A team of researchers from the University of Alberta has shown that betaretrovirus infects patients with primary biliary cirrhosis, a rare autoimmune liver disease. The study used next-generation sequencing to identify viral DNA integration sites in patient genomes, providing evidence of viral infection.
A recent study published in Nature Communications found that the brain can regulate fat metabolism, potentially stopping the development of atherosclerosis and its associated risks. The researchers discovered that the brain uses the presence of fatty acids to trigger the liver to reduce its own lipid production.
Researchers from UAlberta found that nighttime leg cramps peak in summer and burden doubles in the season. The study suggests that patients can stop taking quinine during colder months when symptoms worsen.
A recent study found that communities with higher levels of Indigenous language knowledge and cultural continuity have significantly lower diabetes rates, contrary to expectations. The research suggests that reconnecting Aboriginal Canadians to their cultural roots may be a crucial factor in addressing the epidemic of modern times.
Researchers at UCLA and J. Craig Venter Institute discovered a signaling interaction between TM7x and Actinomyces odontolyticus, which causes mucosal inflammation. The study sheds light on the biological importance of TM7x and its potential roles in chronic diseases.
A study of over 2,700 Australians found that many people with tooth loss do not need dentures as long as they have a sufficient number and type of remaining teeth. The researchers suggest allocating resources to prevent further tooth loss, diagnostic services, and follow-up care instead.
A significant increase in life-threatening heart infections has been identified, alongside a notable decrease in antibiotic prescriptions for dental patients. The study, published in The Lancet, reveals 35 extra cases per month in the UK and an 89% fall in prescribed antibiotics.
A new drug-based treatment may offer effective options for teenagers with neurofibromatosis type 2 (NF2), a devastating condition that affects 1 in 25,000 people worldwide. Researchers will investigate the mechanism of NF2 and explore how existing drugs can be repurposed to treat the condition.
A survey of UK veterinary students found that over 50% lacked confidence in discussing oral health with clients. To address this, a two-part special issue of the Journal of Feline Medicine and Surgery is dedicated to feline dentistry, featuring expert articles on examination techniques, periodontal disease, and anaesthetic protocols.
A new study from University of Alberta researcher Sunita Vohra examines the use of alternative therapies among pediatric cardiac patients in Canada. The study found that 64% of patients at Stollery Children's Hospital reported using complementary and alternative medicine products, with most having no regrets about their choices.
Researchers at the University of Alberta have explained how a key protein in the heart changes in heart failure, shedding light on the molecular mechanisms behind this complex condition. By studying troponin I, they discovered that increased calcium sensitivity actually helps trigger contraction, despite slower relaxation.
UTHealth researchers discovered that hollow-head toothbrushes harbor up to 3,000 times more bacteria than their solid-head counterparts. The study's findings highlight the importance of choosing a solid-head power toothbrush to minimize bacterial growth and prevent disease transmission.
A deck of cards created by UAlberta researcher Geoff Ball helps parents engage in discussions about their child's weight management. The CONversation Cards, recognized with a GEM award, aim to improve health outcomes and patient-centered care.
Research highlights the importance of glial cells in CNS regeneration. Glial cells provide support and protection for neurons, but also influence the survival and fates of transplanted neural stem cells. Regulating their behavior can create a permissive microenvironment for neuronal regeneration.
Researchers at the University of Adelaide found that acidity from soft drinks and fruit juice can cause lifelong damage to young people's teeth within 30 seconds. Parents are advised to limit their children's consumption of acidic beverages to prevent long-term dental issues.
The University of Maryland Schools of Dentistry and Medicine have received a five-year $10.7 million grant from the National Institutes of Health to study the causes, prevention, and treatment of sexually-transmitted diseases. The study aims to identify novel molecular biomarkers of susceptibility to STIs and disease severity.
Researchers at the University of Texas Health Science Center at San Antonio have discovered that capsazepine can shrink oral cancers while leaving healthy tissues intact. The study's findings suggest that capsazepine may reduce oral cancer pain by blocking tumor-secreted factors from stimulating pain-sensing neurons.
Researchers found that an enzyme thought to reside only in mitochondria can also produce acetyl-CoA in the nucleus, leading to faster cancer cell growth. The discovery may have broader implications for understanding epigenetic regulation in various physiological and pathological conditions.
Researchers confirm the role of Phox2b-expressing neurons in detecting and modulating CO2 levels. The study reveals a small region of the brain maintains homeostasis by detecting adequate CO2 levels, which may help prevent sudden death cases.
A Harvard-led team uses low-power laser therapy to stimulate human dental stem cells into forming dentin, a hard tissue similar to bone. The approach, led by David Mooney, could radically shift dental treatment and lead to broader clinical applications in regenerative medicine.
A research team led by Dr. Bing Hu aims to understand a cell defect that contributes to diseases like cancer and develop effective drug therapies.
Three NSU professors received patents for their innovative solutions: a novel cancer treatment called JFD that starves tumors, a surface modification technology for ceramic materials in dentistry, and a computer-based system to predict law school admissions. The patents demonstrate NSU's focus on developing novel products and services.
Researchers found that pharmacist-led interventions show a significant improvement in blood pressure and cholesterol levels compared to current standard of care. Nurse-led care saw a 30% improvement, while pharmacist-led care achieved a 43% improvement in improving patient outcomes.
Researchers at the University of Adelaide are investigating epigenetics as a tool for understanding oral health. They aim to develop personalized treatments by analyzing an individual's epigenetic profile and environment.
Researchers at Virginia Commonwealth University and MIT have identified a key enzyme necessary for a disease-causing bacterium to survive, which may lead to the development of new antibiotics. The study found that eliminating this enzyme or its manganese-attachment protein prevents the bacterium from causing heart valve disease.
Researchers from UCLA have developed a drug delivery system that may improve glaucoma management by reducing side effects and increasing patient compliance. The nanodiamond-drug compound was released into the eye through contact lenses, showing great promise for sustained treatment.
A 20-year retrospective study found that 85% of patients with chronic obstructive pulmonary disease (COPD) were overlooked by doctors, highlighting the need for improved early diagnosis and treatment. The study estimates that around 2.2 million people in the UK remain undiagnosed for COPD.
A University of Southern California study identifies a new population of mesenchymal stem cells in nerve and artery bundles that help maintain homeostasis. The discovery reveals that these stem cells are rich in the bundles, which contain nerves and blood vessels, and are regulated by the protein Shh.
A new study led by Meghan Azad found that probiotics have no effect on preventing childhood asthma. However, the research did identify a potential association between probiotics and lower respiratory infections in babies who received them as infants or in utero.
Medical researchers at the University of Alberta found that one chemotherapy drug prevents another from working, making combination therapy ineffective. This discovery will guide oncologists on how to combine or avoid certain drugs, ultimately leading to better treatment options for patients.
Researchers found that human periodontal ligament stem cells exhibit similar therapeutic effects to autologous Schwann cells in repairing peripheral nerve injuries. The study suggests a potential value for the use of human periodontal ligament stem cells in the repair of mental nerve injury.
Medical researchers at the University of Alberta have discovered a potential drug target for a rare genetic disease, paving the way for an alternative treatment. The discovery links specific defects in the enzyme to specific symptoms and could lead to the development of drugs to treat less severe forms of the disease.
A USC study has identified a cellular signaling pathway that converts healthy mesenchymal stem cells in the jaw into tumor cells, leading to benign but potentially harmful tumors. The researchers hope that this understanding can be used to develop target-specific treatments for these tumors.
Researchers at the University of Iowa have created a bio patch that can regrow bone by delivering DNA instructions to cells. The patch successfully regenerated bone in test animals and stimulated new growth in human bone marrow stromal cells. This breakthrough technology has potential uses in dentistry, including rebuilding bone for de...
Researchers at UAlberta have discovered a potential new treatment for colitis by using a leukemia drug to reverse symptoms in lab tests. The discovery suggests that inhibiting inflammation can reduce the likelihood of patients with ulcerative colitis developing colorectal cancer later in life.
A new study reveals that body mass index (BMI) is not an effective predictor of mortality in bariatric surgery patients. Researchers found that sex, smoking status, and diabetes are better indicators of risk. The study suggests that the current practice of prioritizing bariatric surgery for obese women may be misguided, as men who are ...
Researchers at UCLA School of Dentistry validated that pancreatic cancer biomarkers reside in saliva through a study on tumor-ridden mouse models. The team demonstrated that tumor-derived extracellular RNA molecules are transported through exosome vesicles and re-processed into saliva as biomarkers.
A team of UAlberta medical researchers has developed a potential new treatment for atrial fibrillation, a common heart rhythm problem affecting 1 in 200 people. The new drug, based on the resveratrol compound found in red wine and nuts, regulates electrical activity in the heart and reduces abnormal heart-rhythm episodes.
A new MRI technique has been developed to detect Fabry disease, a genetic condition that affects the heart, brain, and nerves. The T1 mapping test can identify microscopic changes in the heart muscle structure that are not visible on regular images, allowing for early detection and treatment.
Researchers at NYU College of Dentistry have discovered a new way HIV-1 reproduces itself without integrating its genetic material into cell DNA, allowing the virus to persist in vivo and evade antiviral drugs. This finding may lead to the development of new treatments aimed at eliminating the virus from infected individuals.
Nanodiamonds have been found to promote bone growth and deliver proteins to treat osteonecrosis, a debilitating disease that causes bones to break down. The tiny diamonds can be administered non-invasively, potentially revolutionizing dental implant procedures.
Medical scientists at the University of Alberta have made a key discovery about how the immune system kills healthy cells while attacking infections. Their research could lead to better solutions for cancer and anti-viral treatments by manipulating the immune system response to block collateral damage.
Scientists have discovered a new mechanism of DNA repair that operates differently from previously thought. The research reveals how proteins BRCA1 and TopBP1 communicate, which could lead to more targeted cancer therapies. Researchers aim to explore ways to exploit these findings for improved treatments.
The UCLA School of Dentistry is developing a salivary biomarker panel to detect stomach cancer using exRNA biomarkers. The research has the potential to create a new paradigm in salivary diagnostics, revealing saliva's transformative potential for detecting systemic diseases.
A new study by the Ostrow School of Dentistry of USC found that stem cells in gum tissue can relieve inflammatory diseases, including colitis. The cells, called gingival mesenchymal stem cells (GMSC), have the ability to become other cell types and affect the immune system.
The LSU Health Sciences Center New Orleans School of Dentistry has been awarded a $1.8 million grant to educate dental students about caring for HIV/AIDS patients and provide dental services to this population. Over 2,000 patients received dental care last year alone, with thousands more provided since the program's inception.
A clinical trial found that music significantly reduced children's reported pain and distress during IV procedures. The study also showed improved satisfaction levels for parents and healthcare providers. Researchers hope to continue exploring the benefits of music as a distraction from pain.
Researchers from the University of Alberta have developed a test to detect pathogenic E. coli in meat at food processing facilities, improving safety and reducing costs. The device is easy to use and can provide results in under an hour, making it an exciting application for the food industry.
Researchers from LSUHSC report that children sedated with meperidine and hydroxyzine experienced vomiting, prolonged sleep, and irritability, while those sedated with midazolam had fewer side effects. The study recommends educating parents on safe medication use and post-procedure care to improve child safety and comfort.
Research at the University of Alberta found that rats with low birth weights are more susceptible to age-related vision loss. The team's findings suggest a potential link between low birth weights and complex diseases like age-related eye disorders.
A new study found that the bacterium NI1060 causes gum disease by triggering a normally protective protein called Nod1 to destroy more bone, not just fight infection. This discovery could lead to personalized therapy for dental patients.
A new study found that consuming cheese and other dairy products can help protect teeth against cavities. The study showed that subjects who ate cheese experienced an increase in pH levels, which could be caused by increased saliva production and compounds in cheese adhering to tooth enamel.
Researchers at the University of Alberta have identified a genetic marker on chromosome 4 associated with sporadic breast cancer in Alberta women. The study, published in PLoS One, used DNA scans from over 7,200 women and found that those with sporadic breast cancer frequently carried this marker.
A study published in General Dentistry found that soda consumption, especially diet soda, can cause severe tooth erosion and damage similar to methamphetamine and crack cocaine use. The Academy of General Dentistry recommends minimizing soda intake and using sugar-free gum or rinsing with water after consumption.
Researchers at Plymouth University Peninsula Schools of Medicine and Dentistry have discovered how the loss of a tumour suppressing protein leads to abnormal cell division in the brain and nervous system. The study's findings may lead to new drug-based therapies to reduce or negate the need for multiple surgeries or radiotherapies.
Researchers from Case Western Reserve University found that emotional intelligence (EI) is a strong predictor of clinical performance in dental school. Students with high EI scores achieved better grades and demonstrated stronger communication skills in the clinic.
Research reveals ATRX mutations cause DNA damage leading to premature aging symptoms such as shortened lifespan, cataracts and low bone density. The study found mice without the ATRX gene displayed problems in learning and memory, body growth and metabolism.
Researchers from NYU College of Dentistry and School of Medicine will explore the role of intestinal microbiota in promoting pancreatic carcinogenesis. The study aims to determine whether endogenous gut bacteria can affect pancreatic oncogenesis and identify potential targets for prevention and treatment.
A Canadian study found that more than half of lower-back MRIs ordered at two hospitals were either inappropriate or of questionable value for patients. Family doctors were more likely to order these tests compared to specialists, highlighting the need for better education on when to use MRI scans.
A new study in Canada has found that over 40% of healthy individuals are taking daily aspirin to prevent cardiovascular disease, despite recent literature suggesting its limited benefits. The study's authors hope to raise awareness among physicians and patients about the importance of discussing anti-platelet medication use.