A new study found a correlation between colder temperatures and northern regions in the US and an increased risk of diabetes diagnoses in dogs. Diabetes diagnoses were more common in winter and in the North compared to other seasons and regions.
A team of researchers, including atmospheric chemists from the University of Pennsylvania, identified a novel pathway for sulfur particle formation in Venus' atmosphere. This new understanding sheds light on the source of ultraviolet-absorbing emissions and offers cautionary notes for geoengineering efforts.
Researchers from the University of Pennsylvania establish a relationship between topology and entanglement, tying two major principles in physics together. The connection reveals that the genus of the Fermi surface is closely related to a measure of quantum entanglement called mutual information.
Researchers at Penn Dental Medicine have developed a microrobotics system to access the root canal with controlled precision, treating and disrupting biofilms. The technology enables diagnostic and therapeutic applications, allowing for personalized treatment plans.
A study analyzed 10 years of cable TV news and found that networks like Fox and MSNBC have shifted further to the right and left, respectively. The ideological gap between channels became extreme after the 2016 Presidential election, particularly in primetime programming.
A new study successfully introduces healthy photoreceptor cells derived from stem cells into the retinas of dogs, marking significant progress toward a cell-based therapy for blindness. The treatment enables cells to survive and form connections with existing retinal cells, paving the way for a regenerative medicine approach.
Researchers have identified a new protein called IFT80 that regulates osteoclasts, the cells responsible for breaking down bone. The study found that mice lacking IFT80 developed severe osteopenia, highlighting its potential as a therapeutic target for treating bone loss diseases.
Researchers developed artificial microtubules to transport microscopic cargo along magnetic stepping stones, overcoming fluid flow obstacles. The technology could facilitate targeted drug delivery and treat blocked vessels or cancerous tumors.
Research by Jeremy Wang at the University of Pennsylvania has discovered that DOT1L, a stem cell self-renewal factor, is essential for mice to produce sperm throughout their adult lives. The team found that mice lacking DOT1L fail to maintain spermatogonial stem cells and lose the ability to continuously produce sperm.
Aerosols generated by musicians dissipate within 6 feet, settling into the background air draft. Flute-generated aerosols traveled farther due to airflow over the instrument.
Researchers from the University of Pennsylvania have developed a hands-free system that uses shapeshifting microrobots to brush, floss and treat teeth. The microrobots use magnetic fields to conform to different shapes and release antimicrobials to kill oral bacteria.
A study by Diane Spatz of the University of Pennsylvania School of Nursing found that donating milk served as an important part of the grieving process for some parents who had lost a baby before or at birth. This practice helped them form a connection with their child, reduce grief, and create a positive outcome for another family.
Researchers found that personal narratives increase empathy and encourage prosocial behaviors, particularly towards higher-risk groups like the incarcerated or healthcare workers. The study suggests using storytelling can shift an individual's perspective and promote behavioral changes in public health interventions.
Bacteria's CRISPR system uses spacers to store viral information, but must balance risk of autoimmunity with immune memory. Longer spacers reduce autoimmune response risk, allowing more spacers to be stored without triggering an immune reaction.
Biologists at the University of Pennsylvania have discovered a two-sided genomic arms race between satellite DNA and its binding proteins in fruit flies. The study reveals that when these elements interact, significant costs to fitness can occur, including impacts on fertility and cancer development.
A new study from the University of Pennsylvania suggests that negative partisanship - the perception that Democrats or Republicans are driven by hatred for their opponents - is exaggerated. In fact, research found that people's primary motivations for choosing a party are more strongly tied to love for their own party.
A new study analyzed genomic data from global populations to identify genetic variants linked to COVID-19 severity. The investigation found dozens of genomic variations in critical genes, suggesting these may have evolved to protect against viruses similar to SARS-CoV-2.
A new study found that genetics and environmental influences both contribute to socioeconomic status's impact on the brain, with different effects on various brain regions. The research used the UK Biobank dataset to analyze nearly 24,000 individuals and identified specific brain regions related to socioeconomic status.
A study published in Cell reveals that individuals with gum disease are more susceptible to developing arthritis due to alterations in immune cell precursors in the bone marrow. The researchers also found that this association may prompt a reconsideration of how bone marrow donors are selected.
Researchers discovered that checkpoint inhibitors can activate regulatory T cells, which can counteract the immune response. Blocking PD-L1 enhanced effector Treg activity, reducing ability to control parasite infections. This finding highlights complexity of immune system's balance between controlling pathogens and protecting healthy ...
Scientists tracked Cryptosporidium in real-time, revealing a simplified lifecycle that completes in three days with only three stages: asexual cells, male cells, and female cells. This understanding paves the way for potential vaccines or therapies to combat the disease.
Researchers found that rhesus macaques with more grooming partners had larger brain areas for social decision-making and empathy, specifically the mid–superior temporal sulcus (STS) and ventral-dysgranular insula. The study suggests that social connections influence brain structure in nonhuman primates, with possible implications for h...
Researchers at the University of Pennsylvania found a correlation between household income, building age, and proximity to former lead smelters with elevated blood-lead levels in children. The study highlights environmental justice issues that disproportionately affect low-income and minority populations in Philadelphia.
A collaborative study from the University of Pennsylvania demonstrates topological control capabilities in an acoustic system at technologically relevant frequencies. The researchers have successfully shown that topological phenomena occur at higher frequency ranges, enabling unique signal propagation properties.
Researchers from the University of Pennsylvania discovered that disordered materials can retain a memory of external forces, allowing them to predict when and how they will flow. By analyzing individual particle distributions, scientists can determine a material's stability and response to stressors.
Researchers have developed a gene therapy that restores night vision in dogs with congenital stationary night blindness (CSNB), a condition affecting the ON bipolar cells. The treatment enables dogs to navigate mazes in dim light and has a lasting therapeutic effect, paving the way for potential human treatments.
Researchers found that fruit flies underwent widespread physical and genomic adaptation within weeks, with changes documented in 60% of their genome. The study's findings suggest a new paradigm for understanding the timescale of evolution, highlighting rapid and dynamic adaptation to environmental conditions.
A newly described softshell turtle, Hutchemys walkerorum, lived in North Dakota 66.5 million years ago, surviving the end-Cretaceous mass extinction alongside Tyrannosaurus rex and Triceratops. The find sheds light on the evolution of softshell turtles during this period.
A new study using a dataset of over 36,000 adults found that light-to-moderate alcohol consumption was associated with reductions in overall brain volume. The association grew stronger with increasing levels of alcohol consumption, comparable to aging two and three years, respectively.
A new study from the University of Pennsylvania found that increased awareness of discrimination against Black Americans during the BLM protests led to a significant shift in voter preferences towards Democrat Joe Biden. However, concerns about COVID-19 had little effect on vote choice.
A study by researchers at the University of Pennsylvania found that a domestic cat was infected with the SARS-CoV-2 delta variant, but without significant genetic changes. This discovery highlights the virus's ability to infect a wide range of hosts and raises questions about its evolution in different species.
The study reveals that asbestos minerals undergo changes that resemble self-defense when internalized by human lung cells. These changes include the formation of an iron-rich layer on the minerals, which may be a mechanism to protect the cell from toxicity.
Ta2NiSe5 exhibits broken symmetry, which has significant implications for its use in future devices. The researchers developed a novel technique to probe subtle symmetry breaking in crystalline materials, providing a platform for finding similar properties in other types of materials.
To survive relativistic speeds, the new sail needs to billow like a parachute, with a curved structure that can withstand hyper-acceleration. The design also incorporates nanoscale patterning to dissipate heat generated by powerful lasers, enabling faster travel times.
Researchers from the University of Pennsylvania and Oak Ridge National Laboratory have identified a cascade of inflammatory signaling that precedes skin ulcers in atopic dermatitis. A mouse model lacking an activator of NF-kB signaling led to the development of skin lesions, shedding light on the early stages of the condition.
Researchers at the University of Pennsylvania found that changing social strategies between settings can lead to more cooperative behavior in a society. In a model with spillover between domains, cooperation is favored when actors can observe and imitate each other's behaviors in different contexts.
A new study published in PNAS reveals that border walls damage a country's international image, with real implications for soft power. The study found that participants had negative perceptions of countries with border walls, regardless of their political views or distance from the border.
A new chewing gum infused with plant-grown ACE2 protein can neutralize the SARS-CoV-2 virus in saliva, potentially reducing transmission risk. The gum, developed by researchers at the University of Pennsylvania, was tested on saliva samples from COVID-19 patients and found to significantly reduce viral load.
Researchers at the University of Pennsylvania have discovered a new approach to triggering differentiation in AML cells, potentially treating a wider range of patients. By inhibiting an enzyme that blocks cellular differentiation, AML cells can lose aggressive growth traits and mature into new cell types.
A new study reveals a shared molecular pathway governing sperm motility among corals, sea urchins, and humans. Researchers found that corals have a pH-sensing enzyme similar to one in human sperm, which signals when to swim.
A team of University of Pennsylvania biologists used citizen science data to create a comprehensive abundance map of the black-legged tick, responsible for transmitting Lyme disease. By correcting biases in the data, they were able to increase its value and provide insights into tick distribution across the Northeast US.
A new study suggests that atmospheric conditions in the stratosphere pose a challenge to generating sulfuric acid, a crucial component of a proposed geoengineering strategy to mitigate climate change. Researchers found that solar radiation causes HOSO2 to quickly photolyse, breaking it down into harmful sulfur dioxide, which may reduce...
A research team has identified a subset of cerebellar neurons that signal satiation after eating, leading to reduced food intake in mice. The findings suggest a novel target for therapies that could curb overeating and obesity.
A University of Pennsylvania study found that clinician peer networks significantly reduce health care inequities and disparities. The study led by Professor Damon Centola showed that clinicians who initially exhibited significant bias could change their clinical recommendations to exhibit no bias.
Researchers at Penn discovered a new suite of antimicrobial peptides, hidden within the human genome, which showed promising natural antibiotic potential. The peptides displayed antimicrobial activity against various pathogens, including E. coli and staph infection-causing bacteria.
A study by the University of Pennsylvania and Indiana University found that a nanozyme therapy, combining ferumoxytol and hydrogen peroxide, significantly reduced the buildup of harmful dental plaque and targeted bacteria responsible for tooth decay. The treatment effectively killed Streptococcus mutans bacteria while leaving other ora...
Research from University of Pennsylvania team shows that vaccine mandates have positive effects on vaccination intentions, particularly for those who oppose forced behavior. Mandates strengthen vaccination intentions, regardless of racial or ethnic group, and for individuals with a disposition towards psychological reactance.
A new study by University of Pennsylvania researchers uses human gingiva-derived mesenchymal stem cells to guide nerve growth and regeneration, achieving similar results as traditional autograft procedures. The approach has potential for treating larger nerve gaps, including those resulting from oral cancer surgery.
Researchers identified six major themes associated with smoking risk and protective factors among TGE adults, including experience of stress, gender affirmation, and environmental cues. The study aims to design culturally sensitive messaging for smoking cessation through social media and inform further community-engaged research.
A team of researchers developed an algorithm that infers the communicative needs of different linguistic communities regarding colors. The study found that warm hues like reds and yellows have a higher demand for language, while less prominent colors are underrepresented.