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Tapping into spinal cures
Stem cells which give rise to vertebrae, muscle and the spinal cord have been identified for the first time by Dr. Valerie Wilson (University of Edinburgh). "These axial stem cells could be used in the future to help replace damaged tissues after back injuries", says Dr. Wilson who will be presenting her work at the Society for... view more... (2004-03-26)
Stem cells which give rise to vertebrae, muscle and the spinal cord ... (University of Edinburgh). "These axial stem cells could be used in the future to help replace damaged ... - 2nd April). Unlike embryonic stem cells, axial stem cells may only differentiate into a limited number of tissues and ... At the moment the axial stem cells have only been grown ...

OU Cancer Institute Scientists Identify New Cancer Stem Cell Marker; Developing Drug to Stop Cancer Recurrence
After years of working toward this goal, scientists at the OU Cancer Institute have found a way to isolate cancer stem cells in tumors so they can target the cells and kill them, keeping cancer from returning.    view more (2008-09-12)
... a way to isolate cancer stem cells in tumors so they can target the cells and kill them, keeping cancer from returning. A research team led ... particular protein only appears in stem cells. Until now, researchers knew of proteins that appeared in both regular cancer cells and stem cells, but none that just identified a stem cell. The group has already begun ...

Stem cell identity in culture may strongly depend on the cellular microenvironment
Identification, isolation and large scale culture of stem cells for potential medical applications is a major challenge in cell biology.   view more (2007-04-25)
... and large scale culture of stem cells for potential medical applications is a major challenge in cell ... and computer simulations, that the stem cell identity in culture may strongly depend on the cellular ... a pre-programmed attribute of the cells. In practice, this work provide a rationale to research strategies ... to increase the efficiency of stem cell-related culture methods and, perhaps, ...

Xie Lab demonstrates the role of microRNA pathway
Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary.   view more (2007-02-16)
... for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary. The paper, "Dcr-1 Maintains Drosophila Ovarian Stem Cells," was published on the Web site of Current Biology today. ... self-renewal of two types of stem cells in the Drosophila ovary. "The findings were interesting to us ... maintenance of two types of stem cells —germline stem cells ...

Could skin cells become brain cells? (p 172)
Results of an experimental study in this week's issue of THE LANCET highlight how adult skin cells can be made into precursor nerve cells, with potential implications for the future treatment of neurodegenerative disorders such as Parkinson's disease. Ethical and practical considerations limit the availability of neural stem cells derived from... view more... (2004-07-07)
... LANCET highlight how adult skin cells can be made into precursor nerve cells, with potential implications for the future treatment of neurodegenerative disorders ... limit the availability of neural stem cells derived from human embryonic tissue. A readily available source of human neural stem cells is therefore needed. Siddharthan Chandran (University of Cambridge, UK) and ... UK) and colleagues used skin cells ...

Scientists can now differentiate between healthy cells and cancer cells
One of the current handicaps of cancer treatments is the difficulty of aiming these treatments at destroying malignant cells without killing healthy cells in the process.   view more (2009-01-06)
... these treatments at destroying malignant cells without killing healthy cells in the process. But a new study by McMaster University ... cancer, while sparing normal healthy cells Mick Bhatia, scientific director of the McMaster Stem Cell and Cancer Research Institute in the Michael G. DeGroote ... - the difference between normal stem cells and cancer stem cells in humans. The discovery, published in the ...

A link between mitochondria and tumor formation in stem cells
Researchers report on a previously unknown relationship between stem cell potency and the metabolic rate of their mitochondria -a cell's energy makers. Stem cells with more active mitochondria also have a greater capacity to differentiate and are more likely to form tumors.   view more (2008-10-13)
... a previously unknown relationship between stem cell potency and the metabolic rate of their mitochondria -a cell's energy makers. Stem cells with more active mitochondria also have a greater capacity to ... methods of enriching the best stem cells from a population for therapeutic use and may provide some ... insights into the role of stem cells in cancer. This study, conducted by ...

U of MN researchers use human embryonic stem cells to kill cancer cells
For the first time, stem cell researchers at the University of Minnesota have coaxed human embryonic stem cells to create cancer-killing cells in the laboratory, paving the way for future treatments for various types of cancers (or tumors).   view more (2005-10-12)
For the first time, stem cell researchers at the University of Minnesota have coaxed human embryonic stem cells to create cancer-killing cells in the laboratory, paving the way for future treatments for ... Immunology. Researchers generated "natural killer" cells from the human embryonic stem cells. As part of the immune system, natural killer cells normally are present in the blood stream ...

U of MN researchers identify new cord blood stem cell
Researchers at the University of Minnesota Medical School have discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells.   view more (2006-02-14)
... discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells. Umbilical cord blood is generally known to contain hematopoietic stem cells that can only produce cells found in blood. The new findings, however, identify a small ... small population of cord blood cells with the characteristics of more primitive stem cells that have ...

When is a stem cell not really a stem cell?
Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between "true" neural stem cells and similar, but less potent versions.   view more (2007-08-27)
... to distinguish between "true" neural stem cells and similar, but less potent versions. Their finding, reported this ... could simplify the isolation of stem cells not only from brain but also other body tissues. What the ... that appears to prevent neural stem cells - the sort that might be used to rebuild a ... to rebuild a damaged nervous system - from taking ...

Heart derived stem cells develop into heart muscle
Dutch researchers at University Medical Center Utrecht and the Hubrecht Institute have succeeded in growing large numbers of stem cells from adult human hearts into new heart muscle cells.   view more (2008-04-24)
A first in stem cell research Dutch researchers at University Medical Center Utrecht and the ... in growing large numbers of stem cells from adult human hearts into new heart muscle cells. A breakthrough in stem cell research. Until now, it was necessary to use embryonic stem cells to make this happen. The findings are published in the ... latest issue of the ...

Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual... view more... (2007-06-18)
... disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small ... small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual ... a small subset of cancer stem cells, which they have shown share the same protective mechanisms as normal lung stem cells. They are presenting ...

Statement from the European Life Sciences Group
The promises and concerns engendered by stem cell research triggered debate world-wide. European citizens realise the significance of these issues and expect guidance to deal with them. The European Life Sciences Group thanks the European Commission and the European Commissioner for Research, Philippe Busquin, for arranging such a stimulating... view more... (2001-12-19)
... promises and concerns engendered by stem cell research triggered debate world-wide. European citizens realise the significance ... such a stimulating meeting on "Stem cells: Therapies for the Future?" and thereby contributing to the ongoing ... The current research on human stem cells, either from differentiated tissue or from embryos, is scientifically sound ... Although the use of human stem cells in regenerative medicine ...

Scientists find stem cell switch
Scientists have discovered how plant stem cells in roots detect soil structure and whether it is favourable for growth.   view more (2007-07-27)
Scientists have discovered how plant stem cells in roots detect soil structure and whether it is favourable ... regulates cell division in root stem cells. Ethylene is known to play a role in perceiving and ... Professor Dolan. As in humans, plant stem cells are the source of all growth. The defining characteristics of stem cells are that they are able to either ...

Ovarian cancer stem cells identified, characterized
Researchers at Yale School of Medicine have identified, characterized and cloned ovarian cancer stem cells and have shown that these stem cells may be the source of ovarian cancer's recurrence and its resistance to chemotherapy.   view more (2008-04-18)
... characterized and cloned ovarian cancer stem cells and have shown that these stem cells may be the source of ovarian cancer's recurrence and its ... tumors are made up of cells that are both cancerous and non-cancerous. Within cancerous cells, there is a further subclass referred to as cancer stem cells, which can replicate indefinitely. "Present chemotherapy modalities eliminate the bulk of ...
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