Biomaterials with precisely ordered structures could be used for various biomedical applications due to their precise control of self-assembly. The hybrid approach allows researchers to expand the chemical diversity of protein-based materials by combining different alphabets, such as amino acids and lipids.
Researchers have discovered nine new genes associated with osteoarthritis, a degenerative disease causing joint damage and pain. The findings could lead to the development of targeted therapies for this debilitating condition, affecting 10 million people in the UK.
A new study projects that cutting carbon emissions sooner could avoid up to 153 million premature deaths globally, with the greatest gains in Asia and Africa. Cities like Kolkata and Delhi, India, could see up to 4.4 million projected saved lives.
Researchers found that using a single corticosteroid and long-acting bronchodilator treatment for both daily asthma control and rescue relief is more effective than separate medications. This approach significantly reduces asthma attacks, hospitalizations, and emergency room visits.
Researchers present a modified small-molecule drug that targets the RNA polymerase subunit of the influenza virus, reducing its ability to replicate and spread. The compound could potentially eliminate the virus or slow down its reproduction, offering a new treatment option for patients with flu.
A study by EMBL researchers found that over a quarter of non-antibiotic drugs inhibit the growth of at least one species in the human gut microbiome. This can lead to unintended side effects and potentially contribute to antibiotic resistance. The research team screened 1000 marketed drugs against 40 representative bacteria, revealing ...
A third of recent high school graduates have ridden in a motor vehicle with a substance-impaired driver, according to a study by researchers at the National Institutes of Health. The study found that 23% of young adults had ridden with marijuana-impaired drivers, while 20% had ridden with alcohol-impaired drivers.
Researchers at UCSB developed a specially engineered retinal patch using stem cells to treat people with sudden severe sight loss from wet AMD. The study showed improvements in vision, enabling patients to read and perform daily tasks.
Immunotherapy has shown promising results in treating metastatic breast cancer, with a median progression-free survival of 33 months and median overall survival of 82 months. The treatment has been found to improve PFS and OS in both luminal and non-luminal subtypes, offering new hope for patients with this incurable disease.
Researchers found that children with obesity who exhibited higher levels of impulsivity lost more weight during family-based behavioral treatment than those who were less impulsive. The six-month program aimed to change parent and child behaviors, including eating habits and physical activity.
Researchers have identified useful commercial applications for grape waste, such as prolonging the shelf life of fatty foods. Grape pomace is rich in natural antioxidants like proanthocyanidins, anthocyanins, and ellagic acid, which can be used to substitute artificial antioxidants in food products.
Researchers analyzed animal remains from Ceibal, Guatemala, and found that dogs, turkeys, and cats were raised for ceremonial purposes, with dogs being traded across the landscape. The study sheds light on the role of animals in Maya civilization and challenges previous assumptions about their management.
A groundbreaking study found that people can correctly identify others' feelings up to 75% of the time by analyzing subtle changes in blood flow color around the nose, eyebrows, cheeks, or chin. Computer algorithms developed from the research accurately recognize human emotion via face color with up to 90% accuracy.
Deborah Blum received the Endocrine Society's Award for Excellence in Science and Medical Journalism for her article examining how natural compounds in soy can interfere with estrogen hormones in the body. The study highlights the potential health risks associated with EDC exposure, including reproductive disorders and cancer.
Researchers observed the full range of superconducting states from insulator to superconductor and back to re-entrant insulator in a WS2 monolayer. The discovery could lead to rational design of 2D superconducting devices at relatively high temperatures.
A study published in Nature Genetics has identified nine novel genes associated with osteoarthritis. Researchers used the UK Biobank resource and found that five of these genes differ significantly in their expression between healthy and diseased cartilage, offering new targets for future research into therapies.
Researchers established two new adrenal cancer cell lines and mouse models to test novel treatments, identifying PBK as a key target. A patient treated with pembrolizumab showed remarkable response with 77% tumor reduction, while a humanized mouse model also responded to the immunotherapy.
Human habitat alteration leads to global phylogenetic homogenization, replacing diverse species with similar clades. Average loss of 13.5% in phylogenetic diversity reported across five continents.
The VIIRS instrument aboard NASA-NOAA's Suomi NPP satellite captured a true-color image of Tropical Cyclone Marcus on March 18, 2018. The storm brought hurricane-force wind gusts to Darwin, Australia, and was moving west at 16 mph per hour.
A Canadian study found that mothers living in households with food insecurity are less likely to breastfeed their infants exclusively for six months. The research, published in the Canadian Medical Association Journal, highlights the negative impact of food insecurity on breastfeeding duration.
Researchers uncover evolutionary origin of vertebrate limbs by analyzing genetic elements first used to develop dorsal fins in ancient fish. The findings suggest that these elements were later redeployed to produce paired appendages, like arms and legs.
Researchers developed a point-of-care device that simultaneously probes patient hemodynamics, chemical constitution, and anatomy to diagnose thyroid nodules. The device uses near-infrared time-resolve spectroscopy and diffuse correlation spectroscopy to collect tissue data, promising improved accuracy and reduced costs.
A new study by NYU Langone Health reveals that patients from lower-income areas have a significantly reduced chance of surviving anal cancer. The research, led by Dr. Daniel Becker, found a strong association between median household income and overall survival rates.
Scientists have developed tiny, implantable sensors that can detect various body chemistries without triggering an immune response. The devices are being marketed in Europe and are expected to receive US approval, with potential applications including monitoring oxygen levels in patients with peripheral artery disease.
Researchers create first kagome metal, an electrically conducting crystal with individual atoms arranged in a repeating triangular pattern. The material exhibits strange, quantum-like behaviors in passing electrons, including bending and creation of nearly massless particles.
Researchers have identified two new biomarkers, a trio of RNA molecules, to help determine the severity of neuroblastoma in children. This discovery has immediate significance for disease prognosis and will eventually contribute to more effective treatments.
Researchers at the Salk Institute found that nematode worms exhibit a rudimentary fear-like response when exposed to chemicals from their predator, which has parallels to human anxiety. This discovery may lead to refined prescriptions for current anti-anxiety drugs and enable new treatments for PTSD and panic disorder.
A recent study from the University of Waterloo found that Muslims are the least liked group in Canada, with higher rates of discrimination than most other demographic groups. Residents of Quebec and those with conservative views hold more negative feelings towards Muslims.
Researchers developed two nanofiber dressings that use naturally-occurring proteins to promote healing and regrow tissue. The dressings, inspired by fetal tissue and soy-based molecules, showed significant improvements in wound healing, including 84% tissue restoration within 20 days.
Researchers developed a monoclonal antibody targeting BamA in Gram-negative bacteria, inhibiting its function and compromising outer membrane integrity. The treatment shows promise for developing therapeutics against these bacteria.
Scientists found that a small daily dose of Viagra significantly reduces colorectal cancer risk in genetically predisposed animal models. The drug works by increasing levels of cyclic GMP, which suppresses excessive cell proliferation and promotes normal cell differentiation.
The loss of seagrass meadows at Shark Bay has released up to nine million metric tons of carbon dioxide, equivalent to the annual CO2 output of 800,000 homes. Seagrass ecosystems are crucial for storing carbon, and climate change is compromising their permanence.
Researchers collected three tumor samples from a patient with salivary gland cancer, revealing a significant increase in cancer stem cells and aggressive mutations over time. This study demonstrates how tumors can adapt and overcome therapies, leading to relapse and treatment resistance.
Researchers have discovered biochemical mechanisms that help female beetles produce the aggregation pheromone trans-verbenol in response to juvenile hormone III. This finding may improve forecasting of bark beetle outbreaks by understanding how these insects communicate and colonize pine trees.
Scientists have discovered a human antibody, CIS43, that protects against malaria better than any previous antibody, and identified a unique binding site on the malaria parasite's surface protein. This could lead to new pathways for malaria prevention, potentially offering an effective vaccine or direct infusion therapy.
Researchers calculate glacier melting under different climate scenarios, finding that up to 36% of ice could melt without further emissions. Compliance with 1.5°C global warming goal makes little difference in the next 100 years.
Researchers discovered that asbestos exposure sends exosomes to distant cells, causing genetic changes and potentially leading to cancer or diseases. The findings suggest a new mechanism by which asbestos triggers deadly cancers.
A new study suggests that taxing sugar-sweetened beverages could increase stigma for already-marginalized populations, including those of low socioeconomic status and Aboriginal peoples. The authors argue that taxation policies must consider the potential unintended consequences on these groups.
A new study published in Nature Ecology and Evolution suggests that herring larvae may survive better in a future acidified ocean due to an altered food supply. This unexpected result could have implications for the long-term survival of fish populations.
A European project is developing circular economy solutions using agricultural and fisheries waste to improve soil quality and reduce CO2 emissions. The Horti-BlueC project replaces non-renewable resources with local waste, producing bio-energy, biochar, and biodegradable materials.
The study found that nearly half of the wives reported that their partner's health problem affected their own health, with many feeling increasingly socially isolated. The women also expressed concerns about the role change in their relationship as their husbands became less able to fulfill their usual roles.
The Canadian Medical Association Journal (CMAJ) is championing the health of vulnerable populations with a special focus. The journal aims to shine a light on vulnerability in healthcare and empower those who are most affected.
Severe TBI in children increases risk for attention-deficit/hyperactivity disorder (ADHD) up to 7 years after injury. A study of 187 children with TBI compared to orthopedic injury found 25.7% developed secondary ADHD, highlighting the need for post-injury monitoring.
A new study by UTSA researchers presents a method to stop cyber attacks on GPS-enabled devices, including electrical grids and driverless cars. The algorithm can recognize false GPS signals and counter an attack in real-time, making it crucial for securing GPS signals used in various technologies.
A team of EMBL scientists has developed a comprehensive 'cookbook' for growing and studying 96 diverse gut bacterial strains. The research reveals unexpected nutritional preferences and growth characteristics of these bacteria, providing valuable insights into the human gut microbiome.
A new test developed by chemists can screen for synthetic opioids and cannabinoids in just under five minutes, helping medical staff identify the cause of an overdose. The device uses a small cartridge to extract and analyze drugs from blood samples, providing a potential solution to the growing crisis of opioid overdoses.
Dr. Helen Hobbs has made a groundbreaking discovery linking a gene mutation (PCSK9) to lower levels of LDL, or 'bad cholesterol', improving treatment of high cholesterol. Her research led to the development of an FDA-approved therapy within 10 years.
A study of 302 postmenopausal women found that prescribed vaginal estradiol hormone tablets and over-the-counter vaginal moisturizer didn't improve symptom relief or sexual function compared to a placebo. The researchers conclude that a better understanding of the underlying mechanism is needed to develop more effective treatments.
Researchers have identified a wax-like hydrocarbon called heneicosane as a royal recognition pheromone in termites, enabling workers to recognize and care for queens and kings. This discovery could upend current understanding of insect social behavior and evolution, suggesting that CHCs evolved as royal pheromones 150 million years ago.
A study by University of North Carolina at Chapel Hill found that primary care physicians feel underequipped to address prenatal oral health, with only 45% feeling prepared. The authors suggest improving training and education on oral health for primary care physicians.
Researchers have uncovered previously unknown reservoirs of trans-verbenol in juvenile mountain pine beetles, which could aid in predicting outbreaks. The study found that female beetles accumulate and store the pheromone during their larval and pupal stages.
A new study found that children born to mothers with a larger waist size (80 cm or more) before pregnancy are at a 65% higher risk of developing autism. The research suggests inflammation may play a key role in this link.
Researchers found that participants on the 5:2 diet cleared triglyceride from a meal more efficiently than those on daily calorie restriction, reducing an important risk factor for cardiovascular disease. The study also showed a greater reduction in systolic blood pressure in participants on the 5:2 diet.
Researchers generate self-organizing liquids into patterns, enabling design of emulsions resembling Russian nesting dolls. The method offers potential new pathways for developing more sophisticated pharmaceuticals and other consumer products.
Researchers have made groundbreaking discoveries regarding the onset of cholera, paving the way for a fast-acting antidote. The study shows that mice without a specific receptor can still get diarrhea after consuming cholera toxin, offering new possibilities for producing a drinkable antidote.
Researchers discovered micron-scale particles linked to a magnetic field can self-assemble into swimming motion, replicating human breaststroke. The ability can be controlled with an eccentric magnetic field, allowing for potential use as drug-delivery vehicles or micro-robots.
Research published in BMC Public Health found an association between increased social media time and reduced wellbeing in later adolescence among girls. However, the study did not find a similar association for boys.
A large study found that Métis adults have higher rates of lung, liver, and breast cancers, as well as poorer prostate cancer survival rates. The study also identified lower incidence rates for melanoma and leukemia in Métis adults compared to non-Aboriginal people.
Scientists have identified genetic patterns in Haemophilus influenzae that make certain strains more dangerous than others. This discovery may lead to the development of new treatments and vaccines for Chronic Obstructive Pulmonary Disease (COPD) patients.
A human brain imaging study found that LSD reduces activity in areas important for establishing one's sense of self, blurring the line between self and other. The serotonin receptor system appears to be a target for treating social impairments in disorders such as depression and schizophrenia.