A study published in JAMA found that postmortem genetic testing can identify the likely genetic cause of death in cases where it was not determined. The analysis sequenced DNA from deceased individuals and their relatives, discovering mutations linked to sudden cardiac death, pulmonary embolism, and other conditions.
A team of researchers from ETH Zurich has discovered that a specific subset of blood cells - the regulatory T cells - can suppress lymphedema. This finding could help develop therapies to cure lymphedema by targeting inflammatory responses.
A team from Georgia State University has won a $2 million federal grant to improve mental health services for child victims of commercial sex trafficking. The project will expand therapy programs and train therapists working in juvenile justice and foster care systems.
Scientists at the University of Vienna have developed a new technique to measure isotopes in nanometer-sized areas of materials, revealing atomic-resolution electron microscopes can distinguish between different isotopes of carbon. This method can be extended to other two-dimensional materials and has the potential to improve synthesis.
Senator Mark Warner will receive the SURA Distinguished Friend of Science Award for his efforts to advance collaborative research and education. The award recognizes his commitment to fostering innovation and increasing support for science investments, including a successful restoration of funding for the Jefferson Lab.
Patients diagnosed with cancer at emergency presentation have poorer survival rates compared to those diagnosed electively. The review highlights inequalities in socioeconomic groups and ethnicity, emphasizing the need for new screening methods and improved participation in existing screening programs to reduce emergency presentations.
Researchers at Johns Hopkins Medicine identified a protein that enables toxic alpha-synuclein aggregates to spread in the brain. A treatment strategy blocking this protein's action may slow Parkinson's disease progression, as antibodies already in clinical trials for cancer therapy show protective effects.
A field study found pesticide exposure can impact bumblebee colonies, reducing queen and male production, which underpins colony success. The study provided a controlled method to assess long-term effects of pesticides on colony health.
Researchers have demonstrated that horizontal gene transfer may play a major role in compensating for genome reduction in endosymbionts. This process involves the acquisition of genes from neighboring bacteria through horizontal gene transfer, which fills gaps in organelle-localized biosynthetic pathways.
Aerobic exercise improves glycemic control and reduces insulin requirements in T1D patients. The study found that physically active patients had more responsible behavior in monitoring their glucose levels, suggesting an educational program addressing diet, insulin injecting monitoring, and exercise could be highly advantageous.
Researchers from FAU and Freie Universität Berlin have synthesised an iron compound in the rare oxidation state +4, a milestone in synthetic chemistry. The new molecule exhibits unique structural properties due to supramolecular interactions between ions.
A successful trial shows that taking oral tablet Sunitinib for one year reduces the likelihood of kidney cancer returning for patients following removal of the kidney. The treatment improves disease-free survival and reduces the risk of relapse by 40-50% compared to placebo.
Scientists have discovered a new species of fossil crocodile that had complex, mammal-like teeth, which allowed it to crunch through the exoskeletons of insects. The tiny 'crocodile' was less than 2 feet in length and lived in the Kem Kem Beds in Morocco during the Cretaceous period.
Researchers found a phage carrying animal-like DNA related to the black widow spider toxin gene, which also shares DNA with animal genomes. This discovery may provide insights into genetic engineering Wolbachia to fight diseases.
UTA researchers have earned two grants to install longer-lasting fiber-reinforced concrete pipes in Texas and develop a 100-year service life protocol for Florida. The new standard describes a technically strong and durable reinforcement option that can be used for underground piping, with excellent long-term performance observed.
A modeling study suggests that supplementary vaccination campaigns triggered by measles outbreaks could prevent 28,613 cases over 15 years in high-incidence settings. Vaccination campaigns prompted by serological surveys could prevent more cases, but would need to occur annually in high-incidence settings.
New research published in Clinical Infectious Diseases reveals that infection with Zika virus during pregnancy can lead to brain damage in infants born prematurely. In another study, scientists found Zika virus in patients receiving organ transplants, highlighting a new complication of the disease.
Researchers discovered that naked mole-rats' unique TrkA receptors alter protein building blocks, reducing signal-relaying action and making them insensitive to thermal hyperalgesia. This finding may lead to new pain therapies by blocking NGF and TrkA interactions.
A study found that Medicaid expansion in 2014 led to a decline of $2.8 million in average annual uncompensated care costs per hospital, while increasing Medicaid revenue by $3.2 million annually. Hospitals in states with Medicaid expansion also experienced improved excess margins, but not operating margins.
Researchers have developed an ultrafast technique to film the propagation of guided light and read its spatial profile across a multilayered structure. This breakthrough enables the design and control of confined plasmonic fields, crucial for future optoelectronic devices.
A new study from Purdue University found that exposing preschool children to simple math concepts, such as 'more' and 'fewer', can improve their mathematical skills. The study showed that children who participated in small groups discussing age-appropriate mathematical language scored higher on math tests than those who did not.
Researchers have generated femtosecond pulses in mid-infrared wavelengths, opening opportunities for research in physics, chemistry and biomedicine. The new technique allows scientists to study atomic processes taking place in atoms, molecules and solids with unprecedented speed.
Researchers have developed methods to control defects in graphene, which can lead to improved membranes for water desalination and energy storage. Simulations using the Reactive Force Field Method predict interactions between atoms and defects, enabling controlled defect formation.
Scientists at the University of Birmingham discovered a previously unknown mechanism connecting transcription machinery to genetic mutations in aggressive cancer cells. The research found that increased transcription activity leads to R-loop formation, causing DNA damage and replication stress.
The DFG is funding seven new research units with a total of approximately €15 million. The units will focus on various topics such as building design, metal-organic frameworks, and autoimmune diseases like pemphigus. The funding will enable researchers to pursue current issues in their fields and establish innovative directions.
Kytai Nguyen, a nationally recognized professor of bioengineering at UTA, has overcome numerous challenges in her life and career. She was awarded the inaugural Embracing Challenge Award from Materials Today magazine for her perseverance and contributions to new knowledge in materials science and engineering.
A study of 81 men found that those with nurturing childhood environments were more likely to have secure attachments to their romantic partners late in life. This association was partially explained by better emotion regulation skills in midlife, which predicted more secure marriages.
Researchers developed a smart textile that can sense and move like a muscle, enabling new device applications. The textile generates a mechanical work capacity and power output higher than human muscles, with potential uses in robotics, sensors, and smart clothing.
The University of New Hampshire will study ocean ecosystems using underwater acoustic technology in the mid- and south Atlantic Ocean. The research aims to understand patterns and trends in regional ocean soundscapes and processes, including climate change.
Research shows that mothers respond strongly to moral faults in their infants, using high-intensity interventions like physical restraint and commands. In contrast, pragmatic and prudential transgressions are met with lower-intensity responses. Infants are more likely to comply with moral commands and less likely to protest verbally.
Researchers at the Wyss Institute have successfully bioprinted a functional 3D renal architecture that recapitulates key functions of the kidney, including nutrient reabsorption. The printed tissue is composed of living human epithelial cells and has been sustained for over two months in vitro.
A new study by Thomas Jefferson University shows that community outreach workers may help increase hepatitis B vaccine uptake among Asian Americans, reducing the risk of liver cancer. The program involved lay health workers who provided personalized calls to encourage vaccinations.
Researchers found that direct livestock-transfer programs had a rapid and persistent positive effect on poverty and food insecurity, increasing dietary diversity and economic resilience. The programs also improved gender empowerment and reduced poverty among participating households.
Researchers at the University of Copenhagen discovered that trust building is key to emerging a robust communication network, even in standardized and impersonal settings. The experiment, called 'The Expert Game', found that strong network connections formed between participants when they were tied to monetary gain.
A team of Shanghai Jiao Tong University researchers developed antireflective structures capable of suppressing visible light at different angles of incidence. The structures, inspired by cicada wings, were fabricated using titanium dioxide and show great potential for photovoltaic devices like solar cells.
Ferns are inaccurately depicted as extreme inbreeders in most biology textbooks, but research suggests this is not the case. New study co-authored by KU researcher Christopher Haufler reveals that ferns use outbreeding to produce genetic variation, contrary to long-held assumptions.
A recent study found a connection between follicular T helper cells and the development of type 1 diabetes. The cells were increased in frequency close to disease onset, particularly in children with multiple autoantibodies.
Ancient leaves reveal that carbon dioxide levels increased dramatically as the ice sheet began to deteriorate, raising questions about its stability today. The study found a rapid decline in ice extent over a short period, similar to modern times, where CO2 concentrations are rising.
Researchers successfully boosted regeneration of mature nerve cells in the spinal cords of adult mammals, increasing the number of newly matured neurons by tenfold. The approach involves silencing the p53-p21 protein pathway and adding growth factors to boost neuron production.
Researchers have developed a new platform using whole animal models that can speed up scientific research and accurately assess the effectiveness of new drugs for neurodegenerative diseases. The platform, which uses roundworms, can analyze thousands of live animals simultaneously and at high speeds.
Researchers have identified a unique insect with characteristics from various insects but no known relatives. The 100-million-year-old wingless wasp, named Aptenoperissus burmanicus, belongs to the newly created family Aptenoperissidae within the order Hymenoptera.
The Pitt Urology Department has been awarded $7.7 million to investigate BPH and LUTS, aiming to develop novel preventative and therapeutic approaches. The center will focus on inflammation involved in these conditions.
Researchers found that a new casting technique called close contact casting can reduce the need for surgery in elderly patients with unstable ankle fractures while minimizing drawbacks of traditional casts. The study compared outcomes between close contact casting and traditional surgical treatment.
A study by Dartmouth Health found that children genetically predisposed to obesity overeat when exposed to TV food ads. The study showed a significant increase in calorie consumption among children who watched food commercials compared to those who watched toy ads.
Scientists identified noncoding mutations that disrupt cooperative function of 'gene families' in Hirschsprung's disease, a rare genetic disorder. The study suggests that dysfunctional gene networks may influence other complex diseases, such as cancer and diabetes.
A UTA civil engineering professor has secured a $1.2 million contract with TxDOT to implement a system that improves sub-base repair of roads, reducing pavement cracking and improving maintenance. The team will also use recycled plastic pins for slope stabilization in around TxDOT's Dallas District.
Research by George Washington University researchers found a special amplifier that boosts weak neural signals in the developing brain, allowing for accurate information transfer. This unique amplification circuit is thought to be responsible for the differing levels of seizures in young and old individuals.
New research reveals that a small change in the naked mole rat's TrkA receptor makes it less sensitive to pain signals, allowing them to survive in crowded underground colonies. This adaptation may help conserve energy and aid in thermoregulation.
A new study finds that migrants arriving on visas to the UK from countries at high risk of TB pose a negligible risk of onwards infection, despite being at increased risk of developing TB themselves. Ongoing monitoring and treatment are crucial to continuing the downward trend of TB incidence in the UK.
A team of researchers has successfully demonstrated the synchronization of optical clocks across a low-lying, strongly turbulent, 12-km horizontal air path using a frequency comb. They achieved femtosecond-level clock synchronization by measuring the arrival time of pulses at each site and correcting for the finite speed of light.
Researchers at Barrow Neurological Institute have identified a link between domestic violence and traumatic brain injury, with 88% of victims suffering more than one head injury. The study aims to expand awareness and treatment options for domestic violence survivors, who often lack access to resources.
Research on Asian American children and youth highlights key aspects of diversity within the group, including culture, language, socioeconomic status, and immigration experiences. Studies reveal variations in poverty rates, bullying rates, and academic outcomes among subgroups, emphasizing the need for culturally sensitive measurement.
Researchers at Rice University have created a laser-free, wireless system capable of delivering 1 terabit of data per second using pulse-radio technology inspired by Guglielmo Marconi. This breakthrough technology promises to revolutionize wireless communication with speeds 20,000 times faster than current 4G networks.
A new study reveals the cellular mechanisms that help human mesenchymal stem cells (hMSCs) retain their therapeutic properties when cultured in the lab. Mitochondria play a central role in this process.
PharmaMar's Phase 2 study shows significant reduction in tumor size and improved survival rates for patients with BRCA 1/2 metastatic breast cancer. The trial achieved an overall response rate of 41% with a 61% response rate in the BRCA 2 subgroup.
Researchers studied the distribution and characteristics of natural gas hydrates in fine-grained sediments from Shenhu area, South China Sea. They found that foraminifera shells played a crucial role in increasing porosity and hydrate accumulation.
The University of Melbourne team created a quantum molecular microscope to image individual atoms in bio-molecules, overcoming issues with conventional biomolecule imaging. The system uses atomic-sized qubits as highly sensitive quantum sensors to capture high-resolution images.
A comprehensive analysis of 77 studies found no difference in the work ethic between baby boomers, Generation X, and Millennials. The findings suggest that organizational initiatives targeting generational differences may be unwarranted.
A high-protein diet eliminates improvements in insulin sensitivity after weight loss in obese postmenopausal women. Women who consumed more protein lost less lean tissue, but the total difference was only about a pound.
A national survey of state mental health directors reveals poorly organized state agency structures, workforce shortages, limited accessibility, and stigma concerns are hindering improvements in children's mental health care. The survey highlights the need for increased public awareness and understanding to increase access to services.