A study found that schools account for only 2.4% of variation in social-emotional-behavioral difficulties, depressive symptoms, and well-being among 11-14 year olds. School climate was associated with mental health, despite its small impact.
A new study found that white matter structural tracts are relatively stable throughout typical development, but show increased instability in children with psychosis spectrum symptoms. The integrity of these tracts was lower in children with psychosis and associated with cognitive function.
Research identifies maladaptive nature of drug-seeking habits as key factor in perpetuating addiction and relapse. Drug-paired cues can activate flexible goal-directed behaviors, driven by negative emotional urgency.
Research shows autistic adults on Medicaid have higher odds of co-occurring physical and mental health conditions, including diabetes, obesity, and epilepsy, compared to the general population. Racial and ethnic disparities are also evident, with Black, Hispanic, and Asian adults facing higher odds of certain conditions.
Middle-aged women with higher self-compassion had thinner carotid artery walls and less plaque buildup, linked to lower cardiovascular disease risk. The findings persisted even when controlling for behaviors and psychological factors.
A large observational study found that children conceived through assisted reproductive techniques (ART) have generally good mental health throughout adolescence and young adulthood. However, those born after ART had a slightly elevated risk of obsessive-compulsive disorder, which was explained by parental background factors.
A study published in PNAS found that individuals with severe schizophrenia have a higher number of rare mutations than those with typical forms of the illness. This discovery could lead to more precise treatments for this chronic disease, which affects over 3 million Americans.
A new study by Centre for Addiction and Mental Health reveals an association between trans individuals' need for acute mental health care and experiences of marginalization. Transgender individuals who access acute mental health care are twice as likely to be diagnosed with personality disorders than the general population.
A study in young psychiatric outpatients with episodic or chronic depression found differences in one-carbon and energy metabolism, which could aid in diagnosis and targeted treatments. The preliminary results suggest potential mechanisms behind chronicity, highlighting the need for larger cohorts to confirm findings.