A major new report suggests that children's chronic pain is often ignored or undertreated, with up to 10% of young people experiencing disabling conditions. The Lancet Child and Adolescent Health Commission recommends four key goals: making childhood pain matter, understanding it, making it visible, and managing it effectively.
The NIH has launched the ACTIV-5 Big Effect Trial to determine whether certain approved therapies or investigational drugs show promise against COVID-19. The study will enroll adult volunteers hospitalized with COVID-19 at up to 40 US sites and test three investigational treatments against a placebo.
A study published in Circulation journal reveals that a specific population of cardiac fibroblasts, called Reparative Cardiac Fibroblasts (RCF), play a crucial role in repairing damaged heart tissue after a myocardial infarction. The RCF cells produce a protein called CTHRC1, which is essential for the healing process.
A new study found that women in states with less restrictive reproductive rights policies are less likely to give birth to low-birth weight babies. Specifically, US-born Black women have a 7% lower risk of low-birth weight compared to those in more restrictive states.
Researchers at ETH Zurich have developed a novel approach to frequency doubling in nonlinear crystals, utilizing disordered nanocrystals to achieve efficient light conversion. The method, which combines two seemingly irreconcilable approaches, enables wide-range frequency tuning and minimizes material usage.
Children with multiple neurodevelopmental conditions experience greater school absenteeism, poorer exam attainment, and increased unemployment. The study highlights the need for interventions to address the unique challenges faced by these children, who often fall through the cracks due to a lack of recognition of their complex needs.
Researchers have developed core-sheath polymer fibers that combine strength with bioactivity, enabling various biomedical applications. The fibers can be tailored to specific needs by carefully selecting inner and outer layer materials, and can even include antiviral agents or drugs.
Research reveals that 14 out of 18 species observed suffered damage from pot fishing, including indicators of general health in the marine environment. The study highlights the need for authorities and fishing communities to balance ecology with social and economic considerations.
A 10-year study from Flinders University has found that removing only a portion of the tonsil can significantly reduce pain and bleeding after surgery. Children who underwent this partial removal procedure returned to normal activities in under half the time compared to those who had their entire tonsil removed.
A study has overcome a key hurdle to the use of nanorobots powered by lipases, enzymes that play essential roles in digestion. By modulating motor speeds, researchers have broadened the potential biomedical and environmental applications of these devices.
Researchers quantify total cell inventories under in situ conditions using non-biased visualization methods. The study reveals that about 1 percent of microbial cells in the ocean surface microlayer inhabit plastic debris globally, disrupting native flora and representing a regime shift for these habitats.
Researchers found that moles stop growing due to normal cell-to-cell communication, not stress from cancer genes. This discovery could lead to new treatments for preventing skin cancer by exploiting existing mechanisms controlling cell growth.
Research finds that increasing feelings of ownership towards a public good enhances stewardship behavior, causing individuals to take direct action to care for the setting. Participants who felt a sense of ownership were more likely to pick up trash or donate money to park maintenance efforts.
A new study published in PLOS Medicine found that restricting television advertising for food and beverages high in fat, sugar, and salt could lead to a significant reduction in childhood obesity rates. The research suggests that limiting ads between 5:30am and 9pm could result in a 4.6% decrease in obese children, equivalent to 40,000...
Researchers from Russia and Switzerland successfully replicated the self-cleaning anti-reflective coating found in fruit flies' eyes, which can be applied in various fields such as textiles, medical implants, and contact lenses. The new nanocoating boasts antimicrobial, anti-reflective, and self-cleaning properties.
A study of twins found that one in four adults changed their alcohol use almost immediately after stay-at-home orders were issued, with 14% reporting higher levels of stress and anxiety. The study suggests a link between decreased drinking and increased mental health issues, highlighting the need for better support.
Tropical Storm Delta made landfall in Louisiana, weakening to a tropical depression with maximum sustained winds near 25 mph. The NASA Terra satellite captured visible imagery of the storm's organization, which was compiled into an animation showing its landfall and movement.
A new UNIGE study models 100 feasible scenarios to achieve Central European electricity sector targets by 2035. The research highlights trade-offs between cost-efficiency, renewable electricity, and regional equality, suggesting a compromise is possible to share costs and benefits evenly across regions.
A partnership between Sandia National Laboratories and BioBright LLC aims to improve synthetic biology equipment security. The team is developing countermeasures to risks, protecting America's bioeconomy and digital infrastructure from potential data theft or targeted attacks.
A new study led by Massachusetts General Hospital found that frequent phone counseling significantly improves quit rates among cancer patients who smoke. The intensive program resulted in a 34.5% abstinence rate, compared to 21.5% for those receiving less frequent counseling.
The Great Barrier Reef has lost half its corals in the past three decades, with small, medium, and large coral populations declining by more than 50 percent. This decline is driven by climate change, which is causing record-breaking temperatures to trigger mass bleaching events.
A new silk-based wound dressing infused with nanodiamonds can detect early signs of infection, promote healing and reduce infection from certain bacteria. The technology offers a non-invasive solution to traditional wound management challenges.
Researchers studied COVID-19 patients' immune systems, discovering potent biomarkers and patterns in T-cell and B-cell receptor proteins. The study aims to develop treatments inspired by the immune system, with potential clinical applications including prognostic tests and antibody therapies.
Researchers at the University of Central Florida have developed a technology that enables large machines to breathe in and out cooling blasts of water, keeping their systems from overheating. The system uses pulsed water-jet cooling and has been found to be effective in cooling hot electronic devices and surfaces.
Researchers studied antibody production in nearly 6,000 people and found high-quality antibodies still being produced five to seven months after SARS-CoV-2 infection. Immunity is stable for at least five months, and may last much longer.
Research by Arizona State University professor Andrew Smith finds that American pikas are adapting well to warm temperatures, with healthy populations across their range. The species is able to tolerate a broader set of habitat conditions than previously understood, coping with heat by retreating to underground habitats.
A new study from the University of Utah reveals that mixed landscapes, comprising both trees and grass, are the most effective way to cool temperatures in the Salt Lake Valley. Lawns actually outperform trees in reducing daytime and nighttime temperatures by acting as a swamp cooler, while more open areas allow for better heat escape.
A new study published in Psychological Science reveals that empathy is a key factor in preventing the spread of COVID-19. The research shows that individuals with higher empathy levels are more likely to keep their distance and wear face masks to protect vulnerable populations.
The genus Iris, comprising over 300 species, has a poor fossil record, but researchers created a phylogeny to study evolutionary divergence. They found the last common ancestor of irises probably had purple flowers with a crest and spot on falls, pollinated by insects for nectar.
A new AI-based model can help public officials and team owners make informed decisions about in-person attendance by predicting COVID-19 trends. The tool provides insights into doubling times and case increases in counties with NFL/NCAA stadiums, aiding in risk assessment and safety guidance.
Researchers discovered that Pluto's mountains are snowcapped with frozen methane, formed at high altitudes where the atmosphere is rich in methane. This finding explains why Pluto's glaciers have craggy ridges unlike Earth's flat ones.
A team of scientists developed a mathematical model simulating the disruption of heat distribution by strong magnetic fields, creating hotter and cooler regions that emit x-rays of differing intensity. The findings help explain the observed changes in brightness of magnetars studied over several decades.
A new study shows early-terminated rye can effectively suppress weeds in edamame without harming the crop, increasing yield and reducing contamination. However, other crops like lima bean may not benefit from this approach due to their nitrogen-fixing limitations.
A new study shows that COVID-19 can cause neurological injuries in approximately one in seven infected patients. These injuries range from temporary confusion due to low oxygen levels to stroke and seizures in the most serious cases, significantly raising a patient's risk of dying while still in hospital.
The NCI-MATCH trial, the largest precision medicine cancer trial to date, has made significant contributions to the use of tumor gene testing in selecting treatment for patients. The study found that nearly 40% of patients have matching tumor gene defects for targeted treatments.
Researchers establish relationship between soil nitrogen at different growth stages and corn yield, finding a tradeoff between productivity and environmental impact. Soil nitrogen explains majority of grain yield variation, with optimal levels resulting in 22% yield increase.
Researchers at North Carolina State University developed a machine-learning model to predict how long individual visitors will engage with exhibits. The model achieved accurate predictions using only facial expressions and posture data, with better performance when visitors interacted with the exhibit for longer periods.
A study by the University of Jena found that a toxic substance from Staphylococcus aureus stimulates immune cells to produce anti-inflammatory messenger substances, reducing inflammation and promoting tissue healing. The researchers also demonstrated that these substances promote tissue regeneration in an animal model.
Scientists created a 3D structural model of the BAF complex, which modifies DNA architecture and is frequently mutated in cancer. The new model provides critical insights into how mutations disrupt gene regulation and tumor growth.
A team of physicists successfully transported light stored in a cloud of ultra-cold rubidium-87 atoms over 1.2 millimeters using an optical conveyor belt. The controlled transport process has minimal impact on the stored light's properties, enabling potential applications in quantum communication and computing.
A new deep learning model inspired by tiny animals has shown decisive advantages over previous models in tasks such as autonomous driving. The model achieves better performance with fewer neurons and is more interpretable than complex 'black box' systems.
The LCR robot can remove full-range aircraft coatings layer-by-layer, shortening processing time by up to 80% and reducing cost-per aircraft. It is compatible with all types of aircraft and helicopters, and can also be used for off-airframe parts.
A recent NIH-funded study found that microstructural brain differences in the nucleus accumbens predict increases in indicators of obesity in children. The Adolescent Brain Cognitive Development Study reveals a link between diet-related inflammation and unhealthy eating behaviors.
Scientists developed compact solid-state pulse generators that can produce electrical pulses of less than one billionth of a second in duration and up to 50 billion watts in power. This breakthrough sets the groundwork for new applications in fields such as high-power microwave electronics and X-ray imaging devices.
Astronomers find galaxy Dragonfly 44 has normal amount of dark matter, contrary to earlier claims. The team discovered only 20 globular clusters, reducing the amount of dark matter, and confirming that the galaxy is not unique or anomalous.
MIT researchers developed a new technique to recapture lost information from single-cell RNA-sequencing, enabling the extraction of 10 times more data per cell. This breakthrough helps identify subtle differences between healthy and dysfunctional cells, with potential applications in disease diagnosis and treatment.
The study used Mossbauer spectroscopy to analyze iron-containing catalysts and determine their phase composition before and after thermal steam exposure. The results indicate that maghemite is reduced to magnetite when the iron oxides react with water vapor during catalytic aquathermolysis of crude oil.
A new study published in Eating and Weight Disorders found a strong correlation between eating disorders and body dysmorphia, affecting 76% of participants. The research suggests that healthcare professionals should screen individuals with body dysmorphia for eating disorders regularly.
Researchers at the University of California, Irvine discovered that skin cells communicate with each other through protein signals to stop growing and prevent cancer. This finding could lead to new treatment options and potentially prevent melanomas from developing in the first place.
A Monash University study warns of devastating impacts of climate change on wildfire seasons, with fuel, oxygen, and ignition source conditions fueling the crisis. Immediate action is needed to limit greenhouse gas emissions and avoid substantial increases in wildfire exposure by the end of the century.
Researchers from MIPT have developed a prototype detector of high-energy particles capable of picking up protons and electrons with energies between 10-100 MeV. The device improves radiation protection for astronauts and advances our understanding of solar flares.
Researchers found that compressing cells can trigger cell growth and division, increasing stem-cell state. Squeezing intestinal cells activates specific proteins, leading to larger organoids with more stem cells on their surface.
Researchers at Monash University discovered that metformin, a diabetes drug, removes damaged proteins and restores swimming ability in zebrafish with myofibrillar myopathies. The treatment shows promise for children suffering from this rare genetic disease.
A 45-year-old man with asthma experienced sudden permanent hearing loss in one ear after being treated for COVID-19, highlighting a possible new side effect. Prompt steroid treatment can reverse the condition.
The study finds that high miR-708 expression is associated with survival rates in lung squamous cell carcinoma patients. Additionally, miR-708 decreases proliferation, survival, and migration of lung cancer cells by inhibiting PGE2 signaling.
A new study summarizes over 30 years of clinical experience in treating glutaric acidemia type 1 (GA1), a rare and devastating metabolic disorder. The clinic's therapies have reduced brain injury risk by 83%, improving treatment outcomes for individuals with GA1.
Gryfn, a Purdue University-affiliated agbioscience startup, is growing its space and expanding into new markets with its multisensor drone data collection technology. The company has added team members, evaluated new technologies, and is actively recruiting a research scientist to empower the future of agriculture research.
Researchers analyze how our minds plan resource use to reduce excessive energy consumption and carbon emissions. They propose concrete strategies to fine-tune policy instruments and promote sustainable behavior, taking into account cognitive mechanisms such as spillover effects, rebound effects, and mental accounting labels.
Researchers found a warming trend in the deep sea, with temperature fluctuations detectable at depths of up to 4,757 meters. The increase in temperatures is consistent with global climate change, but more research is needed to understand its causes.
Researchers discovered that immune system T cells can home-in on tumor cells independently of intermediary immune cells and release chemical signals that attract more T cells. This 'swarming' behavior could help develop new cancer therapies targeting solid tumors, currently less responsive to immunotherapies.