PRRT is an approved treatment modality for gastroenteropancreatic neuroendocrine tumours, particularly in midgut NETs. In Australia, PRRT is used more widely than previously thought, despite limited Phase III trial data for lung NETs.
A new report provides a path forward for research on the complex links between climate change and violent conflict. The study suggests prioritizing deepening insight into climate-conflict linkages, integrating research designs, and evaluating interventions to manage climate-conflict risks.
TARA's in vitro human cardiac models replicate drug responses similar to those observed in humans, supporting their use as a robust platform for new medicines evaluation. The models' ability to reproduce diverse mechanisms of action showcases their applicability for cardiac drug discovery and development.
A new bird checklist from Jicarón and Jicarita islands in Coiba National Park reveals 23 previously unrecorded species, including 10 endemic subspecies and 29 migratory birds. The islands' unique terrain supports a variety of bird species, with some rare migrants recorded.
Researchers at GIST developed an active photonic wireless system to power medical implants, eliminating the need for invasive battery replacements. The system uses photons to recharge devices in live tissues, enabling long-term use and accelerating emerging implant technologies.
Researchers analyzed data from 2000-15 and found that electing women to local, state, and federal levels of decision making reduces child mortality. Higher representation leads to reductions in child mortality rates, with a 0.038 percentage point decrease for federal Chamber of Deputies and .038 percentage points at the state level.
A recent study confirms theories developed by physicists over the last two centuries, showing the Earth's atmosphere vibrates like a bell. The study analyzed atmospheric pressure data for 38 years, revealing dozens of predicted wave modes, matching theory well.
Recent trials of COVID-19 treatments often use time to a positive outcome as a key endpoint, but this may not be suitable when death is a competing risk. The authors propose alternative methods for interpreting treatment effects in COVID-19 studies.
Scientists from Osaka University have reduced X-ray free-electron laser beam diameter to 6 nanometers, enabling precise imaging of single virus particles and ultrafast chemical processes. This advancement improves the accuracy of measurements closer to the atomic level than previously possible.
A new study from the University of Cambridge suggests that individuals with less active jobs, typically office-based desk jobs, performed better at cognitive tests and were at lower risk of poor cognition. Those in manual work had almost three times increased risk of poor cognition than those with an inactive job.
A study by Baylor College of Medicine researchers integrates whole-exome sequencing with untargeted metabolomics to identify genetic causes of undiagnosed conditions. The integrated analysis informed 44% of cases, reclassifying variants as likely benign or disease-causing and confirming clinical diagnoses in 21 cases.
A study by University of Illinois expert Carlos Torelli finds that moral appeal can persuade people to donate to foreign charities, even if resources could be used closer to home. Donors prioritize feelings of fulfillment over local impact.
The study reveals that Burkholderia pseudomallei infection sets off a series of events that provoke the host's immune system, causing infected cells to self-destruct. The researchers found that abnormal cell fusion stimulates the type 1 interferon signaling pathway, leading to autophagy and cell death.
Recent record-high water levels have caused significant impacts on Great Lakes state parks, including shoreline erosion and flooding. The study found that 50% of the surveyed parks were affected, with total damage costs ranging from $50,000 to extensive repairs.
New research from Anglia Ruskin University found that women and older adults are more likely to meet exercise targets, whereas men and younger adults were less active. The study suggests that the public's increased free time during lockdown led to higher levels of physical activity.
Researchers identified eight new acetyltransferases in plants, which are doubly catalytically active and play a role in photosynthesis. The study reveals an entirely new complexity within the enzyme machinery, suggesting other enzymes with similar dual activities exist in eukaryotic cells.
A new analysis of Dilophosaurus fossils reveals the largest land animal of its time had much in common with modern birds, including powerful muscles and air-filled bones. The study also sheds light on how Dilophosaurus evolved and its place in the family tree.
Parents who perceive that early childhood education centers communicate well with them are more likely to engage in educational activities, such as reading and singing, both at the center and at home. The quality of these activities is a stronger predictor of school readiness than their quantity.
The HPTN 083 clinical trial showed that a long-acting cabotegravir injection was superior to daily oral tenofovir/emtricitabine for HIV prevention among cisgender men and transgender women. The study found a 66% reduction in incident HIV infections in participants given cabotegravir compared to TDF/FTC.
A common finding across three continents reveals that atmospheric turbulence enhances new particle formation (NPF), a key process for haze development. NPF growth rates are faster under stronger turbulence conditions, while instability parameters prolong event durations.
A new study suggests that vehicle electrification has substantial potential to reduce both climate change and air pollution damages. However, a clean electricity grid is crucial for a sustainable transportation future.
The BIO Integration Journal bridges the gap between laboratory, clinic, and biotechnology industries, offering a cross-disciplinary platform for biomedical research advances. Featured papers emphasize interdisciplinary integration in COVID-19 research and immunotherapy strategies.
A simple measuring tape could identify which Zika virus-exposed children develop neurological abnormalities. Head circumference growth trajectory is also key, with 10.5% going on to develop microcephaly in months after birth.
A new study published in Nature Communications suggests that climate change will intensify winds steering hurricanes north over Texas, increasing the likelihood of fast-moving storms. The research found a 50% rise in the chances of fast-moving hurricanes compared to slow-movers like Harvey.
Researchers designed an air filter that can trap and kill the coronavirus and other pathogens, with a 99.8% kill rate in a single pass. The filter uses nickel foam heated to 392 degrees Fahrenheit, eliminating the need for external heating sources and minimizing strain on HVAC systems.
Researchers are exploring how amyloid plaques degrade the brain's vascular system by impairing astrocytes, leading to a weakening of the blood-brain barrier. The study aims to pinpoint genes and proteins in astrocytes that contribute to Alzheimer's disease progression.
Researchers successfully deliver gene therapy using nanoparticles to inhibit abnormal blood vessel growth in rats and mice eyes, providing evidence for treating wet age-related macular degeneration and inherited retinal diseases.
A new study reveals that seagrass loss in Australia has led to a 2% increase in annual carbon dioxide emissions, equivalent to 5 million cars per year. The research highlights the vital role seagrass meadows play in mitigating climate change and urges preservation and restoration of these ecosystems.
A new study from Penn Medicine found that abnormal function of sensory neurons outside the brain contributes to autistic social behaviors. Peripheral sensory systems can serve as more accessible therapeutic targets for treating ASD-related symptoms.
A new study published in Nature Astronomy sheds light on the origin of carbon in the Milky Way, revealing that dying stars play a crucial role in its synthesis. The research team found that low-mass stars shed more massive remnants than previously thought, breaking a linear trend in star formation and planetary evolution.
A new method uses phased ultrasound to levitate and manipulate objects in living bodies, including solid glass spheres. Researchers believe this technology could be used to guide the clearance of kidney stones or manipulate an ingestible camera.
Researchers developed a liquid crystal integrated metalens that can achieve both achromatic and chromatic focusing with a single device. The design overcomes the challenge of chromatic aberration, allowing for improved resolution in full-color and hyperspectral imaging.
Researchers developed a deep learning method that enhances global climate models' ability to predict wind velocity and solar irradiance data, leading to more accurate renewable energy prospects. The approach results in high-resolution modeling under various climate scenarios.
A study analyzed 664 news articles about suicide posted on a social network between 2018 and 2019. The findings suggest that adherence to suicide reporting guidelines may benefit individual health as well as reader engagement, with US-based publications being less likely to adhere to the guidelines.
Researchers used ChIA-PET to map associations between proteins and DNA in prostate cancer cells, discovering hubs of interacting enhancers that regulate gene expression. These findings may lead to novel treatments for the most common type of prostate cancer.
A new study found that genomic traits of the hive are strongly associated with how fiercely its soldiers attack. The research suggests that the genetic makeup of the society, not individual bee genetics, plays a key role in aggression.
Brown bears increasingly live among human settlements due to habitat loss, leading to conflict and high mortality rates. The study found that connected wilderness areas and nocturnal behaviors are crucial for coexistence between humans and bears.
A study by researchers from the University of Bristol has identified the ancestral origin of tequila bats in Mexico, revealing distinct migratory patterns and breeding habits. The findings support the need for targeted conservation management strategies to protect this Near Threatened species.
A team of researchers discovered a new class of pipeline drugs to relieve pain and reduce fever, excluding hepatotoxicity and opioid addiction. The findings have significant implications for acute and chronic pain management, particularly in the COVID-19 pandemic.
Ornithologists at the University of Utah found that community science bird data shows different trends in bird populations than professional surveys, especially in developing countries. The researchers hope to encourage more conscientious recording and connection between birders and professionals to fill data gaps.
Researchers from CNRS and University of Poitiers have explained the 'dead water' phenomenon in ships, where waves create drag, slowing down or stopping vessels. The study reveals waves act like an undulating conveyor belt, causing speed oscillations in trapped boats.
A team of scientists investigated the structure and function of a key protein called IsiA in cyanobacteria. They found that IsiA acts as an energy harvester and donor, transferring captured energy to the trimeric core of PSI. The study provides important insights into photosynthetic energy transfer mechanisms.
Researchers at NYU Abu Dhabi investigate how cellular crowding affects the speed of motor proteins in groups versus singularly, with findings that crowding impacts group movement but not individual motors. The study uses optical tweezers to simulate crowded environments, revealing the balance between motor function and cell survival.
A new platform technology can assess water safety and quality with just a single drop and minutes. The platform tests for 17 different contaminants, including toxic metals, pharmaceuticals, and cosmetics, providing fast and easy results.
Researchers found that climate change positively impacts yellow-bellied marmot survival during short, wet summers and negatively affects it during harsh winters. This study suggests that certain species may benefit in one season while facing unfavorable conditions in another due to climate change.
Lobachevsky University scientists have developed new ways to modify the structure of aluminium alloys, improving their performance. They used induction casting in vacuum and plastic deformation technologies to create homogeneous highly plastic structures that maintain high strength, thermal resistance, and electrical conductivity.
A team of scientists at New York University has found that tiny eye movements can be used as an index of humans' ability to anticipate relevant information in the environment. The study reveals a connection between eye movements and the sense of touch, with micro-saccades hindering tactile discrimination and suppressing them enhancing it.
Researchers have successfully investigated the basic mechanisms of molecular factories in bacteria, revealing insights into the production of complex structures like polyketides. This discovery inspires targeted manipulation of biochemical processes, leading to potential improvements in antibiotics and other drugs.
A new review of lizard data reveals that up to 2.75% of all lizards may have two or more tails, with potential ecological impacts on individual fitness and population dynamics.
A recent study suggests that coronary calcium scoring can guide personalized preventive care for individuals with moderate cardiovascular risk. The test identifies calcium deposits in the arteries, indicating atherosclerosis and high heart attack and stroke risk.
A study of prospective teachers found that they are more likely to interpret the facial expressions of Black boys and girls as being angry, even when they are not. The authors suggest that this 'racialized anger bias' could have significant adverse effects on children in classrooms.
Researchers studied SARS-CoV-2 antibodies in 11,066 patients, finding they associate with clinical severity and provide valuable diagnostic support. Obesity is associated with worse COVID-19 outcomes in NYC cohort of 1,687 persons hospitalized with confirmed cases.
Researchers developed a graphene-based ultrathin lens that can be electrically tuned to adjust focusing and eliminate chromatic aberration. The device features high transmittance, high resolution, and multifunctional capabilities for various display applications.
Researchers developed a new silicon chip with no moving parts that improves lidar system resolution and scanning speed, enabling applications in self-driving cars and smartphones. The breakthrough could lead to cheaper, smaller, and more complex lidar systems.
Research found that owner behavior, rather than internal principles like the principle of least effort, affects the effort and accuracy of dogs' showing. Owners who encouraged their dog to show where a toy was hidden increased effort but decreased accuracy.
A new USC study has created a hate speech classifier that is more context-sensitive, reducing errors that amplify racial bias. The algorithm considers context and specific features of hate speech to improve accuracy.
A Rutgers study reveals that sewer pipe walls harbor biofilms containing antibiotic-resistant bacteria, which can withstand standard disinfection methods. Cleaning with bleach can reduce biofilm density but not remove them entirely, posing health risks to wastewater treatment workers and the public.
In cluttered environments, bats use lowest broadcast frequencies to detect nearby objects and ignore distant echoes. By ignoring long-delay echoes elicited by initial broadcasts, bats can accurately match echoes with corresponding broadcasts.
A new study published in eNeuro found that motherhood takes over the brain's decision-making regions to prioritize caring for offspring. The infralimbic cortex directs mothers to choose their pups over drugs, promoting maternal behavior.
Children living in homes with private wells were more likely to have elevated blood lead levels than those with city water. Researchers found that African American neighborhoods lacking access to municipal water service faced compounded risks.