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HKUMed and University of Melbourne-led global research team confirms the long-term safety of methylphenidate in children and adolescents with ADHD

A global research team found that long-term methylphenidate treatment does not increase the risk of growth impairments or psychiatric events, but may lead to modest increases in blood pressure. The study suggests potential disparities in ADHD medication access by country-income levels.

SourceThe University of Hong Kong·JournalThe Lancet Psychiatry·TypeExperimental study·DateMar 28, 2023

Can cannabis use disorder be accurately diagnosed?

Researchers at Rutgers University propose a new approach to accurately diagnosing cannabis use disorder, particularly for individuals who use cannabis for therapeutic purposes. The current diagnostic manual may misdiagnose these individuals due to the rapid increase in state-level legalization of medical marijuana.

SourceRutgers University·JournalJAMA Psychiatry·TypeData/statistical analysis·DateMar 27, 2023

How the brain's 'internal compass' works

A new study has uncovered the brain's internal compass, which helps it navigate changing environments. The research found that the brain uses a mechanism called 'network gain' to reorient itself after being disoriented, allowing for rapid recovery of its sense of direction.

SourceMcGill University·JournalNature·TypeExperimental study·DateMar 22, 2023

Progress in unlocking the brain's "code" for depression

Researchers collected electrophysiological recordings from prefrontal cortical regions in three human subjects with severe treatment-resistant depression. They found lower depression severity correlated with decreased low-frequency neural activity and increased high-frequency activity.

SourceElsevier·JournalBiological Psychiatry·TypeExperimental study·DateMar 16, 2023

Characterizing abnormal neural networks in dogs with anxiety

Researchers found that dogs with anxiety have altered brain connectivity, particularly between the amygdala and hippocampus. The study used fMRI to characterize abnormal neural networks in anxious dogs, providing insight into anxiety disorders in both animals and humans.

SourcePLOS·JournalPLOS ONE·TypeObservational study·DateMar 15, 2023

Dementia the top COVID-19 risk factor for seniors in care

A University of Gothenburg study reveals that dementia is the dominant risk factor for COVID-19 infection and mortality among residents of Swedish nursing homes. Early-onset dementia was found to be the strongest association with increased mortality rates, particularly in the 65–75 age group.

SourceUniversity of Gothenburg·JournalAmerican Journal of Geriatric Psychiatry·TypeData/statistical analysis·DateMar 8, 2023

March issues of American Psychiatric Association journals cover advances in depression treatment, suicide risk screening, and mental health help seeking among Indigenous populations

The March issues of The American Journal of Psychiatry and Psychiatric Services focus on major depression treatment advances and suicide risk screening for Indigenous populations. Journalists can access the publications by emailing press@psych.org.

SourceAmerican Psychiatric Association·JournalAmerican Journal of Psychiatry·DateMar 2, 2023

Palliative care doesn’t improve psychological distress

A Rutgers study found no statistically significant improvements in patient or caregiver anxiety, depression, or psychological distress in palliative care interventions. The researchers identified conceptual and methodological problems in the literature, including excluding patients with existing mental health conditions from studies.

SourceRutgers University·JournalJournal of Pain and Symptom Management·TypeMeta-analysis·DateFeb 24, 2023

Brain structural differences observed in children with conduct disorder with and without childhood maltreatment

A new study found that children with conduct disorder who experienced childhood maltreatment have more extensive brain structural changes compared to those without maltreatment. The study highlights the unique contribution of childhood maltreatment to these changes and provides neurobiological insights into the heterogeneity of CD.

SourceElsevier·JournalBiological Psychiatry·TypeObservational study·DateFeb 7, 2023

February issues of American Psychiatric Association journals cover risk factors for mental illness, substance use in psychiatric care, emergency psychiatry and more

The February issues of the American Psychiatric Association's journals address risk factors for mental illness and substance use in psychiatric care. The research highlights the importance of understanding these factors to improve treatment outcomes and reduce disparities in mental health care.

SourceAmerican Psychiatric Association·JournalAmerican Journal of Psychiatry·DateFeb 2, 2023

Β-blocker use associated with lower rates of violence

A study of 1.4 million individuals found β-blocker use associated with a 13% lower risk of violent crime and an 8% lower risk of hospitalization due to psychiatric disorders. The findings suggest that β-blockers may be considered as a way to manage aggression and hostility in individuals with psychiatric conditions.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateJan 31, 2023

Support from others in stressful times can ease impact of genetic depression risk, study suggests

A recent study found that social support has a significant impact on depression risk, particularly in individuals with high genetic risk scores. The research used data from two groups: first-year doctors and recently widowed older adults, showing that those who gained social support during stressful times had lower depressive symptoms.

SourceMichigan Medicine - University of Michigan·JournalAmerican Journal of Psychiatry·TypeData/statistical analysis·DateJan 13, 2023

How differences in diagnoses of mental disorders might affect clinical research outcomes for antipsychotics

A study from Japan found that variations in psychiatric diagnoses across different cultures can affect the efficacy of antipsychotics in clinical trials. Researchers analyzed data from 28 double-blind randomized trials and found that psychotic features were associated with varying therapeutic responses to antipsychotic medications.

SourceFujita Health University·JournalPsychiatry and Clinical Neurosciences·TypeMeta-analysis·DateJan 10, 2023

Do the negative ways that others treat us contribute to later self-harm?

A new longitudinal study examines neural-based correlates and risk factors for nonsuicidal self-injury (NSSI) among adolescents. The study found that greater amygdala reactivity during anticipation of social punishment predicted NSSI engagement one year later, particularly in those with lower peer-nominated social preference.

SourceElsevier·JournalBiological Psychiatry·TypeObservational study·DateJan 5, 2023

Racism takes its toll on brain and body

A new study finds that discrimination influences the central and enteric nervous systems, altering the bidirectional signaling between the brain and gut microbiome. This leads to changes in systemic inflammation, emotional arousal, and psychological symptoms across different racial and ethnic groups.

SourceElsevier·JournalBiological Psychiatry·TypeData/statistical analysis·DateDec 13, 2022

Internet treatment for anger works

A new study from Karolinska Institutet shows that internet-based therapy can help people with anger and aggression, with a combination of mindful emotion awareness and cognitive reappraisal being the most effective strategy. Four-week treatments resulted in decreased self-reported anger and aggressiveness.

SourceKarolinska Institutet·JournalJournal of Consulting and Clinical Psychology·TypeRandomized controlled/clinical trial·DateDec 12, 2022

People with mental disorders lose years of their working life

A new study from Aarhus University found that people diagnosed with mental disorders work 10.5 years less than the general population. The researchers analyzed data from over 5 million individuals in Denmark and found that all types of mental disorders are associated with a substantial loss of working life.

SourceAarhus University·JournalThe Lancet·TypeData/statistical analysis·DateDec 6, 2022

December issues of American Psychiatric Association journals cover technology and mental health, new approaches with psychopharmacology, and improving correctional care

The American Psychiatric Association's December journal issues explore new therapeutic approaches involving psychopharmacology, digital technology, and fMRI neurofeedback. The APA also highlights its vision to ensure access to quality psychiatric diagnosis and treatment.

SourceAmerican Psychiatric Association·JournalAmerican Journal of Psychiatry·DateDec 2, 2022

Reduced use of child sexual abuse material after online CBT

Researchers at Karolinska Institutet found that internet-delivered anonymous cognitive behavioural therapy (CBT) significantly reduced the viewing of child sexual abuse material. The study, published in Internet Interventions, shows promise for a feasible and effective treatment approach.

SourceKarolinska Institutet·JournalInternet Interventions·TypeRandomized controlled/clinical trial·DateNov 30, 2022

ADHD medication for amphetamine addiction linked to reduced risk of hospitalization and death

A large registry-based study found lisdexamfetamine to be associated with the lowest risk of hospitalisation and death in people with amphetamine addiction. The medication showed a significant reduction in hospitalisation due to substance use disorder and any cause or death, while benzodiazepine and antidepressant use were linked to po...

SourceKarolinska Institutet·JournalJAMA Psychiatry·DateNov 16, 2022

Corporal punishment affects brain activity, anxiety, and depression

A new study explores how corporal punishment impacts neural systems, linking it to increased anxiety, depression, and altered brain activity. The research found that adolescents who experienced physical punishments showed a larger neural response to error and a blunted response to reward.

SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeExperimental study·DateNov 16, 2022