Researchers have identified three new subgroups of neuroblastoma based on genetic traits, expected outcomes, and distinguishing features. These subgroups offer clues as to which treatments may be most effective, potentially improving prognosis and quality of life for children with cancer.
A new study by the University of Southampton found that a commonly used questionnaire for monitoring depression treatment in primary care does not provide immediate benefits. However, patients who tracked their scores reported improved overall wellbeing and quality of life after six months.
Scientists have discovered six proteins that can accurately diagnose tuberculosis (TB). The breakthrough study paves the way for a simple blood test to detect the bacteria, which could prevent millions of cases annually. TB is the world's deadliest infectious disease, killing over one million people each year.
Researchers at the University of Southampton have developed a method for fast mixing using droplet microfluidics, allowing for the creation of 'movies' of proteins in action. This enables scientists to observe proteins in motion and gain insights into their function.
Researchers monitored astronauts' muscle health using a handheld device, revealing crucial lower leg muscles are at risk of weakening. The technology could also help monitor muscle health in neuro-musculoskeletal conditions like Parkinson's Disease.
Research has identified common issues homeless women face when experiencing periods, including practical challenges and feelings of embarrassment. The study highlights the need to address menstrual health resource provision as a basic human right.
A study by the University of Southampton found a strong connection between daily suicides, people's expectations formed by professional economic forecasts, and subsequent economic performance. Negative economic shocks can lead to feelings of lack of identity and purpose among vulnerable populations, increasing the risk of suicide.
Physicists at the University of Southampton successfully detect weak gravitational pull on microscopic particles using a new technique. The experiment, published in Science Advances, could pave the way to finding the elusive quantum gravity theory.
A new review of research evidence suggests that having fewer nurses on shift in emergency departments is associated with longer waits, patients leaving without being seen, and a higher number of cardiac arrests. This is linked to increased pressure on the healthcare system due to increasing demand and complex health problems.
Scientists discovered that bacteria form partnerships between different defence systems to create a formidable force against phage viruses. This discovery could lead to new strategies for combating antimicrobial resistance and developing phage therapy as an alternative to antibiotics.
Recent research suggests that problems with sleep and internal body clock can trigger or worsen psychiatric disorders. The study highlights the importance of understanding the relationship between sleep, circadian rhythms, and mental health, which could lead to new preventative measures and therapies.
The study found that nurses prefer consistent and predictable shift patterns to help them balance work with personal commitments. Many expressed concerns over caring for family members, while others valued the flexibility of longer shifts with more overtime opportunities.
The UK Generations and Gender Survey found a rise in young adults intending not to have children, with environmental concerns less prevalent among Gen Z. High childcare costs also differ greatly by household income, restricting access to affordable services for low-income families.
Researchers found that human migration to the South Pacific Islands led to a reduction in the uniqueness of plant species, with homogenization occurring over approximately the last 3,000 years. This process coincides with human occupation and modification of flora through introduced non-native plants and activities.
Researchers have found that ultraviolet laser light can degrade coronavirus particles by damaging their genetic material and protein spikes. The study reveals the effectiveness of UVC laser radiation in inactivating SARS-CoV-2, with applications for public disinfection and decontamination.
Researchers have successfully engineered the plant microbiome to boost beneficial bacteria that protect plants from disease. This breakthrough could substantially reduce pesticide use and unlock opportunities to improve plant health.
A new study has found that the QbTest, a widely used computerized test for Attention-deficit/hyperactivity disorder (ADHD), is not accurate enough to be used as a standalone diagnostic tool. The researchers emphasize that the QbTest should be used in conjunction with clinical assessment and judgment to arrive at a diagnosis.
A study published in PLOS Medicine found that 90% of pregnant women in high-income countries lack key vitamins necessary for healthy pregnancies and fetal development. The situation is expected to worsen as more people adopt plant-based diets, leading to increased risk of nutrient deficiencies.
Research suggests that big data and artificial intelligence can aid in developing bespoke therapies for psychosis. The study proposes refining existing therapies and exploring alternative approaches to improve outcomes for patients.
Rising sea temperatures in the Mediterranean may drive juvenile bluefin tuna out of their nurseries, where they'll be caught in existing fisheries, requiring adaptions to fishery methods. The research found that waters above 28 degrees Celsius will adversely impact bluefin growth.
Research shows some barnacles morphing to protect themselves from predators, while others remain unchanged in cooler regions. The study found bent morphs prevalent in warmer waters, but absent in colder areas.
Researchers found that a small fraction of eligible patients are being approached to consider eye donation, despite both healthcare professionals and patients having favorable views towards it. The study highlights the need for practice change to offer patients who wish to donate as part of routine end-of-life care.
Researchers compared sea stars to other deuterostomes to learn about their unique body plan, finding that genes controlling development of the ectoderm were correlated with arm patterning in echinoderms. This suggests echinoderms may have evolved by losing trunk region of bilateral ancestors.
Children diagnosed with ADHD at a young age are just as likely to retain the diagnosis in adulthood as their older peers, according to a new study. The research, which examined data from over 6,500 patients globally, suggests that the youngest children in class are not more likely to lose the diagnosis over time.
Researchers identify immune cells responsible for some hard-to-treat asthma cases, particularly in men who develop asthma later in life. These cells can cause severe inflammatory responses and do not respond to treatment.
Researchers propose that black holes can exist in equilibrium as 'perfect pairs' within an ever-expanding Universe. This concept challenges traditional understanding of black hole behavior and interactions.
Researchers found a 'well-watered corridor' in the Levant that funnelled hunter-gatherers towards western Asia and northern Arabia via Jordan. This route, favoured by travelling Homo sapiens heading north, was used to populate Asia and then Europe over tens of thousands of years.
Research at the University of Southampton found that 12-hour plus shifts increase incidents of self-harm, threatening behavior, and violence. The study suggests that nurse managers should avoid implementing long shifts as a blanket solution.
A study found that anti-immigrant prejudices, particularly towards Muslims, contribute to increased tolerance of LGBT+ individuals in Western democracies. The researchers discovered that shifts in tolerance are heavily conditioned by who the opponents of LGBT+ rights are.
Researchers have uncovered a major Palaeolithic cave art site in 'Cova Dones', Spain, with over 100 ancient motifs dating back at least 24,000 years. The site features a wide range of techniques and animal representations, including clay-based paintings.
A new study reveals that boys who smoke in their early teens may damage the genes of their future children, leading to increased risks of developing asthma, obesity, and low lung function. Researchers investigated epigenetic profiles of 875 people aged 7-50 and found changes associated with fathers' teenage smoking.
Scientists have discovered that corals digest their symbiont algae to access essential nutrients, allowing them to grow rapidly even in nutrient-poor waters. This breakthrough resolves the long-standing mystery of coral reef formation and sheds light on the critical role of symbiotic relationships in coral survival.
A new study found that around one in five people with compromised immune systems have no COVID-19 antibodies after three or more vaccinations. The MELODY study identified specific groups at higher risk of not producing antibodies, highlighting the need for targeted interventions and booster vaccines.
Researchers discovered that tectonic plate breakup is the main driving force behind diamond-rich magmas and eruptions from deep inside the Earth. The team's findings could shape the future of diamond exploration, informing where diamonds are most likely to be found.
A new study finds public backing for biofuel and hydrogen as alternative fuels to reduce greenhouse gas emissions in the global shipping industry. The research suggests that nuclear power is also a viable option, while ammonia has the least public support due to its perceived risks.
Research by the University of Southampton found that repeated COVID-19 vaccine doses increase immune response in blood cancer patients, generating higher-quality antibodies. Booster vaccinations are essential for maintaining protection against COVID-19 in immunocompromised individuals.
A new study analyzed coverage of BECCS in 166 newspaper articles to understand public opinion on the energy technology. The research identified eight key storylines, including Pro-BECCS narratives that emphasized its necessity and Revolutionary technology, alongside Anti-BECCS lines that highlighted environmental concerns.
Researchers at the University of Southampton discovered a British dinosaur tooth that doesn't match any known spinosaur species, revealing hidden diversity in the region's Wealden Supergroup. The study confirms that distinct and distantly related spinosaur types lived in southern England during Early Cretaceous times.
Research survey finds that long working hours, inadequate staffing, and limited shift choice contribute to burnout and exhaustion among nursing staff. Staff with complete control over shift patterns are less likely to experience burnout, but this may not be feasible in 24/7 care settings.
A large-scale clinical trial has found that spironolactone is an effective treatment for persistent acne in women, offering an alternative to antibiotics. The study, funded by the National Institute for Health and Care Research, recruited over 400 women with acne that had persisted for more than six months.
The explosion, known as AT2021lwx, is more than ten times brighter than any known supernova and has lasted for nearly three years, compared to most supernovae which are only visibly bright for a few months. The researchers believe that the explosion is a result of a vast cloud of gas being violently disrupted by a supermassive black hole.
New research found that area-level deprivation is strongly associated with the risk of long COVID, with females having a higher risk. People working in healthcare and education sectors had the highest risk of long COVID compared to those in manufacturing and construction sectors.
A study using tooth enamel analyzed by laser ablation revealed that Neanderthals in western Europe hunted large animals, such as wild goat and horses, whereas humans consumed smaller creatures like rabbits and fish. The researchers estimated the territory size of both human groups, finding contrasting results.
A Cochrane review found that most antidepressants used to manage chronic pain lack sufficient evidence of their effectiveness, with only duloxetine showing reliable pain relief. The review also revealed that harms from many commonly recommended drugs have not been well studied, posing a global public health concern.
A climate-resilient bean genome unveiled potential to boost food security in drought-prone regions through improved genetic diversity and productivity. The sequencing of the hyacinth bean provides opportunities for targeted breeding to reduce anti-nutritional properties and increase its cultivation.
A new study reveals Ukraine's population is declining at an alarming rate due to low fertility, high mortality, and emigration. The crisis has worsened since the Russian invasion, leaving cities devastated and residents displaced.
Research finds that flash droughts are becoming more frequent due to human-caused climate change, posing a major challenge for climate adaptation. The transition to flash droughts is predicted to accelerate in a warmer future, with irreversible impacts on ecosystems.
A recent study published in BJOG found that nearly all women in England (97.5%) have at least one indicator of potential health risks during pregnancy, emphasizing the need for improved preconception care and policies to support women's overall well-being before pregnancy. The research highlights health disparities across different age...
A study found that the British public largely supports a ban on selling junk foods at checkouts, which is part of the UK government's efforts to tackle obesity. The legislation aims to create healthier shopping environments and reduce calorie consumption among children and adults alike.
A pioneering project aims to retrofit large vessels with ultramodern wing-sails to cut carbon emissions from the maritime sector. The research, funded by Innovate UK, will create software tools to predict fuel savings and support further investment in the UK's marine technology sector.