Researchers at Ruhr-University Bochum discovered that kainate receptors affect the development of brain cells immediately after birth, causing increased activity and dendrite growth. The discovery sheds light on the role of glutamate receptors in early maturation of nerve cells.
Researchers have developed a new efficient catalyst to synthesise aromatic amines, which are central building blocks in many drugs and pesticides. The system is more active than conventional catalysts, enabling faster and more efficient production of these compounds.
A team of researchers has identified a mechanism regulating the regeneration of neural pathway insulation. The discovery highlights the significance of the Vav3 exchange factor in controlling molecular switches that activate and deactivate signaling processes.
Researchers at Ruhr-University Bochum discovered that water fleas detect predator presence through a cocktail of signalling molecules secreted by Chaoborus larvae during digestion. The fleas respond by growing defensive features such as neckteeth and spines, making them harder to consume.
Researchers at Ruhr-Universität Bochum have identified a small RNA molecule that significantly affects antibiotic resistance in soil bacteria. Without this molecule, the bacteria are more sensitive to penicillins and produce less of the enzyme degrading these antibiotics.
Researchers at Ruhr-University Bochum used microscopic methods to observe the solvation process of a crystal in water. The team imaged individual molecules at extremely low temperatures, revealing the attachment of solvent molecules and the loss of molecular order.
Researchers from Ruhr-University Bochum have developed a new catalyst using mineral pentlandite to convert carbon dioxide into valuable source materials. The catalyst's stability and ability to produce synthetic gas mixtures make it a promising approach to combat climate change.
Researchers from Ruhr-University Bochum developed a system combining gas diffusion electrode technology with the enzyme hydrogenase to achieve significantly higher current densities. The resulting biofuel cell achieved a power density of up to 3.6 milliwatts per square centimeter and an open circuit voltage of 1.13 volts.
Researchers at Ruhr-University Bochum developed a new fabrication process for transparent ultra-thin silver films, which may improve the efficiency of solar cells and light-emitting diodes. The process overcomes challenges associated with traditional chemical methods.
Researchers at Ruhr-University Bochum have identified the proton transfer pathway in [FeFe]-hydrogenases, a crucial step for efficient hydrogen production. The study reveals that amino acids with no function can shut down hydrogenase activity, and provides valuable insights into the molecular mechanism of proton transfer.
A team of researchers has successfully replicated the internal channel structures of natural enzymes in metallic nanoparticles, resulting in three times greater catalytic activity. The study focused on the oxygen reduction reaction and found that active centers within the channels enhanced reaction efficiency.
A study published in Communications Biology found that changing an enzyme's surface density can alter its ability to bind different substrates. By swapping single components on the surface, researchers were able to convert one enzyme into another, with implications for biotechnology applications.
Biopsychologists demonstrate that subtle timing differences in the right hemisphere allow it to control specific functions, while the left hemisphere delays its activity. The study reveals a sophisticated mechanism underlying hemispheric dominance.
The hepatitis B virus is highly stable at room temperature and can withstand temperatures of four degrees centigrade for nine months. Disinfectants are effective against the virus when applied undiluted, but their effectiveness decreases with dilution.
Researchers from Ruhr-Universität Bochum found that people's lateral preferences for kissing and hugging are influenced by both handedness and emotional context. In emotional situations, the preference shifts towards the right side of the body.
Biophysicists at Ruhr-University Bochum developed a Raman microscopy method to detect cancer drug resistance in tumour cells. The new approach shows effectiveness in non-mutated cells but remains ineffective in mutated cells, similar to clinical observations.
Researchers identified new biomarkers that can detect glaucoma at an early stage, enabling early intervention. The study's findings suggest that these biomarkers may inhibit neurodegeneration in the optic nerve and retina.
A study investigated ideal access control rules for smart home devices in networked households, analyzing user preferences and derived suggestions for access management. The researchers found that contextual factors such as age, location, and usage history affect access rights, suggesting a need for customizable settings.
A team of researchers has discovered a noble metal-free catalyst system that is as active as platinum, thanks to the high entropy effect. The alloy, made up of five elements, forms new active centers that offer entirely new properties and are relevant for catalysis.
Research reveals a single missing gene in mothers leads to miscarriages due to placenta problems, including fewer blood vessels and altered shape. The study provides new insights into recurrent miscarriage in humans and lays the foundation for further research on placenta development.
Researchers have discovered that brain oscillations can be used to measure the activity of grid cells, which form the brain's navigation system. This breakthrough may lead to earlier diagnosis and treatment of Alzheimer's disease by testing impaired functionality.
Scientists have gained new insights into dynamic structural changes in light-sensitive biomolecules, revealing a universal mechanism for the transformation from dark-adapted to light-adapted states. This discovery could advance applications in agriculture and optogenetics.
Researchers found that brain activity patterns during sleep can reveal which memories are stored and which forgotten. The brain reactivates memory traces during certain sleep phases, especially when gamma band activity from deep processing is reactivated during ripples in the hippocampus, leading to later recall of images.
Researchers at Ruhr-Universität Bochum have gained new insights into the structure of Bax, a protein responsible for programmed cell death. The team's work, published in Cell Death and Differentiation, sheds light on the dynamics of this protein.
A team of researchers has developed a new mechanism to protect enzymes from oxygen as biocatalysts in fuel cells. The protective mechanism is based on oxygen-consuming enzymes that draw their energy from sugar, allowing for the production of a functional biofuel cell with high efficiency.
Researchers have discovered two brain regions - the prefrontal cortex and hippocampus - whose activity patterns are characteristic of the process of forgetting. Voluntary forgetting enables humans to focus on tasks and is crucial for emotional wellbeing.
Researchers have identified KIN3 as a crucial enzyme connecting cellular signalling pathways involved in fungal developmental processes. The study found that mutants lacking this enzyme were sterile and exhibited developmental disorders.
Researchers developed a modified Nurr1 protein that can enter cells from the outside, showing promise in treating Parkinson's disease. The protein increased tyrosine hydroxylase production, a key enzyme in dopamine synthesis, and protected against neurotoxin-induced cell death.
Researchers at Ruhr-University Bochum gained new insight into the processes involving oxygen-depolarised cathodes, which consume less current than conventional systems. They found that reaction conditions change constantly during chlorine production and are not uniform throughout the electrode surface.
Research found two brain areas associated with action control have varying volumes and connectivity in individuals with high versus low action control. Individuals with poor action control had a larger amygdala, while the dorsal anterior cingulate cortex (dorsal ACC) showed reduced functional connection to the amygdala.
Researchers at Ruhr-University Bochum have developed semi-synthetic enzyme systems using DNA, which can replace protein cofactors. This innovation aims to create more stable biocatalysts that can be used in industry for climate protection and economic gain.
Researchers at Ruhr-University Bochum discovered vulnerabilities in IPsec's IKEv1 protocol, which enable attackers to intercept specific information. The Bleichenbacher attack was successful against four network equipment providers, prompting manufacturers to eliminate security gaps.
Researchers from Ruhr-Universität Bochum used terahertz spectroscopy to gain new insights into the hydration shell of charged particles. They found that hydration shells with a size between two and 21 water molecules were determined for more than 37 salts, depending on the ion's size and valency.
Researchers have found a possible active substance against the hepatitis E virus in naturally occurring silvestrol, which inhibits pathogen replication in cell cultures and mice. Silvestrol is formed by mahogany plants and has been shown to be effective against the virus in both lab tests and animal models.
The ERC grant will help Dr. Saraceno find new highly-efficient sources of light waves in the terahertz range, with potential applications in chemistry, physics and biology. The researchers aim to gain further insights into interactions between water molecules and substances dissolved in it.
Researchers at Ruhr-University Bochum have created a new technique to study the chemical reactions of individual silver nanoparticles in real-time. They found that under certain conditions, these particles transform into poorly soluble silver chloride, which can be toxic for many organisms.
Researchers at Ruhr-Universität Bochum developed a low-cost nickel boride catalyst for plastic production from biorefinery products, offering a sustainable alternative to PET. The catalyst also enables the creation of hydrogen as a potential energy source.
Researchers found that guanylate cyclase enzyme plays a crucial role in the allergic immune response, and its inhibition can lead to reduced symptoms. The study used knock-out mice lacking this enzyme to show that Th1 responses can suppress Th2 responses, resulting in weaker allergy symptoms.
Researchers at Ruhr-University Bochum developed a new infrared sensor method to analyze the structure of proteins affected by active agents. This method provides rapid measurements, allowing for the detection of structural changes within minutes and the identification of binding periods that determine drug efficacy.
Research highlights the physiological and pathophysiological functions of olfactory receptors in human tissues, including their potential applications in cancer diagnosis and therapy. The receptors also regulate skin regeneration, intestinal digestion, and hair growth.
Researchers found two opsin variants in the retina of flashlight fish, activated by low-intensity blue light, which influences behavioral responses. The study suggests that bioluminescence is processed and used to adjust behavior in this species.
Researchers have found that the left hemisphere of the brain processes auditory speech information more rapidly than the right, thanks to a higher number of densely packed neurites in planum temporale. This microstructure is crucial for linguistic superiority.
Researchers from Ruhr-University Bochum have developed new phosphine ligands that enhance gold catalysts' activity and stability. These findings allow for more efficient reactions at lower temperatures with reduced catalyst quantities, promising economic benefits in industries.
Researchers have discovered security weaknesses in the LTE mobile telephony standard, which enables attackers to intercept user data and reroute them to malicious websites. The study highlights that even with HTTPS protocol configuration, some information remains accessible to attackers.
A computational model suggests that older memories are affected in depression, with longer episodes causing more extensive memory deficits. The study's findings imply that major depressive disorder could have far-reaching consequences, including the loss of remote memories that do not recover even after the depression subsides.
Researchers found that TMS facilitates the reorganization of neuronal connections in the visual cortex, which could be beneficial for therapies. A short visual training after TMS treatment can remodel the maps and incorporate biases in information content.
A team of researchers from Ruhr-University Bochum has discovered an olfactory receptor in human bladder tissue that may prove useful for bladder cancer therapy and diagnosis. The receptor, OR10H1, responds to sandalwood scents and inhibits tumour growth when activated.
The study combines STED and SICM microscopy to link protein actin with cell membrane nanostructure, shedding light on the role of the cell membrane in migration processes. This technique offers novel insights into the biochemical organisation of cells and their surrounding membranes.
Researchers at Ruhr-University Bochum found that bioelectrodes containing photosystem I are unstable in the long term due to formation of reactive oxygen species and hydrogen peroxide. This limits their potential for environmentally friendly energy conversion.
Researchers at Ruhr-Universität Bochum have developed a label-free method for rapid cancer diagnosis using infrared imaging, which can perform analysis in just a few minutes. The technique, combined with bioinformatical image analysis, shows promising results with 97% accuracy compared to traditional histopathological analyses.