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Stem Cells | Stem Cells News, Research and Current Events
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Tapping into spinal cures
Stem cells which give rise to vertebrae, muscle and the spinal cord have been identified for the first time by Dr. Valerie Wilson (University of Edinburgh). "These axial stem cells could be used in the future to help replace damaged tissues after back injuries", says Dr. Wilson who will... view more (2004-03-26)

Stem cell identity in culture may strongly depend on the cellular microenvironment
Identification, isolation and large scale culture of stem cells for potential medical applications is a major challenge in cell biology.   view more (2007-04-25)

Xie Lab demonstrates the role of microRNA pathway
Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary.   view more (2007-02-16)

Could skin cells become brain cells? (p 172)
Results of an experimental study in this week's issue of THE LANCET highlight how adult skin cells can be made into precursor nerve cells, with potential implications for the future treatment of neurodegenerative disorders such as Parkinson's disease. Ethical and practical considerations limit the... view more (2004-07-07)

U of MN researchers use human embryonic stem cells to kill cancer cells
For the first time, stem cell researchers at the University of Minnesota have coaxed human embryonic stem cells to create cancer-killing cells in the laboratory, paving the way for future treatments for various types of cancers (or tumors).   view more (2005-10-12)

U of MN researchers identify new cord blood stem cell
Researchers at the University of Minnesota Medical School have discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells.   view more (2006-02-14)

When is a stem cell not really a stem cell?
Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between "true" neural stem cells and similar, but less potent versions.   view more (2007-08-27)

Heart derived stem cells develop into heart muscle
Dutch researchers at University Medical Center Utrecht and the Hubrecht Institute have succeeded in growing large numbers of stem cells from adult human hearts into new heart muscle cells.   view more (2008-04-24)

Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become... view more (2007-06-18)

Statement from the European Life Sciences Group
The promises and concerns engendered by stem cell research triggered debate world-wide. European citizens realise the significance of these issues and expect guidance to deal with them. The European Life Sciences Group thanks the European Commission and the European Commissioner for Research,... view more (2001-12-19)

Scientists find stem cell switch
Scientists have discovered how plant stem cells in roots detect soil structure and whether it is favourable for growth.   view more (2007-07-27)

Ovarian cancer stem cells identified, characterized
Researchers at Yale School of Medicine have identified, characterized and cloned ovarian cancer stem cells and have shown that these stem cells may be the source of ovarian cancer's recurrence and its resistance to chemotherapy.   view more (2008-04-18)

Post brain injury: New nerve cells originate from neural stem cells
Most cells in the human brain are not nerve cells, but supporting cells (glial cells). They serve as a framework for nerve cells and play an important role in the wound reaction that occurs with injuries to the brain.   view more (2008-03-12)

Stem cells as cancer therapy
It is widely hoped that neural stem cells will eventually be useful for replacing nerves damaged by degenerative diseases like Alzheimer disease and multiple sclerosis. But there may also be another use for such stem cells-delivering anti-cancer drugs to cancer cells.   view more (2006-12-26)

New U of T strategy will boost cord blood stem cells
A team of bioengineers led by the University of Toronto has discovered a way to increase the yield of stem cells from umbilical cord blood, to an extent which could broaden therapeutic use of these cells.   view more (2005-10-19)

New stem-cell findings can help the body to cure itself
Researchers at Karolinska Institutet have identified an important mechanism that regulates how many new cells are produced by each intestinal stem cell. The study is published in the latest issue of the prestigious scientific journal, Cell.   view more (2006-06-16)

USC stem cell study sheds new light on cell mechanism
Research from the University of Southern California (USC) has discovered a new mechanism to allow embryonic stem cells to divide indefinitely and remain undifferentiated.   view more (2008-05-22)

Scientists make first step towards growing human lungs for transplant
Scientists have successfully converted human embryonic stem cells into lung cells, taking a first step towards building human lungs for transplantation.   view more (2005-08-23)

'It is time for scientists to make the case for stem-cell research' (p 113)
Stem-cell research-and its political, legal, and ethical implications-is the theme of this week's issue of THE LANCET. An editorial comments how scientists need to step forward and engage the public to make the case for the future benefits of stem-cell research. 'But convincing critics of the... view more (2004-07-07)

US funding for Lund research for project on adult stem cells
Adult stem cells are to be treated so that they develop characteristics of nerve cells and can produce dopamine, according to Associate Professor Jia-Yi Li at the Wallenberg Neuro Center at Lund University, who has received a grant of some SEK 2 million from the National Institutes of Health (NIH),... view more (2003-01-29)

Stem-cell therapy could have benefits and risks for heart-attack patients (pp 746, 751, 783)
Two studies in this week's issue of THE LANCET raise questions about the feasibility and safety of stem-cell therapy for heart disease, suggesting that such treatments could have both benefits and drawbacks. Adult haemopoietic stem cells give rise to blood cells, and are thought to be able to... view more (2004-03-03)

Isolation of a new gene family essential for early development
Researchers at BRIC, University of Copenhagen, have identified a new gene family (UTX-JMJD3) essential for embryonic development. The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of... view more (2007-08-23)

Dampened hopes for transplanting bone marrow stem cells in heart attacks
There is little, if any, evidence that adult stem cells can build other cells in an adult organism than those formed in the organs they themselves come from. At any rate, blood stem cells do not convert to heart muscle cells in a damaged heart, which was previously hoped. This has been shown by a... view more (2004-05-06)

Donor T cells change the fate of stem cells in transplantation
When a transplant patient suffers complications such as graft rejection or graft-versus-host disease, physicians attempt to stop the body's immune response by targeting a patient's T cells.   view more (2006-07-13)

Stem cells and cancer: cancer pathways that also control the adult stem cell population
Speaking today (10 April) at the UK National Stem Cell Network Annual Science Meeting in Edinburgh, Professor Alan Clarke from Cardiff University describes his work to investigate a mechanism that normally drives adult stem cells to repair the intestine.   view more (2008-04-10)

Master regulatory gene of epithelial stem cells identified
The skin's ability to replace the tissue it sloughs off is controlled by a variety of genes. A new study from Harvard Medical School published in the May 4 issue of Cell, however, identifies a "master regulator" of this regeneration process not only for skin, but for many epithelial... view more (2007-05-04)

Columbia University Medical Center researchers discover potential mechanism for tumor growth
Researchers at Columbia University Medical Center have identified an inherent feature of stem and progenitor cells that may promote initiation and progression of cancerous tumors.   view more (2005-12-16)

The European Science Foundation publishes policy briefing for human stem cell research
The policy paper recommends the permission of studies of stem cells from embryos and adults, reproductive cloning should not be permitted, but therapeutic cloning should be allowed. There are many chronic, serious and disabling human diseases such as, Parkinson's Disease, Cystic Fibrosis and... view more (2001-06-25)

Faults in newly discovered breast stem cells may lead to tumours
Victorian Breast Cancer Research Consortium scientists from The Walter and Eliza Hall Institute, using a mouse model, have discovered the rare stem cell that drives the formation of all breast tissue.   view more (2006-01-05)

Hopes for new cell therapies 'stem' from Sheffield
The Centre for Stem Cell Biology (CSCB) at the University of Sheffield is welcoming some of the world's leading experts to its International Human Embryonic Stem Cell Symposium on Friday 9 July 2004. The CSCB is a world-leading centre for stem cell research, and has produced two of the UK's six... view more (2004-07-06)

DFG remains skeptical of the cloning of human cells
According to a paper published in the journal Stem Cells, an American group has succeeded in inserting cell nuclei from human skin cells into human enucleated oocytes and to stimulate these new cells to undergo cell division in the laboratory.   view more (2008-01-23)

Progress being made in exploring potential use of stem cells to treat heart disease
Scientists are making headway in exploring the potential future use of stem cells to treat heart disease, according to a review article in the current issue of Nature (June 29, 2006).   view more (2006-06-29)

Treating male infertility with stem cells
New research has examined the usefulness of bone marrow stem cells for treating male infertility, with promising results. The related report by Lue et al, "Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure," appears in the... view more (2007-03-02)

UCLA researchers identify leukemia stem cells
Stem cell researchers at UCLA have identified a type of leukemia stem cell and uncovered the molecular and genetic mechanisms that cause a normal blood stem cells to become cancerous.   view more (2008-05-27)

ESC Congress 2004: Converting cells into heart muscle
Bone marrow derived stem cells can give rise to heart muscle cells. This plasticity concept - the ability of bone marrow cell to transdifferentiate into heart muscle cell - is supported by experimental and clinical data. Another possibility is to replace the missing function by causing... view more (2004-08-30)

Penn study finds hyperbaric oxygen treatments mobilize stem cells
According to a study to be published in the American Journal of Physiology-Heart and Circulation Physiology, a typical course of hyperbaric oxygen treatments increases by eight-fold the number of stem cells circulating in a patient's body.   view more (2005-12-29)

Discovery suggests why stem cells run through stop signs
Everyone knows that stem cells are controversial. Many people know that stem cells can grow into virtually any cell type found in the body, from a red blood cell to a muscle cell to a brain cell. But no one really knows why stem cells continue to divide and renew themselves long after the point... view more (2005-06-13)

Mechanism for regulation of growth and differentiation of adult muscle stem cells is revealed
During muscle regeneration, which is a natural response to injury and disease, environmental cues cause adult muscle stem cells (satellite cells) to shift from dormancy to actively building new muscle tissue.   view more (2007-12-10)

Signaling for cartilage
Skeletal progenitor cells differentiate into cartilage cells when one master gene actually suppresses the action of another, said Baylor College of Medicine researchers in a report that appears online in the journal Proceedings of the National Academy of Sciences.   view more (2006-11-28)

Researchers discover important tool in understanding differentiation in human embryonic stem cells
Researchers at the University of Minnesota's Stem Cell Institute have described how an existing genetic tool can be used to study how human embryonic stem cells differentiate. The research appears in the November 2007 issue of Experimental Biology and Medicine.   view more (2007-10-25)

USC researchers discover breast cancer stem cells in bone marrow
Almost all tumor cells found in the bone marrow of early stage breast cancer patients appear to be breast cancer stem cells, suggesting the risk of disease spread for all breast cancer patients may be greater than previously thought.   view more (2006-10-09)

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state
For more than 25 years, stem cells have been defined based on what they can become: more of themselves, as well as multiple different specialized cell types.   view more (2007-06-20)

UCLA researchers develop T-cells from human embryonic stem cells
Researchers from the UCLA AIDS Institute and the Institute for Stem Cell Biology and Medicine have demonstrated for the first time that human embryonic stem cells can be genetically manipulated and coaxed to develop into mature T-cells, raising hopes for a gene therapy to combat AIDS.   view more (2006-07-05)

Neural stem cells derived from human embryonic stem cells carry abnormal gene expression
Neural stem cells grown from one of the federally approved human embryonic stem cell lines proved to be inferior to neural stem cells derived from fetal tissue donated for research, a UCLA study has found.   view more (2006-08-07)

Researchers reveal repressor protein blocks neural stem cell development
A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons.   view more (2007-10-11)

UK leads race to produce world's first clinical grade stem cells
The University of Sheffield has received a £2.6m grant to create some of the world's first embryonic stem cell lines that can be used for medicinal purposes.   view more (2005-03-16)

Researchers link early stem cell mutation to autism
In a breakthrough scientific study published today in the Proceedings of the National Academy of Sciences, scientists at the Burnham Institute for Medical Research have shown that neural stem cell development may be linked to Autism.   view more (2008-07-01)

Cancer is a stem cell issue
There is an urgent reason to study stem cells: stem cells are at the heart of some, if not all, cancers.   view more (2007-02-20)

Cancer stem cells: know thine enemy
Stem cells -- popularly known as a source of biological rejuvenation -- may play harmful roles in the body, specifically in the growth and spread of cancer.   view more (2007-12-26)

Master regulatory gene found that guides fate of blood-producing stem cells
Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow.   view more (2005-08-02)
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