Research teams from Tulane, LSU, and University of Edinburgh found that endocannabinoids play a role in regulating the neuroendocrine stress response and influencing social behavior. Endocannabinoids may have potential therapeutic applications in diseases such as multiple sclerosis and epilepsy.
New study finds bipolar disorder prevalence higher than previously thought, with a significant economic burden and high risk of suicide; Lithium treatment may help reduce these risks.
Research identifies genetic linkages associated with bipolar disorder, including a possible connection to autoimmune thyroiditis. The findings suggest that identifying these genetic markers could help develop more effective treatments or prevent the disorder in at-risk individuals.
A study based on US National Comorbidity Survey Replication data found that 26.2% of adults in the US had a mental disorder, with anxiety disorders being the most prevalent. Severity levels showed 22.3% as serious, 37.3% as moderate, and 40.4% as mild.
Researchers found that high cortisol levels lead to poor memory performance and a smaller hippocampus in older adults. Stress also affects young adults and children, causing reversible memory impairments and higher cortisol levels in low SES children.
Infants of mothers with posttraumatic stress syndrome disorder (PTSD) symptoms after 9/11 have significantly lower cortisol levels compared to those born to mothers without the condition. This effect is observed both in utero and after birth, suggesting a potential biological risk factor for PTSD.
Research suggests that post-traumatic stress disorder (PTSD) is a significant concern among refugee populations in western countries. Studies indicate that approximately 1 in 10 adults experience PTSD, while others may struggle with major depression and generalized anxiety disorders. The findings highlight the need for increased attent...
A study of 160 children found that 65% were exposed to violence, leading to traumatic stress reactions and poor health outcomes such as allergies, asthma, and ADHD. Clinical interventions to improve mothers' safety and health may help protect their children from these effects.
A study found that bipolar disorder is prevalent among patients in an urban primary care clinic, with 9.8% screening positive for the condition. Patients who screened positive reported worse health-related quality of life and social impairment compared to those who did not screen positive.
Researchers found that Whites perceive significantly more disorder than Blacks, Latinos, and Asians, even when living in the same neighborhood. The study suggests implicit bias in perceptions of disorder contributes to continued racial segregation in the US.
Researchers have identified significant differences in brain chemistry between people with and without bipolar disorder using MR spectroscopy. The study's findings suggest that this imaging tool may help distinguish bipolar disorder from major depression, improving treatment outcomes.
Researchers at Children's Hospital of Philadelphia found that family therapy significantly reduced post-traumatic stress symptoms in adolescent cancer survivors. The treatment combined cognitive-behavioral therapy with family therapy and showed strongest effects on adolescents and their fathers.
A study found that stress hormones lower the threshold for aggression, while aggression raises stress hormones, leading to a feedback loop. This cycle may contribute to the escalation of violent behavior under stressful conditions.
Researchers found that acute stress increases levels of DHEA-S in healthy humans and the DHEA-S-cortisol ratio is associated with reduced dissociation symptoms. The study suggests that augmentation of DHEA-S levels before stress exposure may provide a protective effect against stress-induced symptoms.
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) survey found that over 16 million Americans had a personality disorder, with avoidant, dependent, and paranoid disorders more prevalent among females. The study highlights the importance of addressing these conditions to prevent further impairment.
A UCSD research team found that a specific transcription factor plays a crucial role in cells' ability to adapt to osmotic stress, which can lead to immune system dysfunction and cancer progression. The study's findings offer new possibilities for developing drugs to treat autoimmune diseases, transplant rejection, and cancer.
Women with PTSD experience more medical conditions and poorer physical health compared to those with depression or no history of mental health issues. The study found that PTSD affects 17% of women under 45, while depression rates are higher in older age groups.
A study by UT Southwestern Medical Center researchers found that patients who broke bones in traumatic accidents often experience Post-traumatic Stress Disorder (PTSD), with almost 51% of civilian orthopaedic trauma patients displaying symptoms. The more severe the injury, the higher the likelihood of PTSD.
A study found that lifetime exposure to adversity is associated with an increased risk of developing depressive or anxiety disorders in young adults. The researchers analyzed data from 1,803 interviews and found that the level of adversity was a significant predictor of these disorders.
Research reveals that stress triggers a hormonal response that modifies immune system function, leading to increased vulnerability to mental and physical diseases. Stress can create long-term damage by initiating an inflammatory state in the body, which can lead to chronic diseases such as depression and coronary artery disease.
The study found that 92.5% of detained juveniles experienced one or more traumatic events, with boys reporting more experiences than girls. The prevalence of post-traumatic stress disorder (PTSD) was also higher among this population, particularly among those who reported witnessing violence.
Researchers found that acute stress symptoms were common among injured children, but only a small percentage met criteria for post-traumatic stress disorder (PTSD). The study suggests that more research is needed to develop better predictors of PTSD in children.
Research finds that childhood abuse is a significant predictor of comorbid anxiety disorders, including social phobia, agoraphobia, and posttraumatic stress disorder (PTSD), among adult alcoholics. This study highlights the importance of assessing childhood trauma in evaluating and treating alcoholic patients.
Researchers found that patients who lost consciousness for at least 12 hours were less likely to develop posttraumatic stress disorder compared to those who remained conscious. The study, which examined 46 inpatients with traumatic brain injuries, suggests that losing consciousness may be a protective factor against developing PTSD.
Researchers found that female rats were more sensitive to stress-induced memory errors when estrogen levels were high. Eliminating estrogen from their system reduced this sensitivity, suggesting a key role for estrogen in the vulnerability of women to stress-related mental illnesses.
Researchers found that elevated molecular chaperones promote longevity in C. elegans, a roundworm whose biochemical environment is similar to humans. This suggests that brief exposure to environmental and physiological stress can have long-term benefits to cells by unleashing molecular chaperones.
Research suggests that high levels of estrogen can enhance the stress response, leading to greater stress-related cognitive impairments in females. This disparity is consistent with reports of higher prevalence of stress-related disorders in women, particularly during child-bearing years.
A study by Ohio State University found that financial stress was a significant contributor to depression in breast cancer patients, even stronger than grief from a loved one. Researchers analyzed data from 210 women with stage II or III breast cancer and found a strong link between money-related stress and depressive symptoms.
A study by Rutgers University researchers found that female rats during the postpartum period are less anxious and more resistant to stress than females without offspring. This unique response may be linked to the high incidence of mental illness in new mothers, including depression and anxiety.
Research on fear extinction suggests that cognitive enhancers like D-cycloserine can accelerate the learning process of fear extinction, leading to more rapid and lasting reductions in phobias. Virtual reality therapy combined with DCS resulted in significant improvements in patients' anxiety levels.
Researchers found that adolescents with impaired stress-induced pressure natriuresis showed increased urinary creatine levels and higher blood pressure after stress, indicating excessive kidney workload. This response pattern may lead to early development of renal disease.
A Yale University study found that supported housing programs for homeless veterans were more effective than standard care in reducing homelessness. The study showed a 25% increase in nights housed and larger social support networks among participants receiving combined housing vouchers and intensive case management.
A recent study found a statistically significant positive relationship between stress and breast cancer, independent of potential confounding factors. Women who experienced stress had double the risk of developing breast cancer over a 24-year period compared to those with no stress.
Researchers discovered that glucocorticoid steroid hormone promotes pleasure-seeking behaviors, including eating high-energy foods, in response to chronic stress. This finding suggests that comfort food could be a natural way to curb chronic stress and its negative effects on the body.
A new screening tool called STEPP helps predict posttraumatic stress disorder (PTSD) in children after a traumatic injury. The tool assesses event-related factors, physiological reactions, and psychological responses to identify at-risk children, allowing for early referral and intervention.
Postconflict psychiatric research reveals high prevalence of common mental disorders, particularly post-traumatic stress disorder and anxiety disorder. Exposure to violence is a potent risk factor for various disorders, with comorbidity analyses showing complex relationships between disorders.
A study led by Darlene Francis found that early-life environments significantly impact stress behaviors and learning abilities in mice. Mice transferred to high-stress surrogate mothers after birth showed increased stress-reactive behaviors and poorer cognitive performance compared to those raised by low-stress mothers.
Researchers studied 65 families with bipolar disorder and found strong genetic 'linkage' to specific regions on chromosomes 13 and 22, suggesting common genes contributing to both bipolar disorder and schizophrenia. These overlap genes may explain why the same anti-psychotic medications are effective treatments for both diseases.
A study by Maria A. Oquendo and colleagues found that people with comorbid posttraumatic stress disorder (PTSD) and major depression have a higher risk of suicidal behavior. The research highlights the importance of assessing depressed patients for PTSD to determine accurate risk for suicide.
A study found that stress can alter fetal heart rates in response to a woman's emotional state, potentially impacting long-term health and development. The research suggests that high anxiety levels may shape fetal heart rate patterns even before birth.
A survey of 51 individuals handling human remains after the 1995 Oklahoma City bombing found minimal post-traumatic stress and depressive symptoms two years later. Factors such as social support, debriefing, and medical experience were linked to resilience in body handlers.
Scientists at Oregon Health & Science University have identified a potential target for anxiety-reducing drugs that may be less addictive and have fewer side effects. The research found that mice lacking a certain enzyme exhibit reduced anxiety levels, providing insight into the mechanisms of stress creation.
Researchers identified Kir6.2 as a protective mechanism against stress in the heart, which helps maintain equilibrium under peak workloads. The study found that mice lacking this protein experienced severe cardiac distress and died, while those with it survived stress tests.
A study published in Nature has identified a gene that protects certain brain and retinal neurons from oxidative stress, leading to neurodegeneration. The research, led by Dr. Susan Ackerman, found that mice with a mutation in the Aif gene experience severe oxidative stress, causing neuronal death.
A study of over 100 patients hospitalized for a heart attack found that repressive coping style can promote adjustment to traumatic stress in the short and long term. The repressive participants had lower rates of acute stress disorder and post-traumatic stress disorder compared to highly anxious participants.
Researchers found a common mutation in the DAT gene to be associated with trauma survivors who developed chronic PTSD, suggesting a genetic contribution to the disorder's development. The study implies that genetically determined variation in dopaminergic neurotransmission may play a role in shaping the pathological response to trauma.
A nationwide longitudinal study of psychological responses to September 11 found that six months after the attacks, effects continued throughout the country among individuals not directly affected. Those with preexisting mental or physical health difficulties and greater exposure to the attacks showed continued stress symptoms over time.
A nationwide study led by Roxane Cohen Silver found that individuals who disengaged from coping efforts after the 9-11 attacks were more likely to experience poor psychological outcomes. The study revealed that even those not directly affected by the attacks continued to experience anxiety about future terrorist attacks.
A group-based stress management training program has been found to lower blood glucose levels and improve health outcomes in people with type 2 diabetes. After one year, 32% of participants showed a reduction in hemoglobin A1C levels, while only 12% of those receiving no stress management training did so.
Researchers have identified HsfA1 as a master regulator of the tomato heat stress response, playing a crucial role in protecting plants from high temperatures. Transgenic tomatoes with over-expressed HsfA1 showed increased resistance to heat stress, while those deficient in HsfA1 were more susceptible.
Researchers found that acute stress symptoms were common among injured children and their parents, with nearly four-fifths experiencing at least one significant symptom. Pediatricians should support distressed parents to help them cope with traumatic injuries.
A study found that young black males and females retain sodium even after stress subsides, leading to prolonged elevated blood pressure and increased cardiovascular load. Researchers suggest this impaired natriuresis mechanism contributes to the development of essential hypertension in blacks.
A recent study found that cognitive behavior therapy (CBT) helps patients with panic disorder manage their symptoms without medication. Six months after stopping antidepressants, about 80% of patients who received CBT were symptom-free and experienced improved anxiety levels.
A new study found that Vietnam veterans with greater intellectual resources were significantly less likely to develop PTSD, and had less-severe symptoms if they did. The study suggests that verbal skills may help soldiers process their experience and establish social support networks.
Researchers found four mental health factors beyond depression that predict suicidal behavior in individuals with panic disorder, including overall anxiety level and fear of losing one's mind. The study suggests that these additional factors contribute to the development of suicidal thoughts, even when depression is present.
Researchers found that p53 and GR interact to balance cell survival and death in response to environmental stress. JIP1 protein is crucial for activating the JNK signaling pathway, which helps neurons respond to severe hypoxic stress.
A longitudinal study of Bosnian refugees found that those who experienced mass violence and torture continue to suffer from depression and posttraumatic stress disorder. The study highlights the importance of long-term mental health initiatives for recovery efforts, especially for elderly and disabled individuals.
A study found that women with coronary heart disease who experience severe marital stress are at a higher risk of recurrent cardiac events. In contrast, work stress did not predict new coronary events for working women. The authors suggest that specific preventive measures be tailored to the needs of women with CHD.
A new study reveals that one-fifth of young adult cancer survivors exhibit symptoms of posttraumatic stress disorder, a condition characterized by overwhelming anxiety and fear. The study found a four-fold increase in PTSD diagnosis among young adults compared to those aged 9-17.
A study conducted at Yale suggests that non-overweight women with abdominal fat have exaggerated responses to cortisol, a stress hormone. This leads to increased visceral fat, related to worse health outcomes like heart disease and diabetes.