Articles tagged with Psychiatry
The ESCAPE-TRD study found that esketamine nasal spray outperforms quetiapine in treating treatment-resistant major depression, with patients showing higher remission rates and reduced depressive symptoms. The results suggest esketamine as a safe and effective treatment option for those with treatment-resistant depression.
New research reveals that children with childhood mental health issues are at higher risk of social isolation, low educational attainment, financial difficulties, and heavy substance use in late teens and early 20s. The study also found a strong link between internalising symptoms and poor physical health in young adulthood.
Researchers found that women experience a significant increase in anxiety and negative feelings during the 7-day pill-free period, similar to those experienced during menstruation. Long-term pill users may benefit from mood-stabilizing effects while taking their pill.
A study published by the University of Birmingham found that people living in Gaza with intermittent electricity supplies experienced higher levels of anxiety and depression, while those with reliable access had improved wellbeing. The researchers emphasized the urgent need for sustainable energy solutions to address this crisis.
A randomized controlled trial found that cognitive behavioral therapy (CBT) significantly reduces fibromyalgia pain by decreasing pain-catastrophizing, a negative response that amplifies pain. CBT participants showed reduced connectivity between brain regions associated with self-awareness and emotional processing.
A new evaluation tool, HiDE, offers practical guidance for diagnosing hikikomori, a form of extreme social isolation. The tool provides structured interview questions for clinicians to diagnose the condition, which is characterized by stress caused by months-long isolation at home.
A study by the University of Gothenburg reveals that obesity significantly worsens life expectancy and mortality risks in individuals with bipolar disorders. The findings show a rapid increase in BMI among those with bipolar disorders, leading to a higher risk of premature death and comorbidity.
The ECNP 2023 conference will feature discussions on a wide range of new work in clinical and applied neuroscience among over 5000 attendees from around the world. Accredited journalists are welcome to attend and register for online access.
A new study uses brain imaging to explore the neural underpinnings of uncertainty processing in OCD, finding that patients struggle with certainty and decision-making, particularly when outcomes are more certain. This understanding may offer new hope for developing therapies targeting uncertainty processing in OCD.
A Northwestern University study found that endogenous cannabinoid molecules released by the brain during stress can calm it down. These molecules activate the same receptors as THC and may provide a natural coping response to stress.
Research found that a healthy lifestyle involving moderate alcohol consumption, healthy diet, regular physical activity, and frequent social connection can reduce the risk of depression. The study identified seven healthy lifestyle factors linked to a lower risk of depression, with good sleep being the most protective.
Sahmyook University researchers discovered a correlation between methamphetamine-induced behavior and the expression of specific genes in mice models lacking Period 2 gene. They identified 19 genes that were activated only in response to repeated doses of methamphetamine.
A new survey by USC Street Medicine found that street medicine programs are helping to fill the gap in access to mental health and substance use treatments for unhoused individuals in California. The study suggests that these programs can serve as a strategy to expand access to behavioral health care for people who are unsheltered.
The latest issues of American Psychiatric Association journals focus on postpartum depression, structural racism, and suicidal behaviors. The September issue highlights new solutions to address these topics, including Power Redistribution and Upending White Supremacy in Community Mental Health.
Research highlights associations between adverse childhood experiences (ACEs) and workers' insomnia among Japanese adults. ACEs, including bullying and family dysfunction, are known to have detrimental health consequences.
Research found that selective serotonin reuptake inhibitor (SSRI) treatment for postnatal depression was associated with reduced child behavioral difficulties, ADHD symptoms, and maternal depression. The study also suggested long-term benefits of SSRI treatment on child outcomes up to five years after childbirth.
A study of over 4.4 million residents at 15,000 skilled nursing facilities found that telemedicine use was higher than pre-2020 levels and associated with improved access to psychiatry visits. Higher adoption rates were linked to better outcomes for patients in these facilities.
A randomized clinical trial found that exercise significantly reduced depressive symptoms and burnout in healthcare workers, while improving mental health. However, low adherence to exercise programming was noted towards the end of the study.
Researchers at Lund University discovered that psychedelic substances LSD and ketamine cause simultaneous synchronisation of neurons in several brain regions. This phenomenon is linked to the psychedelic experience and may hold clues for understanding psychoses and consciousness.
Researchers propose GABA-modulating treatments as potential therapeutic targets for depression's cognitive and affective symptoms. The study highlights the importance of GABA-A receptors in regulating balance and signals between neurons, and suggests compounds that promote or inhibit these receptors may alleviate depressive symptoms.
Researchers found that adults who experienced violence, financial stress, or separation from parents as children were more likely to experience physical and cognitive impairments. Adverse childhood experiences can have lifelong consequences, including difficulty walking, carrying out daily activities, and problems with memory.
A randomized controlled trial found that Nurse-Family Partnership improved child language and mental health at age 2, with no increase in child injuries or maternal pregnancies. The study involved 739 participants and their children for 2.5 years, providing new evidence on preventing early adverse childhood experiences.
Researchers found a clear pattern of suicidality related to the academic calendar, with peaks in April and October, but a decline during COVID-19 school closures. The study suggests interventions during peak months could help protect against seasonal increases in suicidality, especially for adolescent females.
A low-cost version of ketamine has shown strong results in treating treatment-resistant depression, with over 20% participants achieving total remission and a third experiencing symptom improvement. The study's findings bring definitive evidence to the field, which can be more affordable than existing treatments.
A new report suggests that AI-powered robot companions could alleviate the loneliness epidemic and its associated health risks. Companion robots have already shown promise in reducing stress and promoting physical and mental well-being in socially isolated older adults.
During the pandemic, acute care use for mental health conditions among youth increased notably, particularly among adolescent females. Prolonged boarding in emergency departments and waiting for inpatient psychiatric care are concerning trends that require interventions to address.
The USC PRECOG project aims to develop automated screening tools for clinicians using objective neural and physiological signal biomarkers. The team will advance interdisciplinary methods in neuroscience, linguistics, and machine learning to better understand mental health risk factors.
Researchers identified three neurobehavioral profiles that distinguish individuals with elevated mania vulnerability based on reward sensitivity and sleep-circadian characteristics. These profiles can help detect mania risk and provide targets for early interventions.
Researchers at the University of Pittsburgh School of Medicine found no evidence that prescription stimulant treatment in childhood increases the risk of substance use disorder (SUD) later in life. The study, published in JAMA Psychiatry, suggests that stimulants are an effective treatment for ADHD with few side effects.
A new study finds nearly two-thirds of Medicare Advantage psychiatrist networks contain less than 25% of all psychiatrists, leaving many seniors without access to mental health care. The research suggests that this limited coverage may lead to higher out-of-pocket costs, delays in care, and foregone treatment.
Researchers at Korea University Medicine identified a new neuroimaging-based biomarker for MDD, the local gyrification index (LGI), which shows decreased cortical folding in patients. LGI values reflect long-drawn developmental processes and are stable markers compared to previous biomarkers.
A study led by Lund University researchers found that brief admissions by self-referral can effectively reduce the need for acute visits, admissions, and longer treatment periods among adolescents with borderline personality disorder. The method empowers patients to determine when they need treatment, enhancing their autonomy and sense...
A new study from Aarhus University found that people with mental health issues are less likely to accept offers of colorectal cancer screening. The research showed that those with severe mental disorders had a 13.8 percentage point lower participation rate compared to those without mental illness.
Researchers used brain imaging to identify multiple subtypes of depression, finding distinct deviation patterns in functional connectivity among brain regions. This study provides leads for developing better treatments and personalized therapeutic interventions.
A study found that exposure to events against moral values and lack of confidence about raising safety concerns significantly contributed to staff distress. One-in-ten healthcare workers reported experiencing suicidal thoughts six months after completing a survey.
The use of psychedelics in mental health treatment is gaining traction, but concerns about patient safety and regulation need to be addressed. Psychedelic-assisted therapy shows promise in treating conditions like depression and PTSD, but more research is needed on dosages, settings, and guidelines.
A new pilot study published in JAMA Psychiatry demonstrates the potential role of probiotic supplementation in supporting mood and mental health in adults with Major Depressive Disorder. The study found significant improvements in depression and anxiety scores over an eight-week period, with notable benefits seen from week four onwards.
The Better Together trial partners with community organizations and sites to provide buprenorphine treatment, reducing distance for patients and offering peer support in familiar environments. Researchers aim to address barriers such as stigma, misunderstandings about addiction, and bias against certain treatments.
A new study found that LGB adults are more than twice as likely to experience suicidal thoughts or self-harming behaviors compared to straight peers. Depression, anxiety, and experiences of discrimination and bullying contribute to these increased risks.
The June issues of The American Journal of Psychiatry and Psychiatric Services focus on substance use disorders, opioids, and youth self-harm and suicide. The articles highlight the importance of addressing these issues to improve patient outcomes and reduce stigma.
A study found that nursing and clerical staff experienced higher levels of psychological distress due to fear of COVID-19. In contrast, physicians had higher resilience levels. The availability of in-hospital support and consultation on infection control also played a role in mitigating fear and stress.
A recent study published in JAMA Psychiatry found that fewer boys aged 15-19 commit suicide in Swedish regions with higher bipolar diagnoses. The study, which analyzed registry data from 2008 to 2021, showed an inverse association between population-adjusted bipolar diagnoses and confirmed suicides among males.
A clinical trial of 403 patients found that ketamine treatment was non-inferior to ECT for treating non-psychotic treatment-resistant depression. Ketamine showed fewer side effects than ECT, with improved depressive symptoms and quality of life.
New research highlights the benefits of family-based care for children exposed to early psychosocial deprivation, improving cognitive function, emotional well-being, and social development. The study found that high-quality foster care had a lasting impact on children's brain development and risk of psychopathology.
A team of researchers developed a deep-learning model called WearNet that uses Fitbit data to detect depression and anxiety. The study found that WearNet performed better than state-of-the-art machine learning models in detecting these conditions, producing individual-level predictions.
Researchers have identified a brain marker that may indicate future suicide risk, suggesting potential new treatments and prevention strategies. The study found differences in brain connections among veterans with a history of suicide attempts compared to those without, which could help identify individuals at risk.
A new pilot study led by University of Illinois Chicago researchers found that an AI voice-based virtual coach improved depression and anxiety symptoms, as well as problem-solving skills, in patients. The Lumen app delivered a form of psychotherapy, resulting in changes in brain activity and reduced psychological distress.
A nationwide register-based study found significant increases in psychiatric diagnoses among Finnish children and adolescents during the pandemic, with notable rises in eating disorders, depression, and anxiety. The research highlights concerns about gaps in services and accessibility during times of crisis.
Researchers at MIT's Picower Institute used a nematode worm to study serotonin's effects on behavior and brain activity. They identified three key receptors driving slowing behavior and found complex interactions between serotonin receptors modulating brain-wide activity.
Cocaine use disorder has been rising for over a decade, with no robust treatment available. Researchers are using cocaine contingency management to provide cash or value in exchange for drug-free urine samples, aiming to change an individual's temporal horizon and reduce consumption. The study aims to guide innovative interventions tha...
Hoarding disorder affects 2% of the population with clutter in homes and excessive acquisition of possessions. The new guidance provides best practice for diagnosing and supporting those affected.
The latest May issues of American Psychiatric Association journals focus on new treatments for conditions like trichotillomania, social anxiety disorder, and opioid use disorder. Additionally, a special issue of Focus journal explores suicide preventive interventions and knowledge.
Researchers discovered that sleep spindles can alleviate anxiety in people with post-traumatic stress disorder (PTSD), contradicting recent findings. The study found that spindle rate frequency was higher during a stressful visit than a control visit, suggesting non-invasive ways to harness the benefits of this sleep stage for symptom ...
A recent study reveals that many children with attention-deficit/hyperactivity disorder (ADHD) are not receiving adequate treatment. The findings highlight the need for improved communication and access to outpatient mental health care for children with ADHD.
Researchers have created a new manual to study human diseases, using evolutionary genomics to analyze genetic risk. The manual reveals the importance of highly constrained genes that unite mammals, providing insights into neurological disorders and psychiatric conditions.
Research suggests that problems with the brain's ability to 'prune' itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence. Adolescents experiencing mental health problems showed similar patterns of brain activity, which were largely apparent in the frontal lobes.
A recent study published in JAMA Psychiatry found that individuals with a family history of depression exhibit reduced cognitive abilities. The research highlights the potential impact of genetic and environmental factors on brain development and aging, as well as modifiable lifestyle factors.
Researchers from RCSI University of Medicine and Health Sciences identified 17 factors that can predict ADHD symptoms in childhood, including sex, cigarette smoke exposure, and mother's urinary tract infections. The study suggests that prenatal information may help identify children at risk of developing ADHD, particularly when combine...
A new study found that emotion-focused therapy increased activation and connectivity of the amygdala in patients with bipolar disorder, leading to improved emotion processing. In contrast, cognitive-behavioral therapy showed increased activation of brain regions related to social function but not altered amygdala activity.
Research found that individuals with schizophrenia spectrum disorder have erratic sleep patterns and rigid daily routines, predictive of worse symptoms. The study suggests varying daily routines and incorporating movement can improve brain health and reduce negative mental health symptoms.