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Scuola Internazionale Superiore di Studi Avanzati


How our past shapes the present

A study published in Nature Communications demonstrates how the brain constructs the present moment through recent past experiences. The researchers discovered that brief stimuli leave a trace in the brain for almost a minute, accumulating biases in perception that allow subjects to fine-tune their sensory channels over time.

SourceScuola Internazionale Superiore di Studi Avanzati·JournalNature Communications·TypeExperimental study·DateOct 15, 2021

This is how the visual system shows us a more persistent world

A study published in Nature Communications reveals the visual system retains information from moving images, providing a consistent representation of surroundings. The researchers found that neuronal responses in deeper layers of the visual cortex exhibit 'perceptual constancy' and 'intrinsic persistence', ensuring stable encoding and ...

SourceScuola Internazionale Superiore di Studi Avanzati·JournalNature Communications·DateJul 21, 2021

Time perception and sense of touch: a new connection

Researchers at SISSA have discovered a new theory for how we perceive the passage of time in relation to sensory stimuli. The study proposes that the experience of elapsed time is generated when the neuronal representation of a stimulus is collected and summed by an accumulator, explaining why we feel longer vibrations as stronger ones.

SourceScuola Internazionale Superiore di Studi Avanzati·JournalPLOS Computational Biology·DateFeb 10, 2021

Handles and holes in abstract spaces: how a material conducts electricity better

A new theory developed by scientists at SISSA has established a relationship between the presence of 'handles' in the space of atom and molecule arrangements and a material's electrical conductivity. The research found that materials equipped with handles, previously thought to be insulators, can conduct electricity like metals.

In defence mode: this is how Zika virus protects key parts of its genome

Scientists have discovered a simple and ingenious strategy used by the Zika virus to protect important parts of its genome from host cell defence mechanisms. The virus uses an automatic umbrella-like mechanism, where one end of the viral RNA strand is protected while the other is not, allowing it to replicate efficiently.

SourceScuola Internazionale Superiore di Studi Avanzati·JournalNature Communications·DateJul 30, 2020

Spinal injuries: A new technology of electrostimulation for a more effective approach

The study's innovative approach uses a multi-electrode interface to deliver variable targeted stimuli to the spinal cord, increasing the effectiveness of neurorehabilitation and potentially treating a wider range of individuals. The technology has also shown promise in diagnostics, allowing for the assessment of residual activity in th...

In one direction or the other: That is how DNA is unwound

A study published in PNAS reveals that DNA helicases unwind the double strand more easily in one direction than the other, with the speed of unwinding depending on the sequence composition of the bases. This discovery has implications for understanding gene expression and the regulation of cellular activities.

SourceScuola Internazionale Superiore di Studi Avanzati·JournalProceedings of the National Academy of Sciences·DateOct 30, 2019

Dementia and eating disorders: it is a problem of (semantic) memory

A recent study reveals that semantic memory deficits are involved in specific eating disorders in patients with dementia. The research found a correlation between the severity of these eating disorders and reduced performance on semantic memory tests, suggesting that these behaviors depend on the integrity of semantic memory. This brea...

SourceScuola Internazionale Superiore di Studi Avanzati·JournalJournal of Neuropsychology·DateOct 17, 2019

Collecting the right quantity of evidence: How the brain makes a difficult decision

Two studies investigate perceptual decision making in rats and humans, showing that the brain compares incoming sensory evidence to express a decision as soon as it reaches a fixed boundary. The findings support the 'bounded integration' model, which explains how the nervous system accumulates information over time.

The spliceosome: The tailor that coordinates the 'snip and stitch' of genetic information

The study reveals the Spp42 protein plays a crucial role in regulating spliceosome components, essential for transforming genetic information into functional proteins. This understanding may lead to new drugs targeting the spliceosome function to treat diseases such as cancer and leukemia.

SourceScuola Internazionale Superiore di Studi Avanzati·JournalProceedings of the National Academy of Sciences·DateJul 2, 2018