A Rice University undergraduate student and her mentor have synthesized the first molecule found in poppies, setigerumine I, using a three-step process at room temperature. The environmentally friendly method produced 20 milligrams of the rare extract, which could be a potential precursor for non-addictive painkillers.
Researchers at Rice University have discovered a new mechanism by which prions can regulate protein synthesis in cells. The model proposes that prion aggregates and their monomers play a role in channeling RNA messages into new proteins, forming organized protein synthesis factories. This discovery has implications for our understandin...
Researchers at Rice University developed a method to decontaminate disposable surgical masks by heating them to 70 degrees Celsius, eliminating 99.9% of the SARS-CoV-2 virus and preserving mask material. The study provides promise for adapting this protocol to future outbreaks.
Borophene, a 2D version of boron, can be synthesized on hexagonal boron nitride using weak van der Waals forces. This method allows for easier removal and evaluation of the material for its plasmonic and photonic properties, as well as its electronic properties relevant to superconductivity.
Rice scientists developed a comprehensive approach to building better base editors, molecular machines that target and fix faulty DNA at single-base resolution. Their new strategy combines theory and experimentation to pinpoint binding energies and characterize deaminase interactions with ssDNA.
Researchers at Rice University are creating a 3D-printed smart helmet with embedded sensors to protect soldiers' brains against kinetic or directed-energy effects. The program aims to modernize standard-issue military helmets by incorporating advances in materials, image processing, artificial intelligence, and energy storage.
Researchers developed a new online portal, DINC-COVID, to speed up the identification of potential pandemic treatments. The platform incorporates models of three drug targets and uses ensemble docking to score ligands' success in binding.
Rice University researchers have developed a method to control the growth of tetrahedron-shaped nanoparticles, which can be used as building blocks for unique metamaterials. The team discovered that balancing thermodynamic and kinetic forces during crystallization allows for symmetry breaking, forming pyramid-shaped nanocrystals.
Researchers created a sulfur-selenium alloy that outperforms traditional coatings in protecting steel from corrosion and oxidation. The material's self-healing properties allow it to recover from scratches and damage, making it suitable for infrastructure applications.
Rice University's Neuroengineering Initiative is working on developing noninvasive systems to monitor and control the brain. Jerzy Szablowski aims to achieve single-cell precision in 15-20 years through innovative receptor development and gene therapy.
Rice materials scientists develop a method to print arbitrary 3D shapes, creating micro-scale electronic, mechanical and photonic devices. The process involves two-photon polymerization and doping with rare earth salts for photoluminescent properties.
New research from Rice University finds that working single mothers who feel in control of their schedules are more likely to engage in healthy behaviors during their downtime. A present-focused mindset also helps them maintain a sense of control as demands on their time increase.
Rice chemist Julian West and graduate student Yen-Chu Lu discovered manganese as a more efficient catalyst for synthesizing fluoroketones, precursor molecules for drugs. The use of manganese reduces material costs and simplifies purification.
A new process recovers rhodium, palladium, gold and silver from electronic waste in seconds, producing a byproduct clean enough for agricultural land. The flash Joule heating method uses significantly less energy than traditional lab methods, making it an environmentally friendly alternative.
The Army has pledged $5.2 million to Rice University's research on flash Joule heating, a process that turns waste into graphene and other valuable materials. The technology can recover precious metals from electronic waste and toxic metals from contaminated soil.
Researchers at Rice University and the US Army are developing a portable skullcap that analyzes cerebrospinal fluid flow during sleep to clear metabolic waste. The goal is to noninvasively measure and modulate brain health in soldiers, potentially treating sleep disorders in real time.
The NSF-backed project, I-ACED, integrates internships and research experiences to prepare students for careers in engineering. The grant will support 220 students from low-income backgrounds seeking master's degrees in STEM disciplines.
The NSF has renewed the Physics of Living Systems graduate research network at Rice for five years, connecting students and educators across institutions to share resources and data. The award will fund local expenses and training programs, as well as efforts to grow faculty and student numbers in the field.
Researchers at Rice University have made a groundbreaking discovery about the reproductive habits of dinoflagellate algae, which can help coral reefs adapt to climate change. By studying sex in these tiny creatures, scientists hope to breed strains that are more tolerant of environmental stress.
Bioengineer Kevin McHugh is developing a platform to improve the performance of injectable drugs, which often release diminishing amounts of medication over time. The goal is to create predictable, long-lasting delivery systems for better patient outcomes and reduced dosing frequency.
Researchers at Rice University have been awarded a four-year, $1.2 million National Institutes of Health grant to advance the art and science of creating custom-designed microbial colonies. The grant will enable the development of technologies like synthetic tissues that enhance soils or gut microbiomes.
Researchers at Rice University have refined models to analyze gadolinium-based contrast agents, which are used in 40% of MRIs worldwide. The team's goal is to design better and more customizable contrast agents that improve image quality while minimizing risks.
Researchers investigate light smashups to create new physics beyond the Standard Model, building on previous discoveries that matter can be generated from light. The study reveals implications for understanding primordial plasma and the strong force.
A Rice University professor has received a $2.4 million grant from the NIH to develop open-source software for designing personalized treatments for movement impairments using computational modeling and simulation. The software will create customized computer models of individual patients, optimizing treatment solutions.
Researchers have found that certain peptides can target the internal mechanisms of bacteria, making them effective against antibiotic-resistant microbes. The study suggests that these peptides could be used to design therapeutic agents that succeed where standard antibiotics fail.
Researchers discovered that amyloid beta peptides, which form gummy plaques in Alzheimer's disease, go through several intermediate stages of frustration as they dock and lock to growing fibrils. This suggests that drugs might be developed to stabilize the fibril tips and block further aggregation by targeting the 'Achilles' heel' of f...
The university will acquire an optical tweezer to study colloidal copolymer chains, protein binding strength and other phenomena. The instrument will be made available to Rice researchers and collaborators.
Researchers are using tree rings and sediments to reconstruct Atlantic hurricane history over millennia. By combining these natural archives with global climate model simulations, they aim to refine the record of history's hurricanes.
The Welch Institute has appointed Matthew Tirrell, a renowned material scientist, to chair its Scientific Advisory Board. His expertise in nanotechnology and biomolecular engineering will help the institute accelerate discovery and innovation in advanced materials.
Researchers found that spin-orbit coupling induces asymmetric interactions between electrons in chromium triiodide, affecting its topological excitations. This discovery could exist in other 2D van der Waals magnets and has implications for spintronics.
A Rice University lab developed a 'smart' shirt that gathers accurate EKGs and heart rates using conductive nanotube thread. The fibers, just as conductive as metal wires but washable and comfortable, provided better data than standard chest-strap monitors.
Yang Gao's lab has received a $1.9 million NIH grant to investigate the mechanisms of proteins that produce copies of genomic DNA, with potential implications for cancer treatment. The research aims to understand how DNA replication and repair processes can be targeted to develop new therapies.
Researchers have discovered a room-temperature transition between 1D and 2D electrical conduction states in topological crystals of bismuth and iodine. The material's electronic behavior changes at a transition temperature around 80 degrees Fahrenheit.
Isaac Hilton is using non-integrating episomal DNA viruses to create a new platform technology for cell and gene therapies. He aims to hijack these viruses to safely program medicinal functions in human cells.
The center will provide a one-stop shop for custom DNA constructs, accelerating cancer research through access to state-of-the-art tools. The facility will enable transformative, large-scale experimental projects that were previously impossible for individual labs.
Researchers at Rice and Baylor are expanding their efforts to halt bone cancer metastasis using a molecule targeting osteoporosis and HER2 protein. Their goal is to improve drug concentration at tumor sites, inhibit secondary metastasis, and explore the therapeutic effect mechanism.
A Rice University study finds that teams benefit from diverse emotional states, with 'negative affect' promoting critical thinking and 'positive affect' fostering broad thinking. This 'dual-tuning' leads to greater team creativity.
Researchers have developed a new material that can convert heat into energy, with potential applications in textiles and electronics. The woven nanotube fibers show promise as building blocks for fiber and textile electronics, and could also be used to cool sensitive electronics.
Researchers at Rice University found that cool stars have dynamic surface behaviors influencing their magnetic environments and planetary habitability. This study suggests that small stars share similar properties with the sun, enabling predictions for exoplanet conditions.
A new study from Rice University finds that middle-class people who made plans to stay in their neighborhoods before flooding are less likely to relocate even if they suffered significant damage. Long-term planning and social pressure played a key role in residents' decisions to stay or leave flooded homes.
Researchers at Rice University are developing novel computational approaches to track environmental microbiome dynamics over time, across species and after perturbations. The team will use biofilm-based 'species abundance networks' on scaffolds to observe how they form their own genome-exchange networks.
Pasquali proposes splitting hydrocarbons to produce clean hydrogen energy and solid carbon materials, which could replace materials with large carbon footprints. This transition would generate robust growth in manufacturing jobs and improve production efficiency.
The Center for Adapting Flaws into Features will explore chemical defects to optimize material properties, with a focus on creating better catalysts and electronics. The team aims to develop new approaches towards transformative technologies by leveraging advanced microscopy, spectroscopy, and data science.
Researchers at Rice University have developed a model of how internal states and external stimuli shape the behavior of hydra, a tiny, jellyfish-like creature. By studying their neural networks, scientists can gain insights into fundamental principles that may apply to more complex animals.
Rice University bioengineers are developing an insulin-producing implant to regulate blood glucose levels in Type 1 diabetics. The implant uses human stem cells and 3D printing to mimic the natural behavior of the pancreas, with the goal of achieving consistent target blood glucose levels.
Rice University and Baylor College of Medicine researchers have developed a new model for studying intestinal infections, using custom hydrogel-based platforms. The study found that softer hydrogels promote bacterial adhesion to epithelial cells, which is crucial for understanding the dynamics of infectious diseases.
Luay Nakhleh's team will use single-cell DNA data from the University of Texas MD Anderson Cancer Center to identify mutations at the root of the disease and how they evolve in tumors. By building open-source models and tools, they aim to refine cancer treatments and predict patient outcomes.
Researchers at Rice University have created a coating made of soft polymer that can help keep knotty ceramic structures from shattering. The coating was tested on complex lattices called schwarzites, which were found to be up to 4.5 times more resistant to catastrophic fractures.
Rice University scientists have isolated a biocatalyst that controls the chirality of compounds, enabling more accurate drug synthesis. The discovery could lead to improved pharmaceutical production by providing a new tool for controlling stereochemistry.
Julian West's lab receives a five-year, $1.8 million NIH grant to simplify the synthesis of organic chemicals, enabling new hydrogen atom transfer modules and 'mutase-like' catalysis. This will accelerate the development of new drugs and compounds with improved properties.