Research from the field of mental-health medicine. Covers diagnostic agreement, youth psychiatric emergencies, schizophrenia genetics, and clinical leadership.
The Julich Brain Atlas provides detailed maps of brain cells and receptors, enabling better understanding of brain connectivity and function. The atlas allows for correlation between brain network activity and underlying anatomy, aiding in the diagnosis of psychiatric disorders.
Adolescents in war-torn regions experienced high war trauma and daily stress, with 60% witnessing armed attacks. The study found elevated rates of PTSD, anxiety, and depression compared to those living outside the conflict zone.
Researchers at USC found significant differences in gray matter density between boys and girls with binge eating disorder, suggesting unique brain structures and potentially different treatments. The study underscores the need to include males in future research on eating disorders.
Researchers conducted the largest clinical trial to date of psilocybin, finding a statistically significant rapid reduction in symptoms of depression. The study suggests that COMP360 psilocybin with psychological support could be an effective treatment strategy for people with treatment-resistant depression.
A recent study analyzing over 93,000 cases reveals a direct link between childhood trauma and the risk of developing a mental disorder in adulthood. The study highlights the importance of treating psychological trauma in patients and investing in prevention programs to reduce the risk of suffering a mental disorder.
A new study by UCL researchers found that problem drinking is associated with a higher risk of suicide and self-harm, particularly among those with 'probable dependence'. The study also identified signs of alcohol negatively impacting people's lives as risk factors.
The American Journal of Psychiatry focuses on the genetic underpinnings of psychiatric illnesses, while Psychiatric Services reports on community-based treatment programs for people with serious mental illness. The latest Focus journal issue explores borderline and other personality disorders.
A study in Brazil found that reducing childhood poverty could prevent up to 22.5% of future criminal convictions. The researchers analyzed 22 risk factors and interviewed over 1,900 children twice, finding that poverty was the only modifiable factor significantly associated with crime.
A new study published in NEJM Evidence found that crossword puzzle training significantly improved cognitive function and daily activities, reducing brain shrinkage in individuals with mild cognitive impairment. The findings suggest that engaging with familiar activities like crossword puzzles may be more effective than computerized co...
A new study found that psychological factors such as coping abilities play a significant role in individuals' risk or resilience to mental health disruptions during the COVID-19 pandemic. Brain connectivity within specific brain networks also predicted individual vulnerability to anxiety and depression symptoms.
Researchers at Rutgers University found that patients who participate in multiple outpatient visits early in treatment are more likely to continue care. Nearly half of these patients remained in treatment for six months or more, compared to just 2.9% of those with less frequent visits.
Researchers discovered two distinct types of regret linked to separate parts of the brain, influencing stress response and mood disorders. Stress-susceptible mice were hypersensitive to one type, while healthy mice were sensitive to another.
A recent study identifies a specific gene, GNL3, that regulates neural proliferation in response to lithium, which is used to treat bipolar disorder. This gene plays an important role in brain function and has been implicated in risk for bipolar disorder, schizophrenia, and inter-individual variations in intelligence.
A new randomized controlled trial evaluates the effectiveness of Parent-Child Care (PC-CARE), a seven-session intervention program, for children with challenging behaviors and their parents or caregivers. The study found that PC-CARE improves communication and reduces challenging behaviors in just seven weeks, with an 81% retention rate.
Research reveals that pregnant smokers decrease their daily cigarette count by an average of one cigarette per day before realizing they are pregnant. This trend continues in the month following pregnancy recognition, with a decline from nine to five cigarettes per day on average.
Research found that harsh parenting can lead to increased DNA methylation, predisposing children to depression. The study compared 21 adolescents with good parenting to 23 with harsh parenting and found significant differences in DNA methylation levels.
Researchers at UCalgary have shown that the antibiotic D-Cycloserine (DCS) increases the effectiveness of transcranial magnetic stimulation (TMS) for people with major depressive disorder. The combination treatment showed significant benefits, including improved depressive symptoms and anxiety levels.
The COVID-19 pandemic saw a significant decrease in hospital admissions for first-time clinical depression and recurrent depression, while outpatient treatment remained stable. This shift implies that many patients did not receive appropriate care for their condition, potentially leading to long-term quality of life loss.
Researchers found a healthy diet and avoiding stressful news helped prevent anxiety and depression during the pandemic. Engaging in physical exercise, staying outdoors, and drinking water also showed protective effects on mental health.
A new study suggests that phone calls and video chats can help patients access care, especially for those with barriers to traditional in-person visits. The study found that veterans who received virtual visits were more likely to stay on buprenorphine treatment, but there were disparities by race, housing status, and age.
A Rutgers-led study of over 2,700 pairs of twins found that adolescent alcohol misuse is associated with poorer life satisfaction, physical symptoms, and self-rated health in midlife. The study's findings suggest that teenage drinking may have long-lasting indirect effects on physical health and well-being.
A systematic review and meta-analysis found that psychotic disorders like schizophrenia are associated with a higher risk of developing dementia. People with psychotic disorders are 2.5 times more likely to develop dementia than those without a psychotic disorder, according to the review.
A new study found that fewer Asian, Black, and Hispanic patients qualify for anti-amyloid monoclonal antibody treatments, which may slow Alzheimer's progression. The treatment's effectiveness depends on the presence of amyloid plaques, with lower incidence in minorities.
Researchers used multi-omics technologies to analyze samples from 350 patients with major depressive disorder, finding distinct blood-based signatures between those with and without a history of attempted suicide. Variations in genes CLOCK and ARNTL were associated with lower antidepressant response rates.
A nationally representative study of 594,000 persons in England found an increased risk of suicide associated with dementia diagnosis before age 65. The study identified younger patients diagnosed within the 3-month post-diagnostic period as high-risk groups for suicidal thoughts and behaviors.
A clinical trial found that using positive words and images during the window of heightened brain plasticity after a single ketamine treatment can help maintain depression relief for at least one month. Researchers developed an automated intervention to pair ketamine with computer-based training, showing promising initial findings.
Researchers at Linköping University discovered a biological mechanism that increases the strength of fear memories stored in the brain. This finding provides new knowledge on the mechanisms behind anxiety-related disorders and identifies shared mechanisms with alcohol dependence.
A pooled data analysis found that deep brain stimulation reduced OCD symptoms by 47% and improved substantial outcomes in two-thirds of participants. This treatment approach showed promising results in addressing severe OCD with substantial improvement in approximately half of the patients.
The study found that nearly 9% of Americans aged 12 or older experienced a past-year major depressive episode. Depression was particularly common among adolescents (16.9%) and young adults (17%), with increased prevalence among various demographic groups, yet low help-seeking rates remained consistently low.
Researchers surveyed FAU residents on perceptions, coping strategies, and mental health during the pandemic. Residents reported effective coping mechanisms like acceptance, self-distraction, and emotional support, but found depression and anxiety levels in normal ranges.
Researchers at the University of Rochester Medical Center found that children who experience a mild traumatic brain injury are more likely to develop emotional and behavioral problems. The study, which analyzed data from thousands of children, revealed a 15-percent increased risk of these problems in kids with a mild TBI.
A study by University of Pittsburgh researchers found that older adults with consistent daily routines are happier, less depressed, and have better cognitive function. Participants who rose early, stayed active throughout the day, and followed a regular routine performed better on cognitive tests than those with disrupted patterns.
A new rodent study found that low doses of alcohol can trigger epigenomic and transcriptomic changes in the brain, creating an epigenetic pathway for addiction. The research suggests that even small quantities of alcohol can prime the brain for addiction, regardless of sex or quantity.
A UCD-led study found that 50% of people who developed schizophrenia and bipolar disorder had attended CAMHS in childhood, suggesting earlier intervention is key. The study highlights the possibility of intervening far earlier than present to prevent these illnesses.
A new study by a global team of researchers has revealed subtle alterations in the size of the brain's prefrontal region in young people with mood disorders and suicidal thoughts and behaviors. The study suggests that these associations may be absent or more difficult to identify in more diverse samples.
Researchers studied over 500,000 children born between 1987 and 2010, finding no causal link between maternal infection and autism. However, they did find a weaker link for intellectual disability, suggesting other factors may be at play.
A recent study found that nearly 1 in 3 mental health prescriber visits to Medicare patients were provided by PMHNPs, a significant rise from 2011-2019. The growth of PMHNPs helped offset the decline of psychiatrists treating Medicare patients, resulting in a 12% decrease in mental health specialist visits instead of a 30% drop.
The September issues of American Psychiatric Association journals focus on combining molecular and neuroimaging measures to understand psychopathology and inform new treatment development. Featured research includes studies on early childhood psychotic experiences and schizophrenia imaging signatures.
A study by researchers at the University of Cambridge found no difference in motivation or enjoyment between adult and adolescent cannabis users and non-users. Cannabis use was not linked to apathy, anhedonia, or brain response to rewards. The findings contradict common stereotypes portrayed in media.
A study using child-sized humanoid robots found that they can assess mental wellbeing in children more effectively than parent-reported or self-reported testing. The robots were able to encourage children to share their thoughts and feelings, leading to more accurate assessments of their mental health.
A study of 641 participants found that midlife and older Hispanic/Latinx adults were more likely to experience prolonged loneliness, with 16% persistently lonely. The researchers suggest that culturally important familism was disrupted by social distancing, and reduced access to transportation and community activities may contribute to...
Young people with 22q11.2 Deletion Syndrome show distinct brain activity patterns during sleep, which may influence psychiatric symptoms. These differences are associated with altered connections within and between brain areas.
Researchers found that mothers' higher depressive symptoms did not predict increases in children's behavior problems, including those with autism. The study suggests that maternal depression may have a complex impact on caregiving families.
A study of 137 children with early-onset psychosis found that over 70% had copy number variants, a common cause of neurodevelopmental disorders. The research suggests that chromosomal microarray testing can bring closure to families and improve treatment outcomes.
A Rutgers University study reveals that nearly 40% of medical marijuana users also use nicotine products, sharply higher than the general population. The study found that therapeutic cannabis users who also used electronic cigarettes or didn't use nicotine at all were more likely to vape cannabis.
A national survey of US psychiatrists found discrepancies between their perceptions of certain psychoactive drugs' safety and therapeutic value and how they are categorized under the Controlled Substances Act. Psychiatrists rated psilocybin as having low misuse potential and high therapeutic potential, but it is a Schedule I drug with ...
A study published in Molecular Psychiatry reveals that deep brain stimulation (DBS) to the superolateral branch of the medial forebrain bundle can alter metabolic brain changes over 12 months, making it a strong potential therapy for treatment-resistant depression. The results showed that 8 out of 10 patients experienced significant sy...
A study by UCSF found that routine depression screening in primary care increased rates from 40.5% to 88.8%, capturing previously undertreated groups. Screening disparities virtually disappeared for older patients, Black/African Americans, and non-English speakers.
A study found a strong link between post-COVID loss of smell or taste and memory problems in patients. Those with the most severe sensory disorders performed worse in cognitive tests, especially memorization.
A randomized controlled trial found that virtual museum visits significantly improved the health of seniors stuck at home, reducing social isolation and improving well-being, quality of life, and frailty. The study recruited 106 participants aged 65 and older who attended guided tours online once a week for three months.
A new study found that COVID-19 lockdowns significantly increased suicidal ideation and suicide attempts among patients with serious mental illness in Serbia. The study also highlighted the need for protections to mitigate mental health consequences during future lockdowns.
Researchers found that 41% of schizophrenia patients met the criteria for frontotemporal dementia, a condition characterized by personality changes and behavioral alterations. The study suggests that targeting specific brain regions and neural structures may lead to improved treatment outcomes for this subgroup.
A large-scale study of nearly 12,000 children aged 9-10 found that disordered eating behaviors are more common than previously thought, with a prevalence of up to 5% in some cases. Children with higher BMIs and those further along in puberty face an elevated risk, highlighting the need for targeted prevention efforts.
A new study shows that telehealth, particularly audio-only visits, helped keep VA patients on medication for opioid use disorder during the pandemic. Phone visits also played a key role in reducing dropouts from care.
Researchers at the University of Wisconsin-Madison's Center for Healthy Minds found that mindfulness training alters specific pathways in the brain related to pain regulation. Participants who completed an eight-week Mindfulness Based Stress Reduction course showed a reduction in pain-related brain activity, suggesting a potential new ...
Low to moderate stress levels may enhance cognitive functioning and reduce the risk of developing mental health disorders. Participants who experienced low to moderate stress demonstrated better coping mechanisms and improved neurocognitive abilities.
A large-scale survey of 62,000 participants found a significant association between everyday discrimination and moderate to severe depressive symptoms during the pandemic. Participants from Hispanic or Latino and non-Hispanic Asian backgrounds who experienced racism were at higher risk for these conditions.
Research found that everyday discrimination during COVID-19 led to increased odds of moderate to severe depression and suicidal ideation, particularly among Hispanic/Latino and Asian/Pacific Islander participants. The study highlights the need for clinicians and society to address the toll of discrimination on mental health.
A study by University of Warwick found that worsened financial situation and sleep difficulties are key indicators of individuals at higher risk of developing mental health issues. The research, based on a survey of 895 university students, revealed a reduction in mental health symptoms over time as financial difficulties and sleep irr...
A study found that Black adolescents experienced high rates of online racial discrimination, which predicted worse mental health outcomes. The researchers suggest that recognizing online spaces as impediments to mental growth and well-being is crucial.