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Menopause hormone therapy does not appear to impact dementia risk

A comprehensive review of prior research found no evidence that menopause hormone therapy increases or decreases dementia risk in post-menopausal women. The study included data from over 1 million participants and analyzed the impact on mild cognitive impairment and Alzheimer's disease, with no significant association found.

SourceUniversity College London·JournalThe Lancet Healthy Longevity·TypeSystematic review·DateDec 22, 2025

Tech savvy users have most digital concerns

A new study found that highly educated, Western European millennials have the most digital concerns, with individuals having higher levels of digital literacy being the most affected. The research also found that people's perceptions of digital harm are heightened by their level of digital exposure and knowledge.

SourceUniversity College London·JournalInformation Communication & Society·TypeData/statistical analysis·DateDec 14, 2025

Air pollution may reduce health benefits of exercise

A new study found that long-term exposure to toxic air can weaken the health benefits of regular exercise. The study analyzed data from over 1.5 million adults and found that people living in high pollution areas had a reduced risk of dying, but not eliminated, despite exercising regularly. Clean air can still enhance health gains, wit...

SourceUniversity College London·JournalBMC Medicine·DateNov 27, 2025

Unearthing the City of Seven Ravines

Archaeologists uncover vast planned settlement Semiyarka, dating back to 1600 BC, which challenges current understanding of steppe societies and reveals complex bronze production systems. The site provides insight into a period of history when nomadic communities transitioned into permanent settlements.

Ageing stars may be destroying their closest planets

Astronomers at UCL and the University of Warwick discovered that aging stars are destroying giant planets orbiting closest to them. The researchers analyzed nearly half a million stars and found that planets were less likely to occur around stars that had expanded and cooled enough to be classed as red giants.

SourceUniversity College London·JournalMonthly Notices of the Royal Astronomical Society·DateNov 5, 2025

Antidepressants improve core depressive symptoms early on

A new analysis of the PANDA trial found that sertraline contributes to improvements in low mood and suicidal thinking within two weeks of taking the drug. The study also revealed an improvement in emotional symptoms of depression within two weeks, with continued benefits from six weeks to 12 weeks.

SourceUniversity College London·JournalNature Mental Health·TypeRandomized controlled/clinical trial·DateOct 30, 2025

Humans evolved fastest amongst the apes

Researchers analyzed ape skulls to find that humans evolved the largest brain size and flattest face among closely related species. This rapid evolution suggests a strong link between cranial structure and cognitive abilities, but social factors may also play a role in human skull development.

SourceUniversity College London·JournalProceedings of the Royal Society of London B Biological Sciences·TypeComputational simulation/modeling·DateOct 21, 2025

Landmark gene therapy study shows safety for children

A landmark study published in the New England Journal of Medicine reports the long-term safety and efficacy of gene therapy for children with ADA-SCID, a rare immune disorder. The treatment resulted in a 100% survival rate and over 95% cure rate, with patients able to respond to routine childhood vaccinations.

SourceUniversity College London·JournalNew England Journal of Medicine·TypeObservational study·DateOct 15, 2025

New drug combination offers hope for men with advanced prostate cancer

A new drug combination has shown promising results in delaying the progression of advanced prostate cancer in patients with specific genetic mutations. The trial, led by UCL researchers, found that combining niraparib with standard treatment delayed disease recurrence and improved survival rates for eligible patients.

SourceUniversity College London·JournalNature Medicine·TypeRandomized controlled/clinical trial·DateOct 7, 2025

Racial discrimination may increase psychosis risk

A major review of international evidence found that racial discrimination contributes to the development of psychosis, with people experiencing discrimination being 77% more likely to develop psychotic symptoms. The study highlights the need for public health action to tackle systemic racism and its impact on mental health disparities.

SourceUniversity College London·JournalPLOS Mental Health·TypeSystematic review·DateSep 24, 2025

New ultrasound helmet enables deep brain stimulation in people without surgery

A new ultrasound device has been developed to precisely stimulate areas deep in the brain without surgery, offering new possibilities for neurological research and treatment. The technology features a special helmet with 256 elements that target specific parts of the brain, and includes a soft plastic face mask to keep the head still.

SourceUniversity College London·JournalNature Communications·TypeExperimental study·DateSep 5, 2025

Promising new drug for people with stubborn high blood pressure

A Phase III clinical trial has shown that baxdrostat significantly lowers blood pressure in people whose levels remain dangerously high despite taking multiple existing medicines. The study found that nearly 4 in 10 patients achieved healthy blood pressure levels, compared to fewer than 2 in 10 on placebo.

SourceUniversity College London·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateAug 30, 2025

Molecular test personalizes prostate cancer treatment

A new study found that a gene expression test can help guide therapy choices for prostate cancer patients with metastatic disease. The Decipher Prostate Genomic Classifier test identified groups of patients who are more likely to benefit from docetaxel chemotherapy, reducing the risk of death by 36%.

SourceUniversity College London·JournalCell·TypeRandomized controlled/clinical trial·DateAug 28, 2025

Surgery to treat chronic sinus disease more effective than antibiotics

A major clinical trial led by University College London has found that surgery is more effective than long-term use of antibiotics in treating chronic rhinosinusitis. The study, which involved over 500 patients, showed that sinus surgery significantly improved symptoms and quality of life for those who underwent the procedure.

SourceUniversity College London·JournalThe Lancet·TypeRandomized controlled/clinical trial·DateAug 28, 2025

US oil and gas air pollution causes unequal health impacts

A major new study quantifies the health impacts of outdoor air pollution from US oil and gas activities, revealing widespread disparities in exposure and health burden across racial and ethnic groups. The research estimates 91,000 premature deaths annually, with Black, Asian, Native American, and Hispanic populations most affected.

SourceUniversity College London·JournalScience Advances·TypeComputational simulation/modeling·DateAug 22, 2025

Boys can help break taboo around periods

A new study by University College London researchers suggests that lessons on periods in British schools should be more comprehensive, covering the impact on well-being and academic performance. The study also recommends involving boys in menstruation education to promote better understanding and support for friends and future partners.

SourceUniversity College London·JournalWomen s Health·TypeSurvey·DateAug 19, 2025