Researchers developed machine learning models to predict cancer risk using routine clinical data, achieving promising results for lung, oesophageal, and liver cancers. However, performance varied across cancer types, and further studies are needed to establish whether this approach improves early detection and patient outcomes.
A team of researchers has assembled a chromosome-level genome of a newly developed elite cultivar of Coptis chinensis and deployed a machine-learning model to uncover hidden patterns of genetic variation. The work identifies a key gene that regulates leaf wax production and disease resistance, opening a pathway for molecular breeding i...
Joshua Angrist, Nobel Laureate and Ford Professor of Economics at MIT, received an Honorary Doctorate from Hebrew University for his groundbreaking contributions to economics. He was recognized for his research on natural experiments and econometric tools to analyze social and economic phenomena.
Patients who received high-dose EPA before and after surgery for colorectal cancer liver metastases had longer overall survival compared to those receiving placebo. However, EPA did not significantly improve progression-free survival, the trial's primary endpoint.
Turing Award winner Shafi Goldwasser has made significant contributions to cryptography, computational complexity, and probabilistic algorithms. She is currently dedicating her research efforts to building responsible and safe AI.
Nobel Laureate Joel Mokyr received an honorary doctorate from the Hebrew University of Jerusalem, honoring his contributions to understanding technological progress and long-term economic growth. The prestigious award recognizes his decades-long research on the cultural, institutional, and behavioral forces driving innovation.
Dr. Gad Avigad's $1.5M legacy gift establishes the Gad Avigad Chair in Biochemistry at Hebrew University. Professor Danny Ben-Zvi holds the chair and conducts research on endocrinology, metabolism, and metabolic diseases.
Marc O. Mayer, a dedicated supporter of Hebrew University, received an honorary doctorate for his outstanding career in financial services and leadership roles. He has held positions at various institutions, including the University's Board of Governors and Executive Committee, as well as American Friends of the Hebrew University.
The Hebrew University of Jerusalem honored Rabbi Dr. David L. Blumenfeld, a distinguished Jewish leader and educator, with a Wall of Life ceremony. The event supported student scholarships and academic programs, extending the family's connection to the University.
Sabine Schmidtke, a renowned Islamic History researcher, received an honorary doctorate from the Hebrew University of Jerusalem in recognition of her pioneering research on the interrelations and connections among different strands of intellectual inquiry. Her work has transformed perspectives on Islamic and Jewish intellectual history...
Nobel Laureate Alvin E. Roth received an honorary doctorate from the Hebrew University of Jerusalem for his pioneering work in game theory and market design. His research has revolutionized fields such as organ transplantation, school choice systems, and labor markets.
Researchers at UT MD Anderson presented findings on cancer interception vaccines, ctDNA clearance and targeted therapies for various cancer types, including lung, breast, and skin cancer. These innovative approaches aim to strengthen and sustain immune responses, improve treatment outcomes and prevent cancer development.
A new AI framework, DS-GAT-CP, overcomes the 'abundance paradox' in gut microbiome-based type 2 diabetes classification by capturing conserved ecological patterns. The framework consistently outperforms conventional machine learning algorithms in cross-regional and cross-population validation scenarios.
Researchers used fractional calculus to create a one-dimensional model with nonlocal interactions, displaying correlation scaling similar to the two-dimensional BKT transition. However, the model lacks a conventional stiffness jump, exhibiting an unusual combination of analogy and difference in response to a global phase twist.
Researchers investigate Japan's first climate transition bonds, finding that investors demand higher returns due to uncertainty about environmental improvements. The study highlights the importance of clear transition plans and transparent reporting to strengthen investor confidence and reduce financing costs.
Researchers at the Center for Astrophysics | Harvard & Smithsonian have developed Lumina, the largest and most detailed simulation ever created of the early universe. The simulation recreates how ordinary matter, dark matter and radiation interacted during the universe's first 2 billion years, giving scientists a powerful new tool ...
Researchers at the University of Johannesburg found that airborne ESKAPE bacteria can survive exposure to first-line and last-resort antibiotics, making them highly resistant to treatment. The study's findings highlight the need for improved infection control measures in high-risk areas, where HIV and TB infection rates are high.
The Stanford Natural Capital Alliance and IDB launched new resources to support applications of natural capital approaches worldwide. The resources include a free MOOC and online Implementation Toolkit, distilling lessons from the People, Planet, Prosperity project.
Patients with KRAS-mutated lung cancer treated with divarasib lived a median of 18 months and experienced improved disease control compared to standard therapies. Divarasib reduced the risk of cancer progression by 42% and death by 44%, with fewer severe side effects reported.
The London Register of Subsurface CO₂ Storage reports a record 43.6 million tonnes of CO₂ stored in 2024, with cumulative storage reaching 421.7 million tonnes over the past three decades. The Register tracks geological CO₂ storage, which is expected to become a leading technology for mitigating climate change by mid-century.
New research found that SGLT2 inhibitors reduce all-cause mortality and major adverse kidney events by 18% and 22%, respectively, in adults aged 80 years or older with CKD. However, these medications may also increase the risk of specific cardiac events and acute kidney injury in this demographic.
A Rutgers study found that 1 in 3 young adults (18-29 years) use AI for substance-use information, primarily seeking risks and consequences. The study highlights the need for research on how young adults interpret and understand AI outputs on substance use, with implications for public health.
A new study reveals that airflow can cool UV-C lamps, altering their output and reducing airborne particle exposure time. Researchers found that higher-power lamps maintained stable output, while lower-power lamps were more sensitive to airflow and temperature fluctuations.
A new immunotherapy combination extends survival in patients with advanced endometrial cancer, with patients receiving durvalumab plus olaparib living almost one year longer than those treated with chemotherapy alone. The treatment was particularly effective for patients with mismatch repair proficient tumors, who have traditionally ha...
A new EU project, TETTRIX, aims to integrate European taxonomic data, tools, and expertise to inform biodiversity conservation and ecosystem resilience. The project will develop innovative tools and services to advance species identification and strengthen the connection between taxonomic knowledge and policy-making.
A Keck School of Medicine of USC research study found that an experimental drug called cinaciguat reverses the effects of aging in the liver, potentially lowering the risk of Alzheimer's disease and heart disease. The treatment also normalizes amyloid beta and LDL levels, which are associated with Alzheimer's and atherosclerosis.
Researchers found that commonly used kidney function tests, such as estimated GFR, significantly underestimate chronic kidney disease in patients with cancer. This discrepancy can lead to inadequate treatment decisions, including dose adjustments for anticancer therapy. The study suggests that errors in GFR estimation may contribute to...
US-Mexico border counties experience disproportionately elevated rates of death from chronic kidney disease (CKD), with reduced availability of nephrologists. The findings highlight a growing kidney health disparity, with counties having the lowest nephrologist density having substantially higher mortality rates.
The Phase 2 BESTOW trial shows that tegoprubart preserves kidney function and improves quality of life in kidney transplant recipients. Tegoprubart-treated patients had greater kidney function benefits and improved health-related quality of life compared to tacrolimus-treated patients.
A significant spike in suicidal thoughts, planning, and attempts among older US adults was found in the years following the COVID-19 pandemic. The study's findings suggest that traditional risk factors may not be the only factors at play, and that a broader risk assessment approach is needed to identify older adults at risk.
Researchers analyze a new sediment core in southern Sweden, finding microspherules and platinum-rich nanoparticles suggesting an extraterrestrial event triggered the Younger Dryas cooling. The study expands the European archive, separating the Laacher See eruption, Younger Dryas Boundary, and cooling event.
Kessler Foundation was recognized as one of America's Best Workplaces for 2027, highlighting its collaborative environment that supports professional growth. The foundation's commitment to employee growth and development is reflected in its recognition as a Best Place to Work for Women in 2026.
Everleap Fertility will deliver 19 scientific presentations at the ASRM Annual Scientific Congress & Expo, exploring topics like endometrial thickness and cycle cancellation, and the impact of maternal obesity on embryonic aneuploidy. The research aims to improve clinical processes and patient outcomes across the fertility industry.
Researchers at UC San Diego used new airborne lidar to map cliff erosion and retreat, finding that change was highly uneven along the California coast. Hotspots were identified in Central and Northern California, with some areas experiencing retreat rates exceeding 70 feet per year.
A computational model generates a digital twin of the human thorax to predict the path of light radiation and tailor noninvasive therapies to each patient's anatomy. This allows for personalized dosimetry and a more effective therapeutic response in the treatment of pneumonia.
Small cell lung cancer cells are equally dependent on cysteine, but react differently when deprived of it. Cells with low ASCL1 levels die via ferroptosis, while those with high ASCL1 levels are protected and can evade treatment. The study provides a potential starting point for new therapeutic strategies.
A new vaccine has shown promise in generating an immune response against KRAS mutations in pancreatic cancer, with patients who developed stronger immune responses showing longer disease-free survival. The vaccine targets seven common KRAS mutations and has the potential to improve treatment outcomes for patients with pancreatic cancer.
The study found that Nematostella carries eight of the ten proteins humans use to pair and align meiotic chromosomes, making it a promising system for understanding human fertility. The sea anemone's proteins show unexpected flexibility in their roles, revealing new insights into meiosis and its potential impact on fertility.
Researchers found that larger movements improve learning on similarity-based categories, but not on rule-based categories. The study suggests that movement shapes learning itself, rather than just responding to visual stimuli.
Cancers can evade chemotherapy by entering a 'zombie-like state' called premature senescence, which tricks the immune system into helping malignant cells. This phenomenon allows tumours to acquire extra oxygen and nutrients, making them more resistant to chemotherapy.
A study discovered that an ancient viral remnant in chimpanzee DNA silences a key gene, LINC00662, which is active in humans and plays a role in early brain development. This finding highlights the importance of understanding gene regulation and its potential link to brain diseases.
Researchers at the Centre for Genomic Regulation have discovered a six-gene scoring system that reliably predicts patient survival in acute myeloid leukemia. The PHFScore system, which combines the activity of six genes, can divide patients into groups with sharply different survival prospects.
A new study reveals evidence of east-west genetic exchange and long-term population continuity in southwestern Europe, linking populations across thousands of years. Genetic data from rare human remains and cave sediments provide key insights into the Gravettian culture.
Researchers at the University of Melbourne found that knowing the Pacific Ocean's state at the beginning of a forecast can provide valuable clues about a forecast's reliability one year later. Forecasts initiated during La Niña conditions consistently performed well, while those starting from neutral conditions were less reliable.
Researchers at the University of Pennsylvania have developed a novel insulator using stacked Mylar sheets, which combine strong thermal insulation with mechanical durability. The material, called hybrid layered insulating film stacks, has been tested in a vacuum and shown to maintain its thermal performance under compressive stress.
The TOSYMA study found that tomosynthesis detected significantly more invasive breast cancers than mammography, with a 24% lower rate of interval cancers over two years. This suggests that tomosynthesis may be more effective in preventing aggressive interval cancers.
Farell Keiser, a high school student, published a paper in Physical Review B as the first author, showcasing his substantial contribution to the field of terahertz research. His work focused on zinc telluride and demonstrated a more accurate physical description of terahertz generation in the material.
Researchers developed a new genetic animal model that closely follows UCP1 expression in brown and beige fat, reducing unintended genetic activity in the brain and other tissues. This model provides a precise way to study the contribution of thermogenic adipose tissue to metabolism, energy expenditure, and metabolic health.
A Northwestern University study found that disaster recovery efforts provided temporary boosts in mental and physical health for younger and retired men, but middle-aged men and elderly men did not experience similar benefits. As recovery activities ended, the boost declined, leaving elderly men worse off in the long run.
The therapy showed consistent efficacy and a manageable safety profile, with outcomes similar to those in the VISION trial. The findings support the use of PSMA-targeted radiopharmaceutical therapy in routine care for patients with mCRPC, including those eligible for retreatment.
Researchers evaluated PET imaging with radiolabeled trastuzumab deruxtecan and targeted alpha therapy against HER2-positive cancer cells, revealing promising results in tracking therapy accumulation and suppressing tumor growth. PET imaging also linked metabolic patterns to pancreatic tumor outcomes and identified potential distant met...
Henry Ford Health has enrolled the first US patients in a clinical trial evaluating pulmonary artery denervation, a treatment for pulmonary hypertension related to heart disease. The trial aims to determine the safety and effectiveness of the investigational treatment.
A new analysis of a phase 3 clinical trial found that daraxonrasib improved survival compared with standard chemotherapy across multiple groups of patients with advanced pancreatic cancer. The treatment consistently provided a benefit regardless of tumor RAS mutation status or previous treatment history.
Researchers have identified two new mushroom species in Japanese lawns, revealing overlooked fungal diversity in managed environments. The discoveries extend the species' known distributions eastward and suggest an association with disturbed grasslands maintained through human activity.
A new AI model, developed by the University of Cincinnati Cancer Center, aims to improve breast cancer survival prediction by combining statistical methods and deep learning. The model analyzes clinical and genetic data to provide more personalized care decisions for each patient.
Researchers at St. Jude Children's Research Hospital uncovered a mechanism behind PARP1-mediated DNA repair, revealing a previously undescribed role of the enzyme in chromatin remodeling. This discovery has implications for cancer treatment, as it may provide a way to target cancer cells while sparing healthy tissues.
Cases of Ebola in Kenya and Nigeria highlight the need for preparedness, with the EU/EEA population considered at very low risk of infection. ECDC emphasizes the importance of continued preparedness and adherence to recommended precautions to prevent the spread of the virus.
Chilean researchers are calling for accelerated action to address the biodiversity crisis, emphasizing the need for resources, international cooperation, and scientific tools to implement global commitments. The Institute of Ecology and Biodiversity is highlighting the importance of conservation financing and scientific validation to e...
A new study examines the impact of Operation Soteria on rape and serious sexual offence cases, finding progress in victim-centred investigations but challenges in the court system. The report highlights the need for a whole-system approach to tackle rape and serious violence, ensuring swift, fair, and responsive justice for victims.
A national study of 18,000 LGBTQ+ college students found that those experiencing discrimination are more likely to experience depression, anxiety, and suicidal thoughts. The study highlights the need for colleges to address discrimination as part of comprehensive suicide prevention efforts.