Researchers at Università Cattolica and Roma Tre University discovered phosphatase B55 as a master regulator of mitochondrial degradation and biogenesis. By modulating its activity, they found it can reduce Parkinson's symptoms in animal models.
A large-scale study uncovered a strong connection between osteoporosis and rotator cuff tears, finding that individuals with osteoporosis are 1.56 times more likely to suffer an RCT. The study also identified common genetic variants influencing both conditions, suggesting a possible biological explanation for the link.
Death rates from unintentional injury related to drug use increased by nearly 60% from 2018 to 2023. Middle-aged adults, particularly those aged 35-44, were found to be at higher risk of death from drug-induced accidental injuries.
Human GII.4 noroviruses have evolved a uniquely potent entry mechanism with clear strain-specific differences, according to researchers at Baylor College of Medicine. The study reveals that clustering strains, such as GII.4 Sydney, cause more membrane wounding and replication in enteroids compared to non-clustering strains.
Researchers have identified a retrograde trafficking pathway in Arabidopsis thaliana that retrieves proteins from vacuoles to endosomes. This plant-specific innovation plays a crucial role in seed germination and energy storage.
A team of researchers from Japan has developed a novel approach to convert waste heat into electricity with higher efficiency than traditional methods, leveraging non-thermal Tomonaga-Luttinger liquid. This breakthrough could pave the way for more sustainable low-power electronics and quantum computing.
Rural patients face significantly longer emergency medical services call times due to limited access to specialized trauma centers. High-acuity activations are more common in rural areas, resulting in extended transport times.
A new spinel-type sulfide semiconductor, (Zn,Mg)Sc2S4, has been developed by researchers at Science Tokyo. The material can be chemically tuned to switch between n-type and p-type conduction, making it suitable for pn homojunction devices in next-generation LEDs and solar cells.
Scientists recreated a traditional Balkan yogurt recipe using ants, finding that the insects' natural chemicals and microbes can kickstart the fermentation process. The researchers tested live, frozen, and dehydrated ant products, concluding that only live ants are suitable for yogurt making.
Researchers found that small increases in lung scarring over one year signal higher risk of worsening disease, mortality, and steeper declines in lung function. These changes were strongest in patients with less severe disease at baseline, highlighting the potential for earlier intervention to alter disease course.
Researchers identify abnormal sugar modifications linked to depressive behaviors, offering potential diagnostic and therapeutic targets. Chronic stress disrupts sugar chains in the prefrontal cortex, triggering depression.
A six-year analysis of coroner records from Ohio reveals that over 40% of drivers who died in fatal crashes tested positive for active THC in their blood, with average levels exceeding most state impairment limits. The study found no change in THC positivity before or after the legalization of recreational cannabis.
Research suggests that American lobsters are more resilient to ocean acidification than previously thought, but they are highly sensitive to heat stress. The study found that warmer water led to faster embryo development, but smaller larvae with decreased survival prospects in the wild.
Research from Umeå University reveals that natural barriers shape the flow of water and hinder plant dispersal in rivers shaped by the last Ice Age. The study found no clear correlations between drainage area and channel width, or consistent increase in plant species diversity downstream.
A new study calls for standardized, transparent, and reproducible methods to evaluate frailty in preclinical aging studies. The researchers analyzed 18 rodent studies and found substantial variation in how frailty is defined and measured.
A novel molecular coating enhances the consistency and precision of quantum light sources, increasing their spectral purity and controlling photon energy. The coating protects single-photon emitters from atmospheric contaminants, enabling reliable quantum devices for secure communications and ultra-precise sensors.
The Society for Maternal-Fetal Medicine (SMFM) has released new guidance on diagnosing and managing heart failure during pregnancy and postpartum. The guidance highlights the importance of preconception counseling, assembling multidisciplinary care teams, and referring patients to centers with expertise.
A team of researchers at Penn State developed a framework to use existing streetlights as EV chargers, resulting in cheaper installation costs and faster charging speeds. The study found that this approach offers an equitable and sustainable solution for expanding charging infrastructure, particularly in urban areas.
A new study from Karolinska Institutet reveals that postural orthostatic tachycardia syndrome (POTS) affects nearly a third of patients with severe long COVID, with middle-aged women being the most common demographic. Researchers emphasize that POTS can be detected with simple tests and treated to alleviate symptoms.
A new study found that nearly half of UK households underestimate how much plastic they throw away each week, with online shoppers being the most unconscious consumers. The research calls for supermarkets to change infrastructure and systems to promote reuse and refill schemes.
A new multi-institutional study published in Health Science Reports found that adults with newly diagnosed low back pain who received spinal manipulative therapy administered by a chiropractor were significantly less likely to be diagnosed with opioid use disorder over a two-year follow-up compared to those prescribed ibuprofen. The st...
Women undergoing mastectomy may experience emotional and physical challenges, including worse psychosocial outcomes and a lack of standardized approach to assess quality of life. Researchers emphasize the importance of developing a validated screening tool to prepare women for surgery.
A study by the University of Helsinki finds that mothers' difficulties in bonding with their babies at eight months are associated with increased sleep problems. These problems persist up to 24 months, with maternal depressive symptoms exacerbating the issue.
Researchers used a digital twin model to predict soil fertility and resilience in Ethiopia. The study suggests that regenerative agriculture practices such as leaving residues, organic manure, cover crops, agroforestry can help regain land fertility and resilience, but its benefits weaken under warming and erratic rains.
A new tool developed by Christelle Wauthier can help forecast collapse of volcano sides, also known as flanks or slopes. The models can evaluate the potential for collapse long before ground may give way entirely and suddenly, allowing local authorities and communities to prepare and evacuate ahead of a collapse.
A study by NYU Tandon and Brookhaven National Laboratory shows that crystalline hafnium oxide substrates can provide guidelines for stabilizing the superconducting phase in vanadium silicide films. The researchers found that hafnium oxide offered greater chemical stability and suppressed unwanted secondary phases.
Hanbat National University researchers have developed a new method for enhancing the performance of solid oxide fuel cells by inducing cobalt exsolution in high-temperature oxidizing atmospheres. This process results in improved electrochemical properties and higher oxygen reduction reaction activity, making it a promising direction fo...
Researchers found that rectal bleeding increases the odds of a colorectal cancer diagnosis by 8.5 times in patients under 50, highlighting the need for symptom-driven care and lifestyle modifications to reduce the risk. The study analyzed 443 patients and identified no family history as a factor in early-onset colorectal cancers.
Researchers at Aarhus University used mini-organs to show that cervical epithelial cells actively detect and combat infections, with uninfected cells becoming immune-active. This discovery opens opportunities for mucosal vaccines and targeted treatments against STIs and infertility.
A large population-based study in Western Australia found that nearly one in four CALD children displayed vulnerabilities in at least one key developmental domain. The findings emphasize the importance of culturally sensitive education policies, stronger language support, and better collaboration to address these disparities.
The study found a significant increase in the use of weight loss drugs like semaglutide and tirzepatide among patients undergoing metabolic and bariatric surgery. The proportion of patients receiving these medications rose from 1.8% to 29.4% between 2020 and 2024, reflecting growing popularity and perceived effectiveness.
eLTER has successfully submitted its Step-1 Application to the European Commission, a crucial milestone towards becoming an ERIC. The application is currently under review and may require modifications before the final request can be submitted.
A study proposes concrete solutions to increase Africa's food production while reducing greenhouse gas emissions. Analyzing Africa and China, the research highlights water management in rice paddies, modernizing logistics chains, and improving livestock feeding to curb emissions.
Researchers found that combination of drugs effectively reduce fat accumulation in laboratory animal models of metabolic liver disease. The study suggests that this combination may also help reduce both liver involvement and associated cardiovascular complications.
Researchers at Universiti Sains Malaysia create a new material capable of capturing carbon dioxide from the air using oil palm ash, achieving impressive adsorption capacity and stability. Machine learning predictions also enabled the design of a highly optimized mesoporous structure.
A machine learning approach enhances the treatment of livestock manure, predicting phosphorus distribution and recovery. The process converts biowaste into hydrochar and a nutrient-rich liquid, reducing environmental pollution and supporting sustainable agriculture.
A study by the American College of Surgeons found that AI enhanced evacuation efficiency, optimized routes, and prioritized patients by injury severity. AI also accelerated drug delivery, identified new treatments for injuries, and supported artificial limb selection.
Researchers developed a novel spectroscopic approach to precisely analyze molecular interfaces at material surfaces. The technique uses gap-controlled infrared absorption spectroscopy, combining conventional ATR-IR with advanced data analysis, allowing for the isolation of interfacial molecular signals.
Curtin University has signed two international agreements to advance next-generation robotics and autonomous systems, with a focus on finding life on Mars. The LifeSpringsMars Working Group will unite scientists and industry experts from around the world to develop new technologies for mining, defence, and remote operations.
A new study found that untreated depression in cancer patients leads to poorer surgical outcomes, including longer hospital stays and higher mortality rates. However, treating depression with antidepressants can significantly improve post-surgical recovery and reduce healthcare costs.
A new study found that NCAA athletes who experienced more concussions reported worse health outcomes, while those in higher-contact sports and longer-term participants showed improved mental health scores. The research suggests that team environments may play a protective role in mitigating mental health deficits associated with concus...
Keck Medicine of USC has opened its largest and most advanced outpatient location in Pasadena, offering world-class services, expert physicians, and leading-edge technology. The new facility provides a wide range of clinical specialties under one roof, making care easier to access.
Researchers have elucidated the final step in the biosynthesis of iridoids, a widespread class of plant secondary metabolites with defense and medicinal properties. The discovery of an enzyme catalyzing cyclisation to nepetalactol paves the way for future biotechnological production of these compounds.
A new vaccine against elephant endotheliotropic herpesvirus (EEHV) has been shown to be safe and trigger a strong immune response, with the potential to prevent deadly EEHV disease in young Asian elephants. The vaccine was tested in adult elephants at Chester Zoo and successfully activated key parts of the immune system.
Researchers found that older mice showed less stable spatial memory and difficulty navigating between familiar and unfamiliar environments. In contrast, younger mice developed distinct firing patterns for each track, allowing them to remember hidden reward locations on alternating tracks with ease.
Researchers at UBC have successfully transplanted an enzyme-converted kidney into a brain-dead recipient, showing promise for universal donor organs in transplantation. The breakthrough uses special enzymes to remove blood-type antigens, making it possible to use mismatched organs from deceased donors.
A new study has created the largest genetic map of human metabolism, revealing key genes controlling metabolites and their impact on health. The research highlights similarities in genetic control across ancestries and sexes, offering new avenues for developing medicines to prevent heart diseases.
Researchers found that glioblastoma causes skull bone erosion, alters immune-cell balance in skull marrow, and interferes with the body's immune response. The cancer was found to be more aggressive when treated with drugs intended to inhibit skull-bone loss.
A team at Lund University has discovered a surface protein, SLAMF6, that helps leukemia cells evade the immune system. The researchers developed an antibody to block this mechanism, restoring the immune system's ability to kill cancer cells in laboratory trials and mice.
Researchers found over 20 bird species across four continents produce nearly identical whining calls when spotting parasites, suggesting a shared learned response.
Researchers have discovered a new antibiotic targeting IBD, with AI predicting its mechanism of action. The AI model successfully identified the drug's target protein complex, reducing the development time by over two years and costs to $60,000.
A new study from the University of Gothenburg reveals that trawling restrictions have led to a significant increase in marine life, particularly among filter-feeding species like mussels and soft corals. However, heat-sensitive species are declining at shallow depths due to warmer water temperatures, driven by climate change.
Pertussis in young infants can be life-threatening, with high white blood cell counts and apnea being common symptoms. Vaccination of mothers during pregnancy is critical to protect newborns against this potentially fatal illness.
Scientists have developed a device that allows them to stimulate three or five precisely defined points in the brain simultaneously, improving the technique of ultrasonic stimulation. This non-invasive method has the potential to treat various brain diseases, including Alzheimer's, epilepsy, and depression.
Researchers analyzed eye-tracking data to identify key factors influencing word processing during English reading. Word length was found to be the most critical factor in determining skipped words and total reading time, while word frequency and predictability played a significant role in initial processing and rereading.
A new study at Bournemouth University found that people with horse experience were more accurate at recognizing pain in horse faces, while those with social anxiety were better at detecting pain in human faces. The findings aim to improve animal welfare by helping owners recognize changes indicating pain in horses.
A nationwide survey of 20,000 people found that those who changed jobs in the past year reported higher rates of health symptoms. Job changers often experience more stress factors, such as late-night shifts and excessive workloads, which can negatively impact mental and physical health.
The team developed a new method to produce ultrafast squeezed light, which can fluctuate between intensity and phase-squeezing by adjusting the position of fused silica relative to the split beam. This breakthrough could lead to more secure communication and advance fields like quantum sensing, chemistry, and biology.
A decade-long field study reveals that biochar improves soil structure, fertility, and microbial activity, leading to higher soybean yields. Biochar also reshapes soil microbial communities, promoting beneficial groups and suppressing potential pathogens.
A Peking University study maps the hidden life of river carbon along the upper Yangtze River, revealing how landscape, fire, and sunlight shape the global carbon cycle. The research found that organic carbon changes as it travels from the river's high-altitude headwaters to its densely populated downstream reaches.