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Hokkaido University


Mobile molecular robots swim in water

Researchers have created a microcrystal that utilizes self-continuous reciprocating motion for propulsion, enabling the microrobot to move itself sustainably in water. The microrobots exhibited different styles of propulsion and were affected by fin length, ratio, and elevation angle.

SourceHokkaido University·JournalSmall·TypeExperimental study·DateNov 28, 2021

Forests could be key to estuarine fish conservation

A study published in Conservation Biology found that forests surrounding rivers flowing into the sea increase the diversity of threatened fish species in Japan's estuaries. In contrast, waters surrounded by agricultural land show a decrease in fish populations.

SourceHokkaido University·JournalConservation Biology·TypeData/statistical analysis·DateNov 4, 2021

First evidence of microtubules’ mechanosensitive behavior

A research team led by Associate Professor Akira Kakugo of Hokkaido University has provided direct evidence that microtubules function as mechanosensors, slowing down kinesin movement when bent. This phenomenon is attributed to enhanced interaction energy between kinesin and deformed microtubule structural units.

SourceHokkaido University·JournalScience Advances·TypeExperimental study·DateOct 13, 2021

New nano particles suppress resistance to cancer immunotherapy

Scientists at Hokkaido University have developed a lipid nanoparticle that delivers immune-signaling molecules into liver macrophage cells to overcome resistance to anti-tumor immunotherapy. This approach has shown promise in mice experiments and could lead to the development of an adjuvant treatment for cancer patients.

SourceHokkaido University·JournalJournal for ImmunoTherapy of Cancer·TypeExperimental study·DateSep 17, 2021

Pyrrole chemistry: Good things come in threes

Researchers have successfully formed rings made of three pyrroles for the first time, which could be used to produce compounds with unique properties. The discovery explains why tripyrrolic macrocycles were not observed before due to strain issues.

SourceHokkaido University·JournalJournal of the American Chemical Society·TypeExperimental study·DateSep 16, 2021

Linking humans with blue carbon ecosystems

A study by Hokkaido University researchers found that seagrass ecosystems are more vulnerable to loss and degradation than mangrove ecosystems. Communities with greater reliance on fisheries and tourism income have higher socio-economic sensitivity due to low adaptive capacity, leading to limited alternatives to fishing. Improving acce...

SourceHokkaido University·JournalFrontiers in Marine Science·TypeSurvey·DateSep 3, 2021

Enabling safe delivery of RNA drugs to the lungs

Researchers at Hokkaido University created a lipid polymer that can carry genetic code into lung cells, potentially treating diseases such as acute respiratory distress syndrome and lung cancers. The delivery method bypasses the liver and targets specific lung cells without targeting ligands.

SourceHokkaido University·JournalMaterials Horizons·TypeExperimental study·DateJul 30, 2021

‘Double decoration’ enhances industrial catalyst

Researchers at Hokkaido University have designed a highly stable platinum-gallium catalyst that can support propylene production at very high temperatures, making it suitable for a month. The 'doubly decorated' catalyst is alloyed with lead and calcium, which blocks side reactions and improves stability.

SourceHokkaido University·JournalAngewandte Chemie International Edition·TypeExperimental study·DateJul 27, 2021

Underwater seismometer can hear how fast a glacier moves

A team of scientists from Hokkaido University used an ocean-bottom seismometer to detect continuous seismic radiation from a glacier sliding in Greenland. The study revealed that glacial basal motion can be monitored using underwater sensors, offering new opportunities for studying ice flow and calving processes.

SourceHokkaido University·JournalNature Communications·DateJul 1, 2021

Cross-generational consequences of lead poisoning

Researchers from Japan and Zambia have found a significant negative correlation between chronic lead poisoning in children and the health-related quality of life of their mothers. The study, which included 40 households in Kabwe, Zambia, showed that maternal vitality and mental health were particularly impacted by child lead exposure.

SourceHokkaido University·JournalChemosphere·DateJun 30, 2021

Hair follicles heal blisters at personal cost

Researchers discovered that hair follicle stem cells play a key role in healing skin blisters, which delays the growth of hair follicles in regenerated skin tissue. This balance between wound healing and development has implications for treating epidermolysis bullosa, pemphigoid diseases and other blistering conditions.

SourceHokkaido University·JournalEMBO Reports·DateJun 14, 2021

New method makes generic polymers luminescent

Researchers have successfully developed a new method to give luminescent properties to generic polymers like polystyrene and polyethylene. The technique makes it possible to easily prepare luminescent polymers without complicated organic synthetic methods.

SourceHokkaido University·JournalAngewandte Chemie International Edition·DateJun 10, 2021

Corals tell Arabian Sea story of global warming

Researchers found that global warming is causing changes to the Arabian Sea upwelling, which could impact commercial fishing, regional climate, and socioeconomics. The study used coral fossils to analyze seawater temperature and salinity changes over a 1,000-year period.

SourceHokkaido University·JournalGeophysical Research Letters·DateJun 4, 2021

Toward overcoming solubility issues in organic chemistry

A team of four scientists from Hokkaido University developed a rapid and efficient protocol for cross-coupling reactions using ball milling, expanding the pool of chemicals usable in organic synthesis. They successfully applied this method to mostly-insoluble aryl halides, yielding desired products.

SourceHokkaido University·JournalJournal of the American Chemical Society·DateMay 18, 2021

New therapy target for malignant melanomas in dogs

Scientists have discovered a potential new therapy target for canine cancer, specifically oral malignant melanoma in dogs. The treatment targets the PD-L1 molecule, which has shown promise in human cancer treatments, and significantly increased survival time for dogs with pulmonary metastatic OMM.

SourceHokkaido University·Journalnpj Precision Oncology·DateApr 22, 2021

Probiotics keep calves healthy, too!

Scientists at Hokkaido University developed a novel probiotic formulation to control severe diarrhea in calves, reducing mortality and economic loss. The probiotic supplement was tested on newborn calves and found to be effective in preventing bovine diarrhea caused by BRV and cryptosporidiosis.

SourceHokkaido University·JournalVeterinary Microbiology·DateApr 1, 2021

Urban squirrels, how much are we disturbing you?

Research finds that urban squirrels' success rates increase with repeated solving of a novel food-extraction task, suggesting adaptability to urban stressors. The study also reveals that direct human disturbance is a major stressor, while green coverage and squirrel population size have less impact on problem-solving performance.

The blast that shook the ionosphere

A high-velocity atmospheric wave was generated by Beirut's 2020 ammonium nitrate explosion, rivalling those from volcanic eruptions. The blast caused electron disturbances in Earth's upper atmosphere, including changes in total electron content in the ionosphere.

SourceHokkaido University·JournalScientific Reports·DateMar 16, 2021

Extreme UV laser shows generation of atmospheric pollutant

Researchers from Hokkaido University have found that ultraviolet light reacts with nitrophenol to produce atmospheric nitrous acid, a key component of photochemical smog. This decomposition process occurs in real-time and involves the distortion of the nitrophenol molecule's shape under extreme UV light.

SourceHokkaido University·JournalThe Journal of Physical Chemistry Letters·DateFeb 2, 2021

Gold nanoparticles more stable by putting rings on them

Researchers at Hokkaido University have developed a method to prevent gold nanoparticles from clumping, which could improve their effectiveness as anti-cancer therapy. Attaching ring-shaped synthetic compounds to gold nanoparticles retains their light-absorbing properties and maintains dispersion in solution.

SourceHokkaido University·JournalNature Communications·DateJan 21, 2021