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Indiana University


Argonaute protein slicing and retention of RNA fragments plays a role in the chemical modification of DNA for gene silencing

A team led by Dr. Feng Wang found that Argonaute 4 binds to and retains snippets of ribonucleic acid molecules guiding the chemical inactivation of genes with matching sequences, playing a crucial role in gene silencing through DNA methylation. The retained RNA fragments help tether AGO4-RNA complexes to corresponding DNA sequences, bo...

SourceIndiana University·JournalGenes & Development·TypeObservational study·DateFeb 6, 2023

Silicon nanochip could treat traumatic muscle loss

Researchers at Indiana University School of Medicine developed a minimally invasive nanochip device that can reprogram tissue function by delivering specific genes. The technology has shown promise as a treatment for traumatic muscle loss, with improved muscle function observed in rats following volumetric muscle loss.

SourceIndiana University·Journalnpj Regenerative Medicine·TypeExperimental study·DateNov 9, 2022

Evolution of tree roots may have driven mass extinctions

A study led by Gabriel Filippelli suggests that the evolution of tree roots during the Devonian Period caused massive algae growth, depleting ocean oxygen and triggering mass extinctions. The researchers found that tree roots released excess nutrients into the oceans during times of decay, leading to catastrophic events.

SourceIndiana University·TypeExperimental study·DateNov 9, 2022

Stain-resistant school uniforms could expose children to harmful chemicals

Millions of schoolchildren in the US and Canada are exposed to potentially harmful levels of per- and polyfluoroalkyl substances (PFAS) through stain-resistant school uniforms. The study found concentrations as high as those in outdoor clothing, posing health risks such as cancer and severe COVID-19 outcomes.

SourceIndiana University·JournalEnvironmental Science & Technology·TypeData/statistical analysis·DateSep 21, 2022

Crop disruption from war in Ukraine could increase global carbon emissions, food prices

A new study predicts that the disruption of crop production in Ukraine due to the Russian invasion will lead to increased global carbon emissions and food prices. However, other countries are stepping up their production to compensate for the loss, which may alleviate food insecurity but with significant environmental impacts.

SourceIndiana University·JournalNature Food·TypeComputational simulation/modeling·DateSep 19, 2022

High school students with disabilities achieve better outcomes in inclusive academic settings

A recent study by Indiana University researchers found that high school students with disabilities who spend 80% of their time in general education classrooms score higher on state reading and math assessments. This is the second phase of a previous study that showed similar results for younger students with disabilities, highlighting ...

SourceIndiana University·JournalThe Journal of Special Education·DateSep 15, 2022

Reaching national electric vehicle goal unlikely by 2030 without lower prices, better policy

A new study from Indiana University warns that the US is unlikely to reach its national goal of 50% plug-in electric vehicle penetration by 2030 unless electric vehicles become more affordable. The study suggests that lower prices and better policy are needed to stimulate consumer demand for affordable electric vehicles.

SourceIndiana University·JournalFrontiers in Environmental Science·TypeComputational simulation/modeling·DateSep 13, 2022

Hiding chocolate stashes or Amazon purchases from a partner? ‘Guilty’ purchases may have benefits

Research finds that feelings of guilt from keeping everyday consumer behaviors a secret can lead to greater relationship investment. Participants reported engaging in mundane secrets like sneaking pizza or watching ahead on a TV show, which drove them to invest more in their relationships.

SourceIndiana University·JournalJournal of Consumer Psychology·TypeObservational study·DateAug 24, 2022

Fast, efficient COVID-19 biosensor under development

Researchers from Indiana University are developing a new biosensor that can analyze samples from 96 individuals in under three hours, with a sensitivity rate of 100% and specificity rate of 90%. The sensor detects not only the virus's spike protein but also the proteins created by the body to protect against the virus.

SourceIndiana University·JournalACS Applied Materials & Interfaces·DateJul 21, 2022

Physicists work to shrink microchips with first one-dimensional helium model system

Researchers at Indiana University and the University of Tennessee have developed a one-dimensional helium model system, which enables the creation of smaller and faster microchips. The new system is designed to explore the behavior of particles in a confined space, allowing for the study of previously unexplored physics.

SourceIndiana University·JournalNature Communications·TypeExperimental study·DateJul 6, 2022

New insights on infant word learning reported in study

A new study published in the Proceedings of the National Academy of Sciences offers fresh insights into infant word learning. Researchers found that infants between 7 and 11 months old learn words by building up memory representations over time, rather than through repeated connections between words and objects.

SourceIndiana University·JournalProceedings of the National Academy of Sciences·DateJun 7, 2022

End of strict COVID measures in China could result in 1.5 million deaths, study finds

A recent study published in Nature Medicine predicts that China's abandonment of Zero-COVID policies could result in approximately 1.5 million deaths due to the highly contagious omicron variant of COVID-19. The study highlights the need for critical measures such as vaccination, antiviral therapies, and non-pharmaceutical intervention...

SourceIndiana University·JournalNature Medicine·TypeData/statistical analysis·DateJun 2, 2022

Research: Partnership between humanitarian organizations and governments is essential for providing cash assistance to refugees

Research from Indiana University reveals that cash assistance is a double-edged sword, harming both refugees and local residents if not implemented correctly. Humanitarian organizations can extend cash assistance to host regions with market power by partnering with local governments.

SourceIndiana University·JournalManufacturing & Service Operations Management·TypeData/statistical analysis·DateMar 22, 2022

Professor’s M-Score model remains most viable means of predicting corporate fraud

A new study co-authored by Indiana University professor M. Daniel Beneish finds that the M-Score model is still the most economically viable means of predicting corporate fraud. The model's success rate has been doubled, but at a higher cost of false positives, making it less practical for auditors to use in practice.

SourceIndiana University·JournalThe Accounting Review·TypeData/statistical analysis·DateFeb 17, 2022

Early childhood exposure to lead in drinking water associated with increased teen delinquency risk

A new study by Indiana University researchers found that children exposed to lead in drinking water before age 6 have a higher risk of being reported for delinquency after age 14. The study highlights the need for recognition of risks to children relying on private well water and access to clean drinking water.

SourceIndiana University·JournalProceedings of the National Academy of Sciences·DateFeb 1, 2022