Researchers at Queen Mary University of London uncover new insights into cordierite's unusual ability to resist changes in size despite significant temperature fluctuations. The team's simulations accurately reproduced experimental data, providing a comprehensive explanation for the material's behaviour at both low and high temperatures.
Researchers investigated how two CAR T cells kill cancer with distinct signaling domains. CD28.ζ-CAR molecules work quickly and efficiently, while 4-1BB.ζ-CAR molecules linger in lipid rafts for sustained collaborative killing of tumor cells. This study aims to design CAR molecules maximizing antitumor activity beyond B cell malignancies.
Pharmacy benefit managers (PBMs) steer Medicare patients to their own pharmacies, with PBM-owned pharmacies capturing over 60% market share in certain drug classes. The study suggests that the 'any willing pharmacy' rules may be preventing PBMs from gaining significant market share in Medicare.
Researchers developed a new super-resolution microscopic method to investigate the interactions of therapeutic antibodies with target molecules on tumour cells. The study reveals that all four antibodies crosslink CD20 molecules independently of type I or II classification, and that B cells take on a hedgehog shape after treatment.
Scientists at University of California - Riverside discovered a chemical produced by plants that prevents bacterial biofilm formation. This breakthrough offers potential advances in healthcare and industrial settings, where biofilms cause significant problems.
A climate fee on food could effectively cut greenhouse gas emissions in agriculture by up to 22.5% annually, according to a new study. The social cost of carbon would be reflected in food prices, with more sustainable products like vegetables becoming cheaper and meat and dairy more expensive.
A novel drug combination of albendazole and ivermectin demonstrates superior efficacy in treating Trichuris trichiura and other soil-transmitted helminths. The treatment has shown safety in a phase II-III trial, potentially aiding endemic countries in meeting the WHO's Roadmap for Neglected Tropical Diseases.
Researchers discovered valence electrons that don't contribute to magnetism form pairs exhibiting properties reminiscent of a superconducting state. At low temperatures, these pairs increase and eventually saturate, while remaining electrons form an antiferromagnetic arrangement.
The employment-to-population ratio for people with disabilities has remained stable at historically high levels, with a modest but encouraging upward trend. The labor force participation rate also increased, indicating progress in disability employment.
Researchers identified alkene ozonolysis as the dominant driver of O₃ formation during cold January days in Lanzhou, China. The study proposes actionable mitigation strategies to reduce O₃ levels by targeting alkene and nitrogen oxide emissions.
UCalgary scientists reveal a whitish grey patch associated with aurora borealis, suggesting a heat source and more complex aurora dynamics. The discovery uses advanced camera technology to capture true color images of the night sky.
A new study by Boston University School of Public Health found that lower access to air conditioning increases the need for emergency care for wildfire smoke exposure. People living in areas with low air conditioning availability are at higher risk, especially children and the Black population.
A new study suggests that current guidelines for diagnosing a potentially deadly heart condition may be missing women due to natural differences in sex and body size. The researchers developed a personalized approach using AI, which improved diagnosis accuracy by 20 percentage points for female patients.
Researchers found that biglycan preserves bone structure, while decorin significantly contributes to its mechanical properties. These proteins interact with water to regulate bone's mechanical behavior.
Hebrew SeniorLife has launched a 18-month clinical food trial to test the combination of probiotics and prebiotics for managing bone health in women aged 60. The study, funded by the National Institute on Aging, aims to investigate the underlying mechanisms leading to age-related bone loss.
The 2025 Annual College Hiring Outlook Report highlights the importance of fostering a learning environment that cultivates integrity, resilience, and adaptability. Employers value candidates with technical skills and self-management abilities, as well as those with digital literacy skills capable of navigating complex environments.
A team led by the University of Tokyo has created a nearly 20-year-long dataset of the entire atmosphere, enabling new research on previously difficult-to-study regions. The dataset spans multiple levels of the atmosphere from ground level to the lower edge of space and could improve climate modeling and seasonal weather forecasting.
A new tablet combining albendazole and ivermectin is safe and more effective than albendazole alone in treating Trichuris trichiura and other soil-transmitted helminths. The ALIVE clinical trial showed higher cure rates for T. trichiura, hookworms, and improved egg reduction rates compared to albendazole alone.
A new MOSCap device using Hafnium diselenide replicates neuron-like adaptive behavior and memory retention, enabling faster data processing and adaptive capabilities. The device maintains its data stability under stressing conditions and preserves data after removal of light stimuli.
Professor Kaibin Huang, a renowned researcher at HKU, has been elected as a 2024 Fellow of the US National Academy of Inventors. His pioneering work in multi-antenna communications, wirelessly powered communication, and edge AI has made significant impacts on quality of life, economic development, and society.
Researchers found genetic variants that confer a benefit to chimpanzees in specific habitats, particularly those related to malaria. The study suggests that climate and land use changes will impact different chimpanzee groups differently.
Researchers have identified a 177-gene signature common to metastasis across cancers, allowing for personalized risk assessment and potential therapies. The discovery could lead to broader treatment options, faster drug access, and improved patient outcomes.
Researchers at the University of New Hampshire developed an AI-powered algorithm to categorize over 706 million aurora images from NASA's THEMIS data set. This labeled database can help scientists better understand and forecast geomagnetic storms that disrupt vital communications and security infrastructure.
Researchers at the University of Pittsburgh are studying the link between walking patterns and cognitive decline to improve early detection of Alzheimer's Disease and Related Dementias (ADRD). The team hopes to unveil neural mechanisms underlying the relation between mobility and cognitive decline.
Researchers at Graz University of Technology have developed new measurement methods to accurately measure emissions from category-L vehicles in realistic operation. The project results will help law enforcement agencies detect limit violations and manufacturers adapt their fleets.
A new study reveals that job satisfaction follows a U-shaped curve among managerial and professional workers during their 40s and 50s. This challenges societal perceptions of midlife and highlights the need for workplace support for skilled workers.
Cricket frogs use a combination of underwater push and leg movement to propel themselves out of the water, resulting in a 'belly flop' motion. This discovery could lead to advancements in bio-inspired robotics and water testing systems.
Researchers at Chalmers University of Technology and University of Maryland have engineered a new type of refrigerator that can autonomously cool superconducting qubits to record-low temperatures. This breakthrough paves the way for more reliable and error-free quantum computations.
A new study by UCSF found that menopause increases the rate of MS progression in women, particularly in walking speed and fine motor skills. The study also suggests that hormone therapy may be beneficial in slowing disease progression, with some participants showing a lower rate of relapse during pregnancy.
By reducing the thickness of a commonly-used piezoelectric ceramic material, researchers at Indian Institute of Science (IISc) show that its efficacy can be dramatically increased, resulting in improved strain values. The team discovered that removing oxygen vacancies in lead-free piezoceramics also boosts electrostrain to 1% or higher.
The project creates a comprehensive U.S.-Japan flood risk data inventory and develops a two-way coupled, multi-scale, agent-based model that considers marginalized groups. Researchers will use the developed model to evaluate the impact of insurance policies on these groups.
Researchers at Binghamton University have developed a new paper-based biosensor system that uses bacterial spores to monitor glucose levels in sweat, eliminating the need for finger-stick devices. The system is shelf-stable, self-replicating, and can endure harsh environments, making it a promising alternative for diabetes management.
Research by Anqi Wei and colleagues found that neural circuits in mice are sex-specific, influencing socio-sexual preferences. Under survival stress, female mice switch to preferring males due to altered neuronal firing patterns.
Researchers at University of California, Irvine have designed a way to tag RNA with a glowing molecule for real-time tracking. This allows scientists to study how viruses propagate and understand the role of RNA in brain function and memory formation.
A series of small earthquakes in Surrey in 2018 and 2019 may have been triggered by oil extraction from a nearby well, according to a new study. The research used mathematical modeling to predict the frequency of earthquakes based on oil extraction timing and volume, finding a rough match with observed seismic activity.
A new test called ORACLE can predict lung cancer survival at the point of diagnosis better than currently used clinical risk factors. This could help doctors make more informed treatment decisions for people with stage 1 lung cancer, potentially improving patient outcomes.
A Chapman University-led study estimates that plants store about 786 km³ of water, which takes just five days to flow through them. This rapid transit time is significantly faster than other parts of the global water cycle.
Scientists have created a new method for quickly detecting and identifying very low concentrations of gases, offering promise for real-time monitoring in environmental, health, and industrial applications. The approach uses a coherent control strategy to enhance the sensitivity of quartz-enhanced photoacoustic spectroscopy.
A new study finds that sabre-toothed predators' long, sharp blades were optimal for puncturing prey. The research also challenges traditional ideas on the diversity of sabre-tooth shapes among different species.
Researchers discovered a key role for neutrophils in cancer cell colonization of abdominal fat through the release of DNA webs called NETs. Additionally, a new biomarker study found that dose-dense chemotherapy improved disease-free survival by 20% and overall survival by 15% for women with early-stage ER-positive breast cancer.
Richard Alley, a leading expert in Earth sciences, has been recognized with the prestigious National Medal of Science for his decades-long contributions to understanding the planet's ice sheets. His research has revealed key 'switches' and 'dials' in Earth's climate that can lead to significant environmental changes.
Researchers developed TLE-PINN to predict melt pool morphology in selective laser melting, achieving superior accuracy and faster training times. The framework combines physics-informed constraints with deep learning techniques, enabling precise and efficient solutions for real-time process control and manufacturing optimization.
A groundbreaking UK study found that using procalcitonin (PCT) to guide treatment decisions did not reduce antibiotic duration in hospitalized children. The PCT test was safe but costlier than standard methods, and healthcare teams faced challenges integrating it into their decision-making processes.
Scientists at the University of Florida have developed a genetically edited citrus tree that produces a protein killing baby Asian citrus psyllids, which transmit the greening disease. The approach has shown promise in controlling the spread of HLB, but adult psyllids remain a challenge.
A new study from UCLA and Oklahoma State University found that people may trust cheaters who benefit them, rather than just those who have betrayed in the past. This challenges traditional notions of trustworthiness and suggests that relationships are influenced by self-interest.
Researchers at CCNY developed a technique to manipulate relativistic electronic bandstructures using hydrogen ions, enhancing chirality of electronic transport in a magnetic material. This finding opens new quantum device platforms for harnessing emergent topological states.
Researchers found that adolescent rodents fed a high-fat diet showed poor control during motor inhibition tasks and conservative decision-making in adulthood. The study suggests that a high-fat diet in adolescence can provoke long-term changes in impulsive behavior.
Researchers at University of California, Irvine have discovered a new type of skeletal tissue that offers great potential for advancing regenerative medicine and tissue engineering. The 'lipocartilage' tissue is uniquely packed with fat-filled cells called lipochondrocytes that provide super-stable internal support.
A new discovery by Åbo Akademi University researchers enables the creation of more efficient and stable organic solar cells with an outstanding efficiency of over 18% and a lifespan of 24,700 hours. This breakthrough paves the way for larger-scale production of efficient organic solar cells.
Scientists at HIRI have made significant progress through a series of in vitro and in vivo experiments, revealing a complex RNA-based regulatory circuit governing PUL expression in B. thetaiotaomicron.
The Kinsey Institute has acquired groundbreaking research and cultural contributions from Dr. Ruth Westheimer, Dr. Helen Fisher, and Dr. Judith Allen, advancing future scholarship and research on human sexuality and relationships.
Researchers found low-configuration spectrometers matched high-end models in measuring solar-induced chlorophyll fluorescence and tracking crop growth. This breakthrough makes ecosystem and agricultural monitoring more accessible and scalable.
Researchers at the University of Parma and Sant'Anna School in Pisa developed a new approach to understand how the brain controls spontaneous movements in natural situations. The study used telemetric devices to record hundreds of neurons from the brains of monkeys, revealing complex synergies between individual neurons that allow for ...
The new FIFAWC dataset addresses limitations of existing Group Activity Recognition (GAR) datasets by annotating multiple GA instances per sample. This allows for more accurate GAR and innovative tasks like video captioning, showcasing the complexity and challenge of real-world contexts.
Researchers discovered that household dogs are a significant transmission point for zoonotic pathogens like nontyphoidal Salmonella. Proper hygiene and awareness can help mitigate cross-species infections.
Researchers found that up to 34% of the British public considered acts like nepotism or bribery acceptable during the vaccine rollout. The study also discovered an association between public tolerance of petty corruption and vaccine rollout speed, with slower rollouts in areas where tolerance was higher. Lead author Dr Franziska Sohns ...
A recent study found that a genetic test for opioid use disorder (OUD) had high rates of both false positive and false negative results, questioning its usefulness. The testing could lead to patients receiving opioids despite low risk or being denied effective pain relief due to high risk.
The Collaborative Science Pilot Awards program aims to inspire innovative research projects across UH and Case Western Reserve. Five teams will focus on organizing an MR Fingerprinting database, developing a genetic risk aid for early keratoconus detection, analyzing Alzheimer's treatment mechanisms, treating gastrointestinal symptoms ...
Researchers from NTU Singapore have developed a new crystal structure that shows naturally existing particles can behave like axions, promising to detect dark matter. The findings could lay the groundwork for understanding cosmic phenomena and uncovering the universe's greatest mysteries.
Researchers analyzed cost-effectiveness of semaglutide for non-diabetic overweight/obese individuals with heart disease. With price reductions, semaglutide shows promise in reducing lifetime costs and improving health outcomes.