Articles tagged with Cancer
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at UCSF found that certain gut bacteria can reduce chemotherapy side effects by clearing excess drugs and producing the protective vitamin K2. Patients with more beneficial bacteria had fewer side effects, suggesting that probiotics may help mitigate chemotherapy's impact.
Researchers have developed a new treatment combining venetoclax and inobrodib that shows promising results in killing B-ALL cells, potentially reducing toxic chemotherapy needs. The approach could be less toxic than current treatments and effective in all age groups.
UT Dallas bioengineers have created an enhanced light-activated immunotherapy approach to target advanced stomach cancer. Lab-designed molecules are primed with far-red or near-infrared light to activate the immune system against stubborn cancer cells, reducing side effects.
US survivors of adolescence and young adult cancer experience significantly worse mental health outcomes into middle age and older adulthood. Cancer clinicians should acknowledge this mental health burden and take steps to address it.
Researchers from Sylvester will present on various cancer-related topics, including multiple myeloma, hematopoietic stem cell transplantation, and melanoma. The presentations focus on innovative treatments and supportive care interventions.
Research reveals specific mtDNA mutations drive cancer initiation, impairing mitochondrial function and increasing ROS production. Elevated oncogenic potential is observed in cells with low to moderate levels of MT-ND5 heteroplasmy.
A recent study identifies LPCAT1 as a critical culprit in TNBC's aggressive behavior, which can be silenced with siRNA-delivering nanoparticles. This approach starves tumors of their energy supply, dramatically reducing tumor growth and lung metastasis.
A nationwide cohort study found that immune checkpoint inhibitors significantly increase the risk of myocarditis in NSCLC patients, with a 7.4-fold increase in risk compared to non-users. Cardiac monitoring for at least six months following ICI initiation is recommended.
A study found that blood cancer survivors are more likely to face financial hardship and take fewer medications due to high-cost immunotherapy treatments. Financial strain affects both Medicare-insured and uninsured patients, highlighting the need for better financial support and policy strategies.
The American Society for Radiation Oncology (ASTRO) will host its 67th Annual Meeting in San Francisco from September 27 to October 1, 2025. The meeting will feature over 2,500 research presentations and posters on advances in radiation oncology and non-cancer indications.
A new clinical trial has shown that a lower dose of radiotherapy can lead to higher levels of complete disappearance of cancer and fewer short-term side effects. The treatment approach, led by Professor David Sebag-Montefiore, aims to reduce the burden on patients and healthcare systems.
Researchers found that stereotactic body radiotherapy (SBRT) is as safe as conventional treatment, with similar side effects and quality of life. SBRT shortens treatment time and may have biological advantages in targeting prostate cancer.
A new study from Uppsala University found that people with high fitness levels in late adolescence have a lower risk of dying prematurely, but the association between physical fitness and reduced mortality risk may be overstated. The researchers examined data from over 1 million Swedish men and found no significant difference in the ri...
A study by Mass General Brigham found that patients with glioblastoma who received gabapentin lived longer than those who didn't. The medication was shown to confer a four-month survival benefit, with patients on gabapentin surviving an average of 16 months compared to 12 months for those without the drug.
Scientists discovered that taurine drives leukemia growth by promoting glycolysis and is produced by normal cells in the bone marrow microenvironment. Researchers identified taurine transporter expression as essential for leukemia cell growth, leading to potential new therapeutic targets.
The National Comprehensive Cancer Network (NCCN) is joining forces with global organizations to address gaps in cancer control plans, promoting data-driven decision-making and comprehensive implementation. The Cancer Planners Forum aims to optimize care for people touched by cancer globally.
Researchers created a new nanoparticle that combines focused ultrasound and chemotherapy to destroy tumors more precisely and prevent recurrence. The treatment shows promising results in preclinical models, offering a potential breakthrough in cancer therapy.
A new study found that adults diagnosed with type 1 diabetes after age 40 have a higher risk of cardiovascular disease and death compared to those diagnosed earlier. Poor glucose control, obesity, and smoking are the main risk factors identified in the study.
A systematic review and meta-analysis found that individuals with blood type A have a significantly higher risk of developing breast cancer compared to those with blood type O. The research, which pooled data from over 13,000 breast cancer patients and 717,000 controls, suggests an 18% increased risk associated with blood type A.
Researchers at the University of Chicago Medicine discovered a new phenomenon where high doses of radiation cause growth in existing metastatic tumors. The 'badscopal effect' is attributed to increased production of amphiregulin, which weakens the immune system and makes cancer cells more resistant.
Breast cancer remains a significant health challenge worldwide, with nanotechnology offering a ray of hope. Nanoparticles improve diagnostic imaging, biomarker detection, and therapy by enhancing drug solubility, stability, and targeted delivery.
A new study identified six distinct breast tissue patterns associated with an increased risk of invasive breast cancer, particularly among Black women. The radiomic phenotypes may help predict the likelihood of false-negative mammograms or interval cancer diagnoses.
Researchers found that x-ray sterilization effectiveness differs depending on dose rate and bacterial nutrient conditions. Long-term low-dose irradiation was more effective in nutrient-poor environments, while short-term high-dose irradiation achieved higher efficiency in nutrient-rich environments.
DiffInvex identifies evolutionary shifts in driver gene repertoires during tumorigenesis and chemotherapy, pinpointing mutational escape routes that let cancers resist treatment. The framework reveals which genes may ignite resistance to anticancer drugs, suggesting a core circuitry boosting strategy.
Researchers have developed a new compound, SHP1705, that selectively attacks glioblastoma stem cells by hijacked circadian clock proteins. The compound was found to be safe and well-tolerated in humans during a phase 1 clinical trial.
The study demonstrated the diagnostic utility of endobronchial ultrasound elastography for detecting benign and malignant lymph nodes. The combined index of elastography grading score and short diameter yielded an area under the receiver operating characteristic curve of 0.702, indicating moderate accuracy.
A study led by MUSC Hollings Cancer Center researcher Amanda Palmer found that young males, especially those who have used cigarettes or e-cigarettes before, are more likely to use oral nicotine pouches. Although usage is relatively low, the trend suggests a potential beneficial alternative to combustible cigarettes.
Researchers found that GLP-1 receptor agonists have a direct effect on reducing obesity-related cancer beyond weight-loss, with a 41% lower relative risk compared to bariatric surgery. The study also suggests that these medications work through multiple mechanisms, including reducing inflammation.
Researchers discovered that METTL3, an oncogene, regulates the expression of SMAD4 via miR-146a-5p in OSCC. This pathway can potentially have therapeutic implications for treating oral squamous cell carcinoma.
A new $4 million grant will test whether Prostate Specific Membrane Antigen (PSMA)-Positron Emission Tomography (PET) Computed Tomography (CT) can improve prostate cancer monitoring while reducing screening-related harms. The study aims to reduce the need for biopsies in men with low- or intermediate-risk prostate cancers.
Researchers found that phospholipids in ascites fluid disrupt immune cell function, particularly NK cells, leading to impaired anti-tumor activity. Blocking these lipids can restore NK cell activity, providing a promising therapeutic target.
Recent advances and challenges in T cell immunotherapy highlight the need for deeper understanding of T cell fate determination mechanisms to overcome immunotherapy resistance. Key regulatory factors, transcription factors, and metabolic pathways govern T cell differentiation and function.
Researchers discovered that ascites fluid produced by ovarian cancer suppresses cytotoxic lymphocytes, crippling immune cells' ability to kill cancer cells. Fats in ascites cripple NK cells, T cells, and innate T cells, which are attractive candidates for cellular immunotherapies.
A new study suggests that multi-strain probiotics can alleviate chemotherapy-related side effects such as fatigue, nausea, and weakness. Probiotics have been shown to improve blood urea nitrogen levels and enable patients to perform daily activities more independently.
A new AI tool, FaceAge, estimates a person's biological age from their facial characteristics, which is associated with cancer survival outcomes. The tool outperforms clinicians in predicting short-term life expectancies for patients receiving palliative radiotherapy.
The introduction of standardized criteria for amino acid PET in brain metastases diagnosis and treatment could improve patient care and accelerate innovative treatment strategies. The new criteria may allow a more precise distinction between true tumour changes and therapy-related effects.
Researchers discovered 500 cryptic peptides found only in pancreatic tumors, which could be targeted by vaccines or engineered T cells to attack the cancer. The peptides were identified using immunopeptidomics and shown to slow down tumor growth in mice.
A single blood test could identify early-stage cancer in up to half of cases, potentially preventing late-stage disease and improving patient outcomes. Regular MCED testing showed more favourable diagnostic rates than usual care alone, with annual screenings having a higher impact on stage shift.
The study found increasing incidence rates for five cancer types without corresponding increases in late-onset age groups. The greatest increases were seen in female breast cancer, colorectal cancer, kidney cancer, and uterine cancer.
A systematic review found a strong association between ultra-processed food consumption and adverse health outcomes. The study suggests that limiting intake of such foods may offer measurable health benefits.
A study found moderate elevations of certain PFAS in health care workers' blood, with notably higher odds of detecting Sb-PFOA and PFDoA compared to other professions. Firefighters had the highest concentrations of PFAS, specifically concentrations of PFHxS, Sm-PFOS, n-PFOS and PFHpS.
A new study by UCLA researchers shows that advanced MRI imaging and targeted focal therapy can help many men with low- to intermediate-risk prostate cancer safely stay on active surveillance long-term, avoiding follow-up biopsies and delaying or avoiding invasive treatments. The findings suggest that routine follow-up biopsy can now be...
A European research team will explore radiation therapy approaches to improve treatment outcomes and prevent secondary tumors in adolescents and young adults. The KAYAC+ project aims to investigate the clinical results of particle therapy and its impact on cancer development.
A new study reveals that over half of Black and Latina women reported using personal care products with formaldehyde-releasing preservatives, highlighting critical safety gaps in product regulation. The study found that these chemicals are present in a wide range of products, including shampoo, lotions, and eyelash glue.
A study found that removing ovaries and fallopian tubes in women with BRCA1 and BRCA2 genetic variants significantly reduces the risk of early death from cancer. This procedure, known as bilateral salpingo-oophorectomy (BSO), also decreases the risk of developing a second cancer without any serious side effects.
The ESMO Breast Cancer 2025 congress will cover topics such as circulating tumour DNA, immunotherapies, and emerging therapies for managing breast cancer. The event will feature key findings on predictive biomarkers, ctDNA, and tumour-infiltrating lymphocytes.
A study published in Human Reproduction found that healthy childhood diets are associated with delayed onset of menstruation, independent of body mass index (BMI) or height. The research suggests that a diet high in fruits, vegetables, and whole grains may help reduce the risk of chronic diseases such as diabetes and breast cancer.
Researchers identified ADH4 as a key suppressor of HCC and found that silencing it increases tumor growth; forced ADH4 expression reverses oncogenic traits. RA production counteracts the Wnt/β-catenin signaling pathway, driving cellular proliferation.
A study led by the Badalona Neuromuscular Research Group found that HDAC11 deficiency reduces muscle mass loss, promotes muscle regeneration, and improves overall muscle function in aged murine models. This discovery proposes a new therapeutic strategy to slow down age-related muscular decline and promote healthier ageing.
A new AI tool, SALSA, has been developed to automate the detection and monitoring of liver tumors with high precision. The tool, which uses deep learning algorithms, demonstrates superior accuracy in cancer detection and quantification of tumor burden, surpassing state-of-the-art models.
The NCCN Policy Summit brought together experts to discuss ways to strengthen collaborative cancer care, from early detection to survivorship. Key findings include the need for better communication and coordination between primary care and oncology providers.
A new study published in the Journal of the National Cancer Institute suggests that artificial intelligence can help detect interval breast cancers earlier, potentially reducing their rates by 30%. The research used AI software to analyze mammograms and identify subtle signs of cancer that were missed by radiologists.
Researchers found AI outperformed physicians in answering GI cancer questions, with oncologists preferring ChatGPT's responses nearly 80% of the time. Additionally, fewer patients are getting surgery for benign colon polyps as endoscopic techniques rise, reducing serious complications and mortality rates.
Researchers found that a chemical modification on messenger RNAs triggers disposal while being read by the ribosome, but during cell stress, this process is halted, allowing stress-response proteins to accumulate and help cells recover. The study may have implications for cancer therapies targeting m6A modifications.
Anal cancer is increasing rapidly among older, white and Hispanic women due to HPV vaccination delays. The study found a significant increase in anal cancer rates for these groups, reaching 11.4 cases per 100,000 in 2021.
A McGill University-led study found that 75% of Canadian adults spend at least 30 minutes in the sun on summer days, with nearly half staying out for two hours or more. Young adults are more likely to get sunburned and use tanning beds, making them less likely to wear protective clothing.
Researchers investigated the clinical outcomes of concurrent TTFields therapy with CRT in patients with newly diagnosed glioblastoma, finding no significant difference in survival outcomes compared to adjuvant therapy. The study also showed comparable safety profiles for both treatment groups.
Researchers at Osaka Metropolitan University found that plasma-activated medium reduces synovial sarcoma tumor growth in human cells and mice, with no obvious side effects. The treatment was verified through in vitro and in vivo tests, offering a new potential treatment option for this rare form of cancer.
A recent study has identified the 'cell of origin' of lung squamous cell carcinoma (LUSC), a second most common type of lung cancer among smokers. The research found that basal cells expressing the gene Krt5 become dominant in the trachea and eventually invade large areas of the lung, forming tumors.
Researchers from the University of Southampton engineered a new type of super-strong antibody that triggers a stronger response from the immune system compared to naturally produced antibodies. The study confirms that making subtle increases in rigidity stimulates immune activity, creating a powerful immune response against disease.