Articles tagged with Cancer Treatments
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Researchers found that a program designed to reduce stress in cancer patients can be taught to therapists across the country and effectively improves mood. The study involved 15 sites and 158 patients with various types of cancer, showing significant improvement on measures of mood and physical activity.
Physicists from the Helmholtz-Zentrum Dresden-Rossendorf have developed a new type of diagnostics to investigate the complex acceleration process of electrons and ions in hot plasma created by ultra-powerful lasers. The results, published in Physical Review X, confirm the spatial and temporal resolution of the diagnostic method.
A novel cosmetic product has shown promise in covering facial scars, with patients reporting improved satisfaction with their appearance. The treatment's effectiveness varies depending on the location and degree of scarring, but the results suggest a potential long-term solution for those affected.
Prescription drug shortages lead to estimated $230 million in annual costs due to rising prices and substitution drugs. Researchers found price increases reflect manufacturers' opportunistic behavior during shortages.
A new study reveals how KSHV protein LANA drives chromosomal instability, promoting cell proliferation and aneuploidy. The findings identify NNLS as a promising target for antiviral therapies.
Researchers at University of Helsinki have identified a key regulator of kidney development, revealing how MAPK activity influences nephron number in mature kidneys. This discovery holds promise for developing stem cell-based regenerative therapies as novel treatments for renal diseases.
Researchers have identified mutations defining two common subtypes of MPAL, B/myeloid and T/myeloid, and shown that some patients may benefit from targeted therapies. The study provides a genetically based framework for designing clinical trials to develop more effective treatments.
Researchers developed a new framework combining three methods to find large DNA mutations in cancer cells. The approach reveals how these mutations contribute to cancer development and can help predict effective treatment plans.
A new study published in CANCER journal reveals that social support is the most decisive factor associated with life satisfaction among young patients with cancer. The research found that young adults with cancer who have strong social connections experience higher life satisfaction, regardless of other factors.
Scientists developed a bioadhesive, wirelessly-powered implant emitting light to kill cancer cells, promising effective treatment for internal organ cancers. The device overcomes limitations of conventional photodynamic therapy by providing continuous, local light delivery.
Researchers created a new diagnostic tool using advanced analyses to identify tumors with unknown origins. The tool helped diagnose a metastasis of melanoma residing in the lung, leading to effective treatment with BRAF inhibitors.
A new four-year study aims to decrease psychological distress in cancer patients and their family caregivers during treatment using a sequential multiple assignment randomized trial. The study will employ two interventions: a printed symptom management handbook and a telephone counseling intervention.
Researchers developed a predictive model using liquid biopsies and serial blood samples from patients with advanced colorectal cancer treated with anti-EGFR therapies. The model accurately predicted personalized waiting times for disease progression, outperforming traditional tumor genotyping methods.
A new study finds that clinical quality registries for surgery often exclude treatment-related adverse events, leading to misleading conclusions. The study analyzed data from Finland and compared it with US and UK quality registers.
Osaka University researchers successfully delivered microRNAs to immune response cells in inflamed intestinal tracts using a super carbonate apatite (sCA), reducing inflammatory cytokines. The study showed that sCA could be used to treat a wide range of immunity and allergic disorders caused by immune responses.
Researchers at NUST MISIS have developed a system that improves cancer diagnosis accuracy and provides opportunities for targeted therapy. The magnetoferritin compound, introduced into the body before diagnosis, enhances contrast signals in imaging and targets tumor cells for destruction.
A new study identifies HIF1A, a gene that regulates metabolic changes and oxygen levels in cells, as a potential therapeutic target for treating myelodysplastic syndromes (MDS). The researchers found that inhibiting HIF1A reversed a broad spectrum of MDS symptoms in genetic mouse models.
ReMix uses wireless signals to pinpoint the location of ingestible implants inside the body with centimeter-level accuracy. This technology has the potential to improve proton therapy cancer treatment by allowing doctors to track tumors in real-time and deliver targeted radiation.
Research found that STAT3 is constitutively activated in CAEBV-infected T- or NK-cells, promoting cell survival and inflammation. Ruxolitinib inhibition blocks survival and reduces pro-inflammatory cytokine production, suggesting a potential therapeutic target for this fatal disorder.
Researchers at the University of Copenhagen have developed a new method to diagnose cancer at its early stages using a malaria protein. The method retrieves individual cancer cells from blood samples, catching them in greater numbers than existing methods, allowing for earlier detection and improved treatment outcomes.
Researchers at H. Lee Moffitt Cancer Center suggest that lowering pH inside cancer cells can slow down the growth and spread of the disease. By analyzing how variations in pH affect metabolic enzymes, they identified potential therapeutic targets for breast cancer treatment.
Researchers have identified 85 genes essential for fission yeast cells to maintain their ability to divide after being starved of nitrogen. The study sheds light on the genetic network required for resting cells like cancer stem cells to reactivate and has potential applications in developing new therapies to treat cancer. This discove...
Researchers discovered a molecular switch, PI3KC2A, that regulates signaling cascades in cells. Activating or inhibiting this enzyme may lead to new therapies for cancer and diabetes. The study's findings provide unprecedented insight into cellular processes and offer potential targets for treatment.
Researchers have identified a blood biomarker called KIM-1 that can predict the risk of developing kidney cancer over the next 5 years. Measuring levels of KIM-1 in the blood may help detect kidney cancer earlier, potentially improving survival rates.
Research suggests that psychedelic drugs can help treat disorders such as social anxiety, depression, and PTSD when used in combination with psychotherapy. Studies have shown promising results for MDMA, psilocybin, and ayahuasca in reducing symptoms of anxiety, depression, and disordered eating.
Researchers at the University of Exeter discovered new compounds that can reverse key aspects of human cell aging by targeting mitochondria. The findings, published in the journal Aging, show a significant reduction in senescent cells and potential therapeutic applications for anti-aging treatments.
A study found that reducing NOVA1 gene activity inhibits telomerase, leading to shorter telomeres and reduced tumor growth in non-small cell lung cancer. The research provides a new approach to targeting cancer cells and may lead to more effective treatments for this prevalent form of age-related cancer.
Research suggests that early childhood trauma may be a risk factor for anxiety and depression in adults diagnosed with head/neck cancer. The study found that patients who experienced emotional neglect were more likely to have advanced cancer stages, while physical child abuse was linked to increased anxiety levels.
Researchers identify a new mechanism used by Henipaviruses to hijack the DNA-damage response machinery, allowing them to prosper in cells. This discovery may lead to the development of new anti-viral therapies.
Jackson Laboratory Assistant Professor Mingyang Lu has developed a computational approach called RACIPE to capture genetic events in cellular decision-making. The algorithm could have broad impact on basic research and designing new therapeutic interventions in genomic medicine.
Medical nutrition therapy (MNT) is crucial for slowing chronic kidney disease progression and reducing healthcare costs. Despite its importance, only 10% of non-dialysis kidney patients receive MNT, which includes individualized nutrition assessment and personalized dietary education.
A computational study has shown that cancer cells proliferate less and are more vulnerable to acidic conditions than initially thought. The researchers have identified potential therapeutic targets by analyzing how variations in pH affect metabolic enzyme activity, providing opportunities for new treatments.
A large-scale retrospective study has shown that nearly doubling the number of lymph nodes removed during operations for right-sided colon cancers improves the survival rate for these patients. The study found improved outcomes when at least 22 lymph nodes were harvested, with a 20% increase in five-year survival rates.
Researchers explore two approaches to stem cell therapy for Parkinson's disease, one using patient-specific induced pluripotent stem cells and the other utilizing parthenogenetic-derived neural stem cells. The latter approach offers advantages in terms of reduced immunogenicity and evasion of ethical issues surrounding embryos.
A new study published in the American Cancer Society journal reveals that many patients with cancer face significant financial difficulties due to treatment costs. Despite medical oncologists, surgeons, and radiation oncologists reporting some engagement with patients about financial concerns, unmet patient needs persist.
A new study published in the British Journal of Surgery found that breath analyses can identify pancreatic cancer compounds. Researchers detected 12 specific volatile organic compounds indicative of pancreatic cancer, offering potential for early detection and treatment.
Football training has been linked to improved bone mineral density in elderly men with prostate cancer, particularly in those undergoing androgen deprivation therapy. The study found no association with body composition or physical functioning.
Research highlights the physiological and pathophysiological functions of olfactory receptors in human tissues, including their potential applications in cancer diagnosis and therapy. The receptors also regulate skin regeneration, intestinal digestion, and hair growth.
A study published in the Journal of Thoracic Oncology found that active surveillance of lung subsolid nodules can reduce unnecessary surgery and overtreatment. Lung cancers arising from these nodules rarely led to death, suggesting they can be a biomarker for cancer risk.
Scientists have discovered that CRISPR/Cas9 gene editing can cause extensive mutations, including DNA deletions and insertions, leading to major implications for its use in gene therapies. The study highlights the need for specific testing and caution when using CRISPR/Cas9 in therapeutic applications.
The American Cancer Society and NFL have awarded $3.2 million in grant funding to address breast cancer disparities among women of color. The grants will support timely access to follow-up care and high-quality breast cancer screening for underserved women.
Researchers found at least one rhesus gammaherpesvirus in all but one tumor, with RLCV associated with cancer risk and RFHV levels increasing over time. The study suggests that gammaherpesviruses contribute to tumor development in SIV/SHIV-infected macaques.
A class of enzymes, DYRK3, has been found to promote mixing of phases in cells during division, ensuring correct distribution of genetic material, organelles, and cell contents. This process is crucial for preventing errors like those seen in cancer and neurodegenerative diseases.
A study of over 250,000 British women found no overall increased risk of invasive breast or womb cancer after assisted reproduction. However, small increased risks of non-invasive breast and ovarian tumours were detected, with the former linked to a greater number of treatment cycles.
Researchers at Cincinnati Children's Hospital Medical Center have found a potential therapeutic target for acute myeloid leukemia (AML), a deadly blood cancer with a dismal survival rate. By targeting the F-box protein Skp2, they were able to kill AML cells and induce healthy white blood cell regeneration in preclinical tests.
Researchers at Kumamoto University identified optimal PEF conditions for increasing cell membrane permeability to calcium. The study found that larger electric fields produced high calcium intake rates, while smaller fields showed undetectable intake rates initially followed by increased rates.
A new study by IRB Barcelona researchers reveals that myeloid cells use p38 protein signalling to support inflammation-associated colon cancer. The study suggests IGF-1 as a potential therapeutic target in combination with prior detection of inflammatory infiltration in biopsies.
The American Cancer Society is outlining its vision for cancer control in the decades ahead, aiming to eliminate socioeconomic disparity to prevent one in four cancer deaths in the US. The blueprint identifies key areas such as prevention, screening, and early detection, and emphasizes the need to address disparities in cancer outcomes.
Researchers found that activating a specific type of neuron in the hypothalamus can trigger hot-flash-like symptoms in mice, regardless of gender. This discovery validates previous research on hot flashes and suggests a neurological target for preventing them.
The American Society of Human Genetics (ASHG) recognizes Dr. Andrew Adey's contributions to cancer development and progression research. His novel single-cell technologies are being used worldwide to understand epigenetics and disease models.
Researchers from UAB successfully used gene therapy to treat type 2 diabetes and obesity in mice by inducing the production of FGF21, a hormone that maintains correct energy metabolism. The treatment led to weight loss and improved insulin sensitivity, reducing the risk of related comorbidities.
New Zealand scientists have developed a revolutionary 3D colour medical scanner that provides far greater detail of the body's chemical components. The MARS spectral x-ray scanner will revolutionise medical imaging globally, enabling more accurate diagnosis and personalisation of treatment for diseases like cancer and heart disease.
Extended tamoxifen therapy for 10 years increases the risk of developing endometrial cancer by two-fold compared to standard 5-year treatment. Screening for endometrial cancer may be necessary in patients receiving extended tamoxifen therapy.
The University of Hawai'i Cancer Center has been awarded a $6 million Cancer Center Support Grant to fund research at the Center. The renewal of its National Cancer Institute (NCI) designation recognizes the Center's unique contributions to cancer research and care in Hawaii, particularly for diverse ethnic populations.
A research team has used an integrated structural biological approach to elucidate the maturation of a cancer-causing microRNA in gene regulation. Understanding this process may help develop new therapies for cancer treatment.
Men treated with ICSI for infertility have a significantly higher risk of developing early-onset prostate cancer, which is considered more aggressive. The study found that this risk is associated with male sub-fertility, not the ICSI procedure itself.
Researchers at BIDMC developed the BE3A score to predict improvement in liver function after DAA therapy for patients with decompensated cirrhosis. The online scoring system assesses 5 baseline factors to provide a shared decision-making tool for physicians and patients.
A team of researchers from CSIRO Australia has identified a new gene called C6 that regulates the body's immune response to infection and disease. The discovery could lead to targeted therapies for various diseases, including cancer, diabetes, and inflammatory disorders.
A study of over 32,000 cancer survivors found an increased risk of endocrine diseases such as thyroid disease and diabetes. Researchers examined the long-term consequences of cancer treatment in adolescents and young adults.
Researchers have identified a new gene-activation pathway caused by lipids associated with coronary artery disease, which could help identify new directions in research and drug development. The study found that exposure to lipids activates the MTHFD2 gene in the walls of blood vessels.