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Tel-Aviv University


CRISPR therapeutics can damage the genome

A new study from Tel Aviv University found that CRISPR therapeutics can lead to a significant loss of genetic material in treated cells, potentially destabilizing the genome and promoting cancer. The researchers detected up to 10% of cells with lost chromosomes, highlighting the need for extra care when using this technology.

SourceTel-Aviv University·JournalNature Biotechnology·DateJul 24, 2022

At least 2,000 species of reptiles are threatened

The first international study of its kind assesses the status of all reptile species, revealing that at least 2,000 species are threatened with extinction. The study found that 50% of turtle and crocodile species face extinction threats, while 30% of forest-dwelling reptiles and 14% of arid area reptiles are in danger.

SourceTel-Aviv University·JournalNature·DateJun 1, 2022

Researchers discovered a mechanism shared by mutations in different genes associated with autism, schizophrenia, and other conditions

A study led by Tel Aviv University researchers reveals a common mechanism underlying genetic mutations associated with autism, schizophrenia, and other neurological disorders. The discovery points to an experimental drug developed by the team as a potential treatment for these conditions.

SourceTel-Aviv University·JournalMolecular Psychology Brain Behavior and Society·DateMay 24, 2022

Discovery: A strain of algae may accelerate the industrial transition from the use of polluting gray hydrogen to environmentally friendly green hydrogen

A new strain of algae has been identified that can produce green hydrogen gas via photosynthesis on an industrial scale. This breakthrough could accelerate the transition to environmentally friendly green hydrogen and reduce pollution. The researchers also plan to develop methods to increase production rates and reduce costs.

SourceTel-Aviv University·JournalCell Reports·DateApr 10, 2022

How do waves form in the sea?

Tel Aviv University researchers develop innovative model that explains wave formation, tested in complex experiments. The model takes into account all unstable harmonics and limitations of previous models, providing high reliability for describing physical situation.

SourceTel-Aviv University·JournalPhysical Review Letters·DateApr 10, 2022

The nanodrug that attacks the cancer twice A single nanoparticle does two jobs: enhancing the effectiveness of chemotherapy and reinvigorating the immune system

Researchers at Tel Aviv University developed a drug delivery system based on lipid nanoparticles that utilize RNA to boost personalized cancer care. The nanodrug enhances chemotherapy effectiveness and reinvigorates the immune system, increasing sensitivity to cancer cells.

SourceTel-Aviv University·JournalScience Advances·DateApr 4, 2022

For the first time: researchers identified brain wounds in IDF veterans with PTSD and relieved their symptoms using hyperbaric oxygen therapy

Researchers from Tel Aviv University found that hyperbaric oxygen therapy (HBOT) relieves PTSD symptoms in treatment-resistant veterans, improving brain function and microstructure. The breakthrough study provides new hope for PTSD sufferers, offering an objective diagnostic tool and potential long-term improvements.

SourceTel-Aviv University·JournalPLOS ONE·DateFeb 23, 2022

Why do locusts form destructive swarms?

Researchers at Tel Aviv University found that a specific type of bacteria, Weissella, becomes dominant in the gut microbiomes of locusts when they form swarms. This change may provide the bacteria with an evolutionary advantage, allowing them to spread and infect more locusts.

SourceTel-Aviv University·JournalEnvironmental Microbiology·DateFeb 9, 2022

In world-first, Tel Aviv University researchers engineer human spinal cord implants for treating paralysis

Researchers from Tel Aviv University have engineered 3D human spinal cord tissues and implanted them in lab models with long-term chronic paralysis, resulting in an 80% success rate in restoring walking abilities. The team aims to conduct clinical trials in human patients within a few years to make the treatment commercially available.

SourceTel-Aviv University·JournalAdvanced Science·DateFeb 7, 2022

Early humans placed the hearth at the optimal location in their cave – for maximum benefit and minimum smoke exposure

Researchers developed a software-based smoke dispersal simulation model to study prehistoric archaeology. They found that early humans placed their hearth at the optimal location in the cave, enabling maximum utilization of fire while minimizing smoke exposure. The study identified a 25sqm area as ideal for locating the hearth.

SourceTel-Aviv University·JournalNature·DateJan 31, 2022

Viruses and game theory

Phages weigh all options and make an informed decision whether to exit the dormant state and attack their bacterial host. The study found that some phage families have developed a complex decision-making strategy, receiving information from neighboring bacteria and controlling communication via arbitrium.

SourceTel-Aviv University·JournalNature Microbiology·DateJan 5, 2022

The link between electrical voltage and brain flexibility a new study by Tel Aviv university found, for the first time; a direct and significant link between changes in G-protein-coupled receptors and the brain’s ability to adapt to external changes

A Tel Aviv University study found a significant link between changes in G-protein-coupled receptors and brain adaptability. Disabling the voltage sensor of these proteins caused uncontrolled brain flexibility, leading to excessive habituation to odors.

SourceTel-Aviv University·JournalNature Communications·DateJan 4, 2022

Medicinal cannabis oil found effective for treating autism

Researchers at Tel Aviv University successfully treated autism in animal models with medical cannabis oil, improving behavioral and biochemical parameters. The treatment showed significant improvement in compulsive and anxious behaviors, and a decrease in the concentration of the arousing neurotransmitter glutamate.

SourceTel-Aviv University·JournalTranslational Psychiatry·DateDec 19, 2021

Extensive use of smartphones by parents might damage toddler’s development and have far-reaching consequences

A recent study from Tel Aviv University found that mothers' smartphone use reduces toddler interaction by a factor of four. Reduced interaction can have far-reaching consequences on child development, including language and social skills. The study also found no significant difference between browsing smartphones and reading magazines.

SourceTel-Aviv University·JournalChild Development·DateDec 15, 2021

Researchers from Tel Aviv University identified the biological mechanism causing nerve destruction in the Motor Neuron disease ALS

Researchers from Tel Aviv University have identified the biological mechanism causing nerve destruction in ALS, a fatal neurodegenerative disease. They found that TDP-43 protein accumulation in neuromuscular junctions inhibits local protein synthesis and mitochondrial activity, leading to degeneration and death of motor neurons.

SourceTel-Aviv University·JournalNature·DateDec 14, 2021

Experimental compound, which has received orphan drug and pediatric rare disease designations from the FDA, displays effectiveness in treating symptoms of Autism and Alzheimer’s disease

An experimental drug called NAP has been found effective in treating a broad spectrum of symptoms related to autism, intellectual disability, and Alzheimer's disease. Researchers discovered that NAP normalizes brain function in mice modeling ADNP syndrome, a rare disorder linked to these conditions.

SourceTel-Aviv University·JournalBiological Psychiatry·DateDec 8, 2021