Fungicides used in agriculture linked to rising resistance to antifungal medical treatments, experts call for a 'One Health' approach to combat pathogens. The use of pesticides in plants may increase fungal resistance to treatments in humans and animals.
A study published in the Proceedings of the National Academy of Sciences reveals that sports fans' emotional arousal peaks during pre-game rituals, not during the game itself. Physiological data from a Brazilian soccer fan club shows sustained arousal levels comparable to the game.
Researchers discovered that children with MS show signs of accelerated biological aging, even in their teenage years, which may lead to new treatment possibilities beyond immunosuppression. The study found that youth with MS had evidence of accelerated epigenetic age, a measurement of DNA chemical modifications associated with aging.
The use of medical AI systems is compromised by inconsistent and inaccurate race and ethnicity data in electronic health records. Experts call for standardization of methods for collecting this data and warrantying its quality in AI systems.
A recent study published in Current Biology found that sauropods, a type of herbivorous dinosaur, relied heavily on their gut microbes for digestion. The analysis of plant fossils in the dinosaur's gut suggests that they engaged in minimal oral processing and instead ate bulk feeders.
Researchers at CIC bioGUNE have made a significant breakthrough in understanding the most aggressive form of prostate cancer, revealing that it behaves differently from other types. The study shows that cancer cells use a unique 'language' to communicate with normal cells, altering their behavior and benefiting the tumor.
Researchers at Rutgers University have developed a portable device capable of detecting rare genetic mutations from a single drop of blood. The device combines allele-specific polymerase chain reaction with electrical impedance to quickly and accurately test for conditions like hereditary transthyretin amyloidosis.
A new report by UCL academics finds that opening new North Sea oil and gas fields is incompatible with achieving the Paris Climate Agreement goals. The researchers recommend stopping all future licenses to explore and refusing development consent for already-licensed fields.
A new review highlights the emerging applications of spatial transcriptomics in musculoskeletal research, enabling discoveries in arthritis mechanisms and limb development. Researchers can now explore how cellular environments influence development, disease, and healing with unprecedented resolution.
A systematic review of 117 studies involving over 292,000 children worldwide found that excessive screen time is associated with socio-emotional problems like anxiety and aggression. Parents are advised to monitor their child's screen use and provide emotional support as needed.
A study by Florida Atlantic University reveals that climate shifts starting around 500 A.D. led to shorter lives and faster growth in bald cypress trees, which may have made them more vulnerable to stress. The research provides a powerful lens into how widespread environmental changes can be.
SLICE, a paradigm-shifting light sheet microscope, enables researchers to image biological samples with exceptional clarity and speed, democratizing access to advanced imaging technology. The system's compact design and affordable pricing make cutting-edge light sheet microscopy accessible to labs of all sizes.
Researchers at Karolinska Institutet found that a Western diet can cause long-lasting damage to the blood vessels of pancreatic islets, leading to impaired glucose metabolism. The study's findings highlight the importance of preserving islet vascular health in metabolic diseases.
The small intestine's epithelial cells and immune cells work together to maintain gut integrity and regulate immune responses. Dysfunction in these cellular networks is linked to systemic diseases such as obesity, insulin resistance, and autoimmune conditions.
Researchers found that osimertinib and immune checkpoint inhibitors activate the IL-6/JAK/STAT3 signaling pathway in liver macrophages, leading to a cytokine storm-like inflammatory response. Introducing JAK inhibitor ruxolitinib successfully dampened this response.
The American Psychological Association 2025 Convention will address the youth mental health crisis and the promise of psychedelic drugs. The event will also explore artificial intelligence and the healing power of kink. Reporters can register for on-site press coverage or virtual access.
Researchers developed a new computational tool using generative AI to identify key gene combinations underlying complex illnesses. The method amplifies limited gene expression data, enabling researchers to resolve patterns of gene activity that cause complex traits.
A study of nearly 600 US companies over 17 years found that firms in states with stakeholder-focused laws are better at avoiding environmental issues. CFOs' personalities, especially if they're overconfident, can lead to risky decisions harming both the environment and the company.
Pregnant individuals are at high risk of measles infection and its complications. Experts emphasize the need for urgent access to IVIG and updated hospital protocols to protect vulnerable groups.
Researchers found that the Galactic Center's star-forming regions struggle to form high-mass stars, unlike typical star-forming regions, due to extreme conditions caused by the black hole. The study suggests these regions effectively produce just one generation of stars and lack sufficient material for continued formation.
A new study reveals that 83% of ectomycorrhizal fungi are dark taxa, meaning they can't be linked to named or described species, posing problems for conservation efforts. The discovery highlights the importance of protecting these underground fungi, which regulate Earth's climate and ecosystems.
Research found that approximately 50% of participants with late-life depression and bipolar disorder showed tau accumulation in their brains, compared to only about 15% of healthy controls. The study suggests that neurodegenerative diseases, including Alzheimer's, can initially manifest as psychiatric symptoms.
Researchers developed a non-destructive method for shaping advanced ceramics in the gel state, enabling slotting, drilling, and removing with micrometer-scale accuracy. The technique, called URM, uses high-frequency ultrasonic vibration to precisely modify the gel's structure, reducing surface roughness and avoiding machining damage.
Researchers found that a specific molecule called inosine, produced by beneficial gut bacteria, plays a critical role in developing immune cells. Supplementing antibiotic-exposed infants with inosine restored normal T cell development and enhanced infection resistance in mice.
Researchers found that cigarette smoke and reduced DNA repair capacity combine to increase cancer risk, with normal lung cells showing extensive damage after smoke exposure. The study's findings support a 'double hit' model, highlighting the critical role of XPC protein in preventing DNA damage.
The new program offers minimally invasive treatments for cardiovascular issues, including transcatheter aortic valve replacement and left atrial appendage occlusion. The cardiac catheterization lab features state-of-the-art equipment, allowing improved diagnostic imaging and safer procedures.
A novel approach to synthesizing an ultra-low platinum loading ORR electrocatalyst is presented, achieving a doubling of mass activity compared to conventional catalysts. The catalyst demonstrates remarkable performance in zinc-air batteries, with impressive peak power density and excellent durability.
A study of over 2,800 adolescents found that those who got less sleep had reduced connectivity between brain regions critical for decision making and emotional regulation. This can lead to problem behaviors such as aggression and impulsivity.
Researchers develop gene pyramiding technique to combine resistance genes for robust protection against mixed begomovirus infections. This approach overcomes limitations of individual resistance genes, providing a promising strategy for sustainable crop protection in regions affected by devastating viral diseases.
Researchers have developed a new high-performance image sensor that incorporates a built-in solar cell structure using pinned-surface double-junction photodiodes. This design improves light sensitivity and reduces image lag, making it suitable for applications such as AI smart robot vision chips.
A new study explains how the gene CDK12 drives high-grade serous tubo-ovarian carcinoma, a rare and aggressive form of ovarian cancer. Researchers discovered that inactivating CDK12 triggers an immune cell response and identified a partner gene, CDK13, as a target for a degrader or inhibitor.
Researchers developed a machine learning framework that can predict how materials respond to electric fields up to a million atoms, accelerating simulations beyond quantum mechanical methods. This allows for accurate, large-scale simulations of material responses to various external stimuli.
Researchers led by Shuo Zhang used multi-wavelength studies to identify pulsar wind nebulae as potential cosmic ray sources. The findings could help unlock fundamental questions in physics, such as galaxy evolution and dark matter.
Researchers found that passionate fans show more activity in the dorsal medial prefrontal cortex during offensive faceoff opportunities, indicating emotional involvement and evaluative thinking. The study used functional near-infrared spectroscopy to track brain activity in 20 participants watching a professional European ice hockey game.
Avian embryos use modular, independent physical mechanisms to regulate their size and shape, shedding light on evolutionary plasticity of natural embryos. This discovery has implications for engineering synthetic ones, with potential applications in medicine and biomaterials.
A new study found a sharp increase in appendix cancer incidence rates for those born after 1945, particularly among Generation X and Millennials. The researchers estimated age-specific incidence rates of appendiceal adenocarcinoma per 100,000 persons between 1975 and 2019.
A study found that healthy sleep habits at age 15, including earlier sleep timing and lower sleep variability, predicted better cardiovascular health at age 22. This suggests that addressing multiple dimensions of sleep health may be crucial for promoting long-term heart health.
Researchers at the Institute of Industrial Science, The University of Tokyo, found that increasing levels of free amino acids in the culture medium can increase intracellular free amino acids and influence flavor compounds in cultured meat. Glutamic acid was the most prominent amino acid, while alanine was higher in conventional beef.
Researchers found that using Tumor Treating Fields therapy (TTFields) combined with immunotherapy (pembrolizumab) and chemotherapy (temozolomide) may extend survival for glioblastoma patients. TTFields disrupt tumor growth, attracting more immune cells to attack cancerous cells.
Researchers mapped 62 trait-associated genomic regions in bananas, offering a detailed genetic roadmap for breeding improvement. The study's Kc model overcame limitations posed by chromosomal rearrangements, revealing key QTLs for yield, plant structure, and fruit quality.
The SELINA 5th project Workshop on the Azores unified partners to enhance cross-sector collaboration, advance key tools, and foster synergies. Interactive sessions focused on Communities of Practice and Compendium of Guidance, promoting knowledge exchange and capacity building.
Researchers obtained high-resolution cryo-EM structures of IVD, revealing a tetrameric architecture and substrate selectivity. The study identifies key residues and cofactors involved in enzyme activity, enabling the development of small-molecule therapeutics to stabilize mutant IVD.
A study found that psilocybin increased overall psychological well-being, including positive changes in religious practices and attitudes. Clergy who received psilocybin reported sustained improvements in their behavior and attitudes up to 16 months after treatment.
Researchers developed a method to edit crop plant genes, discovering influence on taste and shape. The technique enables examining thousands of genes, overcoming challenges like genetic redundancy.
A recent study published in Heredity investigated whether female odour-based mating preferences can predict gamete-level compatibility in humans. Women preferred the body odours of MHC-similar men, but sperm from MHC-dissimilar men exhibited higher motility when exposed to female follicular fluid.
A recent study has gathered the first video evidence of anchoring and chain damage in Antarctic waters, highlighting a critically understudied conservation issue. The research found that anchor impacts can cause localized destruction to seafloor habitats, leading to the loss of slow-growing, sessile species.
Through the Archer Fellowship Program, UTA students spend time in Washington, D.C., completing internships and taking courses taught by UT System faculty and policy experts. The program offers unique opportunities for students to network with professionals, learn from peers, and gain insight into federal policy-making.
A new study found that taking antipsychotic medication as prescribed significantly reduces the odds of a motor vehicle crash among drivers with schizophrenia. Researchers analyzed 20 years of data and found a 50% reduction in crash risk among those who adhered to their medication.
Researchers developed a digital motor score, HDDMS, using smartphone apps to track disease progression in Huntington's disease. The HDDMS is around twice as sensitive as the current clinical measure, allowing for more efficient clinical trials and potentially accelerating drug development.
Scientists have discovered that heparan sulfate in Bruch's membrane traps lipoproteins, leading to drusen formation and vision loss. Targeting this interaction may prevent or reverse early signs of AMD.
Brain-computer interface (BCI) technology offers new hope for individuals affected by paralysis, aphasia, and neurodegenerative diseases. BCIs are poised to influence cognition, ethical governance, and national security as they transform how we interact with the world.
The article discusses how emerging contaminants like agricultural pesticides and medicines are impacting water quality in developing countries. The presence of these pollutants is linked to toxic effects on humans and ecosystems, with many being undetected or under-regulated.
A cross-sectional study found substantial cost shifting in veterans' surgical care from Medicare Advantage to Veterans Health Administration among high-veteran Medicare Advantage plans. This shift underscores the urgent need for policy reforms to improve the efficiency of veterans' care, as suggested by the findings.
Research led by Michigan State University suggests that an enzyme called NrfA can help retain nitrogen in soil, reducing the need for fertilizer and preventing harmful algal blooms. This could have significant positive agricultural implications.
Nearly 1 in 5 US firearm suicides occur outside the home, suggesting broader community-based interventions could enhance prevention strategies. The study's findings support extending existing home-based interventions to reduce firearm-related suicides nationwide.
Researchers at Harvard developed link-bots, centimeter-scale robots composed of V-shaped chains with notched links, capable of coordinated movements and emergent collective behavior. The team demonstrated link-bots' ability to move forward, stop, change direction, squeeze through gaps, and cooperate on tasks.
Researchers have made a breakthrough in understanding the molecular determinants of drug response in cystic fibrosis patients who are resistant to current treatments. By analyzing CFTR mutations, they found that some proteins can be 'corrected' and respond to FDA-approved corrector drugs.
Researchers argue that space exploration mirrors historical patterns of land appropriation and ecological harm, sidelining Indigenous knowledge systems and rights. They call for a fundamental shift towards collaboration, consultation, and mutual benefit.
Creatine has broad health benefits beyond athletic performance, including maintaining energy in stressed cells and preventing muscle loss with aging. Studies have shown no significant side effects from creatine supplementation, contradicting common misconceptions.
A powerful Coronal Mass Ejection (CME) erupted from the Sun, initiating a severe geomagnetic storm alert for Earth. The event was observed by NRL's space-based instrumentation and highlighted the importance of CME research in understanding the conditions of the Earth's magnetosphere.