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Is the coronavirus outbreak of unnatural origins?

A modified Grunow-Finke assessment tool (mGFT) has been validated against previous outbreaks, outlining 11 criteria for determining if an outbreak is of unnatural origin. The tool helps identify unusual strain patterns, genetic manipulation, and peculiar geographic distribution, indicating potential artificial origin.

SourceSociety for Risk Analysis·JournalRisk Analysis·DateMar 26, 2020

Anticholinergic burden is associated with adverse outcomes in a middle-aged population

A study of over 500,000 middle-aged adults found that anticholinergic burden is associated with an increased risk of future adverse events such as falls, dementia, heart attacks, strokes, and deaths. The use of multiple medications with anticholinergic properties can have cumulative negative effects on the body.

SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateMar 9, 2020

App, AI work together to provide rapid at-home assessment of coronavirus risk

A new coronavirus app coupled with machine intelligence will enable individuals to get an at-home risk assessment based on their symptoms and travel history. The app will also provide real-time information to local and public health officials, aiding in the targeting of prevention and treatment initiatives.

SourceMedical College of Georgia at Augusta University·JournalInfection Control and Hospital Epidemiology·DateMar 5, 2020

Risks of later abortions on subsequent births

A study published in Acta Obstetricia et Gynecologica Scandinavica found that women who had late abortions experienced a higher risk of extremely preterm birth. The research included over 418,000 first-time mothers and observed an increased risk of very low birthweight among those with late abortion(s) compared to early abortion(s).

SourceWiley·JournalActa Obstetricia Et Gynecologica Scandinavica·DateMar 4, 2020

Algorithms 'consistently' more accurate than people in predicting recidivism, study says

A study by Stanford and UC Berkeley researchers found that algorithms are significantly more accurate than humans in predicting recidivism, approaching 90% accuracy. In contrast, human prediction rates were around 60%. The findings have important implications for criminal justice reform and the use of risk-assessment tools.

SourceUniversity of California - Berkeley·JournalScience Advances·DateFeb 14, 2020

Does tramadol increase hip fracture risk?

A UK patient database analysis found tramadol increases hip fracture risk by up to 1.5 new cases per 1000 person-years, compared to other pain medications. The study highlights the need for tramadol's fracture risk to be considered in clinical practice and treatment guidelines.

SourceWiley·JournalJournal of Bone and Mineral Research·DateFeb 5, 2020

The Lancet Planetary Health: Discriminatory redlining practices in the 1930s associated with present-day rates of emergency department visits due to asthma

Redlining practices in the 1930s are associated with higher rates of emergency department visits due to asthma, with a 39% increased risk in previously redlined neighbourhoods compared to non-redlined areas. Historical policies may have shaped neighbourhood development and air quality, contributing to asthma incidence.

SourceThe Lancet·JournalThe Lancet Planetary Health·DateJan 27, 2020

Does inflammatory bowel disease carry certain risks during pregnancy?

A recent analysis found that one-third of all pregnancies in women with inflammatory bowel disease (IBD) were delivered by Caesarean section, a two-fold increase compared to women without IBD. Women with IBD also face increased risks of gestational diabetes and preterm prelabour rupture of membranes.

SourceWiley·JournalAlimentary Pharmacology & Therapeutics·DateJan 8, 2020

Preoperative levels of heart proteins may help predict death or cardiac complications in patients undergoing noncardiac surgery

A cohort study found that preoperative N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations were independently associated with vascular death or myocardial injury at 30 days after surgery. Preoperative NT-proBNP thresholds improved discrimination and risk stratification for patients undergoing noncardiac surgery.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateDec 24, 2019

SUTD and collaborators developed novel methodology to predict spinal fractures in patients

A new computational clinical tool predicts osteoporotic vertebral fractures by analyzing patient-specific finite element analysis of functional spinal units from routine clinical scans. The method enables more accurate patient-specific analysis, paving the way for a spinal risk assessment tool and targeted early treatment strategies.

SourceSingapore University of Technology and Design·JournalThe Spine Journal·DateDec 19, 2019

New IOF-ESCEO position paper offers practical guidance for osteoporosis management

The new position paper provides practical guidance for managing postmenopausal osteoporosis, including easy-to-use algorithms that illustrate decision pathways based on absolute risk of fracture. The paper aims to offer the most appropriate interventions to patients, with a focus on targeting therapeutic interventions for low, high and...

SourceInternational Osteoporosis Foundation·JournalOsteoporosis International·DateNov 20, 2019

Adults in lower walkability neighborhoods found to have a higher predicted cardiovascular risk

A study by St. Michael's Hospital found that living in less walkable neighborhoods is associated with a higher predicted 10-year cardiovascular risk, up to 33% higher than in the most walkable areas. Individuals in these neighborhoods also experience higher blood pressure and increased odds of prior diabetes diagnosis.

SourceSt. Michael's Hospital·JournalJournal of the American Heart Association·DateOct 31, 2019

Predicting frailty, disability and death

A study by Brigham and Women's Hospital found that irregular fluctuations in daily motor activity can predict increased risk of frailty, disability, and mortality in older adults. The researchers analyzed data from 1,275 participants and found that random activity fluctuations were associated with a 31% increase in frailty risk, 15-25%...

SourceBrigham and Women's Hospital·JournalScience Translational Medicine·DateOct 30, 2019

Large income change associated with cardiovascular disease risk

A significant association between changes in income and cardiovascular disease (CVD) risk was found in this observational study. Participants who experienced a 50% or more decrease in income were at higher risk of developing CVD, including heart attack, coronary heart disease, and stroke, over an average follow-up period of 17 years.

SourceJAMA Network·JournalJAMA Cardiology·DateOct 9, 2019

Medication adherence may affect risk of hospitalization and early death

A recent review found that individuals with good medication adherence have a lower risk of needing hospitalisation due to any cause (17% reduction) and long-term mortality risk (21% reduction). Medication non-adherence is associated with increased risks of adverse health outcomes in older populations.

SourceWiley·JournalBritish Journal of Clinical Pharmacology·DateSep 5, 2019