A new study predicts train-induced environmental vibration using physics-based numerical simulations and limited field data, outperforming conventional models. The method improves existing workflows, reducing dependence on expensive field measurements.
Researchers used CRISPR/Cas9 to create rice mutants with increased oleic acid content and decreased linoleic acid levels. The study demonstrates a novel strategy for designing functional rice cultivars with improved nutritional value and stable agronomic traits.
A new study uses large language models and network analysis to quantify investor emotions' fragility. High emotional vulnerability is linked to unstable stock prices and lower returns.
A team from Chongqing Medical University developed a model that integrates sMRI and fMRI data to predict treatment responders, achieving high accuracy rates. The dual-branch graph attention network (DBGAN) captures coordinated brain changes linked to emotion regulation and memory processing.
A novel deep learning model, LA-TextCNN-BiLSTM, has been developed to improve the accuracy of automatic disease classification using ICD-11 for Chinese Electronic Medical Records (EMRs). The model achieved an 83.86% accuracy rate and demonstrated robust performance in multi-label classification.
A new spray-applied polyurea-based nanocomposite sensing coating integrates covalently functionalized graphene nanoplatelets into a two-component polyurea matrix. This enhances processability, weatherability, and establishes a robust conductive network for reliable resistive sensing.
A team of researchers has developed a method for preparing supramolecular prodrug assemblies to enhance chemodynamic therapy efficacy by consuming glutathione (GSH) and inhibiting its synthesis. The approach allows for the simultaneous release of dual functional molecules from self-assemblies, amplifying cellular oxidative stress.
Scientists have created a high-performance cathode material for aqueous zinc-ion batteries by converting a layered MXene into an amorphous form. The new material, a-V₂CT_x, shows remarkable improvements in capacity, charging speed, and durability.
A forecasting study found that the Inflation Reduction Act will save approximately $400 million on Louisiana Medicare diabetes drug costs over five years. Patients are expected to switch from non-negotiated to negotiated drugs due to lower costs, resulting in significant savings.
A retrospective insurance claims analysis found a high prevalence of polypharmacy among children under 15 in Côte d'Ivoire, with regional disparities evident. The study highlights the need for targeted interventions to reduce polypharmacy risks and costs across all regions.
A study applies a multi-criteria decision analysis framework to evaluate three orphan medicinal products, laronidase, emicizumab, and dimethyl fumarate, with highly consistent quantitative scores. The framework offers a transparent and multi-faceted approach to evaluating high-impact drugs for rare diseases within reimbursement systems.
Researchers discovered that nicotinic acid can dramatically reduce liver damage caused by ischemia-reperfusion injury. The compound targets damaged mitochondria, reducing markers of liver injury, suppressing inflammation, and promoting mitophagy and mitochondrial biogenesis.
This study showcases the potential of MOF–NP composites to accelerate key nitrogen electrochemical reactions under mild conditions. The analysis highlights how these hybrid materials improve reaction selectivity, stabilize intermediates, increase Faradaic efficiency, and support strong long-term durability.
Lattice-anchored iridium enhances metal-oxygen covalency and preserves structural integrity under harsh acidic conditions, while Ir at surface hollow sites degrades cobalt and oxygen migration. Long-term tests show improved stability for lattice-anchored iridium OER catalysts.
Researchers developed a methylurea-assisted electrolyte that forms a robust solid electrolyte interphase directly on the zinc surface, dramatically improving zinc reversibility. This engineered SEI enables long-life anode-free zinc batteries with unprecedented cycling life and exceptional durability.
Researchers developed a kinetic activation strategy to regulate in-plane transition-metal ion migration and trigger controlled local structural rearrangements. This approach enabled reversible lithium storage beyond the long-standing 1.1 stoichiometric limit, reaching 348 mAh g⁻¹.
Researchers from Nankai University developed a breakthrough strategy to prevent voltage decay in lithium-rich layered oxides by using trace dopants placed at tetrahedral sites, suppressing both in-plane and out-of-plane TM migration. The study demonstrates a new atomic-scale stabilization mechanism for over 250 cycles.
Researchers develop copper-modified cobalt oxyhydroxide catalyst for clean glucose oxidation, achieving high formate yield and reducing energy input. The membrane-free system delivers over 500 μmol h⁻¹ cm⁻² of hydrogen, offering a scalable and economically competitive route to green hydrogen.
Researchers found that combining LiDFOB and LiPF₆ in a dual-salt electrolyte regulates electrode interfaces, forming a double-layer cathode electrolyte interphase and a LiF-rich solid electrolyte interphase. This design lowers interfacial impedance, promotes uniform Li deposition, and enhances durability under cycling.
Researchers discovered that electrowetting increases active surface area and restructuring the electric double layer, leading to enhanced charge storage. Mesopores combined with multivalent ions support stronger ion packing and dual-ion adsorption, delivering higher capacitance.
In situ EC-SERS captures fingerprint vibrational signals of trace and transient interfacial species under operational conditions. This technique reveals how electrocatalyst properties and interfacial environments govern fuel cell, water electrolysis, and CO2RR related reactions.
A systematic review of randomized controlled trials evaluating large language models in digestive diseases found only 14 eligible studies worldwide. Most focused on gastrointestinal and hepatobiliary diseases, with clinical decision-making and patient education being common applications. The authors emphasize the need for high-quality ...
Professor Lim Siong Guan shares insights on how to navigate uncertainty in a rapidly changing world by emphasizing the importance of governance, leadership development, and institutional culture. He stresses the need for proactive planning, trust-building, and adaptability in response to unexpected events.
The Qinghai-Tibet plateau faces multiple conservation challenges due to climate change and human activity. Research reveals shifting plant diversity under these pressures, with critical gaps in understanding the mechanisms behind acclimation and adaptation. Future research prioritization is proposed to address conservation concerns.
A study by Chongqing University of Posts and Telecommunications proposes a modality fusion strategy to enhance visualization-inertial trajectory localization. The approach leverages attention mechanisms and cross-modal communication, achieving robust accuracy in complex environments.
Polysaccharide-based microneedles have been shown to effectively deliver anti-cancer agents directly into the skin, targeting rich networks of immune cells. The microneedle matrix itself can also modulate these immune cells, creating a powerful dual-action therapy.
Research finds cancer cachexia-related immune cells impair T-cell negative selection, leading to irAEs. This study establishes a critical mechanism connecting cancer cachexia and irAEs, opening new avenues for targeted interventions.
Researchers reviewed magnetic materials preparation, structural design and actuation systems for medical applications, highlighting potential in targeted drug delivery, minimally invasive surgery and disease diagnosis. Despite challenges, the authors emphasize magnetic soft robots' potential to reshape future healthcare practices.
Researchers developed a magnetic nanocomposite that combines magnetic heating properties with bioactivity to treat bone cancer and support new bone growth. The material promotes tissue regeneration while selectively destroying cancer cells under an alternating magnetic field.
A fiber neural network, proposed by Tsinghua University, processes information entirely within the optical domain, reducing latency and power consumption. The system achieved 100% classification accuracy in modulation format recognition and demonstrated robustness against noise, paving the way for real-world deployment.
A new study identifies the TaJAZ1 gene as a key regulator of starch biosynthesis in wheat, leading to increased yields and resistant starch content. The findings offer a genetic strategy for creating wheat varieties that balance productivity and nutritional quality, benefiting food security and metabolic health.
A comprehensive review of ultrasonic measurements assesses cement bond quality in wells. Recent advances include high-resolution insight into casing-cement interfaces using pulse-echo and pitch-catch techniques.
A new study introduces a 'theragnostic' agent that combines therapy and diagnosis for ischemic stroke. The engineered extracellular vesicles demonstrate dual capability of dynamic monitoring and synergistic therapy, tracking restoration of vascular integrity and reducing infarction volume.
A new study reveals that algorithmic control's three-dimensional functions exert significantly different impacts on gig workers' turnover intention. Behavioral constraints and tracking evaluation exacerbate relative deprivation, while standardized guidance mitigates this effect, directly reducing turnover intention.
Researchers use CRISPR/Cas9 to edit the mstnb gene in grass carp, resulting in denser muscle tissue with a higher number of fibers. This breakthrough allows for targeted and precise changes in muscle growth, promising improvements in aquaculture.
New review article highlights advancements in VLMs, enabling unified, intelligent approach to complex images. Key milestones include Vision Transformer and CLIP, bridging visual understanding and language generation.
Researchers create a new type of silicone elastomer with ultra-softness, ultra-stretchability, and high toughness. The material is designed to be 'burden-free' for on-skin wearables, offering excellent mechanical integrity and electronic reliability. It also exhibits excellent UV blocking properties and can block 97.9% of incident light.
Researchers developed a 'one-pot' CRISPR-Cas12i3/Cas13d-based assay to detect ASFV genotypes I and II with high sensitivity and specificity. The assay achieved 100% diagnostic sensitivity and specificity, outperforming traditional real-time PCR methods.
A study found that Streptococcus suis serotype 2 collagenase-like protease enhances virulence and tissue colonization, promoting BBB destruction and increased permeability. The protein also induced apoptosis in brain microvascular endothelial cells and infiltrated immune cells into the brain after infection.
A new system, Coded Aperture Compressive Temporal Imaging (CACTI), uses AI to overcome traditional limitations in high-speed photography. The system achieves exceptional image quality while reducing data requirements, making it useful for studying transient physical processes.
Researchers develop a cohesive framework for designing high-performance flexible vdW electronic and optoelectronic systems, exploiting strain engineering to tune physical properties. The approach enables devices with improved mobility, sensitivity, and functionality, including sensing, memory, and computation capabilities.
Researchers discovered high concentrations of Benzothiazoles in outdoor airport PM10, indicating significant input from airport activities. The findings suggest specific chemical markers for tracing airport non-exhaust emissions into the air.
Researchers found that nanoplastics entered the bloodstream and accumulated in organs within days of ingestion, potentially leading to disorders in nervous and reproductive systems. The particles were primarily expelled through the intestine, but some remained trapped for a long time.
A study published in The Journal of Finance and Data Science shows that integrating credit and debit data enhances the ability to predict credit card delinquency. By analyzing transaction patterns, the model identifies distinct behavioral segments with different risk profiles.
A research team at Foshan University has developed a method to reduce cadmium accumulation in rice crops using foliar-applied molybdenum nanoparticles. The study shows that MoNPs down-regulate key genes involved in cadmium uptake and cell wall modification, reducing Cd accumulation in root tissues and limiting its entry into grains.
The journal prioritizes research on emerging contaminants, water-carbon-nutrient interplay, and advanced modeling technologies to inform policy and optimize multi-objective management strategies. The new leadership aims to steer the field toward a more sustainable and resilient future for our planet's essential water systems.
The study reveals that GPI-anchored proteins shield chitin from host immune recognition, compromising cell wall integrity and reducing virulence. Deleting ChGPI7 or treating with hydro fluoric acid eliminates these proteins, exposing chitin and disrupting infection structures.
Researchers have assembled mitogenomes from various sugarcane species, revealing diverse configurations and phylogenetic implications. The analysis identified multiple potential conformations and RNA editing sites in the protein-coding genes, providing insights into the genetic diversity of the Saccharum complex.
A team of researchers analyzed the chemical structures of Acinetobacter baumannii's capsular polysaccharides and lipopolysaccharides, revealing over 200 distinct types of sugars. These sugars are promising targets for new therapies, including glycoconjugate vaccines that can trigger a strong immune response.
Researchers have successfully induced sexual reversal in all-female mandarin fish using functionalized Single-Walled Carbon Nanotubes as a delivery vehicle. Key genes amh and amhy were introduced into juvenile fish through an immersion bath, leading to detectable gene expression in the gonads.