Golden retrievers are at risk of a fatal heart condition due to a genetic mutation in the Cardiac Troponin-I gene. The study, published in Circulation: Genomic and Precision Medicine, identified a single genetic variant that causes hypertrophic cardiomyopathy (HCM) and sudden death in dogs.
A new approach to urban delineation uses human behavioral patterns to determine urban areas and land use. The study analyzed Points of Interest data using Kernel Density Estimation and identified five hotspots of urban activity in Pekanbaru, revealing that traditional methods often obscure the true dynamics of urban life.
A study published in Annals of Translational Medicine found that intense light therapy can lower troponin levels and increase ANGPTL4 protein, protecting heart tissue. The treatment may reduce the risk of myocardial injuries after non-cardiac surgery, which affects 20% of patients and increases one-year mortality rates.
First-year university students with overly cautious parents experience increased anxiety when faced with stressful situations. The study found that overprotective parenting can lead to insecure attachment and poorer emotion regulation, making individuals more vulnerable to anxiety.
The BETAMI and DANBLOCK trials found that beta-blocker therapy significantly reduced all-cause mortality and major adverse cardiovascular events in patients with myocardial infarction and preserved or mildly reduced left ventricular ejection fraction. The study also showed a notable decrease in the incidence of new MI.
Researchers Jeremy McCormack and Andrei Kuzhelev at Goethe University are investigating the reasons behind prehistoric shark extinctions using new isotopic analysis methods. They also develop a novel nuclear magnetic resonance spectroscopy technique to study large biomolecules.
Researchers at IBEC are developing new techniques to study enzymes that erase microtubule modifications, which have shown promise as therapeutic targets. The goal is to understand these mechanisms and develop new treatments for cardiac and neuronal disorders.
A recent study published in Biomass and Bioenergy found that ash can increase methane production in anaerobic digestion of biowaste, improving the quality of resulting fertilizers. Adding trace elements from ash can have a complex effect on the process, but it also increases plant growth and reduces acidity.
Researchers have discovered forehead teeth on spotted ratfish, which are used for mating and challenge traditional conceptions of dental history. The findings provide evidence that these unusual structures are indeed teeth, not denticles, and shed light on the evolution of oral teeth.
A novel explanation for deadly cardiac events is that neutrophils release a peptide that punctures stressed heart cells, destabilizing their electrical activity and promoting life-threatening arrhythmias. This finding offers a potential therapeutic target for treating ischemic heart disease.
Recent species-level extinctions are high, but genus-level losses are rare and localized, occurring mostly on isolated islands. The study found that modern extinction rates have not been increasing over the past century, contrary to previous studies.
Ibezapolstat, a new antibiotic, has been shown to be effective in treating Clostridioides difficile (C. diff) infections with high rates of sustained clinical cures. The study found that ibezapolstat killed harmful bacteria without harming the good bacteria in the gut, which helps prevent recurrent C. diff infections.
The European Society of Cardiology has published a new update to its guidelines for managing lipid levels in patients to reduce cardiovascular risk. The guidance recommends the use of new cardiovascular risk prediction algorithms, SCORE2 and SCORE2-OP, to help clinicians treat patients with the right medications. Statins are also recom...
Researchers found that correcting myths with facts strengthened people's intentions to get vaccinated, making myth-busting strategies a key to broader vaccine distribution. The study suggests three effective strategies for debunking false information about COVID vaccines.
Researchers identify kinases, MYB transcription factors, and zinc finger proteins as key players in controlling litchi bud dormancy. The study provides the first comprehensive phosphoproteomic map of litchi bud dormancy, offering insights into perennial bud regulation mechanisms.
Researchers developed an acid-resistant hydrogel called ultrastable mucus-inspired hydrogel (UMIH) that improved gastrointestinal wound healing in animal models and outperformed a clinically approved mucosal protectant. UMIH showed 15 times stronger adhesive abilities and remained stable for 7 days in acidic conditions.
A team of researchers from the University of Ottawa has developed a new workflow to study autophagy, a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out components. The study reveals novel signaling mechanisms regulating autophagy in response to numerous disease-related stress conditions.
Researchers at TUM Institute of Engineering have accurately measured the Earth's axial movement using a ring laser over a 250-day experiment. The results reveal small wave movements in the precession circle of the Earth's axis, known as nutation, with varying degrees of intensity.
UCSB researchers warn that the ocean's cumulative impact will double by 2050 due to climate change and human activities. The tropics and poles are expected to experience the fastest changes in impacts, with coastal areas bearing the brunt of the increased pressures.
A new study reveals that estrogen-regulated signaling promotes the regeneration of key filtration cells in female kidneys, protecting against chronic kidney disease. The study also links pregnancy complications like preeclampsia to failures in this regenerative process.
Dr. Vasily Sotnikov has been awarded an ERC Starting Grant to develop new computational methods for particle scattering calculations at the LHC, enabling precise predictions for Higgs boson interactions and testing electroweak symmetry breaking.
A comprehensive cardiovascular screening program for men aged 60-64 years did not significantly reduce all-cause death, according to a new study. However, the program was associated with a higher incidence of severe bleeding, particularly intracranial and gastrointestinal bleeding.
A Taylor & Francis journal has found high levels of author satisfaction with the quality, speed, and decision-making under a transparent peer review model. Authors valued constructive feedback, and most reported they would submit or review again due to the journal's support for transparency.
Scientists have identified the mechanism linking a mutation in the Shank3 gene with alterations in social behavior, revealing that vasopressin plays a crucial role in regulating sociability and aggression. The study shows that targeting specific vasopressin receptors can restore social abilities without affecting aggression.
A study by Waseda University researchers found that cultural cognitive biases impact the explicit aspects of visuomotor adaptations, influencing motor learning outcomes. The findings suggest that verbal reports used in rehabilitation and sports training may be misinterpreted due to cultural prejudices.
The MIT Press is partnering with Duke University Press and Goldsmiths Press to expand its Direct to Open (D2O) open access model for monographs. This partnership aims to bring more vital research to communities that need it most, furthering the shared mission of building a more open and accessible future.
Recent physicochemical technologies for PFAS removal have been summarized in a comprehensive assessment, offering guidance for sustainable solutions. The methods are capable of breaking PFAS's strong carbon–fluorine bonds, achieving removal rates exceeding 90%.
Scientists develop magnetic nanohelices with precise spin control, achieving polarization of over 80% and paving the way for practical spintronic applications. The breakthrough utilizes chiral organic molecules to regulate electron spin direction.
A UNIGE team has discovered a 9,000-year-old quartz knapping workshop in Senegal, providing new insights into the stone-knapping techniques used by West Africa's last hunter-gatherers. The findings suggest technical similarities among these communities and potential shared traditions.
Researchers uncover how cerebrospinal fluid dynamics drive tumour spread, identifying a way to target this process to inhibit metastasis. The study provides new insights into the role of fluid shear stress in shaping cancer behaviour and offers a promising therapeutic approach for medulloblastoma.
A CISPA researcher has been awarded an ERC Starting Grant to tackle the issue of data leaks in large AI models. The project aims to develop new methods for protecting private training data, making it a crucial step towards ensuring trust in artificial intelligence.
USC Stem Cell scientists have developed a blueprint for generating specific kidney cell types on demand, holding immense value for preclinical studies of new therapeutics and congenital kidney diseases. The team successfully created lab-grown proximal tubule cells that can absorb sugar and protein, respond to chemotherapy drugs, and pr...
Researchers at Saarland University discovered that molecular dipoles in ice and shoe soles interact to create a disordered, amorphous structure on the ice surface. This interaction causes the ice to become slippery, leading to slips and falls, rather than pressure or friction.
Researchers found that nutrients can increase seagrass's ability to store carbon, but an overload of nitrogen can lead to increased phytoplankton growth, shading out and killing seagrass. Increasing phosphorus and nitrogen in nutrient-poor beds helps seagrass grow, storing more carbon.
Researchers at Brown University developed an image processing technique that harnesses camera motion to increase resolution, producing super-resolution images with details sharper than the original pixel array allows. The technique has potential applications in archival photography and photography from moving aircraft.
A clinical trial found that pork-based meals supported better recovery, mood and anabolic status in military cadets compared to plant-based meals. Cadets who consumed lean pork-based meals showed reduced muscle soreness and inflammation, while improving testosterone levels.
Researchers discovered a specific cell that responds to environmental toxins found in cigarettes, leading to aggressive tumor growth in mice with pancreatic cancer. The study also identified a type of immune cell that fuels this response while stopping the immune system from fighting tumor growth.
Researchers at UCR have developed a method to preserve AI safeguards in open-source models by retraining internal structure to detect and block dangerous prompts. The approach avoids external filters or software patches, instead changing the model's fundamental understanding of risky content.
Researchers are exploring the therapeutic potential of phage-based treatments, focusing on RNA phages that can hijack bacterial cell machinery and produce new phages. This study aims to elucidate the unique lifestyle of RNA phages and develop novel biotechnological tools for treating multi-resistant bacteria.
A study reveals how wax content, stomatal behavior, and ABA levels work together to resist fungal invasion in yams. High-quality, disease-resistant varieties can be developed through breeding or biotechnological approaches.
A new study from Memorial Sloan Kettering Cancer Center shows the Make-an-IMPACT program improves global access to genomic testing for pediatric cancer patients. The program helps develop an experimental antibody that shows promise against metastatic cancer. Researchers also shed light on the origins of ERG-driven prostate cancer and f...
Scientists discovered that human melanoma cancer cells behave like stem cells when forced through channels narrower than 10 micrometres, gaining traits to survive, spread, and form new tumours. Researchers created a biomedical device to simulate blood flow through narrow blood vessels, showing the mechanical pressure makes cancer cells...
Atrial fibrillation (AF) screening with ECG patches led to a modest increase in AF diagnosis and anticoagulation exposure among older patients at moderate-to-high stroke risk. The AMALFI trial found a 6.8% increase in AF diagnosis, but AF diagnosis unrelated to the patch occurred more commonly than expected.
Researchers Kevin Campbell, Louis Kunkel, and Eric Olson are honored for their discoveries revealing the biological causes of Duchenne muscular dystrophy, providing a foundation for new treatments. Their work has advanced scientific understanding and brings hope to families affected by this devastating disease.
Researchers at University of Würzburg uncover a previously unknown type of assembly chaperone in poxviruses, formed by an RNA molecule called tRNA. This discovery sheds light on the complex process of gene expression in viruses and could pave the way for new drugs against poxviruses.
A national survey found that 44% of US college students feel coerced into participating in animal laboratories, with 20% stating they would participate anyway to avoid problems. The college has killed thousands of animals for over 50 years, despite alternatives being available.
A new University of Georgia study found that childhood exercise habits can significantly impact adult physical health, with healthier habits in adolescence setting the stage for a lifetime of fitness. The study suggests that maintaining these habits is crucial to preventing cardiovascular disease and obesity.
Researchers used AI to identify four times more earthquakes than earlier tools and pinpoint previously unknown faults in the region. The study expands seismicity recorded by monitoring stations from 2022 to 2025, revealing two faults converging under the town of Pozzuoli west of Naples.
The Earth BioGenome Project aims to create a digital library of DNA sequences to preserve and protect life on Earth. The project has revealed a refined strategy to scale up the sequencing of 150,000 species, accelerating biodiversity research and global conservation.
The European Research Council has selected 478 early-career researchers across Europe for Starting Grants, totaling €761 million. These grants support diverse research fields, including cancer, mental health, and quantum science.
A major study found that people who walk a lot have less back pain than those who don't, with the volume of walking being more important than intensity. Walking over 100 minutes daily reduces chronic low back pain risk by 23%.
Researchers have developed a new method to accurately measure the acidity of PFAS, finding some to be thousands of times more acidic than previously thought. This breakthrough could help track the persistence and spread of these toxic chemicals in the environment.
The European Society of Cardiology recommends systematically screening for mental health symptoms during cardiovascular care and assessing cardiovascular risk in those with mental health conditions. People living with both conditions have worse health outcomes due to the interplay between mental health and cardiovascular disease.
A new scientific review reveals that stress, hardship, and social challenges reshape a person's gut bacteria and brain performance, making it harder to keep weight off. Social determinants of health play a key role in obesity risk, and addressing these conditions is crucial for long-term solutions.
A study by McGill University researchers found that biases and stereotypes influence healthcare staff's decisions to administer sexual assault evidence kits in rural hospitals. Survivors of sexual assault from marginalized groups face systemic barriers to accessing these kits, which are essential for documenting injuries and gathering ...
The ASTRO's 2025 Annual Meeting will feature pivotal studies in radiation medicine, highlighting advances in radiopharmaceutical therapy and new indications for low-dose radiation therapy. The meeting will also explore cutting-edge techniques for prostate, breast, lung, and other common cancers.
The University of Würzburg has been recognized with six European Research Council (ERC) starting grants, awarded to talented young researchers. The grants are worth €1.5 million each and will support research projects in areas such as language decipherment, insect navigation, light pollution, emotions, and energy storage.
A Washington State University-led team has designed a robotic harvester that can detect and classify hidden strawberries 80% of the time. The harvester uses a combination of artificial-intelligence vision system, soft silicone grippers, and a fan to gently move leaves out of the way, improving picking efficiency.
Researchers at Ohio State University discovered that adding an electrical jolt to fermentation increases the yield and speed of platform chemicals from industrial food waste. Combining two bacterial species also enhances targeted chemical production and produces hydrogen gas as a byproduct, reducing waste and greenhouse gas emissions.
A large trial found that mavacamten treatment did not improve patient-reported health status or peak oxygen consumption in patients with symptomatic nonobstructive hypertrophic cardiomyopathy. The study included 580 patients and lasted for 48 weeks, but no significant differences were observed between the mavacamten and placebo groups.