Researchers have discovered new genes associated with the development of pheochromocytomas and paragangliomas, which are rare neuroendocrine tumors with a strong hereditary component. The study identifies alterations in enzymes involved in cell respiration as a key factor in tumor growth.
A team of UC researchers is using gene editing to develop a new method to control disease-spreading mosquitoes, focusing on the Aedes aegypti mosquito. The Safe Genes project aims to introduce genetic elements that rapidly spread throughout a population, reducing the mosquito population and preventing disease transmission.
A recent study found that air travel stress has no effect on search and rescue dog job performance, but alters the canine microbiome. Despite physiological impacts, dogs overcome stress to save lives.
African-American Muslim women's breastfeeding rates are low, with less than 62% initiating and 14% exclusively breastfeeding for six months. Engaging Islamic teachings through community education may increase breastfeeding exclusivity and duration.
The University of Sussex is conducting vital skin cancer research with a new £428K grant. The project focuses on targeting the PHIP(2) protein, which is present in high amounts in melanoma and other aggressive cancers.
Researchers found that Przewalski's horses, now protected in the Gobi Desert, consume only high-quality grass throughout the year due to improved human attitudes. In contrast, Khulan wild asses also live in the same habitat but are still hunted and have a more restricted diet.
A new study found that patients with lower immune cell numbers, particularly those with exhausted T cells, benefit most from combination immunotherapy. Researchers developed an assay to measure immune cell populations and predict patient responses.
A new study uses Google search data to track dengue fever in underdeveloped countries, providing accurate and timely estimates of disease prevalence. The method, called ARGO, combines Google Trends data with government-provided clinical data to alert governments and hospitals when elevated dengue incidence is anticipated.
Research at Florida Atlantic University reveals that slower boat speeds do not reduce risks to manatees, but instead cause more harm. An innovative alerting device is proven to deliver a better solution, projecting low-intensity sounds that deter manatees from approaching boats.
Researchers found HIV-1 integrates its genetic material into specific immune-cell-activating genes in humans. Digoxin inhibits wild type HIV-1 more than the mutated strain, suggesting a link between T cell activation and targeted integration.
Loma Linda University researchers found four factors associated with decreased body mass index: single or dual meals, overnight fasting up to 18 hours, breakfast instead of skipping it, and making breakfast the largest meal of the day. Making breakfast the largest meal resulted in a more significant decrease in BMI compared to lunch.
A molecular analysis of tissue mismatch between donors and recipients predicted which recipients needed high doses of immune modulating drugs. The study found a strong correlation between low medication levels and low molecular mismatch scores, allowing physicians to tailor treatment to individual patients.
A study by MD Anderson Cancer Center found improved survival rates for patients with stage 3 lung cancer treated with concurrent chemotherapy and proton therapy. The treatment reduced toxic effects compared to standard care, with a median overall survival of 26.5 months.
A Cornell-led project has identified modern, ancient, and heritage wheat varieties best suited for organic growing in the Northeastern and north-central climates. The results show that these varieties are in high demand, with consumers willing to pay more for bread, pasta, and baked goods made from them.
A Massachusetts General Hospital study found that fMRI and EEG can identify covert consciousness in ICU patients, allowing families to make informed decisions about care. The tests detected activity in higher-order cortex areas of the brain, which could have implications for patient recovery.
Researchers study brain-movement interaction in mice to understand how cells in the motor cortex communicate with muscles. The findings reveal that neurons pulse similarly to those around them, driving one type of movement over another.
Researchers at the University of Warsaw have developed a method to form colloidal chains by pulling out individual particles from a suspension using an electrode. The chains are held together by a thin layer of liquid, and their flexibility is influenced by the type of liquid used.
A study published in Journal of Environmental Management found a direct correlation between shale gas development activity and the rapid invasion of non-native plant species in Pennsylvania's northern forests. The research suggests that invasive plants can alter forest ecosystems, affecting wildlife habitats and timber harvests.
Fernanda has weakened from its peak wind speed of 143.75 mph, now with maximum sustained winds near 70 mph and higher gusts. The storm is expected to continue moving west-northwest for the next couple of days before potentially becoming a tropical depression.
Research found that cohabitating couples share similar skin microbiomes, especially on their feet, and that biological sex can be identified based on certain body regions
Small mountain glaciers play a significant role in recharging vital aquifers and keeping rivers flowing during the winter. A new study found that these glaciers contribute up to 66% of annual flow in mountain streams, highlighting their importance in maintaining ecosystem processes.
A new therapy called 3MDR is being investigated for its effectiveness in treating British military veterans with treatment-resistant and combat-related PTSD. Researchers aim to help patients approach their traumatic memories through walking on a treadmill while interacting with self-selected images.
A global data set reveals that volcanic arcs mobilize carbon from crustal carbonate platforms, particularly in Italy and Indonesia. This finding requires a downward revision of past organic carbon burial estimates.
Researchers at University of California San Diego School of Medicine have been awarded a $5.8 million CIRM grant to develop an immunotherapy that targets cancer stem cells using CAR T-cell therapy. The treatment aims to improve the ability of immune cells to target and kill multiple types of cancers.
A new study by University of Toronto researchers found that hiring chief risk officers (CROs) actually increased risky behavior in US banks, leading to the 2008 financial crash. Banks with CROs were more likely to use high-risk derivatives, while safer options were used less.
The European Society for Medical Oncology has announced the recipients of its four distinguished annual awards. Miguel Martin is recognized for his work in breast cancer research, while José Baselga receives the Lifetime Achievement Award for pivotal contributions to drug development. Alberto Bardelli wins the Translational Research Aw...
A new study in Marketing Science found that consumer responses to mobile promotions are higher and faster in sunny weather than cloudy weather. The study suggests that firms can use local weather information to improve the effectiveness of their mobile ads, with better-than-yesterday or forecasted sunshine boosting purchase responses.
A study from the Journal of Dairy Science found that consumers prioritize healthy options and taste when choosing between milk and nondairy beverages. The results highlight the importance of education on nutritional value and correcting misconceptions to broaden the appeal of dairy milk.
A study by Stanford scholars found that people who believe they are less active than peers die younger, even if their actual activity levels are similar. This suggests that mindsets play a crucial role in health outcomes.
Researchers have developed a method to quickly diagnose preeclampsia, which affects 5% of pregnancies and is linked to elevated fetal hemoglobin levels. The findings may lead to better diagnostics and treatments for affected women.
Researchers at Dartmouth's Norris Cotton Cancer Center have discovered a novel synthetic lethality screen to discover molecules that target genetically modified yeast lacking NF1. The team identified one lead candidate called Y100, which disrupts tumor cell growth and induces oxidative stress causing death of NF1-deficient cancer cells.
Researchers found that age is the most strongly associated breast cancer risk factor with normal breast DNA methylation differences. The study characterized molecular differences in healthy tissues that may contribute to cancer risk, providing insight into how epigenetic dysregulation contributes to breast cancer.
Researchers developed a model predicting heart cells' ability to produce ATP and stay alive under low oxygen conditions. The study found that even severely depleted regions of the heart can maintain ATP levels using energy reserves until oxygen approaches zero, but eventually crash when backup reserves shut down.
A new Northwestern University study suggests that paying people to conserve their trees could be a highly cost-effective way to reduce deforestation and carbon emissions. The program, known as Payments for Ecosystems, was found to have large impacts on forest cover in western Uganda.
A study of 13,864 participants found no convincing evidence linking PPI use to increased dementia risk. The research suggests that PPIs are safe for patients who require them for long-term treatment, and benefits may outweigh risks.
HIV-associated neurocognitive disorders (HAND) affect approximately one in four people living with HIV, causing symptoms such as memory loss and cognitive decline. Researchers have found elevated levels of microRNAs affecting brain development, providing a potential biomarker for diagnosis and monitoring disease progression.
Researchers found significant discrepancies in how potential donors are evaluated and identified across the US. They propose two new metrics: evaluating donation percentage and tracking organs transplanted per possible donor, which could help identify high-performing OPOs and improve donation rates.
Research suggests that cognitive abilities in grandmothers may have contributed to the emergence and evolution of menopause. Computer simulations found that caring for existing children and grandchildren provided an evolutionary advantage, increasing fertility and survival rates.
Researchers found that active users are more likely to be denialists, with a core group promoting denialist views and recruiting support through interactions. The study identified a high-risk group of over 1,000 users, including those who interact with the core and are influenced by their views.
Researchers have found firm evidence of Majorana fermions in lab experiments on exotic materials. The discovery is significant as it confirms one of the most intensive searches in fundamental physics.
Research by American Psychological Association finds that people who think they're less active than peers have a greater chance of dying younger. The study controlled for actual activity levels and found a significant correlation between perceived physical activity and mortality.
Researchers have discovered a way to estimate black hole masses by looking at spiral galaxy arms. The study found that galaxies with tightly wound spiral arms tend to have more massive black holes.
Researchers developed a new combined PET-CT scan technique that diagnoses cardiac sarcoidosis more accurately, revealing secondary sites in 40% of patients. The technique uses a 72-hour high-fat diet to provide clearer images and better detect the disease.
A new study led by Roland Geyer estimates that over 8 billion metric tons of plastic have been produced since the 1950s, with most becoming waste after four years. The research provides a global analysis of plastic production and fate, highlighting the need for sustainable materials management.
Researchers found that northern elephant seal males use the memory of rhythmic patterns to identify rival calls, distinguishing between subtle changes in tempo and tone. This ability is crucial for their survival, allowing them to choose strategies in mating and territorial battles.
Researchers found that disrupting gut microbes in tadpoles affects adult frogs' ability to fight parasitic infections. A healthy bacterial community may confer protection against diseases later in life. The study's findings have implications for understanding the immune systems of mammals and humans.
A study by Queen Mary University of London found that training clinicians to ask about domestic violence in sexual health clinics can be feasible and increase referrals to specialist services. The risk of gynaecological and sexual health problems is three-fold higher in women who have suffered domestic violence.
A major stormfront study reveals shifting storms bring unprecedented danger from climate change, damaging waterfront areas once thought safe. The study found 11.5 million cubic metres of sand eroded in just three days, equivalent to filling the Melbourne Cricket Ground seven times.
A University of Guelph-Humber funded study found that a strong ethno-cultural identity and connection to the land are significant factors in positive mental health outcomes. The Cree community showed lower rates of depression, suicide, and mental illness despite shared history of trauma.
Researchers propose a new approach to measure river ecosystem functionality, integrating process measurements to assess ecological status. The study synthesizes existing processes, criteria of use, and sensitivity to environmental stressors, offering a tool for researchers and managers.
Researchers found that hematopoietic stem cells can directly detect bacterial infections and begin dividing without signals from growth factors. This reaction damages the cells' regenerative ability, potentially leading to malignant diseases at advanced age.
A University of Houston researcher is developing a system that would allow security cameras to recognize and send an alert at the first sign of a threat to public safety. The project uses video analytics to build mathematical models that reflect human behavior and predict deviations from the norm.
Researchers have made a breakthrough in genetically engineering microalgae found in corals to enhance their stress tolerance and prevent coral bleaching. This could be a game-changer for ocean productivity and global coral reef conservation.
USC researchers found that disinformation campaign on MacronLeaks was mostly consumed by foreigners on social media, with 18% of promoters being bots. The campaign's impact on French voters appeared to be limited despite being tweeted nearly 350,000 times.
A study sequenced genomic DNA of Ashkenazi Jewish women with breast cancer, revealing a higher prevalence of non-BCRA mutations in BRCA1 and BRCA2. The findings suggest that genetic testing for all breast cancer genes may benefit these patients.
A new longitudinal study found that 32% of young adult cancer survivors experience consistently low social functioning over time. The researchers highlight the need for support programs and screening at diagnosis to address these challenges.
Biomedical engineers found that different beta subunits attach to the main protein in a unique way, affecting the channel's control over the heartbeat. This discovery could lead to precision medicine and therapies tailored to individual needs.
A large clinical trial found that the high-dose flu vaccine significantly reduced hospitalization rates among nursing home residents, with a relative risk of hospitalization being 12.7 percent lower for the high-dose group. The vaccine also appeared to help prevent hospitalization for other problems, including cardiovascular symptoms.
Scientists have found evidence that the soil microbiome in restored Illinois prairies is recolonizing and recovering, closely resembling those in untouched natural prairies. This discovery suggests that restoration efforts are working at a foundational level, contributing to the health of people and the planet.
A team of researchers has made the best measurement yet of molecular gas, a raw material for star formation, in three massive galaxy clusters in the early universe. The study found that cluster galaxies have more fuel available to form stars than previously thought.