A team from UNIGE and HUG used information theory to study the molecular regulations behind cancer cell adaptation to targeted therapies. They found that a large reversible component of resistance exists, which can be modulated by therapeutic combinations.
Researchers found that emotion knowledge, cooperative social behavior, and locomotor activity are interrelated and associated with numerical skills in preschool children. These fundamental skills can promote numerical learning and suggest that locomotor activity should be added to early education.
Researchers used AI to analyze brain activity during deep sleep, finding that the brain relives memories of rewarding experiences and consolidates them through an internal dialogue. This process enhances memory performance, particularly for emotionally charged events.
The Swiss team proposes a three-pillar strategy for semantic framework development, compositional language creation, and adaptation to specific data models. This approach aims to unify vocabularies and facilitate cross-referencing of mutually intelligible data from different sources.
An international team has developed a method to analyze ancient DNA in museum specimens, allowing for their placement on the evolutionary timeline. The technique enabled researchers to trace the evolutionary history of several species over tens of millions of years.
Researchers at UNIGE found that chromosomal site location is transmitted through an epigenetic process, allowing offspring to inherit correct positions even without gene information. This epigenetic memory only lasts for one generation and affects the survival of mutant worms.
Researchers from UNIGE and Harvard Medical School have discovered the difference between desired immune responses targeting cancer cells and unwanted responses affecting healthy tissue. By understanding these differences, they aim to develop new therapeutic approaches that minimize toxic side effects and maximize treatment efficacy.
A new study found that a special type of brain training based on neurofeedback enables people with attention deficit disorder to improve their ability to concentrate. The training is linked to an enhanced response from the brain's P3 wave, which reflects integration of information in the brain.
Researchers have identified the structure and functions of RON13, a kinase essential for the invasive mechanism of Toxoplasma gondii in humans. The parasite's ability to infect cells is hindered without RON13, providing a potential target for new therapies.
A team of geologists reviewed the literature on volcanic eruptions, determining that most magma rising from depth doesn't cause an eruption. Older volcanoes produce less frequent but larger eruptions. The analysis helps refine models to reduce the impact of volcanic eruptions on nearby populations.
A UNIGE team has identified an RNA helicase regulator in Pseudomonas aeruginosa that significantly reduces its infectious power and virulence. The absence of this protein makes the bacteria almost harmless while remaining alive.
A single gene mutation can slow down cell division, preventing proper brain development and leading to microcephaly. This process involves the dysregulation of microtubules, which are essential for distributing genetic material between new cells.
Researchers at Université de Genève and University of Basel study the structure of cellular receptors and molecules that activate immune cells. They discovered a 'lock and key' mechanism involving specific amino acids in chemokine structures, allowing for fine-tuning of immune system activation.
Researchers at UNIGE found that digital initiatives within country offices have the strongest impact on changing ways of working, embedding new skills, and restructuring teams across the UN. The study highlights the power of bottom-up innovation, where ideas can spread from country to country, achieving scale and changing the organizat...
Autistic children who are bilingual show improved theory of mind and executive function skills compared to monolingual peers. Bilingualism enables children to partially compensate for deficits in these areas, allowing them to focus on one language while inhibiting another.
Researchers at UNIGE create 3D spheroidal tumor models incorporating tumor cells and patient-specific immune cells to test treatment efficacy. This innovative approach enables personalized treatment options, potentially reducing reliance on animal experiments.
Researchers found that selective serotonin reuptake inhibitors can reduce deterioration of intellectual abilities in individuals with a microdeletion of chromosome 22. The study suggests a potential neuroprotective effect and opens up new research possibilities.
The study reveals that glacial lake outburst floods in the Himalayan region and Tibetan plateau could triple in the coming decades, posing a significant threat to communities and infrastructure. The risk of transboundary disasters will also increase, with new hotspots emerging in regions like the Western Himalaya and Pamir.
Scientists from UNIGE and UZH used a statistical physics approach to study wound healing, identifying the scales of dominant cell interactions that govern tissue growth. The results allow for better analysis of cell front behavior in both healthy tissue and tumour development.
Researchers at UNIGE discovered a new mechanism for regulating RNA maturation dependent on diet, finding that methylation of specific mRNA sequences leads to its degradation. This control mechanism ensures a fair balance of methylations and prevents aberrant reactions, which can cause diseases.
Researchers from UNIGE used mice to study the complex processing of light by the retina, revealing that both light intensity and its temporal shape influence the signal sent to the brain. The findings, published in Science Advances, may lead to new diagnostic and therapeutic possibilities for eye weaknesses.
Researchers found that eye contact causes a distortion in temporal perception, making time seem shorter than it really is. In contrast, deviated gazes do not impact time perception.
A team of scientists from UNIGE has identified a crucial role for a micro-peptide in determining the sperm that will fertilize an egg in Drosophila females. The peptide plays a key part in the competition between spermatozoa from different males, and its absence leads to reduced fertility in subsequent matings.
Researchers found an indirect link between cardiorespiratory fitness and higher marks in mathematics and French 2. Better executive functions, specifically cognitive flexibility, were also associated with improved academic performance. The study emphasizes the importance of physical education classes in schools.
Scientists from UNIGE discovered that paxillin helps cells perceive their environment and dock at the right place using cellular crampons. Without functional paxillin, cells can't attach properly and slip continuously.
Fish can have scaled, armoured or naked skin; researchers found that only naked fish can develop a bony armour. The protective state of their skin influenced their choice of open water or sea floor habitats.
Researchers found that men exposed to endocrine disruptors in utero are twice as likely to have low semen volume and sperm count. Exposure to pesticides, phthalates, and heavy metals is associated with poorer sperm quality.
Researchers at UNIGE have discovered a vestigial form of conoid organelle in the malaria parasite, which could play a role in host invasion. The study uses expansion microscopy to view the parasite's cytoskeleton at an unprecedented scale, shedding new light on its life cycle.
Scientists at UNIGE have developed a fluorescent dye to track the movement of kinesin proteins within cells, revealing their path and direction. This breakthrough enables researchers to study the fundamental question of protein transport and cargo distribution in cells.
Researchers studied ash from volcanic eruptions, discovering premature sedimentation and the rafting effect. These findings will refine forecasting models used by VAACs to predict volcanic ash clouds' impact on aircraft routes.
A recent study analyzing over 20,000 genomes found similarities and differences in genetic patterns among anorexia nervosa, bulimia nervosa, and binge-eating disorder. The research team discovered that while these eating disorders share genetic risk with psychiatric disorders, they differ in their association with body weight regulation.
Researchers at SCCL have found that CD4 T lymphocytes, which typically support immune responses, can also kill cancer cells directly. Up to a third of these cells were able to destroy tumor cells within five hours.
Researchers discovered that cells within a single organ can synchronize their circadian rhythms without receiving timing cues from the brain or other external signals. This finding suggests a novel mechanism of coordination, where cells exchange molecules to stay in phase.
A study by MSF and UNIGE found that insulin can be stored at temperatures ranging from 25°C to 37°C for four weeks without losing its potency or efficacy. This breakthrough allows people with diabetes to manage their condition independently, reducing the need for daily hospital visits.
Researchers have developed tactile books with 3D mini-scenarios that allow blind children to explore and identify objects using gestures and body simulations. This innovative approach has been shown to narrow the perception gap between blind and sighted children, enabling them to recognize objects more easily.
Researchers analyzed human, animal skeletons and plant remains to study the evolution of the Swiss diet during the Bronze Age. They found no differences in diet between men, women, or children, but a shift towards more intense agriculture and the introduction of new cereals like millet.
A study by Université de Genève found that online courses deepen inequalities between high-potential and struggling students by 5%. The research suggests that different behaviour patterns, such as preferring face-to-face classes or streaming, contribute to these disparities.
A UNIGE study found that people who met their partners on dating applications have stronger cohabitation intentions and desires to have children. The results also show that couples formed through apps have diverse socio-educational profiles, leading to increased long-distance relationships.
Researchers at Université de Genève have developed a technique that can predict epileptic seizure periods between one and several days in advance. By recording neuronal activity over six months, they can detect individual cycles of epileptic activity and provide information about the probability of a future seizure.
A study by Université de Genève found that pretend play-based curriculum improved children's ability to recognize emotions and regulate their behavior. The program, introduced in classes aged five and six, enhances emotional vocabulary and promotes prosocial behavior.
Physicians from the University of Geneva followed nearly 700 people with SARS-CoV2, finding that 33% still reported symptoms like fatigue, loss of smell or taste, and shortness of breath six weeks after diagnosis. A specific consultation for long COVID patients has been set up to improve care.
Scientists have discovered 17 genetic abnormalities that cause brain aneurysms, providing a new understanding of the disease and potential markers for instability. The study also highlights the importance of genetic predisposition to high blood pressure and smoking in developing intracranial aneurysms.
A team from UNIGE used a specially developed video game to investigate the emergence of emotions, confirming that brain components respond in parallel distributed throughout the brain. The results show transient synchronisation generating an emotional state, involving areas like the somatosensory and motor pathways.
A study found that visual processing units are identical in size across primate species, from the world's smallest mouse lemur to humans. This preservation suggests an early evolution of primate vision and highlights the importance of conservation efforts for endangered species.
Researchers from Université de Genève analyzed 16 glass beads found in Mali and Senegal, discovering they were made of Egyptian, Levantine coast, and Middle Eastern glass. The study sheds light on sub-Saharan Africa's extensive trade networks with Europe and Asia during the region's early development.
Research finds that nanosilver disturbs the metabolism of algae, making their membranes more permeable and reducing photosynthesis. This can have significant impacts on the aquatic food chain and oxygen production. The study uses metabolomics to detect early changes induced by nanoparticles.
Researchers found that high concentrations of fine particles less than 2.5 micrometers in size can modulate the waves of SARS-CoV-2 contamination and explain the profile of the COVID-19 pandemic. Acute exposure to these particles aggravates respiratory, pulmonary, and cardiovascular issues, promoting severe disease progression.
Researchers at UNIGE have identified sulfur molecules that can effectively block the uptake of SARS-CoV-2 viruses by cells. The team found inhibitors up to 5,000 times more effective than existing treatments, providing a promising lead for developing new antivirals.
A study published in Nature Communications reveals that species diversity is optimal for equatorial and tropical rainforests, while abundance of trees is key to carbon storage in colder regions. The findings have substantial practical relevance for climate change mitigation strategies.
Scientists from UNIGE and HUG identified the essential role of circadian clocks in beta cell regeneration. The study found that regeneration is significantly greater at night, when mice are active, and that the BMAL1 gene plays a crucial role in this process.