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Epigenetic signaling axis regulates proliferation and self-renewal of neural stem/progenitor cells

Researchers discovered a novel epigenetic signaling axis involving PRC1, microRNA, and PRC2 that regulates the self-renewal and proliferation of neural stem/progenitor cells. The study found that Ezh2 represses miR-203 expression, which negatively regulates self-renewal and proliferation but promotes neuronal differentiation.

SourceChinese Academy of Sciences Headquarters·JournalStem Cell Reports·DateJun 12, 2017

Large scale antibiotic resistant genes found in estuarine wetland due to human activity

A large-scale study detected high levels of antibiotic resistance genes in estuaries along China's coastline, with some samples containing up to 100 million genes per gram of sediment. The study suggests that human activity, particularly inadequate wastewater treatment, is the primary cause of this environmental pollution.

SourceChinese Academy of Sciences Headquarters·JournalNature Microbiology·DateFeb 9, 2017

CAS scientists discover BCAS2 involved in alternative mRNA splicing in spermatogonia and the transit to meiosis

Researchers from Chinese Academy of Sciences found that BCAS2 plays a crucial role in alternative mRNA splicing during mouse spermatogenesis, leading to impaired meiosis initiation. The study provides evidence for the importance of alternative splicing machinery in regulating germ cell development.

SourceChinese Academy of Sciences Headquarters·JournalNature Communications·DateJan 27, 2017

CAS researchers and Nobel Laureate develop new monomer fluorescent protein for SR imaging

CAS researchers have developed a new monomer fluorescent protein, Skylan-NS, enabling substantial improvements in the speed, duration, and noninvasiveness of live-cell superresolution microscopy. The protein shows high photostability, cycle numbers and signal-to-noise ratio, making it suitable for live-cell SR imaging.

SourceChinese Academy of Sciences Headquarters·JournalProceedings of the National Academy of Sciences·DateAug 26, 2016

New finding helps understand feeding ecology of Pleistocene proboscideans

A recent study using cutting-edge 3D dental microwear texture analysis reveals that Sinomastodon and Stegodon were obligate browsers of foliages, while Elephas had a broader diet of grasses and trees. This complex process suggests that biotic factors played a more substantial role in Pleistocene faunal turnovers than previously thought.

SourceChinese Academy of Sciences Headquarters·JournalQuaternary International·DateAug 3, 2016

Oldest actinopterygian from China provides new evidence for origin of ray-finned fishes

A newly discovered Chinese fossil, Meemannia, is the oldest known actinopterygian, providing new evidence for the origin of ray-finned fishes. The study reveals that early bony fish had 'cosmine'-like tissues, previously thought to unite lobe-fins and ray-fins, and confirms Meemannia as an early-diverging ray-finned fish.

SourceChinese Academy of Sciences Headquarters·JournalCurrent Biology·DateMay 19, 2016