Articles tagged with Psychiatry
Research reveals that brain inflammation is the primary cause of neuropsychiatric symptoms in Alzheimer's disease, including irritability, agitation, and anxiety. The study found a strong association between microglial activation and neuropsychiatric symptom severity, suggesting new pathways for therapy development.
Researchers from the Amsterdam University Medical Centre conducted a study on patients who choose to voluntarily stop eating and drinking (VSED) to hasten death. They identified three distinct groups: older patients seeking control over their lives, care-dependent patients with poor quality of life, and younger psychiatric patients. Th...
A study of 278,000 individuals in Sweden found that longer cumulative duration of ADHD medication use was associated with an increased risk of hypertension and arterial disease. Clinicians should regularly monitor cardiovascular signs and symptoms during long-term treatment.
Researchers developed a new diagnostic tool to identify and treat Hikikomori, a condition characterized by prolonged physical isolation or social withdrawal. The Hikikomori Diagnostic Evaluation (HiDE) assesses the severity of social withdrawal, providing a practical guide for clinicians.
A new study from UCLA Health researchers demonstrates that repetitive transcranial magnetic stimulation (rTMS) is effective in most patients with major depressive symptoms, starting to alleviate symptoms as quickly as one week. The treatment was found to be associated with a significant response rate of 54% of patients, with early impr...
Rahn Baily, MD, has made significant contributions to the field of psychiatry and healthcare reform through his research on health disparities, violence, and mental illness. He will receive the prestigious Solomon Carter Fuller Award for his outstanding achievements in addressing pressing societal needs.
Researchers propose a new hypothesis that ECT alleviates depression symptoms by increasing aperiodic activity in the brain. Aperiodic activity helps boost inhibitory activity, slowing down neuronal cycles and effectively controlling how neurons turn on and off. The studies also found similar effects in magnetic seizure therapy.
Research from Karolinska Institutet found that non-European individuals in Sweden have a higher prevalence of eating disorder symptoms, but limited access to specialist care. The study reveals a significant gap between those with disordered eating and those receiving specialized treatment.
The latest APA journal issues provide new insights into psychotic disorders, including altered neurodevelopment and early symptoms associated with schizophrenia risk. The issues also highlight racial disparities in diagnosis and predictors of first psychotic episodes. Psychiatric Services features research on barriers to addiction trea...
A new study in Nature Communications presents a large-scale chart of cognitive development in teens, revealing that executive function usually matures by 18 years old. The findings have significant implications for psychiatrists, neuroscientists, parents, educators, and the judicial system.
A large-scale study found that metformin can reduce weight gain and increase adherence to treatment in youth with bipolar disorder. The medication, typically used for Type 2 diabetes, was effective in preventing weight gain and showed promise as a potential solution to this common side effect of SGAs.
A study by Nagoya University found that children with a genetic predisposition to autism spectrum disorder (ASD) used screens for longer periods. Children with attention deficit hyperactivity disorder (ADHD) also increased their screen time as they grew older, suggesting a potential link between genetic risk and excessive screen use.
Researchers found that hierarchical cortical organization is impaired in people with schizophrenia, leading to disruptions in processing stimuli from the external world. This disruption affects secondary processing of sensorimotor-visual gradients, explaining behavioral and clinical symptoms of the disease.
A long-term study found that changes in core autism characteristics are related to the development of mental health challenges during elementary school years. Restrictive and repetitive behaviors may help reduce anxiety for autistic individuals.
A major study has found that taking benzodiazepines like Valium and Ativan intermittently instead of continuously can lead to significant reductions in side effects such as falls, hip fractures, hospitalizations, and even death. The research showed a 20% decrease in hip fractures, 33% fewer men's falls requiring hospitalization, and a ...
Researchers found that antidepressant escitalopram increases synaptic density in the brain over weeks, leading to greater brain plasticity. This explains why effects of antidepressants take time to kick-in, with significant differences in synapse density between treatment and placebo groups.
Researchers found that training expectant mothers can improve their ability to recognize happy baby expressions, leading to fewer signs of depression. This new approach aims to promote healthier emotional development for both mother and child.
Previous studies suggest that psychedelics can induce an altered state of consciousness leading to new thought patterns, which is promising in treating OCD. Research analyzing the experience of past users found dissipation of obsessive thoughts, reduced anxiety, and increased acceptance of OCD symptoms.
Researchers developed a wearable device to track bipolar disorder patients' skin electrical activity, detecting manic and depressed phases. The study aims to improve diagnosis and treatment with personalized, rapid interventions.
The ESCAPE-TRD study found that esketamine nasal spray outperforms quetiapine in treating treatment-resistant major depression, with patients showing higher remission rates and reduced depressive symptoms. The results suggest esketamine as a safe and effective treatment option for those with treatment-resistant depression.
New research reveals that children with childhood mental health issues are at higher risk of social isolation, low educational attainment, financial difficulties, and heavy substance use in late teens and early 20s. The study also found a strong link between internalising symptoms and poor physical health in young adulthood.
Researchers found that women experience a significant increase in anxiety and negative feelings during the 7-day pill-free period, similar to those experienced during menstruation. Long-term pill users may benefit from mood-stabilizing effects while taking their pill.
A study published by the University of Birmingham found that people living in Gaza with intermittent electricity supplies experienced higher levels of anxiety and depression, while those with reliable access had improved wellbeing. The researchers emphasized the urgent need for sustainable energy solutions to address this crisis.
A randomized controlled trial found that cognitive behavioral therapy (CBT) significantly reduces fibromyalgia pain by decreasing pain-catastrophizing, a negative response that amplifies pain. CBT participants showed reduced connectivity between brain regions associated with self-awareness and emotional processing.
A study by the University of Gothenburg reveals that obesity significantly worsens life expectancy and mortality risks in individuals with bipolar disorders. The findings show a rapid increase in BMI among those with bipolar disorders, leading to a higher risk of premature death and comorbidity.
A new evaluation tool, HiDE, offers practical guidance for diagnosing hikikomori, a form of extreme social isolation. The tool provides structured interview questions for clinicians to diagnose the condition, which is characterized by stress caused by months-long isolation at home.
The ECNP 2023 conference will feature discussions on a wide range of new work in clinical and applied neuroscience among over 5000 attendees from around the world. Accredited journalists are welcome to attend and register for online access.
A Northwestern University study found that endogenous cannabinoid molecules released by the brain during stress can calm it down. These molecules activate the same receptors as THC and may provide a natural coping response to stress.
A new study uses brain imaging to explore the neural underpinnings of uncertainty processing in OCD, finding that patients struggle with certainty and decision-making, particularly when outcomes are more certain. This understanding may offer new hope for developing therapies targeting uncertainty processing in OCD.
Research found that a healthy lifestyle involving moderate alcohol consumption, healthy diet, regular physical activity, and frequent social connection can reduce the risk of depression. The study identified seven healthy lifestyle factors linked to a lower risk of depression, with good sleep being the most protective.
Sahmyook University researchers discovered a correlation between methamphetamine-induced behavior and the expression of specific genes in mice models lacking Period 2 gene. They identified 19 genes that were activated only in response to repeated doses of methamphetamine.
A new survey by USC Street Medicine found that street medicine programs are helping to fill the gap in access to mental health and substance use treatments for unhoused individuals in California. The study suggests that these programs can serve as a strategy to expand access to behavioral health care for people who are unsheltered.
The latest issues of American Psychiatric Association journals focus on postpartum depression, structural racism, and suicidal behaviors. The September issue highlights new solutions to address these topics, including Power Redistribution and Upending White Supremacy in Community Mental Health.
Research highlights associations between adverse childhood experiences (ACEs) and workers' insomnia among Japanese adults. ACEs, including bullying and family dysfunction, are known to have detrimental health consequences.
Research found that selective serotonin reuptake inhibitor (SSRI) treatment for postnatal depression was associated with reduced child behavioral difficulties, ADHD symptoms, and maternal depression. The study also suggested long-term benefits of SSRI treatment on child outcomes up to five years after childbirth.
A study of over 4.4 million residents at 15,000 skilled nursing facilities found that telemedicine use was higher than pre-2020 levels and associated with improved access to psychiatry visits. Higher adoption rates were linked to better outcomes for patients in these facilities.
A randomized clinical trial found that exercise significantly reduced depressive symptoms and burnout in healthcare workers, while improving mental health. However, low adherence to exercise programming was noted towards the end of the study.
Researchers at Lund University discovered that psychedelic substances LSD and ketamine cause simultaneous synchronisation of neurons in several brain regions. This phenomenon is linked to the psychedelic experience and may hold clues for understanding psychoses and consciousness.
Researchers propose GABA-modulating treatments as potential therapeutic targets for depression's cognitive and affective symptoms. The study highlights the importance of GABA-A receptors in regulating balance and signals between neurons, and suggests compounds that promote or inhibit these receptors may alleviate depressive symptoms.
Researchers found that adults who experienced violence, financial stress, or separation from parents as children were more likely to experience physical and cognitive impairments. Adverse childhood experiences can have lifelong consequences, including difficulty walking, carrying out daily activities, and problems with memory.
A randomized controlled trial found that Nurse-Family Partnership improved child language and mental health at age 2, with no increase in child injuries or maternal pregnancies. The study involved 739 participants and their children for 2.5 years, providing new evidence on preventing early adverse childhood experiences.
Researchers found a clear pattern of suicidality related to the academic calendar, with peaks in April and October, but a decline during COVID-19 school closures. The study suggests interventions during peak months could help protect against seasonal increases in suicidality, especially for adolescent females.
A low-cost version of ketamine has shown strong results in treating treatment-resistant depression, with over 20% participants achieving total remission and a third experiencing symptom improvement. The study's findings bring definitive evidence to the field, which can be more affordable than existing treatments.
A new report suggests that AI-powered robot companions could alleviate the loneliness epidemic and its associated health risks. Companion robots have already shown promise in reducing stress and promoting physical and mental well-being in socially isolated older adults.
During the pandemic, acute care use for mental health conditions among youth increased notably, particularly among adolescent females. Prolonged boarding in emergency departments and waiting for inpatient psychiatric care are concerning trends that require interventions to address.
Researchers identified three neurobehavioral profiles that distinguish individuals with elevated mania vulnerability based on reward sensitivity and sleep-circadian characteristics. These profiles can help detect mania risk and provide targets for early interventions.
The USC PRECOG project aims to develop automated screening tools for clinicians using objective neural and physiological signal biomarkers. The team will advance interdisciplinary methods in neuroscience, linguistics, and machine learning to better understand mental health risk factors.
A new study finds nearly two-thirds of Medicare Advantage psychiatrist networks contain less than 25% of all psychiatrists, leaving many seniors without access to mental health care. The research suggests that this limited coverage may lead to higher out-of-pocket costs, delays in care, and foregone treatment.
Researchers at the University of Pittsburgh School of Medicine found no evidence that prescription stimulant treatment in childhood increases the risk of substance use disorder (SUD) later in life. The study, published in JAMA Psychiatry, suggests that stimulants are an effective treatment for ADHD with few side effects.
Researchers at Korea University Medicine identified a new neuroimaging-based biomarker for MDD, the local gyrification index (LGI), which shows decreased cortical folding in patients. LGI values reflect long-drawn developmental processes and are stable markers compared to previous biomarkers.
A study led by Lund University researchers found that brief admissions by self-referral can effectively reduce the need for acute visits, admissions, and longer treatment periods among adolescents with borderline personality disorder. The method empowers patients to determine when they need treatment, enhancing their autonomy and sense...
A new study from Aarhus University found that people with mental health issues are less likely to accept offers of colorectal cancer screening. The research showed that those with severe mental disorders had a 13.8 percentage point lower participation rate compared to those without mental illness.
Researchers used brain imaging to identify multiple subtypes of depression, finding distinct deviation patterns in functional connectivity among brain regions. This study provides leads for developing better treatments and personalized therapeutic interventions.
A study found that exposure to events against moral values and lack of confidence about raising safety concerns significantly contributed to staff distress. One-in-ten healthcare workers reported experiencing suicidal thoughts six months after completing a survey.
The Better Together trial partners with community organizations and sites to provide buprenorphine treatment, reducing distance for patients and offering peer support in familiar environments. Researchers aim to address barriers such as stigma, misunderstandings about addiction, and bias against certain treatments.
The use of psychedelics in mental health treatment is gaining traction, but concerns about patient safety and regulation need to be addressed. Psychedelic-assisted therapy shows promise in treating conditions like depression and PTSD, but more research is needed on dosages, settings, and guidelines.
A new pilot study published in JAMA Psychiatry demonstrates the potential role of probiotic supplementation in supporting mood and mental health in adults with Major Depressive Disorder. The study found significant improvements in depression and anxiety scores over an eight-week period, with notable benefits seen from week four onwards.
A new study found that LGB adults are more than twice as likely to experience suicidal thoughts or self-harming behaviors compared to straight peers. Depression, anxiety, and experiences of discrimination and bullying contribute to these increased risks.
The June issues of The American Journal of Psychiatry and Psychiatric Services focus on substance use disorders, opioids, and youth self-harm and suicide. The articles highlight the importance of addressing these issues to improve patient outcomes and reduce stigma.
A study found that nursing and clerical staff experienced higher levels of psychological distress due to fear of COVID-19. In contrast, physicians had higher resilience levels. The availability of in-hospital support and consultation on infection control also played a role in mitigating fear and stress.